{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:55:54Z","timestamp":1792173354109,"version":"4.4.0"},"reference-count":42,"publisher":"The Endocrine Society","issue":"10","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","award":["01GI0925"],"award-info":[{"award-number":["01GI0925"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"name":"German Center for Diabetes Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Breastfeeding is associated with a reduced maternal risk for cardiovascular diseases (CVDs).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Since the underlying mechanisms are still poorly understood, we here examined the effect of breastfeeding on the plasmatic coagulation system in women with and without history of gestational diabetes mellitus (GDM).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 76 participants of the German Gestational Diabetes Study (PREG; NCT04270578) were examined 14 months (interquartile range [IQR], 12-26 months) after delivery with a 5-point oral glucose tolerance test. Global coagulation tests, prothrombotic coagulation proteins (FII\/FVII\/FVIII\/FIX), antithrombotic proteins (antithrombin, protein C\/S), and endothelial markers (von Willebrand factor and plasminogen activator inhibitor 1) were determined. The Framingham risk score was used to estimate the 10-year CV risk. The effect of breastfeeding duration on coagulation was analyzed using multivariable linear models.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean duration of breastfeeding was 11 months (IQR, 7-14 months). Overall, longer duration of breastfeeding was associated with lower CV risk (Framingham risk score; P = .05) and was negatively associated with FIX (P = .018). We detected an interaction between previous GDM and breastfeeding duration for FIX (PInteraction = .017): Only in women with GDM history was the duration of breastfeeding negatively associated with FIX activity (P = .016). This association persisted in statistical models adjusted for age, body mass index, insulin sensitivity, and C-reactive protein. The duration of breastfeeding was not associated with anticoagulant proteins and endothelial markers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Longer duration of breastfeeding is associated with lower CV risk and an improved coagulation profile. Women with GDM history appear to benefit particularly from prolonged breastfeeding.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/clinem\/dgae172","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T08:16:40Z","timestamp":1710490600000},"page":"2571-2578","source":"Crossref","is-referenced-by-count":5,"title":["Effect of Breastfeeding Duration on Coagulation in Women With and Without History of Gestational Diabetes Mellitus"],"prefix":"10.1210","volume":"109","author":[{"given":"Louise","family":"Fritsche","sequence":"first","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorina","family":"L\u00f6ffler","sequence":"additional","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Department for Diabetology, Endocrinology, and Nephrology, Faculty of Medicine, Eberhard Karls University T\u00fcbingen , 72076 T\u00fcbingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0584-1138","authenticated-orcid":false,"given":"Konstantinos","family":"Kantartzis","sequence":"additional","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Department for Diabetology, Endocrinology, and Nephrology, Faculty of Medicine, Eberhard Karls University T\u00fcbingen , 72076 T\u00fcbingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gesine","family":"Flehmig","sequence":"additional","affiliation":[{"name":"Medical Department III\u2014Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center , 04103 Leipzig , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8200-6382","authenticated-orcid":false,"given":"Michael","family":"Roden","sequence":"additional","affiliation":[{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Department of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, University Hospital , 40225 D\u00fcsseldorf , Germany"},{"name":"Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University , 40225 D\u00fcsseldorf , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Fritsche","sequence":"additional","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Department for Diabetology, Endocrinology, and Nephrology, Faculty of Medicine, Eberhard Karls University T\u00fcbingen , 72076 T\u00fcbingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas L","family":"Birkenfeld","sequence":"additional","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Department for Diabetology, Endocrinology, and Nephrology, Faculty of Medicine, Eberhard Karls University T\u00fcbingen , 72076 T\u00fcbingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6160-0550","authenticated-orcid":false,"given":"Andreas","family":"Peter","sequence":"additional","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Institute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital T\u00fcbingen , 72076 T\u00fcbingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Heni","sequence":"additional","affiliation":[{"name":"Institute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital T\u00fcbingen , 72076 T\u00fcbingen , Germany"},{"name":"Division of Endocrinology and Diabetology, Department of Internal Medicine 1, University Hospital Ulm , 89070 Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5718-1530","authenticated-orcid":false,"given":"Sebastian","family":"H\u00f6rber","sequence":"additional","affiliation":[{"name":"Institute of Diabetes Research and Metabolic Diseases, Helmholtz Center Munich German Research Center for Environmental Health , 72076 T\u00fcbingen , Germany"},{"name":"German Center for Diabetes Research , 85746 Neuherberg , Germany"},{"name":"Institute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital T\u00fcbingen , 72076 T\u00fcbingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"issue":"10017","key":"2024091609272999100_dgae172-B1","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0140-6736(15)01024-7","article-title":"Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect","volume":"387","author":"Victora","year":"2016","journal-title":"Lancet"},{"issue":"1","key":"2024091609272999100_dgae172-B2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.pcl.2012.09.010","article-title":"Breastfeeding and health outcomes for the mother-infant dyad","volume":"60","author":"Dieterich","year":"2013","journal-title":"Pediatr Clin North Am"},{"issue":"2","key":"2024091609272999100_dgae172-B3","doi-asserted-by":"crossref","first-page":"e022746","DOI":"10.1161\/JAHA.121.022746","article-title":"Breastfeeding is associated with a reduced maternal cardiovascular risk: systematic review and meta-analysis involving data from 8 studies and 1 192 700 parous women","volume":"11","author":"Tschiderer","year":"2022","journal-title":"J Am Heart Assoc"},{"key":"2024091609272999100_dgae172-B4","doi-asserted-by":"crossref","first-page":"m3502","DOI":"10.1136\/bmj.m3502","article-title":"Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review","volume":"371","author":"Okoth","year":"2020","journal-title":"BMJ"},{"issue":"6","key":"2024091609272999100_dgae172-B5","doi-asserted-by":"crossref","first-page":"e006081","DOI":"10.1161\/JAHA.117.006081","article-title":"Breastfeeding and the risk of maternal cardiovascular disease: a prospective study of 300 000 Chinese women","volume":"6","author":"Peters","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"3","key":"2024091609272999100_dgae172-B6","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1177\/08903344211034779","article-title":"Protective influence of breastfeeding on cardiovascular risk factors in women with previous gestational diabetes mellitus and their children: a systematic review and meta-analysis","volume":"38","author":"Pathirana","year":"2022","journal-title":"J Hum Lact"},{"issue":"4","key":"2024091609272999100_dgae172-B7","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1365-2826.2011.02235.x","article-title":"Oxytocin revisited: its role in cardiovascular regulation","volume":"24","author":"Gutkowska","year":"2012","journal-title":"J Neuroendocrinol"},{"key":"2024091609272999100_dgae172-B8","doi-asserted-by":"crossref","first-page":"9524839","DOI":"10.1155\/2020\/9524839","article-title":"Relationship between prolactin, chronic kidney disease, and cardiovascular risk","volume":"2020","author":"Dourado","year":"2020","journal-title":"Int J Endocrinol"},{"issue":"4","key":"2024091609272999100_dgae172-B9","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/ijo.2013.132","article-title":"The relationship between breastfeeding and postpartum weight change\u2013a systematic review and critical evaluation","volume":"38","author":"Neville","year":"2014","journal-title":"Int J Obes (Lond)"},{"issue":"1","key":"2024091609272999100_dgae172-B10","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1055\/s-0028-1103034","article-title":"The reset hypothesis: lactation and maternal metabolism","volume":"26","author":"Stuebe","year":"2009","journal-title":"Am J Perinatol"},{"issue":"7","key":"2024091609272999100_dgae172-B11","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1111\/j.1538-7836.2012.04782.x","article-title":"The impact of blood coagulability on atherosclerosis and cardiovascular disease","volume":"10","author":"Loeffen","year":"2012","journal-title":"J Thromb Haemost"},{"issue":"2","key":"2024091609272999100_dgae172-B12","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1046\/j.1467-789X.2002.00056.x","article-title":"Obesity, haemostasis and the fibrinolytic system","volume":"3","author":"Mertens","year":"2002","journal-title":"Obes Rev"},{"issue":"7121","key":"2024091609272999100_dgae172-B13","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1038\/nature05487","article-title":"Mechanisms linking obesity with cardiovascular disease","volume":"444","author":"Van Gaal","year":"2006","journal-title":"Nature"},{"issue":"2","key":"2024091609272999100_dgae172-B14","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/rth2.12080","article-title":"The coagulation system in atherothrombosis: implications for new therapeutic strategies","volume":"2","author":"Olie","year":"2018","journal-title":"Res Pract Thromb Haemost"},{"issue":"1","key":"2024091609272999100_dgae172-B15","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1477-9560-2-12","article-title":"Blood coagulation and the risk of atherothrombosis: a complex relationship","volume":"2","author":"Spronk","year":"2004","journal-title":"Thromb J"},{"key":"2024091609272999100_dgae172-B16","doi-asserted-by":"crossref","first-page":"101262","DOI":"10.1016\/j.molmet.2021.101262","article-title":"Hemostatic alterations linked to body fat distribution, fatty liver, and insulin resistance","volume":"53","author":"Horber","year":"2021","journal-title":"Mol Metab"},{"issue":"2","key":"2024091609272999100_dgae172-B17","doi-asserted-by":"crossref","first-page":"e058268","DOI":"10.1136\/bmjopen-2021-058268","article-title":"The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: rationale, methodology and design","volume":"12","author":"Fritsche","year":"2022","journal-title":"BMJ Open"},{"issue":"S 02","key":"2024091609272999100_dgae172-B18","doi-asserted-by":"crossref","first-page":"S196","DOI":"10.1055\/a-0898-9706","article-title":"Gestationsdiabetes mellitus (GDM), diagnostik, therapie und nachsorge\u2014praxisempfehlung\u2014kurzfassung der S3-leitlinie (AWMF-registernummer: 057-008)","volume":"14","author":"Sch\u00e4fer-Graf","year":"2019","journal-title":"Diabetologie und Stoffwechsel"},{"key":"2024091609272999100_dgae172-B19","author":"World Health Organization"},{"issue":"9","key":"2024091609272999100_dgae172-B20","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.2337\/diacare.22.9.1462","article-title":"Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp","volume":"22","author":"Matsuda","year":"1999","journal-title":"Diabetes Care"},{"issue":"6","key":"2024091609272999100_dgae172-B21","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/CIRCULATIONAHA.107.699579","article-title":"General cardiovascular risk profile for use in primary care: the Framingham Heart Study","volume":"117","author":"D\u2019Agostino","year":"2008","journal-title":"Circulation"},{"key":"2024091609272999100_dgae172-B22","author":"Castro"},{"issue":"5","key":"2024091609272999100_dgae172-B23","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1093\/ajcn\/36.5.936","article-title":"A short questionnaire for the measurement of habitual physical activity in epidemiological studies","volume":"36","author":"Baecke","year":"1982","journal-title":"Am J Clin Nutr"},{"issue":"8","key":"2024091609272999100_dgae172-B24","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1080\/14779072.2022.2100761","article-title":"The cardiovascular benefits of breastfeeding to mothers","volume":"20","author":"Tschiderer","year":"2022","journal-title":"Expert Rev Cardiovasc Ther"},{"issue":"5","key":"2024091609272999100_dgae172-B25","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1097\/01.AOG.0000346884.67796.ca","article-title":"Duration of lactation and risk factors for maternal cardiovascular disease","volume":"113","author":"Schwarz","year":"2009","journal-title":"Obstet Gynecol"},{"issue":"9","key":"2024091609272999100_dgae172-B26","doi-asserted-by":"crossref","first-page":"863.e1","DOI":"10.1016\/j.amjmed.2010.03.016","article-title":"Lactation and maternal risk of type 2 diabetes: a population-based study","volume":"123","author":"Schwarz","year":"2010","journal-title":"Am J Med"},{"issue":"2","key":"2024091609272999100_dgae172-B27","doi-asserted-by":"crossref","first-page":"495","DOI":"10.2337\/db09-1197","article-title":"Duration of lactation and incidence of the metabolic syndrome in women of reproductive age according to gestational diabetes mellitus status: a 20-year prospective study in CARDIA (Coronary Artery Risk Development in Young Adults)","volume":"59","author":"Gunderson","year":"2010","journal-title":"Diabetes"},{"issue":"10","key":"2024091609272999100_dgae172-B28","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1093\/aje\/kwr227","article-title":"Duration of lactation and incidence of maternal hypertension: a longitudinal cohort study","volume":"174","author":"Stuebe","year":"2011","journal-title":"Am J Epidemiol"},{"issue":"1","key":"2024091609272999100_dgae172-B29","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/AOG.0b013e3181c5512a","article-title":"Lactation and maternal measures of subclinical cardiovascular disease","volume":"115","author":"Schwarz","year":"2010","journal-title":"Obstet Gynecol"},{"issue":"12","key":"2024091609272999100_dgae172-B30","doi-asserted-by":"crossref","first-page":"3678","DOI":"10.1182\/blood.V95.12.3678.012k45_3678_3682","article-title":"High levels of factor IX increase the risk of venous thrombosis","volume":"95","author":"van Hylckama Vlieg","year":"2000","journal-title":"Blood"},{"issue":"4","key":"2024091609272999100_dgae172-B31","doi-asserted-by":"crossref","first-page":"402","DOI":"10.5551\/jat.3673","article-title":"Coagulation factors II, V, IX, X, XI, and XII, plasminogen, and alpha-2 antiplasmin and risk of coronary heart disease","volume":"17","author":"Yamagishi","year":"2010","journal-title":"J Atheroscler Thromb"},{"issue":"10","key":"2024091609272999100_dgae172-B32","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.2337\/diacare.25.10.1862","article-title":"Gestational diabetes and the incidence of type 2 diabetes: a systematic review","volume":"25","author":"Kim","year":"2002","journal-title":"Diabetes Care"},{"issue":"6","key":"2024091609272999100_dgae172-B33","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00125-019-4840-2","article-title":"Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis","volume":"62","author":"Kramer","year":"2019","journal-title":"Diabetologia"},{"issue":"5","key":"2024091609272999100_dgae172-B34","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3109\/09513590.2010.495241","article-title":"Haemostatic and cytokine changes in gestational diabetes mellitus","volume":"27","author":"Abdel Gader","year":"2011","journal-title":"Gynecol Endocrinol"},{"issue":"2","key":"2024091609272999100_dgae172-B35","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4103\/0974-2727.180790","article-title":"Is there a tendency for thrombosis in gestational diabetes mellitus?","volume":"8","author":"Gorar","year":"2016","journal-title":"J Lab Physicians"},{"issue":"8","key":"2024091609272999100_dgae172-B36","doi-asserted-by":"crossref","first-page":"e3198","DOI":"10.1210\/clinem\/dgab124","article-title":"Lifestyle intervention improves prothrombotic coagulation profile in individuals at high risk for type 2 diabetes","volume":"106","author":"Horber","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2024091609272999100_dgae172-B37","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/jth.13698","article-title":"Associations of coagulation factors IX and XI levels with incident coronary heart disease and ischemic stroke: the REGARDS study","volume":"15","author":"Olson","year":"2017","journal-title":"J Thromb Haemost"},{"issue":"1","key":"2024091609272999100_dgae172-B38","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1600-0609.2006.00656.x","article-title":"Procoagulant factors and the risk of myocardial infarction in young women","volume":"77","author":"Tanis","year":"2006","journal-title":"Eur J Haematol"},{"key":"2024091609272999100_dgae172-B39","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.thromres.2016.02.002","article-title":"Plasminogen activator inhibitor and the risk of cardiovascular disease: the Framingham Heart Study","volume":"140","author":"Tofler","year":"2016","journal-title":"Thromb Res"},{"issue":"8","key":"2024091609272999100_dgae172-B40","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1093\/aje\/kwr203","article-title":"Free protein S level as a risk factor for coronary heart disease and stroke in a prospective cohort study of healthy United Kingdom men","volume":"174","author":"Ken-Dror","year":"2011","journal-title":"Am J Epidemiol"},{"issue":"2","key":"2024091609272999100_dgae172-B41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0049-3848(00)00379-0","article-title":"An association between plasma free protein s concentration and risk of coronary heart disease in middle-aged men","volume":"101","author":"Rudnicka","year":"2001","journal-title":"Thromb Res"},{"issue":"4","key":"2024091609272999100_dgae172-B42","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1182\/blood-2003-05-1551","article-title":"Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S-C4b binding protein complex","volume":"103","author":"Rezende","year":"2004","journal-title":"Blood"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgae172\/57115857\/dgae172.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/109\/10\/2571\/59135830\/dgae172.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/109\/10\/2571\/59135830\/dgae172.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T09:30:28Z","timestamp":1726479028000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/109\/10\/2571\/7629536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,15]]},"references-count":42,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,3,15]]},"published-print":{"date-parts":[[2024,9,16]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgae172","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,10]]},"published":{"date-parts":[[2024,3,15]]}}}