{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:12:01Z","timestamp":1789153921209,"version":"build-2803163510"},"reference-count":103,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AAPS PharmSciTech"],"DOI":"10.1208\/s12249-026-03525-0","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:34:34Z","timestamp":1789148074000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Thermogelling Hydrogel for Sustained Topical Delivery of Quercetin for the Treatment of Atopic Dermatitis"],"prefix":"10.1208","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4576-6630","authenticated-orcid":false,"given":"Saiswari","family":"Dwibedi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2743-9965","authenticated-orcid":false,"given":"Ganesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5357-0256","authenticated-orcid":false,"given":"Sree Prakash","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3541-6893","authenticated-orcid":false,"given":"Nishi","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9824-6378","authenticated-orcid":false,"given":"Shweta","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0741-7348","authenticated-orcid":false,"given":"Nishat Parveen","family":"Siddiqui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9183-9613","authenticated-orcid":false,"given":"Manoj","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8735-3954","authenticated-orcid":false,"given":"Ravi Shankar","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"issue":"4","key":"3525_CR1","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.aller.2017.07.002","volume":"46","author":"E Serra-Baldrich","year":"2018","unstructured":"Serra-Baldrich E, De Frutos J, J\u00e1uregui I, Armario-Hita J, Silvestre J, Herraez L, et al. Changing perspectives in atopic dermatitis. Allergol Immunopathol (Madr). 2018;46(4):397\u2013412.","journal-title":"Allergol Immunopathol (Madr)"},{"key":"3525_CR2","doi-asserted-by":"crossref","unstructured":"Campos ALB, Ara\u00fajo FMd, Santos MALDd, Santos AdASd, Pires CAA. Impact of atopic dermatitis on the quality of life of pediatric patients and their guardians. Revista Paulista de Pediatria. 2017;35:05\u201310.","DOI":"10.1590\/1984-0462\/;2017;35;1;00006"},{"issue":"6","key":"3525_CR3","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1089\/derm.2024.0165","volume":"36","author":"CB Migliavaca","year":"2025","unstructured":"Migliavaca CB, Lazzarini R, Stein C, Escher GN, de Gaspari CN, Dos Santos HWG, et al. Prevalence of atopic dermatitis: a systematic review and meta-analysis. Dermatitis. 2025;36(6):575\u201382.","journal-title":"Dermatitis"},{"key":"3525_CR4","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3510","author":"S Bylund","year":"2020","unstructured":"Bylund S, von Kobyletzki LB, Svalstedt M, Svensson \u00c5. Prevalence and incidence of atopic dermatitis: a systematic review. Acta Derm Venereol. 2020. https:\/\/doi.org\/10.2340\/00015555-3510.","journal-title":"Acta Derm Venereol"},{"issue":"6","key":"3525_CR5","doi-asserted-by":"publisher","first-page":"747","DOI":"10.5114\/ada.2023.133818","volume":"40","author":"J Sroka-Tomaszewska","year":"2023","unstructured":"Sroka-Tomaszewska J, Buli\u0144ska B, Wilkowska A, Nowicki R, Trzeciak M. Dupilumab for the treatment of moderate and severe atopic dermatitis: real-life experience. Adv Dermatol Allergol. 2023;40(6):747\u201352.","journal-title":"Adv Dermatol Allergol"},{"issue":"2","key":"3525_CR6","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.anai.2023.09.009","volume":"132","author":"N Stefanovic","year":"2024","unstructured":"Stefanovic N, Irvine AD. Filaggrin and beyond: new insights into the skin barrier in atopic dermatitis and allergic diseases, from genetics to therapeutic perspectives. Ann Allergy Asthma Immunol. 2024;132(2):187\u201395.","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"3525_CR7","doi-asserted-by":"publisher","first-page":"409","DOI":"10.5114\/pdia.2014.44017","volume":"32","author":"M Oszukowska","year":"2015","unstructured":"Oszukowska M, Michalak I, Gutfreund K, Bienias W, Matych M, Szewczyk A, et al. Role of primary and secondary prevention in atopic dermatitis. Adv Dermatol Allergol\/Post\u0119py Dermatologii i Alergologii. 2015;32(6):409\u201320.","journal-title":"Adv Dermatol Allergol\/Post\u0119py Dermatologii i Alergologii"},{"issue":"3","key":"3525_CR8","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1111\/cea.12495","volume":"45","author":"W Peng","year":"2015","unstructured":"Peng W, Novak N. Pathogenesis of atopic dermatitis. Clin Exp Allergy. 2015;45(3):566\u201374.","journal-title":"Clin Exp Allergy"},{"issue":"4","key":"3525_CR9","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1007\/s13671-018-0235-8","volume":"7","author":"Q Liu","year":"2018","unstructured":"Liu Q, Mazhar M, Miller LS. Immune and inflammatory reponses to Staphylococcus aureus skin infections. Curr Dermatol Rep. 2018;7(4):338\u201349.","journal-title":"Curr Dermatol Rep"},{"key":"3525_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/life13061419","author":"L Lugovi\u0107-Mihi\u0107","year":"2023","unstructured":"Lugovi\u0107-Mihi\u0107 L, Me\u0161trovi\u0107-\u0160tefekov J, Poto\u010dnjak I, Cindri\u0107 T, Ili\u0107 I, Lovri\u0107 I, et al. Atopic dermatitis: disease features, therapeutic options, and a multidisciplinary approach. Life. 2023. https:\/\/doi.org\/10.3390\/life13061419.","journal-title":"Life"},{"issue":"6","key":"3525_CR11","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1080\/14712598.2024.2368192","volume":"24","author":"E David","year":"2024","unstructured":"David E, Hawkins K, Shokrian N, Del Duca E, Guttman-Yassky E. Monoclonal antibodies for moderate-to-severe atopic dermatitis: a look at phase III and beyond. Expert Opin Biol Ther. 2024;24(6):471\u201389.","journal-title":"Expert Opin Biol Ther"},{"issue":"1","key":"3525_CR12","doi-asserted-by":"publisher","first-page":"151","DOI":"10.3390\/biom15010151","volume":"15","author":"HOA Alharbi","year":"2025","unstructured":"Alharbi HOA, Alshebremi M, Babiker AY, Rahmani AH. The role of quercetin, a flavonoid in the management of pathogenesis through regulation of oxidative stress, inflammation, and biological activities. Biomolecules. 2025;15(1):151.","journal-title":"Biomolecules"},{"issue":"7","key":"3525_CR13","doi-asserted-by":"publisher","DOI":"10.3390\/ph16071020","volume":"16","author":"F Aghababaei","year":"2023","unstructured":"Aghababaei F, Hadidi M. Recent advances in potential health benefits of quercetin. Pharmaceuticals (Basel). 2023;16(7):1020.","journal-title":"Pharmaceuticals (Basel)"},{"key":"3525_CR14","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3997190","author":"G Wang","year":"2022","unstructured":"Wang G, Wang Y, Yao L, Gu W, Zhao S, Shen Z, et al. Pharmacological activity of quercetin: an updated review. Evid Based Complement Alternat Med. 2022. https:\/\/doi.org\/10.1155\/2022\/3997190.","journal-title":"Evid Based Complement Alternat Med"},{"issue":"5","key":"3525_CR15","doi-asserted-by":"publisher","first-page":"5011","DOI":"10.1007\/s00210-024-03722-3","volume":"398","author":"T Okselni","year":"2025","unstructured":"Okselni T, Septama AW, Juliadmi D, Dewi RT, Angelina M, Yuliani T, et al. Quercetin as a therapeutic agent for skin problems: a systematic review and meta-analysis on antioxidant effects, oxidative stress, inflammation, wound healing, hyperpigmentation, aging, and skin cancer. Naunyn Schmiedebergs Arch Pharmacol. 2025;398(5):5011\u201355.","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"2","key":"3525_CR16","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1089\/ped.2019.1137","volume":"33","author":"B Beken","year":"2020","unstructured":"Beken B, Serttas R, Yazicioglu M, Turkekul K, Erdogan S. Quercetin improves inflammation, oxidative stress, and impaired wound healing in atopic dermatitis model of human keratinocytes. Pediatr Allergy Immunol Pulmonol. 2020;33(2):69\u201379.","journal-title":"Pediatr Allergy Immunol Pulmonol"},{"issue":"12","key":"3525_CR17","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.3390\/polym14122379","volume":"14","author":"R Fan","year":"2022","unstructured":"Fan R, Cheng Y, Wang R, Zhang T, Zhang H, Li J, et al. Thermosensitive hydrogels and advances in their application in disease therapy. Polymers (Basel). 2022;14(12):2379.","journal-title":"Polymers (Basel)"},{"key":"3525_CR18","doi-asserted-by":"crossref","unstructured":"Pooja B. Thermosensitive in situ gels: Mechanisms, properties, and applications in drug delivery. IJSAT-Int J Sci Technol. 2025;16(3).","DOI":"10.71097\/IJSAT.v16.i3.8352"},{"issue":"3","key":"3525_CR19","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics10030159","volume":"10","author":"E Giuliano","year":"2018","unstructured":"Giuliano E, Paolino D, Fresta M, Cosco D. Mucosal applications of poloxamer 407-based hydrogels: an overview. Pharmaceutics. 2018;10(3):159.","journal-title":"Pharmaceutics"},{"issue":"1","key":"3525_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/srep24112","volume":"6","author":"W Wang","year":"2016","unstructured":"Wang W, Wat E, Hui PC, Chan B, Ng FS, Kan C-W, et al. Dual-functional transdermal drug delivery system with controllable drug loading based on thermosensitive poloxamer hydrogel for atopic dermatitis treatment. Sci Rep. 2016;6(1):24112.","journal-title":"Sci Rep"},{"issue":"2","key":"3525_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.phyplu.2022.100257","volume":"2","author":"K Wadhwa","year":"2022","unstructured":"Wadhwa K, Kadian V, Puri V, Bhardwaj BY, Sharma A, Pahwa R, et al. New insights into quercetin nanoformulations for topical delivery. Phytomedicine Plus. 2022;2(2):100257.","journal-title":"Phytomedicine Plus"},{"key":"3525_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2023.104727","volume":"86","author":"B Tzankov","year":"2023","unstructured":"Tzankov B, Voycheva C, Tosheva A, Stefanova D, Tzankova V, Spassova I, et al. Novel oleogels for topical delivery of quercetin based on mesoporous silica MCM-41 and HMS particles. J Drug Deliv Sci Technol. 2023;86:104727.","journal-title":"J Drug Deliv Sci Technol"},{"key":"3525_CR23","doi-asserted-by":"publisher","first-page":"7971492","DOI":"10.1049\/2023\/7971492","volume":"2023","author":"Y Sun","year":"2023","unstructured":"Sun Y, Bai Y, Liu S, Cui S, Xu P. Thermosensitive micelles gel to deliver quercetin locally for enhanced antibreast cancer efficacy: An in vitro evaluation. IET Nanobiotechnol. 2023;2023:7971492.","journal-title":"IET Nanobiotechnol"},{"key":"3525_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2025.107288","author":"L Wan","year":"2025","unstructured":"Wan L, Wang M, Song Y, Sun G, Zhang R, Chen Z, et al. Multifunctional hydrogel for the treatment of atopic dermatitis: current advances and translational challenges. Eur J Pharm Sci. 2025. https:\/\/doi.org\/10.1016\/j.ejps.2025.107288.","journal-title":"Eur J Pharm Sci"},{"key":"3525_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111352","volume":"118","author":"T Zhang","year":"2021","unstructured":"Zhang T, Chen S, Dou H, Liu Q, Shu G, Lin J, et al. Novel glucosamine-loaded thermosensitive hydrogels based on poloxamers for osteoarthritis therapy by intra-articular injection. Mater Sci Eng C Mater Biol Appl. 2021;118:111352.","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"key":"3525_CR26","doi-asserted-by":"publisher","first-page":"100939","DOI":"10.1016\/j.scp.2022.100939","volume":"31","author":"MM AL-Rajabi","year":"2023","unstructured":"AL-Rajabi MM, Teow YH. Synthesis of thermoresponsive composite hydrogel from Pluronic F127 reinforced by oil palm empty fruit bunches-extracted cellulose for silver sulfadiazine drug delivery. Sustain Chem Pharm. 2023;31:100939.","journal-title":"Sustain Chem Pharm"},{"issue":"10","key":"3525_CR27","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1080\/17425247.2022.2078806","volume":"19","author":"E Lacroce","year":"2022","unstructured":"Lacroce E, Rossi F. Polymer-based thermoresponsive hydrogels for controlled drug delivery. Expert Opin Drug Deliv. 2022;19(10):1203\u201315.","journal-title":"Expert Opin Drug Deliv"},{"issue":"17","key":"3525_CR28","doi-asserted-by":"publisher","DOI":"10.3390\/polym17172350","volume":"17","author":"M Di Martino","year":"2025","unstructured":"Di Martino M, Sessa L, Romano F, Piotto S, Concilio S. Tailored thermoresponsive polyurethane hydrogels: structure\u2013property relationships for injectable biomedical applications. Polymers (Basel). 2025;17(17):2350.","journal-title":"Polymers (Basel)"},{"key":"3525_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2023.106444","volume":"185","author":"F Wang","year":"2023","unstructured":"Wang F, Li Z, Gan X-y, Lu X-l, Jiao B-h, Shen M-h. Quality by design driven development and evaluation of thermosensitive hydrogel loaded with IgY and LL37-SLNs to combat experimental periodontitis. Eur J Pharm Sci. 2023;185:106444.","journal-title":"Eur J Pharm Sci"},{"issue":"4","key":"3525_CR30","doi-asserted-by":"publisher","first-page":"512","DOI":"10.2174\/1567201812666150817122506","volume":"13","author":"C Dalwadi","year":"2016","unstructured":"Dalwadi C, Patel G. Implementation of \u201cquality by design (QbD)\u201d approach for the development of 5-fluorouracil loaded thermosensitive hydrogel. Curr Drug Deliv. 2016;13(4):512\u201327.","journal-title":"Curr Drug Deliv"},{"issue":"5","key":"3525_CR31","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1248\/cpb.57.453","volume":"57","author":"S-H Hsu","year":"2009","unstructured":"Hsu S-H, Leu Y-L, Hu J-W, Fang J-Y. Physicochemical characterization and drug release of thermosensitive hydrogels composed of a hyaluronic acid\/pluronic f127 graft. Chem Pharm Bull (Tokyo). 2009;57(5):453\u20138.","journal-title":"Chem Pharm Bull (Tokyo)"},{"issue":"1","key":"3525_CR32","doi-asserted-by":"publisher","first-page":"44","DOI":"10.3390\/gels8010044","volume":"8","author":"J Garc\u00eda-Couce","year":"2022","unstructured":"Garc\u00eda-Couce J, Tom\u00e1s M, Fuentes G, Que I, Almirall A, Cruz LJ. Chitosan\/Pluronic F127 thermosensitive hydrogel as an injectable dexamethasone delivery carrier. Gels. 2022;8(1):44.","journal-title":"Gels"},{"issue":"22","key":"3525_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/polym14225011","volume":"14","author":"A Pintea","year":"2022","unstructured":"Pintea A, Vlad R-A, Antonoaea P, R\u00e9dai EM, Todoran N, Barab\u00e1s E-C, et al. Structural characterization and optimization of a miconazole oral gel. Polymers (Basel). 2022;14(22):5011.","journal-title":"Polymers (Basel)"},{"issue":"5","key":"3525_CR34","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.3390\/pharmaceutics14051038","volume":"14","author":"F Ferrara","year":"2022","unstructured":"Ferrara F, Benedusi M, Sguizzato M, Cortesi R, Baldisserotto A, Buzzi R, et al. Ethosomes and transethosomes as cutaneous delivery systems for quercetin: a preliminary study on melanoma cells. Pharmaceutics. 2022;14(5):1038.","journal-title":"Pharmaceutics"},{"issue":"2","key":"3525_CR35","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3390\/pharmaceutics12020152","volume":"12","author":"R Neupane","year":"2020","unstructured":"Neupane R, Boddu SH, Renukuntla J, Babu RJ, Tiwari AK. Alternatives to biological skin in permeation studies: current trends and possibilities. Pharmaceutics. 2020;12(2):152.","journal-title":"Pharmaceutics"},{"issue":"2","key":"3525_CR36","doi-asserted-by":"publisher","first-page":"657","DOI":"10.3390\/ijms22020657","volume":"22","author":"J-h Hwang","year":"2021","unstructured":"Hwang J-h, Jeong H, Lee N, Hur S, Lee N, Han JJ, et al. Ex vivo live full-thickness porcine skin model as a versatile in vitro testing method for skin barrier research. Int J Mol Sci. 2021;22(2):657.","journal-title":"Int J Mol Sci"},{"issue":"4","key":"3525_CR37","doi-asserted-by":"publisher","first-page":"261","DOI":"10.4274\/tjps.galenos.2022.60687","volume":"20","author":"F Shiehzadeh","year":"2023","unstructured":"Shiehzadeh F, Mohebi D, Chavoshian O, Daneshmand S. Formulation, characterization, and optimization of a topical gel containing tranexamic acid to prevent superficial bleeding: in vivo and in vitro evaluations. Turkish J Pharm Sci. 2023;20(4):261.","journal-title":"Turkish J Pharm Sci"},{"issue":"3","key":"3525_CR38","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3390\/ph18030337","volume":"18","author":"V Paganini","year":"2025","unstructured":"Paganini V, Monti D, Chetoni P, Burgalassi S, Cesari A, Bellina F, et al. Nanostructured strategies for melanoma treatment\u2014part II: targeted topical delivery of curcumin via poloxamer-based thermosensitive hydrogels. Pharmaceuticals (Basel). 2025;18(3):337.","journal-title":"Pharmaceuticals (Basel)"},{"issue":"1","key":"3525_CR39","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1093\/jaoac\/94.1.100","volume":"94","author":"PM D\u2019Mello","year":"2011","unstructured":"D\u2019Mello PM, Joshi UJ, Shetgiri PP, Dasgupta TK, Darji KK. A simple HPLC method for quantitation of quercetin in herbal extracts. J AOAC Int. 2011;94(1):100\u20135.","journal-title":"J AOAC Int"},{"key":"3525_CR40","doi-asserted-by":"crossref","unstructured":"Abdul AL-Abbas AAH, Mlaghee SM. Therapeutic effect of curcumin on dermatitis induced by acetone in female rats. Kufa J Vet Med Sci. 2023;14(2).","DOI":"10.36326\/kjvs\/2023\/v14i212138"},{"key":"3525_CR41","unstructured":"Zhao Y, van Hasselt CA, Woo K, Wong Y, Liang C, Leung P. Establishment of a modified intranasally ovalbumin induced animal model of allergic rhinitis. Zhonghua er bi yan hou tou Jing wai ke za zhi= Chinese J Otorhinolaryngol Head Neck Surg. 2005;40(3):176\u201380."},{"issue":"1","key":"3525_CR42","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1186\/s13287-022-02774-7","volume":"13","author":"J Guan","year":"2022","unstructured":"Guan J, Li Y, Lu F, Feng J. Adipose-derived stem cells ameliorate atopic dermatitis by suppressing the IL-17 expression of Th17 cells in an ovalbumin-induced mouse model. Stem Cell Res Ther. 2022;13(1):98.","journal-title":"Stem Cell Res Ther"},{"key":"3525_CR43","doi-asserted-by":"publisher","first-page":"1296138","DOI":"10.3389\/fvets.2024.1296138","volume":"11","author":"H-Y Shin","year":"2024","unstructured":"Shin H-Y, Jin HJ, Tae H-J, Oh H-G, Hwang JH. Establishment of an experimental model of ovalbumin-induced atopic dermatitis in canines. Front Vet Sci. 2024;11:1296138.","journal-title":"Front Vet Sci"},{"issue":"1","key":"3525_CR44","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3390\/biom10010057","volume":"10","author":"S Lee","year":"2019","unstructured":"Lee S, Jegal H, Bong S-K, Yoon K-N, Park N-J, Shin M-S, et al. Anti-atopic effect of acorn shell extract on atopic dermatitis-like lesions in mice and its active phytochemicals. Biomolecules. 2019;10(1):57.","journal-title":"Biomolecules"},{"issue":"6","key":"3525_CR45","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.3390\/ijms20061428","volume":"20","author":"MC Kang","year":"2019","unstructured":"Kang MC, Cho K, Lee JH, Subedi L, Yumnam S, Kim SY. Effect of resveratrol-enriched rice on skin inflammation and pruritus in the NC\/Nga mouse model of atopic dermatitis. Int J Mol Sci. 2019;20(6):1428.","journal-title":"Int J Mol Sci"},{"key":"3525_CR46","doi-asserted-by":"publisher","first-page":"113108","DOI":"10.1016\/j.lwt.2022.113108","volume":"157","author":"D Thakur","year":"2022","unstructured":"Thakur D, Singh A, Prabhakar PK, Meghwal M, Upadhyay A. Optimization and characterization of soybean oil-carnauba wax oleogel. LWT-Food Sci Technol. 2022;157:113108.","journal-title":"LWT-Food Sci Technol"},{"key":"3525_CR47","doi-asserted-by":"crossref","unstructured":"Singh N, Pandey SP, Yadav S, Agrawal N, Kumar G, Siddiqui NP, et al. Formulation and Evaluation of an Enoxaparin Aqueous Spray for the Treatment of Contusions by Topical Application. Drug Development and Industrial Pharmacy. 2026(just-accepted):1\u201317.","DOI":"10.1080\/03639045.2026.2617409"},{"issue":"1","key":"3525_CR48","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-48254-6","volume":"9","author":"S Chatterjee","year":"2019","unstructured":"Chatterjee S, Hui P-l, Kan C-w, Wang W. Dual-responsive (pH\/temperature) pluronic F-127 hydrogel drug delivery system for textile-based transdermal therapy. Sci Rep. 2019;9(1):11658.","journal-title":"Sci Rep"},{"issue":"4","key":"3525_CR49","doi-asserted-by":"publisher","first-page":"2400341","DOI":"10.1002\/mame.202400341","volume":"310","author":"A Lupu","year":"2025","unstructured":"Lupu A, Bercea M, Avadanei M, Gradinaru LM, Nita LE, Gradinaru VR. Temperature sensitive pluronic F127\u2010based gels incorporating natural therapeutic agents. Macromol Mater Eng. 2025;310(4):2400341.","journal-title":"Macromol Mater Eng"},{"key":"3525_CR50","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.ejpb.2023.01.007","volume":"184","author":"OM Kolawole","year":"2023","unstructured":"Kolawole OM, Cook MT. In situ gelling drug delivery systems for topical drug delivery. Eur J Pharm Biopharm. 2023;184:36\u201349.","journal-title":"Eur J Pharm Biopharm"},{"issue":"5","key":"3525_CR51","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1208\/s12249-024-02831-9","volume":"25","author":"D Y\u0131lmaz Usta","year":"2024","unstructured":"Y\u0131lmaz Usta D, Teksin ZS, Tugcu-Demiroz F. Evaluation of emulgel and nanostructured lipid carrier-based gel formulations for transdermal administration of ibuprofen: Characterization, mechanical properties, and ex-vivo skin permeation. AAPS PharmSciTech. 2024;25(5):124.","journal-title":"AAPS PharmSciTech"},{"issue":"12","key":"3525_CR52","doi-asserted-by":"publisher","first-page":"2775","DOI":"10.3390\/pharmaceutics14122775","volume":"14","author":"MS Rocha","year":"2022","unstructured":"Rocha MS, Batista JV, Melo MN, Campos VEd, Toledo ALM, Oliveira AP, et al. Pluronic\u00ae F127 thermoresponsive Viscum album hydrogel: physicochemical features and cellular in vitro evaluation. Pharmaceutics. 2022;14(12):2775.","journal-title":"Pharmaceutics"},{"issue":"5","key":"3525_CR53","doi-asserted-by":"publisher","first-page":"376","DOI":"10.3390\/gels9050376","volume":"9","author":"A Lupu","year":"2023","unstructured":"Lupu A, Gradinaru LM, Gradinaru VR, Bercea M. Diversity of bioinspired hydrogels: from structure to applications. Gels. 2023;9(5):376.","journal-title":"Gels"},{"issue":"3","key":"3525_CR54","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.abd.2019.11.007","volume":"95","author":"SW Goh","year":"2020","unstructured":"Goh SW, Jamil A, Safian N, Nor NM, Muhammad N, Saharudin NL. A randomized half-body, double blind, controlled trial on the effects of a pH-modified moisturizer vs. standard moisturizer in mild to moderate atopic dermatitis. An Bras Dermatol. 2020;95(3):320\u20135.","journal-title":"An Bras Dermatol"},{"issue":"1","key":"3525_CR55","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-68732-6","volume":"10","author":"S Das","year":"2020","unstructured":"Das S, Wong AB. Stabilization of ferulic acid in topical gel formulation via nanoencapsulation and pH optimization. Sci Rep. 2020;10(1):12288.","journal-title":"Sci Rep"},{"issue":"5","key":"3525_CR56","first-page":"2249","volume":"8","author":"S Dineshmohan","year":"2018","unstructured":"Dineshmohan S, Gupta VRM. Formulation and characterization of fluconazole as topical gel by porous microparticle based drug delivery system. AJPR. 2018;8(5):2249\u20133387.","journal-title":"AJPR"},{"key":"3525_CR57","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2021.117779","volume":"260","author":"SA Siboro","year":"2021","unstructured":"Siboro SA, Anugrah DS, Ramesh K, Park S-H, Kim H-R, Lim KT. Tunable porosity of covalently crosslinked alginate-based hydrogels and its significance in drug release behavior. Carbohydr Polym. 2021;260:117779.","journal-title":"Carbohydr Polym"},{"key":"3525_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2024.106843","volume":"200","author":"F Firoz","year":"2024","unstructured":"Firoz F, Yousef T, Asser Y, Thaer RM, Sammour RM. Thermo-activated in situ rectal gel preparation for ibuprofen using eutectic mixture. Eur J Pharm Sci. 2024;200:106843.","journal-title":"Eur J Pharm Sci"},{"issue":"1","key":"3525_CR59","doi-asserted-by":"publisher","first-page":"360","DOI":"10.12991\/jrespharm.1634634","volume":"29","author":"M \u00d6zsoy","year":"2025","unstructured":"\u00d6zsoy M, Heidarnejad M. Manufacture, characterization and in vitro drug release studies of chitosan-PVA-MNPs hydrogel essenced drug delivery system for anticancer drug quercetin. J Res Pharm. 2025;29(1):360\u20139.","journal-title":"J Res Pharm"},{"issue":"7","key":"3525_CR60","doi-asserted-by":"publisher","first-page":"679","DOI":"10.3390\/ph14070679","volume":"14","author":"C Chittasupho","year":"2021","unstructured":"Chittasupho C, Junmahasathien T, Chalermmongkol J, Wongjirasakul R, Leesawat P, Okonogi S. Suppression of intracellular reactive oxygen species in human corneal epithelial cells via the combination of quercetin nanoparticles and epigallocatechin gallate and in situ thermosensitive gel formulation for ocular drug delivery. Pharmaceuticals (Basel). 2021;14(7):679.","journal-title":"Pharmaceuticals (Basel)"},{"key":"3525_CR61","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Couce J, Tom\u00e1s M, Fuentes G, Que I, Almirall A, Cruz L. Chitosan\/Pluronic F127 thermosensitive hydrogel as an injectable dexamethasone delivery carrier. Gels. 2022; 8: 44. s Note: MDPI stays neutral with regard to jurisdictional claims in published\u00a0\u2026; 2022","DOI":"10.3390\/gels8010044"},{"issue":"12","key":"3525_CR62","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13122100","volume":"13","author":"L Castillo-Henr\u00edquez","year":"2021","unstructured":"Castillo-Henr\u00edquez L, Sanabria-Espinoza P, Murillo-Castillo B, Montes de Oca-V\u00e1squez G, Batista-Menezes D, Calvo-Guzm\u00e1n B, et al. Topical chitosan-based thermo-responsive scaffold provides dexketoprofen trometamol controlled release for 24 h use. Pharmaceutics. 2021;13(12):2100.","journal-title":"Pharmaceutics"},{"issue":"3","key":"3525_CR63","doi-asserted-by":"publisher","first-page":"198","DOI":"10.3390\/gels9030198","volume":"9","author":"Y Wang","year":"2023","unstructured":"Wang Y, Yue Y, Jia R, Liu X, Cheng Z, Cheng Y, et al. Design and evaluation of paeonol-loaded liposomes in thermoreversible gels for atopic dermatitis. Gels. 2023;9(3):198.","journal-title":"Gels"},{"issue":"5","key":"3525_CR64","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1080\/01932691.2023.2188923","volume":"45","author":"M Kumar","year":"2024","unstructured":"Kumar M, Sharma A, Mahmood S, Thakur A, Mirza MA, Bhatia A. Franz diffusion cell and its implication in skin permeation studies. J Dispers Sci Technol. 2024;45(5):943\u201356.","journal-title":"J Dispers Sci Technol"},{"issue":"9","key":"3525_CR65","doi-asserted-by":"publisher","DOI":"10.3390\/polym12091974","volume":"12","author":"JC Quintanilla de St\u00e9fano","year":"2020","unstructured":"Quintanilla de St\u00e9fano JC, Abundis-Correa V, Herrera-Flores SD, Alvarez AJ. PH-sensitive starch-based hydrogels: synthesis and effect of molecular components on drug release behavior. Polymers (Basel). 2020;12(9):1974.","journal-title":"Polymers (Basel)"},{"issue":"4","key":"3525_CR66","doi-asserted-by":"publisher","first-page":"303","DOI":"10.3390\/gels9040303","volume":"9","author":"R Kharwade","year":"2023","unstructured":"Kharwade R, Ali N, Gangane P, Pawar K, More S, Iqbal M, et al. DOE-assisted formulation, optimization, and characterization of tioconazole-loaded transferosomal hydrogel for the effective treatment of atopic dermatitis: in vitro and in vivo evaluation. Gels. 2023;9(4):303.","journal-title":"Gels"},{"issue":"3\u20132014","key":"3525_CR67","first-page":"358","volume":"5","author":"PN Kendre","year":"2014","unstructured":"Kendre PN, Pande VV, Chavan KM. Novel formulation strategy to enhance solubility of quercetin. Pharmacophore. 2014;5(3\u20132014):358\u201370.","journal-title":"Pharmacophore"},{"key":"3525_CR68","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01006","volume":"10","author":"AA Vigato","year":"2019","unstructured":"Vigato AA, Querobino SM, De Faria NC, Candido ACBB, Magalh\u00e3es LG, Cereda CMS, et al. Physico-chemical characterization and biopharmaceutical evaluation of lipid-poloxamer-based organogels for curcumin skin delivery. Front Pharmacol. 2019;10:1006.","journal-title":"Front Pharmacol"},{"issue":"14","key":"3525_CR69","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25147676","volume":"25","author":"X Chen","year":"2024","unstructured":"Chen X, Wu Y, Jia R, Fang Y, Cao K, Yang X, et al. Antioxidant activity and the therapeutic effect of sinomenine hydrochloride-loaded liposomes-in-hydrogel on atopic dermatitis. Int J Mol Sci. 2024;25(14):7676.","journal-title":"Int J Mol Sci"},{"key":"3525_CR70","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.carbpol.2018.06.023","volume":"197","author":"F Zhuo","year":"2018","unstructured":"Zhuo F, Abourehab MA, Hussain Z. Hyaluronic acid decorated tacrolimus-loaded nanoparticles: efficient approach to maximize dermal targeting and anti-dermatitis efficacy. Carbohydr Polym. 2018;197:478\u201389.","journal-title":"Carbohydr Polym"},{"issue":"1","key":"3525_CR71","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1080\/20415990.2026.2629203","volume":"17","author":"RS Pandey","year":"2026","unstructured":"Pandey RS, Garhewal M, Kumar G, Pandey SP, Agrawal N, Yadav S, et al. Development and optimization of sulfasalazine loaded microemulsion for improved topical treatment of psoriasis. Ther Deliv. 2026;17(1):9\u201326.","journal-title":"Ther Deliv"},{"issue":"1","key":"3525_CR72","doi-asserted-by":"publisher","DOI":"10.1186\/s43556-025-00313-3","volume":"6","author":"R Bai","year":"2025","unstructured":"Bai R, Zheng Y, Dai X. Atopic dermatitis: diagnosis, molecular pathogenesis, and therapeutics. Mol Biomed. 2025;6(1):71.","journal-title":"Mol Biomed"},{"issue":"6","key":"3525_CR73","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1016\/j.jaci.2023.08.030","volume":"152","author":"DK Chu","year":"2023","unstructured":"Chu DK, Chu AW, Rayner DG, Guyatt GH, Yepes-Nunez JJ, Gomez-Escobar L, et al. Topical treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials. J Allergy Clin Immunol. 2023;152(6):1493\u2013519.","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"3525_CR74","doi-asserted-by":"publisher","first-page":"592","DOI":"10.18433\/J3HW2B","volume":"15","author":"H Almeida","year":"2012","unstructured":"Almeida H, Amaral MH, Lob\u00e3o P, Lobo JMS. Pluronic\u00ae F-127 and pluronic lecithin organogel (PLO): main features and their applications in topical and transdermal administration of drugs. J Pharm Pharm Sci. 2012;15(4):592\u2013605.","journal-title":"J Pharm Pharm Sci"},{"key":"3525_CR75","doi-asserted-by":"crossref","unstructured":"Derakhshandeh K, Fashi M, Seifoleslami S. Thermosensitive Pluronic\u00ae hydrogel: prolonged injectable formulation for drug abuse. Drug Design, Dev Ther. 2010:255\u201362.","DOI":"10.2147\/DDDT.S13289"},{"issue":"1","key":"3525_CR76","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1122\/1.5054598","volume":"63","author":"CC Hopkins","year":"2019","unstructured":"Hopkins CC, de Bruyn JR. Gelation and long-time relaxation of aqueous solutions of Pluronic F127. J Rheol. 2019;63(1):191\u2013201.","journal-title":"J Rheol"},{"key":"3525_CR77","doi-asserted-by":"publisher","DOI":"10.1002\/mame.202400457","author":"M Blanco\u2010L\u00f3pez","year":"2025","unstructured":"Blanco\u2010L\u00f3pez M, de Dios\u2010P\u00e9rez I, Gonz\u00e1lez\u2010Garcinu\u00f1o \u00c1, Tabernero A, Mart\u00edn del Valle E. Innovative thermosensitive composite materials: merging Poloxamer PF\u2010127 and polysaccharides for enhanced functional properties. Macromol Mater Eng. 2025. https:\/\/doi.org\/10.1002\/mame.202400457.","journal-title":"Macromol Mater Eng"},{"issue":"1\u20132","key":"3525_CR78","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.ijpharm.2011.05.060","volume":"415","author":"C-C Chen","year":"2011","unstructured":"Chen C-C, Fang C-L, Al-Suwayeh SA, Leu Y-L, Fang J-Y. Transdermal delivery of selegiline from alginate\u2013Pluronic composite thermogels. Int J Pharm. 2011;415(1\u20132):119\u201328.","journal-title":"Int J Pharm"},{"key":"3525_CR79","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.124210","volume":"658","author":"AZM Badruddoza","year":"2024","unstructured":"Badruddoza AZM, Zahid MI, Walsh T, Shah J, Gates D, Yeoh T, et al. Topical drug delivery by Sepineo P600 emulgel: relationship between rheology, physical stability, and formulation performance. Int J Pharm. 2024;658:124210.","journal-title":"Int J Pharm"},{"key":"3525_CR80","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2023.105000","volume":"89","author":"R Smith","year":"2023","unstructured":"Smith R, Brogden N, Fiegel J. Sprayable ciprofloxacin-loaded poloxamer hydrogels for wound infection treatment. J Drug Deliv Sci Technol. 2023;89:105000.","journal-title":"J Drug Deliv Sci Technol"},{"key":"3525_CR81","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.ejpb.2021.10.001","volume":"169","author":"H Braet","year":"2021","unstructured":"Braet H, Rahimi-Gorji M, Debbaut C, Ghorbaniasl G, Van Walleghem T, Cornelis S, et al. Exploring high pressure nebulization of Pluronic F127 hydrogels for intraperitoneal drug delivery. Eur J Pharm Biopharm. 2021;169:134\u201343.","journal-title":"Eur J Pharm Biopharm"},{"issue":"1\u20132","key":"3525_CR82","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.ijpharm.2010.05.012","volume":"394","author":"T Ur-Rehman","year":"2010","unstructured":"Ur-Rehman T, Tavelin S, Gr\u00f6bner G. Effect of DMSO on micellization, gelation and drug release profile of Poloxamer 407. Int J Pharm. 2010;394(1\u20132):92\u20138.","journal-title":"Int J Pharm"},{"issue":"1","key":"3525_CR83","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1186\/1556-276X-9-684","volume":"9","author":"L Dian","year":"2014","unstructured":"Dian L, Yu E, Chen X, Wen X, Zhang Z, Qin L, et al. Enhancing oral bioavailability of quercetin using novel soluplus polymeric micelles. Nanoscale Res Lett. 2014;9(1):684.","journal-title":"Nanoscale Res Lett"},{"key":"3525_CR84","doi-asserted-by":"publisher","first-page":"966750","DOI":"10.3389\/fnut.2022.966750","volume":"9","author":"Y Zhang","year":"2022","unstructured":"Zhang Y, Hou R, Zhu B, Yin G, Zhang J, Zhao W, et al. Changes on the conformational and functional properties of soybean protein isolate induced by quercetin. Front Nutr. 2022;9:966750.","journal-title":"Front Nutr"},{"issue":"8","key":"3525_CR85","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1007\/s00396-023-05109-x","volume":"301","author":"D Patel","year":"2023","unstructured":"Patel D, Gawali SL, Kuperkar K, Hassan PA, Bahadur P. Co-micellization conduct and structural dynamics of block copolymers in water and salt solution environment for drug solubilization enhancement. Colloid Polym Sci. 2023;301(8):919\u201331.","journal-title":"Colloid Polym Sci"},{"key":"3525_CR86","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111643","volume":"119","author":"JB da Silva","year":"2021","unstructured":"da Silva JB, Dos Santos RS, da Silva MB, Braga G, Cook MT, Bruschi ML. Interaction between mucoadhesive cellulose derivatives and Pluronic F127: investigation on the micelle structure and mucoadhesive performance. Mater Sci Eng C Mater Biol Appl. 2021;119:111643.","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"issue":"9","key":"3525_CR87","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.3390\/polym14091836","volume":"14","author":"N Hirun","year":"2022","unstructured":"Hirun N, Kraisit P, Tantishaiyakul V. Thermosensitive polymer blend composed of poloxamer 407, poloxamer 188 and polycarbophil for the use as mucoadhesive in situ gel. Polymers (Basel). 2022;14(9):1836.","journal-title":"Polymers (Basel)"},{"issue":"4","key":"3525_CR88","doi-asserted-by":"publisher","first-page":"256","DOI":"10.3390\/gels10040256","volume":"10","author":"JY Lee","year":"2024","unstructured":"Lee JY, Shin HH, Cho C, Ryu JH. Effect of tannic acid concentrations on temperature-sensitive sol\u2013gel transition and stability of tannic acid\/Pluronic F127 composite hydrogels. Gels. 2024;10(4):256.","journal-title":"Gels"},{"issue":"6","key":"3525_CR89","doi-asserted-by":"publisher","DOI":"10.1016\/j.jscs.2022.101541","volume":"26","author":"A Ashames","year":"2022","unstructured":"Ashames A, Pervaiz F, Al-Tabakha M, Khalid K, Hassan N, Shoukat H, et al. Synthesis of cross-linked carboxymethyl cellulose and poly (2-acrylamido-2-methylpropane sulfonic acid) hydrogel for sustained drug release optimized by Box-Behnken design. J Saudi Chem Soc. 2022;26(6):101541.","journal-title":"J Saudi Chem Soc"},{"issue":"10","key":"3525_CR90","first-page":"e94120","volume":"17","author":"AD Parga","year":"2025","unstructured":"Parga AD, Doshi N, Bhat RM, Vu T, Sraa K, Casagrande S, et al. Transdermal drug delivery systems in atopic dermatitis: a review of vehicle innovation and skin barrier challenges. Cureus. 2025;17(10):e94120.","journal-title":"Cureus"},{"key":"3525_CR91","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2025.102517","author":"Y Kim","year":"2025","unstructured":"Kim Y, Park K, Kim MS. Recent advances in polymer-based drug delivery systems for atopic dermatitis: enhancing therapeutic efficacy and outcomes. Mater Today Bio. 2025. https:\/\/doi.org\/10.1016\/j.mtbio.2025.102517.","journal-title":"Mater Today Bio"},{"key":"3525_CR92","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ijbiomac.2021.03.146","volume":"182","author":"A Samadi","year":"2021","unstructured":"Samadi A, Pourmadadi M, Yazdian F, Rashedi H, Navaei-Nigjeh M. Ameliorating quercetin constraints in cancer therapy with pH-responsive agarose-polyvinylpyrrolidone-hydroxyapatite nanocomposite encapsulated in double nanoemulsion. Int J Biol Macromol. 2021;182:11\u201325.","journal-title":"Int J Biol Macromol"},{"key":"3525_CR93","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2025.145183","volume":"318","author":"W Inthanusorn","year":"2025","unstructured":"Inthanusorn W, Boonthip C, Paenkaew S, Wichai U, Channei D, Rutnakornpituk B, et al. Highly flexible thermoresponsive alginate-containing hydrogels: curcuminoid encapsulation and its release kinetics and mechanism. Int J Biol Macromol. 2025;318:145183.","journal-title":"Int J Biol Macromol"},{"key":"3525_CR94","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.jcis.2023.03.013","volume":"641","author":"A-S Huysecom","year":"2023","unstructured":"Huysecom A-S, Glorieux C, Thoen J, Thielemans W, Fustin C-A, Moldenaers P, et al. Phase behavior of medium-length hydrophobically associating PEO-PPO multiblock copolymers in aqueous media. J Colloid Interface Sci. 2023;641:521\u201338.","journal-title":"J Colloid Interface Sci"},{"issue":"12","key":"3525_CR95","doi-asserted-by":"publisher","first-page":"671","DOI":"10.3390\/pharmaceutics11120671","volume":"11","author":"E Russo","year":"2019","unstructured":"Russo E, Villa C. Poloxamer hydrogels for biomedical applications. Pharmaceutics. 2019;11(12):671.","journal-title":"Pharmaceutics"},{"key":"3525_CR96","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14102137","author":"MA T\u0103nase","year":"2022","unstructured":"T\u0103nase MA, Soare AC, Di\u0163u LM, Nistor CL, Mihaescu CI, Gifu IC, et al. Influence of the hydrophobicity of pluronic micelles encapsulating curcumin on the membrane permeability and enhancement of photoinduced antibacterial activity. Pharmaceutics. 2022. https:\/\/doi.org\/10.3390\/pharmaceutics14102137.","journal-title":"Pharmaceutics"},{"key":"3525_CR97","doi-asserted-by":"publisher","DOI":"10.3390\/ijms27031300","author":"KP Quezada","year":"2026","unstructured":"Quezada KP, Gonz\u00e1lez-Gaitano G, Nguewa P. Pluronic(\u00ae) F127 polymeric micelles as nanocarriers for pentamidine: improving safety and biological efficacy against Leishmania major. Int J Mol Sci. 2026. https:\/\/doi.org\/10.3390\/ijms27031300.","journal-title":"Int J Mol Sci"},{"key":"3525_CR98","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.121322","volume":"611","author":"K McLean","year":"2022","unstructured":"McLean K, Zhan W. Mathematical modelling of nanoparticle-mediated topical drug delivery to skin tissue. Int J Pharm. 2022;611:121322.","journal-title":"Int J Pharm"},{"issue":"3","key":"3525_CR99","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1021\/acs.molpharmaceut.4c01058","volume":"22","author":"MdS Brighenti","year":"2025","unstructured":"Brighenti MdS, Montanheri LRdS, Duque MD, Andreo-Filho N, Lopes PS, Garcia MTJ, et al. In vitro drug release and ex vivo dermal drug permeation studies of selected commercial benzoyl peroxide topical formulations: correlation between human and porcine skin models. Mol Pharm. 2025;22(3):1365\u201372.","journal-title":"Mol Pharm"},{"key":"3525_CR100","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/B978-0-323-89868-3.00016-1","volume-title":"Polymeric micelles for drug delivery","author":"M Zaman","year":"2022","unstructured":"Zaman M, Khan R, Khan A, Talat M, Aman W, Farooq U. Dual-responsive polymeric micelles for drug delivery. In: Polymeric micelles for drug delivery. Elsevier; 2022. p. 429\u201347."},{"issue":"8","key":"3525_CR101","doi-asserted-by":"publisher","first-page":"4130","DOI":"10.3390\/ijms22084130","volume":"22","author":"J Sroka-Tomaszewska","year":"2021","unstructured":"Sroka-Tomaszewska J, Trzeciak M. Molecular mechanisms of atopic dermatitis pathogenesis. Int J Mol Sci. 2021;22(8):4130.","journal-title":"Int J Mol Sci"},{"key":"3525_CR102","doi-asserted-by":"publisher","DOI":"10.2147\/jir.s467327","author":"AR Maskey","year":"2024","unstructured":"Maskey AR, Mo X, Li X-M. Preclinical models of atopic dermatitis suitable for mechanistic and therapeutic investigations. J Inflamm Res. 2024. https:\/\/doi.org\/10.2147\/jir.s467327.","journal-title":"J Inflamm Res"},{"issue":"5","key":"3525_CR103","doi-asserted-by":"publisher","first-page":"2856","DOI":"10.1007\/s10753-025-02236-1","volume":"48","author":"S-C Yang","year":"2025","unstructured":"Yang S-C, Chang Z-Y, Hsiao C-Y, Alshetaili A, Wei S-H, Hsiao Y-T, et al. Topical anti-inflammatory effects of quercetin glycosides on atopic dermatitis-like lesions: influence of the glycone type on efficacy and skin absorption. Inflammation. 2025;48(5):2856\u201373.","journal-title":"Inflammation"}],"container-title":["AAPS PharmSciTech"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1208\/s12249-026-03525-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1208\/s12249-026-03525-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1208\/s12249-026-03525-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:01:41Z","timestamp":1789153301000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1208\/s12249-026-03525-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,11]]},"references-count":103,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["3525"],"URL":"https:\/\/doi.org\/10.1208\/s12249-026-03525-0","relation":{},"ISSN":["1530-9932"],"issn-type":[{"value":"1530-9932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,11]]},"assertion":[{"value":"6 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"291"}}