{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T22:24:56Z","timestamp":1788387896483,"version":"build-2803163510"},"reference-count":49,"publisher":"The Endocrine Society","issue":"1","license":[{"start":{"date-parts":[[2020,8,20]],"date-time":"2020-08-20T00:00:00Z","timestamp":1597881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Context<\/jats:title><jats:p>Growth retardation is an established complication of anorexia nervosa (AN); however, findings concerning the adult height of AN patients are inconsistent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this work was to assess linear growth and adult height in female adolescents with AN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and Setting<\/jats:title><jats:p>A prospective observational study was conducted in a tertiary university hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Participants included all 255 female adolescent AN patients hospitalized in the pediatric psychosomatic department between January 1, 2000 and May 31, 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Height and weight were assessed at admission and during hospitalization. Patients were subsequently invited for measurement of adult height. Additional data collected included premorbid height data, menstrual history, skeletal age, pertinent laboratory studies, and parental heights.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measure<\/jats:title><jats:p>The main outcome measure of this study was adult height.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age at admission was 15.4\u2005\u00b1\u20051.75 years, mean body mass index (BMI) was 15.7\u2005\u00b1\u20051.8 kg\/m2 (BMI SDS\u2005=\u2005\u20132.3\u2005\u00b1\u20051.45 kg\/m2). Premorbid height SD scores (SDS) were not significantly different from those expected in normal adolescents (0.005\u2005\u00b1\u20050.96). However, height SDS at admission (\u20130.36\u2005\u00b1\u20050.99), discharge (\u20130.34\u2005\u00b1\u20050.96), and at adult height (\u20130.29\u2005\u00b1\u20050.95), were significantly (P\u2005&amp;lt;\u2005.001) lower than expected. Furthermore, adult height was significantly (P\u2005=\u2005.006) shorter compared to the midparental target height. Stepwise forward linear regression analysis identified age (r\u2005=\u20050.32, P\u2005=\u2005.002) and bone age (r\u2005=\u2005\u20130.29, P\u2005=\u2005.006) on admission, linear growth during hospitalization (r\u2005=\u20050.47, P\u2005&amp;lt;\u2005.001), and change in luteinizing hormone during hospitalization (r\u2005=\u2005\u20130.265, P\u2005=\u2005.021) as independent predictors of improvement in height SDS from the time of admission to adult height.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Whereas the premorbid height of female adolescent AN patients is normal, linear growth retardation is a prominent feature of their illness. Weight restoration is associated with catch-up growth, but complete catch-up is often not achieved.<\/jats:p><\/jats:sec>","DOI":"10.1210\/clinem\/dgaa510","type":"journal-article","created":{"date-parts":[[2020,8,20]],"date-time":"2020-08-20T13:15:30Z","timestamp":1597929330000},"page":"e1-e10","source":"Crossref","is-referenced-by-count":27,"title":["Prospective Longitudinal Assessment of Linear Growth and Adult Height in Female Adolescents With Anorexia Nervosa"],"prefix":"10.1210","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6129-5154","authenticated-orcid":false,"given":"Dalit","family":"Modan-Moses","sequence":"first","affiliation":[{"name":"Pediatric Endocrinology and Diabetes Unit, The Edmond and Lily Safra Children\u2019s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel"},{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Yaroslavsky","sequence":"additional","affiliation":[{"name":"Pediatric Psychosomatic Department, Division of Child and Adolescent Psychiatry, The Edmond and Lily Safra Children\u2019s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orit","family":"Pinhas-Hamiel","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology and Diabetes Unit, The Edmond and Lily Safra Children\u2019s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel"},{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Levy-Shraga","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology and Diabetes Unit, The Edmond and Lily Safra Children\u2019s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel"},{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Kochavi","sequence":"additional","affiliation":[{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Iron-Segev","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry, Food Science and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel"},{"name":"School of Nutrition, Peres Academic Center, Rehovot, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adi","family":"Enoch-Levy","sequence":"additional","affiliation":[{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Toledano","sequence":"additional","affiliation":[{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Stein","sequence":"additional","affiliation":[{"name":"Pediatric Psychosomatic Department, Division of Child and Adolescent Psychiatry, The Edmond and Lily Safra Children\u2019s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel"},{"name":"The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2020,8,20]]},"reference":[{"issue":"1","key":"2021122204023621200_CIT0001","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/000992288602500101","article-title":"Effect of anorexia nervosa on linear growth","volume":"25","author":"Pfeiffer","year":"1986","journal-title":"Clin Pediatr (Phila)."},{"issue":"1","key":"2021122204023621200_CIT0002","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0016-5085(81)90183-9","article-title":"Reversal of growth retardation in Crohn\u2019s disease with therapy emphasizing oral nutritional restitution","volume":"80","author":"Kirschner","year":"1981","journal-title":"Gastroenterology."},{"key":"2021122204023621200_CIT0003","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/S0022-3476(63)80035-9","article-title":"Catch-up growth following illness or starvation. An example of developmental canalization in man","volume":"62","author":"Prader","year":"1963","journal-title":"J Pediatr."},{"issue":"7","key":"2021122204023621200_CIT0004","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1007\/s004670000338","article-title":"Catch-up growth: possible mechanisms","volume":"14","author":"Gafni","year":"2000","journal-title":"Pediatr Nephrol."},{"key":"2021122204023621200_CIT0005","first-page":"73","article-title":"Effects of nutrition and disease on human growth","volume":"3","author":"Acheson","year":"1963","journal-title":"Symp Soc Human Biol."},{"key":"2021122204023621200_CIT0006","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jpsychires.2016.03.003","article-title":"The DSM-5 diagnostic criteria for anorexia nervosa may change its population prevalence and prognostic value","volume":"77","author":"Mustelin","year":"2016","journal-title":"J Psychiatr Res."},{"key":"2021122204023621200_CIT0007","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s40337-017-0186-7","article-title":"Feeding and eating disorders in the DSM-5 era: a systematic review of prevalence rates in non-clinical male and female samples","volume":"5","author":"Lindvall Dahlgren","year":"2017","journal-title":"J Eat Disord."},{"key":"2021122204023621200_CIT0008","article-title":"DSM-5 Task Force","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-5.","author":"American Psychiatric Association","year":"2013","edition":"5th ed"},{"issue":"1","key":"2021122204023621200_CIT0009","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0197-0070(83)80224-1","article-title":"Anorexia nervosa presenting as growth retardation in adolescents","volume":"4","author":"Root","year":"1983","journal-title":"J Adolesc Health Care."},{"issue":"8","key":"2021122204023621200_CIT0010","first-page":"581","article-title":"Stunting of growth in anorexia nervosa during the prepubertal and pubertal period","volume":"30","author":"Danziger","year":"1994","journal-title":"Isr J Med Sci."},{"issue":"6","key":"2021122204023621200_CIT0011","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/1054-139X(94)00003-W","article-title":"Medical complications in male adolescents with anorexia nervosa","volume":"16","author":"Siegel","year":"1995","journal-title":"J Adolesc Health."},{"issue":"2","key":"2021122204023621200_CIT0012","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1054-139X(02)00342-7","article-title":"Reversibility of growth stunting in early onset anorexia nervosa: a prospective study","volume":"31","author":"Lantzouni","year":"2002","journal-title":"J Adolesc Health."},{"issue":"4","key":"2021122204023621200_CIT0013","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1002\/eat.20182","article-title":"Weight requirements for catch-up growth in girls with eating disorders and onset of weight loss before menarche","volume":"38","author":"Swenne","year":"2005","journal-title":"Int J Eat Disord."},{"issue":"6","key":"2021122204023621200_CIT0014","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/eat.20409","article-title":"Association between low height and eating disorders: cause or effect?","volume":"40","author":"Favaro","year":"2007","journal-title":"Int J Eat Disord."},{"issue":"6","key":"2021122204023621200_CIT0015","doi-asserted-by":"crossref","first-page":"e1517","DOI":"10.1542\/peds.2007-2820","article-title":"Determinants of height in adolescent girls with anorexia nervosa","volume":"121","author":"Prabhakaran","year":"2008","journal-title":"Pediatrics."},{"issue":"2","key":"2021122204023621200_CIT0016","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1542\/peds.111.2.270","article-title":"Stunting of growth as a major feature of anorexia nervosa in male adolescents","volume":"111","author":"Modan-Moses","year":"2003","journal-title":"Pediatrics."},{"issue":"9","key":"2021122204023621200_CIT0017","doi-asserted-by":"crossref","first-page":"e45504","DOI":"10.1371\/journal.pone.0045504","article-title":"Linear growth and final height characteristics in adolescent females with anorexia nervosa","volume":"7","author":"Modan-Moses","year":"2012","journal-title":"PloS One."},{"issue":"2-3","key":"2021122204023621200_CIT0018","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0022-3956(85)90022-6","article-title":"Evaluation of growth in anorexia nervosa from serial measurements","volume":"19","author":"Nielsen","year":"1985","journal-title":"J Psychiatr Res."},{"key":"2021122204023621200_CIT0019","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.bone.2018.03.022","article-title":"Longitudinal changes in bone parameters in young girls with anorexia nervosa","volume":"116","author":"Shepherd","year":"2018","journal-title":"Bone."},{"issue":"6","key":"2021122204023621200_CIT0020","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.jadohealth.2006.09.011","article-title":"Bone changes in adolescent girls with anorexia nervosa","volume":"39","author":"Stone","year":"2006","journal-title":"J Adolesc Health."},{"issue":"2","key":"2021122204023621200_CIT0021","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/ejcn.2013.244","article-title":"Long-term effects of enteral feeding on growth and mental health in adolescents with anorexia nervosa\u2014results of a retrospective German cohort study","volume":"68","author":"Nehring","year":"2014","journal-title":"Eur J Clin Nutr."},{"issue":"6","key":"2021122204023621200_CIT0022","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0197-0070(85)80052-8","article-title":"Short stature in anorexia nervosa patients","volume":"6","author":"Nussbaum","year":"1985","journal-title":"J Adolesc Health Care."},{"issue":"5","key":"2021122204023621200_CIT0023","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0022-3476(85)80369-3","article-title":"Follow-up investigation in patients with anorexia nervosa","volume":"106","author":"Nussbaum","year":"1985","journal-title":"J Pediatr."},{"issue":"6","key":"2021122204023621200_CIT0024","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1542\/peds.2004-0540","article-title":"Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls","volume":"114","author":"Misra","year":"2004","journal-title":"Pediatrics."},{"issue":"4","key":"2021122204023621200_CIT0025","first-page":"527","article-title":"Selected auxological aspects of anorexia nervosa\u2014relations of body weight to body height and menstrual cycle","volume":"28","author":"Kr\u00e1snicanov\u00e1","year":"2007","journal-title":"Neuro Endocrinol Lett."},{"issue":"4","key":"2021122204023621200_CIT0026","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/eat.22840","article-title":"Outcome of childhood anorexia nervosa-the results of a five- to ten-year follow-up study","volume":"51","author":"Herpertz-Dahlmann","year":"2018","journal-title":"Int J Eat Disord."},{"issue":"1","key":"2021122204023621200_CIT0027","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0002-7138(09)60726-3","article-title":"Anorexia nervosa: a quantitative approach to follow-up","volume":"20","author":"Rollins","year":"1981","journal-title":"J Am Acad Child Psychiatry."},{"issue":"7","key":"2021122204023621200_CIT0028","doi-asserted-by":"crossref","first-page":"e0181104","DOI":"10.1371\/journal.pone.0181104","article-title":"Predictors and long-term health outcomes of eating disorders","volume":"12","author":"O\u2019Brien","year":"2017","journal-title":"PloS One."},{"issue":"3","key":"2021122204023621200_CIT0029","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1365-2265.2007.02912.x","article-title":"Predictors of late menarche and adult height in children with anorexia nervosa","volume":"67","author":"Roz\u00e9","year":"2007","journal-title":"Clin Endocrinol (Oxf)."},{"issue":"5","key":"2021122204023621200_CIT0030","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/erv.2237","article-title":"Poor catch-up growth in late adolescent boys with eating disorders, weight loss and stunting of growth","volume":"21","author":"Swenne","year":"2013","journal-title":"Eur Eat Disord Rev."},{"issue":"2","key":"2021122204023621200_CIT0031","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.jadohealth.2019.08.032","article-title":"What are the effects of restrictive eating disorders on growth and puberty and are effects permanent? A systematic review and meta-analysis","volume":"66","author":"Neale","year":"2020","journal-title":"J Adolesc Health."},{"issue":"10","key":"2021122204023621200_CIT0032","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1210\/jc.2011-1222","article-title":"Endocrine dysregulation in anorexia nervosa update","volume":"96","author":"Miller","year":"2011","journal-title":"J Clin Endocrinol Metab."},{"issue":"4","key":"2021122204023621200_CIT0033","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0022-3476(94)70030-3","article-title":"Disturbances in growth hormone secretion and action in adolescents with anorexia nervosa","volume":"125","author":"Golden","year":"1994","journal-title":"J Pediatr."},{"issue":"4","key":"2021122204023621200_CIT0034","first-page":"1346","article-title":"Low serum levels of free and total insulin-like growth factor I (IGF-I) in patients with anorexia nervosa are not associated with increased IGF-binding protein-3 proteolysis","volume":"84","author":"St\u00f8ving","year":"1999","journal-title":"J Clin Endocrinol Metab."},{"issue":"4-5","key":"2021122204023621200_CIT0035","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000184187","article-title":"Hormonal and nutritional regulation of IGF-I and its binding proteins","volume":"42","author":"Underwood","year":"1994","journal-title":"Horm Res."},{"key":"2021122204023621200_CIT0036","volume-title":"Structured Clinical Interview for DSM-IV Axis I Disorders, Patient Edition, January 1995 FINAL, SCID-I\/P Version 2.0).","author":"First","year":"1995"},{"key":"2021122204023621200_CIT0037","article-title":"Task Force on DSM-IV","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-IV.","author":"American Psychiatric Association","year":"1994","edition":"4th ed"},{"issue":"6","key":"2021122204023621200_CIT0038","doi-asserted-by":"crossref","first-page":"E108","DOI":"10.1542\/peds.108.6.e108","article-title":"Comparison of body weight and height of Israeli schoolchildren with the Tanner and Centers for Disease Control and prevention growth charts","volume":"108","author":"Goldstein","year":"2001","journal-title":"Pediatrics."},{"issue":"2","key":"2021122204023621200_CIT0039","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jadohealth.2017.02.016","article-title":"Sex differences in the impact of thinness, overweight, obesity, and parental height on adolescent height","volume":"61","author":"Pinhas-Hamiel","year":"2017","journal-title":"J Adolesc Health."},{"issue":"3","key":"2021122204023621200_CIT0040","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1600-0447.1987.tb02903.x","article-title":"Short stature as a possible etiological factor in anorexia nervosa","volume":"76","author":"Brinch","year":"1987","journal-title":"Acta Psychiatr Scand."},{"issue":"644","key":"2021122204023621200_CIT0041","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1136\/pgmj.55.644.381","article-title":"Weight and skeletal maturation\u2014a study of radiological and chronological age in an anorexia nervosa population","volume":"55","author":"Lacey","year":"1979","journal-title":"Postgrad Med J."},{"issue":"2","key":"2021122204023621200_CIT0042","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0022-3476(67)80420-7","article-title":"A comparison of skeletal growth and maturation in undernourished and well-nourished girls before and after menarche","volume":"70","author":"Dreizen","year":"1967","journal-title":"J Pediatr."},{"issue":"4","key":"2021122204023621200_CIT0043","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1467-789X.2007.00347.x","article-title":"A comparison of direct vs. self-report measures for assessing height, weight and body mass index: a systematic review","volume":"8","author":"Connor Gorber","year":"2007","journal-title":"Obes Rev."},{"issue":"7","key":"2021122204023621200_CIT0044","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/eat.22402","article-title":"Time trends in lifetime incidence rates of first-time diagnosed anorexia nervosa and bulimia nervosa across 16 years in a Danish nationwide psychiatric registry study","volume":"48","author":"Steinhausen","year":"2015","journal-title":"Int J Eat Disord."},{"issue":"2","key":"2021122204023621200_CIT0045","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1177\/0141076815617651","article-title":"Trends in hospital admission rates for anorexia nervosa in Oxford (1968-2011) and England (1990-2011): database studies","volume":"109","author":"Holland","year":"2016","journal-title":"J R Soc Med."},{"issue":"6","key":"2021122204023621200_CIT0046","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/13803395.2019.1610160","article-title":"A process approach to verbal memory assessment: exploratory evidence of inefficient learning in women remitted from anorexia nervosa","volume":"41","author":"Stedal","year":"2019","journal-title":"J Clin Exp Neuropsychol."},{"issue":"7","key":"2021122204023621200_CIT0047","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1002\/ijc.28495","article-title":"Cancer incidence and mortality patterns in women with anorexia nervosa","volume":"134","author":"Karamanis","year":"2014","journal-title":"Int J Cancer."},{"issue":"3","key":"2021122204023621200_CIT0048","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/eat.22483","article-title":"Obstetric and gynecologic problems associated with eating disorders","volume":"49","author":"Kimmel","year":"2016","journal-title":"Int J Eat Disord."},{"key":"2021122204023621200_CIT0049","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1159\/000342601","article-title":"Bone mineral accretion and its relationship to growth, sexual maturation and body composition during childhood and adolescence","volume":"106","author":"Zemel","year":"2013","journal-title":"World Rev Nutr Diet."}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgaa510\/33649366\/dgaa510.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/106\/1\/e1\/41847535\/dgaa510.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/106\/1\/e1\/41847535\/dgaa510.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T03:33:39Z","timestamp":1667964819000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/106\/1\/e1\/5892224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,20]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,8,20]]},"published-print":{"date-parts":[[2021,1,1]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgaa510","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1,1]]},"published":{"date-parts":[[2020,8,20]]}}}