{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:45:13Z","timestamp":1790700313750,"version":"4.1.0"},"reference-count":40,"publisher":"The Endocrine Society","issue":"12","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Merck"},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Lilly"},{"name":"Ferring"},{"DOI":"10.13039\/100011218","name":"Sandoz","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100011218","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100014382","name":"Ipsen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Prematurity carries a risk for impaired postnatal growth and long-term growth restriction. Especially children born SGA seem vulnerable for poor growth, as a persistent short stature can be observed in app 10-15% of these children.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>In this study we aimed to recognize differences in growth patterns of children according to sex, maturity, and auxological status at birth facilitating earlier identification of small-for-gestational-age (SGA) children with adult short stature.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The growth data of 44\u2005791 infants born between January 1, 1980, and December 30, 2012, among 2 pediatric cohorts with follow-up through December 31, 2020, were analyzed. A total of 5698 children with birth data had measurements at near final height (nfh) and at least 2 further points.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Preterm children (gestational age &amp;lt;\u200537 weeks) had a significantly lower mean nfh SDS than term children (preterm, \u22120.61; term, \u22120.18) and a higher likelihood of nfh &amp;lt;\u2005third percentile (preterm, 20.5%; term, 12.2%). SGA born children also had a lower mean nfh SD score (SDS) than children born appropriate for gestational age (AGA) (SGA, \u22121.06; AGA, \u22120.15) and a higher likelihood of nfh &amp;lt;\u2005third percentile (SGA, 28.2%; AGA 10.1%). Of 1204 SGA children, 672 (56%) showed successful catch-up growth (CUG) to nfh greater than or equal to the 10th percentile (SGA-CU), and 532 children (44%) did not (SGA-S). The difference in their mean nfh SDS (SGA-CU, \u22120.12; SGA-S \u22122.26) can only partly be explained by the differences in mean mid-parental height SDS (SGA-CU, \u22120.3; SGA-S, \u22121.19). During the first year, SGA-CU showed higher CUG (SGA-CU, +1.2 SDS; SGA-S, +0.45 SDS), which helps to discriminate between groups earlier.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Final growth outcome was influenced by prematurity and auxological status at birth, but not by sex. Height\/length SDS increments during year 1 are instrumental to discern SGA children with later normal or short stature. While observing CUG until year 2 and 3 can add specificity, discrimination thereafter becomes difficult.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/clinem\/dgac510","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T19:14:07Z","timestamp":1663096447000},"page":"3320-3327","source":"Crossref","is-referenced-by-count":11,"title":["Growth Patterns of Children With Short Stature in Adulthood According to Auxological Status and Maturity at Birth"],"prefix":"10.1210","volume":"107","author":[{"given":"Roland","family":"Pf\u00e4ffle","sequence":"first","affiliation":[{"name":"Hospital for Children and Adolescents, University of Leipzig , 04103 Leipzig , Germany"},{"name":"CrescNet Database, University of Leipzig , 04103 Leipzig , 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