{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:50:14Z","timestamp":1789091414740,"version":"build-2803163510"},"reference-count":47,"publisher":"The Endocrine Society","issue":"9","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2019\/15873-6"],"award-info":[{"award-number":["2019\/15873-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>The role of hormone parameters at adrenal venous sampling (AVS) in predicting clinical and biochemical outcomes remains controversial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the impact of hormone parameters at AVS under cosyntropin stimulation on lateralization and on complete biochemical and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively evaluated 150 sequential AVS under cosyntropin infusion. The bilateral successful cannulation rate was 83.3% (n = 140), 47.9% bilateral and 52.1% unilateral. The lateralization index, aldosterone\/cortisol ratio (A\/C) in the dominant adrenal vein (AV), and relative aldosterone secretion index (RASI = A\/C in AV divided by A\/C in inferior vena cava) were assessed. The contralateral suppression (CS) percentage was defined by (1 \u2212 nondominant RASI) * 100.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A nondominant RASI &amp;lt;0.5 (CS &amp;gt;50%) had 86.84% sensitivity and 92.96% specificity to predict contralateral lateralization. An A\/C ratio in dominant AV &amp;gt;5.9 (74.67% sensitivity and 80% specificity) and dominant RASI &amp;gt;4.7 (35.21% sensitivity and 88.06% specificity) had the worst performance to predict ipsilateral lateralization. Complete biochemical and clinical cure was significantly more frequent in the patients with CS &amp;gt;50% [98.41% vs 42.86% (P &amp;lt; .001) and 41.94% vs 0% (P &amp;lt; .001)]. CS correlated with high aldosterone at diagnosis (P &amp;lt; .001) and low postoperative aldosterone levels at 1 month (P = .019). Postoperative biochemical hypoaldosteronism was more frequent in patients with CS &amp;gt;50% (70% vs 16.67%, P = .014). In multivariable analysis, a CS &amp;gt;50% was associated with complete biochemical cure [odds ratio (OR) 125, 95% confidence interval (CI) 11.904-5000; P = .001] and hypertension remission (OR 12.19, 95% CI 2.074-250; P = .023).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A CS &amp;gt;50% was an independent predictor of complete clinical and biochemical cure. Moreover, it can predict unilateral primary aldosteronism and postoperative biochemical hypoaldosteronism. Our findings underscore the usefulness of CS for clinical decision-making.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgae142","type":"journal-article","created":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T17:22:06Z","timestamp":1709572926000},"page":"2282-2293","source":"Crossref","is-referenced-by-count":16,"title":["Contralateral Suppression in Adrenal Venous Sampling Predicts Clinical and Biochemical Outcome in Primary Aldosteronism"],"prefix":"10.1210","volume":"109","author":[{"given":"Jessica","family":"Okubo","sequence":"first","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Frudit","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline C B S","family":"Cavalcante","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Radiologia Intervencionista, Instituto de Radiologia InRAD, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana A W","family":"Maciel","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thais C","family":"Freitas","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"Pilan","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Radiologia Intervencionista, Instituto de Radiologia InRAD, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo F C","family":"Fagundes","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nara L","family":"Queiroz","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheo A M","family":"Stumpf","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor C M","family":"Souza","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo Z","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana S","family":"Goldbaum","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Adelaide A","family":"Pereira","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinicius F","family":"Calsavara","sequence":"additional","affiliation":[{"name":"Department of Computational Biomedicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center , Los Angeles, CA 90069 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando M A","family":"Coelho","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Radiologia, Instituto de Radiologia InRAD, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor","family":"Srougi","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Urologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio Y","family":"Tanno","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Urologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose L","family":"Chambo","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Urologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz A","family":"Bortolotto","sequence":"additional","affiliation":[{"name":"Unidade de Hipertens\u00e3o, Instituto do Cora\u00e7\u00e3o (InCOR), Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-900 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano F","family":"Drager","sequence":"additional","affiliation":[{"name":"Unidade de Hipertens\u00e3o, Instituto do Cora\u00e7\u00e3o (InCOR), Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-900 ,","place":["Brazil"]},{"name":"Unidade de Hipertens\u00e3o, Divisi\u00e3o de Nefrologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6150-1915","authenticated-orcid":false,"given":"Maria Candida B V","family":"Fragoso","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Horm\u00f4nios e Gen\u00e9tica Molecular LIM42, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo, 01246-903 ,","place":["Brazil"]},{"name":"Unidade de Oncologia End\u00f3crina, Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo (ICESP), Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Claudia","family":"Latronico","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berenice B","family":"Mendonca","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Horm\u00f4nios e Gen\u00e9tica Molecular LIM42, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo, 01246-903 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco C","family":"Carnevale","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Radiologia Intervencionista, Instituto de Radiologia InRAD, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2957-6148","authenticated-orcid":false,"given":"Madson Q","family":"Almeida","sequence":"additional","affiliation":[{"name":"Unidade de Adrenal, Laborat\u00f3rio de Endocrinologia Molecular e Celular LIM25, Divis\u00e3o de Endocrinologia e Metabologia, Hospital das Cl\u00ednicas, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-903 ,","place":["Brazil"]},{"name":"Unidade de Oncologia End\u00f3crina, Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo (ICESP), Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo 01246-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2024,3,5]]},"reference":[{"issue":"14","key":"2026041420191754100_dgae142-B1","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/j.jacc.2017.01.052","article-title":"Prevalence and clinical manifestations of primary aldosteronism encountered in primary care practice","volume":"69","author":"Monticone","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"2026041420191754100_dgae142-B2","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","article-title":"A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients","volume":"48","author":"Rossi","year":"2006","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"2026041420191754100_dgae142-B3","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"2026041420191754100_dgae142-B4","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1210\/clinem\/dgac460","article-title":"Approach to the patient on antihypertensive therapy: screen for primary aldosteronism","volume":"107","author":"Mulatero","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"2026041420191754100_dgae142-B5","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1590\/2359-3997000000274","article-title":"Diagnosis and management of primary aldosteronism","volume":"61","author":"Vilela","year":"2017","journal-title":"Arch Endocrinol Metab"},{"issue":"10 Pt 1","key":"2026041420191754100_dgae142-B6","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0895-7061(02)02969-2","article-title":"High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives","volume":"15","author":"Rossi","year":"2002","journal-title":"Am J Hypertens"},{"issue":"1","key":"2026041420191754100_dgae142-B7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.7326\/M20-1758","article-title":"Primary aldosteronism: at the tipping point","volume":"173","author":"Funder","year":"2020","journal-title":"Ann Intern Med"},{"issue":"12","key":"2026041420191754100_dgae142-B8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s11906-020-01106-5","article-title":"What is the most common cause of secondary hypertension?: an interdisciplinary discussion","volume":"22","author":"Almeida","year":"2020","journal-title":"Curr Hypertens Rep"},{"issue":"9","key":"2026041420191754100_dgae142-B9","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1515\/cclm-2015-1094","article-title":"Prospective validation of an automated chemiluminescence-based assay of renin and aldosterone for the work-up of arterial hypertension","volume":"54","author":"Rossi","year":"2016","journal-title":"Clin Chem Lab Med"},{"issue":"3","key":"2026041420191754100_dgae142-B10","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1161\/HYPERTENSIONAHA.120.16429","article-title":"Intraindividual variability of aldosterone concentrations in primary aldosteronism: implications for case detection","volume":"77","author":"Yozamp","year":"2021","journal-title":"Hypertension"},{"issue":"5","key":"2026041420191754100_dgae142-B11","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1210\/clinem\/dgac679","article-title":"Intra-individual variability of serum aldosterone and implications for primary aldosteronism screening","volume":"108","author":"Maciel","year":"2023","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2026041420191754100_dgae142-B12","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1210\/clinem\/dgz017","article-title":"Subtyping of primary aldosteronism in the AVIS-2 study: assessment of selectivity and lateralization","volume":"105","author":"Rossitto","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2026041420191754100_dgae142-B13","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/HYPERTENSIONAHA.113.02097","article-title":"An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism","volume":"63","author":"Rossi","year":"2014","journal-title":"Hypertension"},{"issue":"8","key":"2026041420191754100_dgae142-B14","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1210\/jc.2013-4146","article-title":"Accuracy of adrenal imaging and adrenal venous sampling in predicting surgical cure of primary aldosteronism","volume":"99","author":"Lim","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"2026041420191754100_dgae142-B15","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1161\/HYPERTENSIONAHA.121.16498","article-title":"Genetics of primary aldosteronism","volume":"79","author":"Scholl","year":"2022","journal-title":"Hypertension"},{"issue":"9","key":"2026041420191754100_dgae142-B16","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1038\/ng.2695","article-title":"Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism","volume":"45","author":"Scholl","year":"2013","journal-title":"Nat Genet"},{"key":"2026041420191754100_dgae142-B17","doi-asserted-by":"crossref","first-page":"e06315","DOI":"10.7554\/eLife.06315","article-title":"Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism","volume":"4","author":"Scholl","year":"2015","journal-title":"Elife"},{"issue":"3","key":"2026041420191754100_dgae142-B18","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41588-018-0048-5","article-title":"CLCN2 chloride channel mutations in familial hyperaldosteronism type II","volume":"50","author":"Scholl","year":"2018","journal-title":"Nat Genet"},{"issue":"3","key":"2026041420191754100_dgae142-B19","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41588-018-0053-8","article-title":"A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism","volume":"50","author":"Fernandes-Rosa","year":"2018","journal-title":"Nat Genet"},{"issue":"6","key":"2026041420191754100_dgae142-B20","doi-asserted-by":"crossref","first-page":"R185","DOI":"10.1530\/EJE-20-0863","article-title":"Management of endocrine disease: the role of surgical adrenalectomy in primary aldosteronism","volume":"183","author":"Hundemer","year":"2020","journal-title":"Eur J Endocrinol"},{"issue":"7","key":"2026041420191754100_dgae142-B21","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1210\/jc.2008-2803","article-title":"Role of Unilateral Adrenalectomy in Bilateral Primary Aldosteronism: A 22-Year Single Center Experience","volume":"94","author":"Sukor","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2026041420191754100_dgae142-B22","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1161\/HYPERTENSIONAHA.118.11086","article-title":"Cellular and genetic causes of idiopathic hyperaldosteronism","volume":"72","author":"Omata","year":"2018","journal-title":"Hypertension"},{"issue":"4","key":"2026041420191754100_dgae142-B23","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1210\/jc.2018-01324","article-title":"Adrenal venous sampling with or without adrenocorticotropic hormone stimulation: a meta-analysis","volume":"104","author":"Laurent","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"2026041420191754100_dgae142-B24","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1161\/HYPERTENSIONAHA.123.21247","article-title":"Unilaterally selective adrenal vein sampling for identification of surgically curable primary aldosteronism","volume":"80","author":"Rossi","year":"2023","journal-title":"Hypertension"},{"issue":"4","key":"2026041420191754100_dgae142-B25","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.surg.2017.10.012","article-title":"Primary aldosteronism: making sense of partial data sets from failed adrenal venous sampling-suppression of adrenal aldosterone production can be used in clinical decision making","volume":"163","author":"Strajina","year":"2018","journal-title":"Surgery"},{"issue":"2","key":"2026041420191754100_dgae142-B26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/cen.14210","article-title":"Performance of the unilateral AV\/IVC index in primary hyperaldosteronism subtype prediction: a validation study in a single tertiary centre","volume":"93","author":"Suntornlohanakul","year":"2020","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"6","key":"2026041420191754100_dgae142-B27","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/cen.14794","article-title":"Subtyping primary aldosteronism by inconclusive adrenal vein sampling: a derivation and validation study in a tertiary centre","volume":"97","author":"Tomsic","year":"2022","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"4","key":"2026041420191754100_dgae142-B28","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1210\/jc.2014-3676","article-title":"Does contralateral suppression at adrenal venous sampling predict outcome following unilateral adrenalectomy for primary aldosteronism? A retrospective study","volume":"100","author":"Wolley","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2026041420191754100_dgae142-B29","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1530\/EJE-20-0254","article-title":"Basal contralateral aldosterone suppression is rare in lateralized primary aldosteronism","volume":"183","author":"Desrochers","year":"2020","journal-title":"Eur J Endocrinol"},{"issue":"11","key":"2026041420191754100_dgae142-B30","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1210\/jc.2014-2345","article-title":"Aldosterone suppression on contralateral adrenal during adrenal vein sampling does not predict blood pressure response after adrenalectomy","volume":"99","author":"Monticone","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"2026041420191754100_dgae142-B31","doi-asserted-by":"crossref","first-page":"7487","DOI":"10.1245\/s10434-021-09692-7","article-title":"Contralateral suppression index does not predict clinical cure in patients undergoing surgery for primary aldosteronism","volume":"28","author":"Dominguez","year":"2021","journal-title":"Ann Surg Oncol"},{"issue":"5","key":"2026041420191754100_dgae142-B32","doi-asserted-by":"crossref","first-page":"e2027","DOI":"10.1210\/clinem\/dgab924","article-title":"The saline infusion test for primary aldosteronism: implications of immunoassay inaccuracy","volume":"107","author":"Eisenhofer","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2026041420191754100_dgae142-B33","doi-asserted-by":"crossref","first-page":"bvad147","DOI":"10.1210\/jendso\/bvad147","article-title":"Efficacy of oral furosemide test for primary aldosteronism diagnosis","volume":"8","author":"Freitas","year":"2023","journal-title":"J Endocr Soc"},{"issue":"2","key":"2026041420191754100_dgae142-B34","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1210\/jc.2018-01299","article-title":"Adrenal vein sampling lateralization despite mineralocorticoid receptor antagonists exposure in primary aldosteronism","volume":"104","author":"Nanba","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"issue":"33","key":"2026041420191754100_dgae142-B35","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","article-title":"2018 ESC\/ESH guidelines for the management of arterial hypertension","volume":"39","author":"Williams","year":"2018","journal-title":"Eur Heart J"},{"issue":"3 Suppl 3","key":"2026041420191754100_dgae142-B36","first-page":"7","article-title":"7th Brazilian guideline of arterial hypertension: chapter 2\u2014diagnosis and classification","volume":"107","author":"Malachias","year":"2016","journal-title":"Arq Bras Cardiol"},{"issue":"9","key":"2026041420191754100_dgae142-B37","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S2213-8587(17)30135-3","article-title":"Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort","volume":"5","author":"Williams","year":"2017","journal-title":"Lancet Diab Endocrinol"},{"issue":"10","key":"2026041420191754100_dgae142-B38","doi-asserted-by":"crossref","first-page":"4695","DOI":"10.1210\/jc.2019-00531","article-title":"KCNJ5 somatic mutation is a predictor of hypertension remission after adrenalectomy for unilateral primary aldosteronism","volume":"104","author":"Vilela","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2026041420191754100_dgae142-B39","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden","year":"1950","journal-title":"Cancer"},{"key":"2026041420191754100_dgae142-B40","doi-asserted-by":"publisher","author":"Queiroz","DOI":"10.1055\/a-2221-3302"},{"issue":"6","key":"2026041420191754100_dgae142-B41","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1177\/000313481708300624","article-title":"Considering postoperative functional hypoaldosteronism after unilateral adrenalectomy","volume":"83","author":"Starker","year":"2017","journal-title":"Am Surg"},{"issue":"5","key":"2026041420191754100_dgae142-B42","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1210\/jc.2011-2830","article-title":"The Adrenal Vein Sampling International Study (AVIS) for identifying the major subtypes of primary aldosteronism","volume":"97","author":"Rossi","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2026041420191754100_dgae142-B43","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1210\/jc.2015-3915","article-title":"Basal and post-ACTH aldosterone and its ratios are useful during adrenal vein sampling in primary aldosteronism","volume":"101","author":"Ghorayeb","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"2026041420191754100_dgae142-B44","doi-asserted-by":"crossref","first-page":"5867","DOI":"10.1210\/jc.2019-01182","article-title":"Three discrete patterns of primary aldosteronism lateralization in response to cosyntropin during adrenal vein sampling","volume":"104","author":"Wannachalee","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2026041420191754100_dgae142-B45","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/cen.14220","article-title":"Utility of adrenocorticotropic hormone in adrenal vein sampling despite the occurrence of discordant lateralization","volume":"93","author":"Chee","year":"2020","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"3","key":"2026041420191754100_dgae142-B46","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1530\/EJE-19-0860","article-title":"Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: analysis of surgical outcome","volume":"182","author":"Kobayashi","year":"2020","journal-title":"Eur J Endocrinol"},{"issue":"1","key":"2026041420191754100_dgae142-B47","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1161\/HYPERTENSIONAHA.121.17248","article-title":"Adrenocorticotropic hormone-stimulated adrenal venous sampling underestimates surgically curable primary aldosteronism: a retrospective cohort study and review of contemporary studies","volume":"78","author":"Yozamp","year":"2021","journal-title":"Hypertension"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgae142\/57096849\/dgae142.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/109\/9\/2282\/60297296\/dgae142.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/109\/9\/2282\/60297296\/dgae142.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:38:13Z","timestamp":1776213493000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/109\/9\/2282\/7621875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,5]]},"references-count":47,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,3,5]]},"published-print":{"date-parts":[[2024,8,13]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgae142","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,3,5]]}}}