{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:06:02Z","timestamp":1789826762284,"version":"4.0.1"},"reference-count":44,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T00:00:00Z","timestamp":1585353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100003243","name":"Ministry of Health of the Czech Republic","doi-asserted-by":"publisher","award":["16-30345 A"],"award-info":[{"award-number":["16-30345 A"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"publisher","award":["Q25"],"award-info":[{"award-number":["Q25"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"publisher","award":["Q28"],"award-info":[{"award-number":["Q28"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Institute for Clinical and Experimental Medicine\u2014IKEM","award":["IN 00023001"],"award-info":[{"award-number":["IN 00023001"]}]},{"name":"RVO","award":["VFN64165"],"award-info":[{"award-number":["VFN64165"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Impaired glucose homeostasis is a common finding in pheochromocytoma (PHEO), especially with adrenergic phenotype. The possible contribution of incretin dysfunction to dysglycemia in PHEO patients has not been studied.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To compare changes in pancreatic endocrine function and gut hormones\u2019 production during a liquid meal test before and 1 year after adrenalectomy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a prospective study, we included 18 patients with PHEO (13 females) with adrenergic biochemical phenotype. A liquid meal test with predefined isocaloric enteral nutrition was performed to evaluate dynamic changes in pancreatic hormones and incretins.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>During the meal test, insulin levels were significantly lower before adrenalectomy only in the early phase of insulin secretion, but changes in area under the curve (AUC) did not reach statistical significance (AUC\u2005=\u20050.07). Plasma glucagon (AUC\u2005&amp;lt;\u20050.01) and pancreatic polypeptide levels (AUC\u2005&amp;lt;\u20050.01) were suppressed in comparison with the postoperative state. Impaired response to the meal was found preoperatively for glucagon-like peptide-1 (GLP-1; AUC P\u2005&amp;lt;\u20050.05), but not glucose-dependent insulinotropic polypepide (GIP; AUC P\u2005=\u20050.21). No significant changes in insulin resistance indices were found, except for the homeostatic model assessment-beta index, an indicator of the function of islet \u03b2 cells, which negatively correlated with plasma metanephrine (R\u2005=\u2005\u20130.66, P\u2005&amp;lt;\u20050.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our study shows suppression of pancreatic \u03b1 and \u03b2 cell function and impaired GLP-1 secretion during a dynamic meal test in patients with PHEO, which is improved after its surgical treatment. These data demonstrate a novel and potentially significant interconnection between excessive catecholamine production and the secretion of glucoregulatory hormones.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/clinem\/dgaa154","type":"journal-article","created":{"date-parts":[[2020,3,29]],"date-time":"2020-03-29T10:35:02Z","timestamp":1585478102000},"page":"1878-1887","source":"Crossref","is-referenced-by-count":19,"title":["Pheochromocytoma With Adrenergic Biochemical Phenotype Shows Decreased GLP-1 Secretion and Impaired Glucose Tolerance"],"prefix":"10.1210","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8992-3562","authenticated-orcid":false,"given":"Ond\u0159ej","family":"Petr\u00e1k","sequence":"first","affiliation":[{"name":"Center of Hypertension, Third Department of Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0088-0277","authenticated-orcid":false,"given":"Judita","family":"Kl\u00edmov\u00e1","sequence":"additional","affiliation":[{"name":"Center of Hypertension, Third Department of Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5322-4612","authenticated-orcid":false,"given":"Milo\u0161","family":"Mr\u00e1z","sequence":"additional","affiliation":[{"name":"Center for Experimental Medicine and Diabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic"},{"name":"Institute for Medical Biochemistry and Laboratory Diagnostics, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9425-6944","authenticated-orcid":false,"given":"Denisa","family":"Haluz\u00edkov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Sport Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1092-7312","authenticated-orcid":false,"given":"Radka Petr\u00e1kov\u00e1","family":"Dole\u017ealov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Sport Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8264-3883","authenticated-orcid":false,"given":"Helena","family":"Kratochv\u00edlov\u00e1","sequence":"additional","affiliation":[{"name":"Institute for Medical Biochemistry and Laboratory Diagnostics, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4916-7031","authenticated-orcid":false,"given":"Zde\u0148ka","family":"Lacinov\u00e1","sequence":"additional","affiliation":[{"name":"Institute for Medical Biochemistry and Laboratory Diagnostics, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8907-541X","authenticated-orcid":false,"given":"Kv\u011btoslav","family":"Nov\u00e1k","sequence":"additional","affiliation":[{"name":"Department of Urology, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6000-7683","authenticated-orcid":false,"given":"David","family":"Michalsk\u00fd","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4668-5837","authenticated-orcid":false,"given":"Petr","family":"Waldauf","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University Hospital Kr\u00e1lovsk\u00e9 Vinohrady and Third Faculty of Medicine, Charles University in Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9488-9706","authenticated-orcid":false,"given":"Robert","family":"Holaj","sequence":"additional","affiliation":[{"name":"Center of Hypertension, Third Department of Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8242-9705","authenticated-orcid":false,"suffix":"Jr","given":"Ji\u0159\u00ed","family":"Widimsk\u00fd","sequence":"additional","affiliation":[{"name":"Center of Hypertension, Third Department of Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3395-8373","authenticated-orcid":false,"given":"Tom\u00e1\u0161","family":"Zelinka","sequence":"additional","affiliation":[{"name":"Center of Hypertension, Third Department of Medicine, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0201-6888","authenticated-orcid":false,"given":"Martin","family":"Haluz\u00edk","sequence":"additional","affiliation":[{"name":"Center for Experimental Medicine and Diabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic"},{"name":"Institute for Medical Biochemistry and Laboratory Diagnostics, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2020,3,28]]},"reference":[{"key":"2021122105123544100_CIT0001","article-title":"Pheochromocytoma and paraganglioma.","volume-title":"Endotext","author":"Pacak","year":"2000"},{"issue":"5","key":"2021122105123544100_CIT0002","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1055\/s-0032-1306294","article-title":"High incidence of cardiovascular complications in pheochromocytoma","volume":"44","author":"Zelinka","year":"2012","journal-title":"Horm Metab Res."},{"issue":"11","key":"2021122105123544100_CIT0003","doi-asserted-by":"crossref","first-page":"5170","DOI":"10.1210\/jc.2018-02644","article-title":"Blood pressure profile, catecholamine phenotype, and target organ damage in pheochromocytoma\/paraganglioma","volume":"104","author":"Petr\u00e1k","year":"2019","journal-title":"J Clin Endocrinol Metab."},{"issue":"4","key":"2021122105123544100_CIT0004","first-page":"e4551","article-title":"Glycemic disturbances in pheochromocytoma and paraganglioma","volume":"11","author":"Ronen","year":"2019","journal-title":"Cureus."},{"issue":"9","key":"2021122105123544100_CIT0005","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1097\/00004872-200309000-00020","article-title":"Diabetes as a marker of pheochromocytoma in hypertensive patients","volume":"21","author":"La Batide-Alanore","year":"2003","journal-title":"J Hypertens."},{"issue":"4","key":"2021122105123544100_CIT0006","doi-asserted-by":"crossref","first-page":"423","DOI":"10.3949\/ccjm.59.4.423","article-title":"Diabetic ketoacidosis associated with pheochromocytoma","volume":"59","author":"Edelman","year":"1992","journal-title":"Cleve Clin J Med."},{"issue":"4","key":"2021122105123544100_CIT0007","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1210\/jc.2012-3625","article-title":"Changes in energy metabolism in pheochromocytoma","volume":"98","author":"Petr\u00e1k","year":"2013","journal-title":"J Clin Endocrinol Metab."},{"issue":"1","key":"2021122105123544100_CIT0008","doi-asserted-by":"crossref","first-page":"61","DOI":"10.14310\/horm.2002.1184","article-title":"Insulin resistance in pheochromocytoma improves more by surgical rather than by medical treatment","volume":"2","author":"Diamanti-Kandarakis","year":"2003","journal-title":"Hormones (Athens)."},{"issue":"9","key":"2021122105123544100_CIT0009","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.1210\/jc.2017-00357","article-title":"Insulin secretion and insulin sensitivity before and after surgical treatment of pheochromocytoma or paraganglioma","volume":"102","author":"Komada","year":"2017","journal-title":"J Clin Endocrinol Metab."},{"issue":"8","key":"2021122105123544100_CIT0010","doi-asserted-by":"crossref","first-page":"3632","DOI":"10.1210\/jc.2003-030000","article-title":"Improvement of insulin sensitivity after adrenalectomy in patients with pheochromocytoma","volume":"88","author":"Wiesner","year":"2003","journal-title":"J Clin Endocrinol Metab."},{"issue":"2","key":"2021122105123544100_CIT0011","doi-asserted-by":"crossref","first-page":"251","DOI":"10.7326\/0003-4819-71-2-251","article-title":"Inhibition of insulin secretion by catecholamines in pheochromocytoma","volume":"71","author":"Colwell","year":"1969","journal-title":"Ann Intern Med."},{"issue":"3","key":"2021122105123544100_CIT0012","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1210\/jcem-49-3-322","article-title":"Pancreatic alpha- and beta-cell function in pheochromocytoma","volume":"49","author":"Hamaji","year":"1979","journal-title":"J Clin Endocrinol Metab."},{"issue":"3","key":"2021122105123544100_CIT0013","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1172\/JCI110306","article-title":"Inhibitory effect of epinephrine on insulin-stimulated glucose uptake by rat skeletal muscle","volume":"68","author":"Chiasson","year":"1981","journal-title":"J Clin Invest."},{"issue":"3","key":"2021122105123544100_CIT0014","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1172\/JCI109718","article-title":"Epinephrine-induced insulin resistance in man","volume":"65","author":"Deibert","year":"1980","journal-title":"J Clin Invest."},{"issue":"6","key":"2021122105123544100_CIT0015","first-page":"E616","article-title":"Direct alpha-adrenergic stimulation of hepatic glucose production in human subjects","volume":"245","author":"Rosen","year":"1983","journal-title":"Am J Physiol."},{"issue":"2","key":"2021122105123544100_CIT0016","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1172\/JCI111226","article-title":"Epinephrine supports the postabsorptive plasma glucose concentration and prevents hypoglycemia when glucagon secretion is deficient in man","volume":"73","author":"Rosen","year":"1984","journal-title":"J Clin Invest."},{"issue":"6","key":"2021122105123544100_CIT0017","first-page":"409","article-title":"Beta-adrenoceptors desensitization may modulate catecholamine induced insulin resistance in human pheochromocytoma","volume":"15","author":"di Paolo","year":"1989","journal-title":"Diabete Metab."},{"issue":"4","key":"2021122105123544100_CIT0018","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1210\/endo-114-4-1272","article-title":"Desensitization of beta-adrenergic receptors by pheochromocytoma","volume":"114","author":"Tsujimoto","year":"1984","journal-title":"Endocrinology."},{"issue":"1","key":"2021122105123544100_CIT0019","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1210\/endo-113-1-354","article-title":"Selective down-regulation of adrenergic receptor subtypes in tissues from rats with pheochromocytoma","volume":"113","author":"Snavely","year":"1983","journal-title":"Endocrinology."},{"issue":"1","key":"2021122105123544100_CIT0020","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1172\/JCI109840","article-title":"Epinephrine plasma metabolic clearance rates and physiologic thresholds for metabolic and hemodynamic actions in man","volume":"66","author":"Clutter","year":"1980","journal-title":"J Clin Invest."},{"issue":"12","key":"2021122105123544100_CIT0021","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1007\/s001250051093","article-title":"Induction of rat muscle insulin resistance by epinephrine is accompanied by increased interstitial glucose and lactate concentrations","volume":"41","author":"Niklasson","year":"1998","journal-title":"Diabetologia."},{"issue":"4","key":"2021122105123544100_CIT0022","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1373\/clinchem.2004.045484","article-title":"Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines","volume":"51","author":"Eisenhofer","year":"2005","journal-title":"Clin Chem."},{"issue":"2","key":"2021122105123544100_CIT0023","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1210\/jc.2010-1588","article-title":"Age at diagnosis of pheochromocytoma differs according to catecholamine phenotype and tumor location","volume":"96","author":"Eisenhofer","year":"2011","journal-title":"J Clin Endocrinol Metab."},{"issue":"5","key":"2021122105123544100_CIT0024","doi-asserted-by":"crossref","first-page":"E1223","DOI":"10.1152\/ajpendo.90591.2008","article-title":"Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma","volume":"295","author":"Eisenhofer","year":"2008","journal-title":"Am J Physiol Endocrinol Metab."},{"key":"2021122105123544100_CIT0025","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.2337\/dc18-S002","article-title":"2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2018","volume":"41","author":"American Diabetes Association","year":"2018","journal-title":"Diabetes Care."},{"issue":"1","key":"2021122105123544100_CIT0026","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jada.2008.10.004","article-title":"Assessing validity and reliability of resting metabolic rate in six gas analysis systems","volume":"109","author":"Cooper","year":"2009","journal-title":"J Am Diet Assoc."},{"issue":"3","key":"2021122105123544100_CIT0027","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF03346795","article-title":"Endocrine pancreatic function in pheochromocytoma","volume":"14","author":"Sicolo","year":"1991","journal-title":"J Endocrinol Invest."},{"issue":"2","key":"2021122105123544100_CIT0028","first-page":"275","article-title":"Pheochromocytoma and diabetes mellitus","volume":"19","author":"Lorini","year":"1983","journal-title":"Clin Endocrinol (Oxf)."},{"issue":"10","key":"2021122105123544100_CIT0029","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.2337\/db11-0425","article-title":"Fatty acids, obesity, and insulin resistance: time for a reevaluation","volume":"60","author":"Karpe","year":"2011","journal-title":"Diabetes."},{"issue":"5962","key":"2021122105123544100_CIT0030","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1126\/science.1176827","article-title":"Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes","volume":"327","author":"Rosengren","year":"2010","journal-title":"Science."},{"issue":"7466","key":"2021122105123544100_CIT0031","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0140-6736(66)92986-2","article-title":"Inhibition of insulin secretion by a phaeochromocytoma","volume":"2","author":"Wilber","year":"1966","journal-title":"Lancet."},{"issue":"2","key":"2021122105123544100_CIT0032","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1507\/endocrj.EJ18-0407","article-title":"Differences in the actions of adrenaline and noradrenaline with regard to glucose intolerance in patients with pheochromocytoma","volume":"66","author":"Abe","year":"2019","journal-title":"Endocr J."},{"issue":"2","key":"2021122105123544100_CIT0033","first-page":"177","article-title":"Catecholamines potentiate the effect of thyroid hormone on intestinal absorption of glucose in the rat","volume":"34","author":"Olaleye","year":"2005","journal-title":"Afr J Med Med Sci."},{"issue":"7","key":"2021122105123544100_CIT0034","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1210\/jcem-29-7-911","article-title":"Insulin and glucagon responses in subjects with pheochromocytoma: effect of alpha adrenergic blockade","volume":"29","author":"Vance","year":"1969","journal-title":"J Clin Endocrinol Metab."},{"issue":"2","key":"2021122105123544100_CIT0035","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1210\/jcem-54-2-447","article-title":"Circulating catecholamine and glucagon responses to insulin-induced blood glucose decrement in a patient with pheochromocytoma","volume":"54","author":"Bolli","year":"1982","journal-title":"J Clin Endocrinol Metab."},{"issue":"2","key":"2021122105123544100_CIT0036","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00210-003-0858-5","article-title":"Involvement of alpha1 and beta-adrenoceptors in adrenaline stimulation of the glucagon-secreting mouse alpha-cell","volume":"369","author":"Vieira","year":"2004","journal-title":"Naunyn Schmiedebergs Arch Pharmacol."},{"issue":"3","key":"2021122105123544100_CIT0037","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1210\/en.2011-1979","article-title":"Minireview: Glucagon in stress and energy homeostasis","volume":"153","author":"Jones","year":"2012","journal-title":"Endocrinology."},{"issue":"6","key":"2021122105123544100_CIT0038","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.cmet.2010.04.007","article-title":"GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis","volume":"11","author":"De Marinis","year":"2010","journal-title":"Cell Metab."},{"issue":"7897","key":"2021122105123544100_CIT0039","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0140-6736(75)92375-2","article-title":"The essential role of glucagon in the pathogenesis of diabetes mellitus","volume":"1","author":"Unger","year":"1975","journal-title":"Lancet."},{"issue":"2","key":"2021122105123544100_CIT0040","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/iju.13864","article-title":"Incidence and predictive factors of hypoglycemia after pheochromocytoma resection","volume":"26","author":"Araki","year":"2019","journal-title":"Int J Urol."},{"issue":"6","key":"2021122105123544100_CIT0041","doi-asserted-by":"crossref","first-page":"884","DOI":"10.2337\/dc16-0351","article-title":"Roles of the gut in glucose homeostasis","volume":"39","author":"Holst","year":"2016","journal-title":"Diabetes Care."},{"key":"2021122105123544100_CIT0042","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.molmet.2019.09.010","article-title":"Glucagon-like peptide 1 (GLP-1)","volume":"30","author":"M\u00fcller","year":"2019","journal-title":"Mol Metab."},{"issue":"4","key":"2021122105123544100_CIT0043","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/j.bbrc.2015.03.151","article-title":"Integrative function of adrenaline receptors for glucagon-like peptide-1 exocytosis in enteroendocrine L cell line GLUTag","volume":"460","author":"Harada","year":"2015","journal-title":"Biochem Biophys Res Commun."},{"issue":"5","key":"2021122105123544100_CIT0044","doi-asserted-by":"crossref","first-page":"E939","DOI":"10.1152\/ajpendo.00197.2004","article-title":"Neural regulation of glucagon-like peptide-1 secretion in pigs","volume":"287","author":"Hansen","year":"2004","journal-title":"Am J Physiol Endocrinol Metab."}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgaa154\/32978938\/dgaa154.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/105\/6\/1878\/41829570\/jcem_105_6_1878.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/105\/6\/1878\/41829570\/jcem_105_6_1878.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T05:13:21Z","timestamp":1640063601000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/105\/6\/1878\/5813460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,28]]},"references-count":44,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,3,28]]},"published-print":{"date-parts":[[2020,6,1]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgaa154","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,6]]},"published":{"date-parts":[[2020,3,28]]}}}