{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:58:21Z","timestamp":1791979101227,"version":"4.4.0"},"reference-count":37,"publisher":"The Endocrine Society","issue":"5","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100008871","name":"Juvenile Diabetes Research Foundation","doi-asserted-by":"crossref","award":["CCTN 1103"],"award-info":[{"award-number":["CCTN 1103"]}],"id":[{"id":"10.13039\/100008871","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Celiac disease (CD) is a common comorbidity seen in patients with type 1 diabetes (T1D) and is frequently asymptomatic. As chronic conditions requiring significant lifestyle changes, there are limited reports assessing changes in health-related quality of life (HRQoL) during transition to a gluten-free diet (GFD) in patients with T1D who are asymptomatic for CD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This work aims to prospectively assess HRQoL and health perception in children and adults with T1D and asymptomatic CD after random assignment to GFD vs usual diet.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients with T1D aged 8 to 45 years without CD symptoms were serologically screened for CD, with positive results confirmed with intestinal biopsy. Participants were randomly assigned in an open-label fashion to a GFD or gluten-containing diet (GCD) for 12 months. Generic and diabetes-specific HRQoL and self-perceived wellness (SPW) were assessed longitudinally.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 2387 T1D patients were serologically screened. CD was biopsy-confirmed in 82 patients and 51 participants were randomly assigned to a GFD (N\u2005=\u200527) or GCD (N\u2005=\u200524). Excellent adherence to the assigned diets was observed. Overall, no changes in generic (P\u2005=\u2005.73) or diabetes-specific HRQoL (P\u2005=\u2005.30), or SPW (P\u2005=\u2005.41) were observed between groups over 12 months. Hemoglobin A1c (HbA1c) and gastrointestinal symptoms were consistent predictors of HRQoL and SPW.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>HRQoL and SPW were not significantly affected by the adoption of a GFD over 12 months, but worsened with symptom onset and increased HbA1c. Our findings indicate that transition to a GFD can be made successfully in this population without adversely affecting quality of life.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/clinem\/dgaa977","type":"journal-article","created":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T23:54:49Z","timestamp":1612310089000},"page":"e1984-e1992","source":"Crossref","is-referenced-by-count":15,"title":["Impact of a Gluten-Free Diet on Quality of Life and Health Perception in Patients With Type 1 Diabetes and Asymptomatic Celiac Disease"],"prefix":"10.1210","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2410-4678","authenticated-orcid":false,"given":"Daniel I","family":"Weiman","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3557-3584","authenticated-orcid":false,"given":"Farid H","family":"Mahmud","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3001-0213","authenticated-orcid":false,"given":"Antoine B M","family":"Clarke","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4278-8580","authenticated-orcid":false,"given":"Esther","family":"Assor","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4988-8480","authenticated-orcid":false,"given":"Charlotte","family":"McDonald","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, St. Joseph\u2019s Health Care, Western University, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6767-4021","authenticated-orcid":false,"given":"Fred","family":"Saibil","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3820-7897","authenticated-orcid":false,"given":"Heather A","family":"Lochnan","sequence":"additional","affiliation":[{"name":"Department of Medicine and The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4894-3617","authenticated-orcid":false,"given":"Zubin","family":"Punthakee","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, McMaster University, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3850-1989","authenticated-orcid":false,"given":"Margaret A","family":"Marcon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"CD-DIET Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farid H","family":"Mahmud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine B M","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Assor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Saibil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather A","family":"Lochnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubin","family":"Punthakee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amish","family":"Parikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Advani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baiju R","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce A","family":"Perkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline S","family":"Zuijdwijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R","family":"Mack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dror","family":"Koltin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia N","family":"De Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geetha","family":"Mukerji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Bax","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret L","family":"Lawson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Cino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie D","family":"Beaton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navaaz A","family":"Saloojee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia H","family":"Gallego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Permysl","family":"Bercik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn L","family":"Houlden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronnie","family":"Aronson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E","family":"Kirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William G","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret A","family":"Marcon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"key":"2021122204520883600_CIT0001","doi-asserted-by":"crossref","first-page":"161285","DOI":"10.1155\/2010\/161285","article-title":"Celiac disease and pediatric type 1 diabetes: diagnostic and treatment dilemmas","volume":"2010","author":"Sud","year":"2010","journal-title":"Int J Pediatr Endocrinol."},{"issue":"3","key":"2021122204520883600_CIT0002","doi-asserted-by":"crossref","first-page":"631","DOI":"10.2337\/diacare.26.3.631","article-title":"The PedsQL in type 1 and type 2 diabetes","volume":"26","author":"Varni","year":"2003","journal-title":"Diabetes Care."},{"issue":"1","key":"2021122204520883600_CIT0003","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1399-5448.2010.00653.x","article-title":"Health-related quality of life (HRQoL) of children with type 1 diabetes mellitus (T1DM): self and parental perceptions","volume":"12","author":"Kalyva","year":"2011","journal-title":"Pediatr Diabetes."},{"issue":"10","key":"2021122204520883600_CIT0004","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1111\/j.1651-2227.2003.tb02483.x","article-title":"Measuring self-reported, health-related, quality of life in adolescents with type 1 diabetes using both generic and disease-specific instruments","volume":"92","author":"Graue","year":"2003","journal-title":"Acta Paediatr."},{"issue":"2","key":"2021122204520883600_CIT0005","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/MPG.0b013e31815ef87d","article-title":"CDDUX: a disease-specific health-related quality-of-life questionnaire for children with celiac disease","volume":"47","author":"van Doorn","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr."},{"issue":"8","key":"2021122204520883600_CIT0006","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S1590-8658(02)80087-1","article-title":"Case control study on health-related quality of life in adult coeliac disease","volume":"34","author":"Usai","year":"2002","journal-title":"Dig Liver Dis."},{"issue":"9","key":"2021122204520883600_CIT0007","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1080\/003655298750026949","article-title":"Quality of life of adult coeliac patients treated for 10 years","volume":"33","author":"Hallert","year":"1998","journal-title":"Scand J Gastroenterol."},{"issue":"11","key":"2021122204520883600_CIT0008","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.jada.2003.08.027","article-title":"Celiac diet: its impact on quality of life","volume":"103","author":"Lee","year":"2003","journal-title":"J Am Diet Assoc."},{"issue":"6","key":"2021122204520883600_CIT0009","doi-asserted-by":"crossref","first-page":"e754","DOI":"10.1542\/peds.2005-0904","article-title":"Celiac disease: evaluation of the diagnosis and dietary compliance in Canadian children","volume":"116","author":"Rashid","year":"2005","journal-title":"Pediatrics."},{"issue":"1","key":"2021122204520883600_CIT0010","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.dld.2008.05.011","article-title":"Quality of life in celiac disease patients: prospective analysis on the importance of clinical severity at diagnosis and the impact of treatment","volume":"41","author":"Nachman","year":"2009","journal-title":"Dig Liver Dis."},{"issue":"2","key":"2021122204520883600_CIT0011","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.cgh.2010.10.011","article-title":"Diet improves perception of health and well-being in symptomatic, but not asymptomatic, patients with celiac disease","volume":"9","author":"Ukkola","year":"2011","journal-title":"Clin Gastroenterol Hepatol."},{"issue":"2","key":"2021122204520883600_CIT0012","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.clnu.2016.04.021","article-title":"Systematic review with meta-analysis: dietary adherence influences normalization of health-related quality of life in coeliac disease","volume":"36","author":"Burger","year":"2017","journal-title":"Clin Nutr."},{"issue":"7","key":"2021122204520883600_CIT0013","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.2337\/dc19-1944","article-title":"Screening and treatment outcomes in adults and children with type 1 diabetes and asymptomatic celiac disease: the CD-DIET study","volume":"43","author":"Mahmud","year":"2020","journal-title":"Diabetes Care."},{"key":"2021122204520883600_CIT0014","article-title":"Figshare","author":"Weiman","year":"2020"},{"issue":"6","key":"2021122204520883600_CIT0015","first-page":"1373","article-title":"Gastrointestinal symptoms and health related quality of life in patients with arthritis","volume":"27","author":"Wolfe","year":"2000","journal-title":"J Rheumatol."},{"issue":"4","key":"2021122204520883600_CIT0016","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/01.rhu.0000173616.81928.44","article-title":"Gastrointestinal symptoms and their association with health-related quality of life of children with juvenile rheumatoid arthritis: validation of a gastrointestinal symptom questionnaire","volume":"11","author":"Brunner","year":"2005","journal-title":"J Clin Rheumatol."},{"issue":"5","key":"2021122204520883600_CIT0017","doi-asserted-by":"crossref","first-page":"e008097","DOI":"10.1136\/bmjopen-2015-008097","article-title":"The Celiac Disease and Diabetes-Dietary Intervention and Evaluation Trial (CD-DIET) protocol: a randomised controlled study to evaluate treatment of asymptomatic coeliac disease in type 1 diabetes","volume":"5","author":"Mahmud","year":"2015","journal-title":"BMJ Open."},{"issue":"5","key":"2021122204520883600_CIT0018","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.cgh.2008.12.032","article-title":"A simple validated gluten-free diet adherence survey for adults with celiac disease","volume":"7","author":"Leffler","year":"2009","journal-title":"Clin Gastroenterol Hepatol."},{"issue":"8","key":"2021122204520883600_CIT0019","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1097\/00005650-200108000-00006","article-title":"PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations","volume":"39","author":"Varni","year":"2001","journal-title":"Med Care."},{"issue":"8","key":"2021122204520883600_CIT0020","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1007\/s11136-012-0339-8","article-title":"Content validity of the PedsQL 3.2 Diabetes Module in newly diagnosed patients with Type 1 diabetes mellitus ages 8-45","volume":"22","author":"Varni","year":"2013","journal-title":"Qual Life Res."},{"issue":"10","key":"2021122204520883600_CIT0021","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.2337\/dc17-2707","article-title":"PedsQL 3.2 diabetes module for children, adolescents, and young adults: reliability and validity in type 1 diabetes","volume":"41","author":"Varni","year":"2018","journal-title":"Diabetes Care."},{"issue":"2","key":"2021122204520883600_CIT0022","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1399-5448.2011.00785.x","article-title":"Quality of life in children with diabetes and celiac disease: minimal impact of the \u2018double diagnosis\u2019","volume":"13","author":"Sud","year":"2012","journal-title":"Pediatr Diabetes."},{"issue":"10","key":"2021122204520883600_CIT0023","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.2337\/dc11-0149","article-title":"High prevalence of microvascular complications in adults with type 1 diabetes and newly diagnosed celiac disease","volume":"34","author":"Leeds","year":"2011","journal-title":"Diabetes Care."},{"issue":"1","key":"2021122204520883600_CIT0024","doi-asserted-by":"crossref","first-page":"e239","DOI":"10.1038\/nutd.2016.43","article-title":"Impact of type 1 diabetes mellitus and celiac disease on nutrition and quality of life","volume":"7","author":"Nunes-Silva","year":"2017","journal-title":"Nutr Diabetes."},{"key":"2021122204520883600_CIT0025","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jpeds.2016.08.105","article-title":"Quality of life in type 1 diabetes and celiac disease: role of the gluten-free diet","volume":"179","author":"Pham-Short","year":"2016","journal-title":"J Pediatr."},{"key":"2021122204520883600_CIT0026","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jclinepi.2017.06.009","article-title":"Minimal important difference to infer changes in health-related quality of life-a systematic review","volume":"89","author":"Jayadevappa","year":"2017","journal-title":"J Clin Epidemiol."},{"issue":"10","key":"2021122204520883600_CIT0027","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.2337\/dc12-2109","article-title":"The long-term effects of type 1 diabetes treatment and complications on health-related quality of life: a 23-year follow-up of the Diabetes Control and Complications\/Epidemiology of Diabetes Interventions and Complications cohort","volume":"36","author":"Jacobson","year":"2013","journal-title":"Diabetes Care."},{"issue":"2","key":"2021122204520883600_CIT0028","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jpeds.2012.01.016","article-title":"Demographic and clinical correlates of diabetes-related quality of life among youth with type 1 diabetes","volume":"161","author":"Lawrence","year":"2012","journal-title":"J Pediatr."},{"issue":"3","key":"2021122204520883600_CIT0029","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/(SICI)1520-7560(199905\/06)15:3<205::AID-DMRR29>3.0.CO;2-O","article-title":"Quality of life and diabetes","volume":"15","author":"Rubin","year":"1999","journal-title":"Diabetes Metab Res Rev."},{"issue":"4","key":"2021122204520883600_CIT0030","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/ijo.2009.42","article-title":"Health-related quality of life in obese children and adolescents","volume":"33","author":"Tsiros","year":"2009","journal-title":"Int J Obes (Lond)."},{"issue":"1","key":"2021122204520883600_CIT0031","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3748\/wjg.14.46","article-title":"Factors that impact health-related quality of life in adults with celiac disease: a multicenter study","volume":"14","author":"Casellas","year":"2008","journal-title":"World J Gastroenterol."},{"key":"2021122204520883600_CIT0032","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1471-230X-13-75","article-title":"Predictors of persistent symptoms and reduced quality of life in treated coeliac disease patients: a large cross-sectional study","volume":"13","author":"Paarlahti","year":"2013","journal-title":"BMC Gastroenterol."},{"issue":"4","key":"2021122204520883600_CIT0033","doi-asserted-by":"crossref","first-page":"e582","DOI":"10.1542\/peds.2008-2221","article-title":"Long-term health and quality-of-life consequences of mass screening for childhood celiac disease: a 10-year follow-up study","volume":"123","author":"van Koppen","year":"2009","journal-title":"Pediatrics."},{"key":"2021122204520883600_CIT0034","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/1471-2458-13-142","article-title":"Health-related quality of life in adolescents with screening-detected celiac disease, before and one year after diagnosis and initiation of gluten-free diet, a prospective nested case-referent study","volume":"13","author":"Nordyke","year":"2013","journal-title":"BMC Public Health."},{"issue":"12","key":"2021122204520883600_CIT0035","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1097\/00042737-200412000-00008","article-title":"Quality of life in screen-detected and typical coeliac disease and the effect of excluding dietary gluten","volume":"16","author":"Johnston","year":"2004","journal-title":"Eur J Gastroenterol Hepatol."},{"issue":"3","key":"2021122204520883600_CIT0036","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1053\/j.gastro.2014.05.003","article-title":"Benefits of a gluten-free diet for asymptomatic patients with serologic markers of celiac disease","volume":"147","author":"Kurppa","year":"2014","journal-title":"Gastroenterology."},{"issue":"8","key":"2021122204520883600_CIT0037","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1155\/2010\/140289","article-title":"Long-term management of patients with celiac disease: current practices of gastroenterologists in Canada","volume":"24","author":"Silvester","year":"2010","journal-title":"Can J Gastroenterol."}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgaa977\/36741007\/dgaa977.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/106\/5\/e1984\/41848234\/dgaa977.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/106\/5\/e1984\/41848234\/dgaa977.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T04:53:44Z","timestamp":1640148824000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/106\/5\/e1984\/6125716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":37,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,2,1]]},"published-print":{"date-parts":[[2021,4,23]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgaa977","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,5,1]]},"published":{"date-parts":[[2021,2,1]]}}}