{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:19:35Z","timestamp":1785151175992,"version":"3.55.0"},"reference-count":9,"publisher":"The Endocrine Society","issue":"12","license":[{"start":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:00:00Z","timestamp":1723161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Because of the high mortality rate of thyroid storm (TS), effective guidance for its diagnosis and treatment is essential. The diagnostic criteria introduced by the Japanese Thyroid Association in 2012, along with the Burch-Wartofsky Point Scale, constitute valuable tools for the diagnosis of TS. In 2016, Guidelines on the management of TS were produced by the Japanese Thyroid Association and the Japanese Endocrine Society. Recently, a prospective multicenter register-based study compared the prognosis and outcome of 110 new-onset TS patients with the results of previous comparable studies and evaluated the efficacy of the Guidelines. The study revealed higher Acute Physiology and Chronic Health Evaluation II scores and significant correlations between lower body mass index, postresuscitation shock, and fever with outcomes and, overall, improved TS prognosis. Most patients in the study received methimazole and potassium iodide, the timely administration of which was linked to lower fatality rates. Adherence to treatment guidelines correlates with lower mortality rates, emphasizing the importance of experienced multidisciplinary teams in intensive care unit settings and the necessity for periodic review of the guidelines to enhance therapeutic approaches and reduce mortality.<\/jats:p>","DOI":"10.1210\/clinem\/dgae543","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:40:18Z","timestamp":1723077618000},"page":"e2355-e2357","source":"Crossref","is-referenced-by-count":4,"title":["A Small Opening in the Storm Clouds: Overview of the Registry-based Study on the Management of Thyroid Storm"],"prefix":"10.1210","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9133-4089","authenticated-orcid":false,"given":"Leonidas H","family":"Duntas","sequence":"first","affiliation":[{"name":"Evgenideion Hospital, Unit of Endocrinology, Diabetes, and Metabolism, Thyroid Section, National and Kapodistreian University of Athens , 11528 Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9977-5970","authenticated-orcid":false,"given":"Milos","family":"Zarkovic","sequence":"additional","affiliation":[{"name":"Clinic of Endocrinology, Diabetes and Diseases of Metabolism, Thyroid Department, Faculty of Medicine, University of Belgrade , 11000 Belgrade ,","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2024,8,9]]},"reference":[{"issue":"2","key":"2024111804024913000_dgae543-B1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0889-8529(18)30165-8","article-title":"Life-threatening thyrotoxicosis. Thyroid storm","volume":"22","author":"Burch","year":"1993","journal-title":"Endocrinol Metab Clin North Am"},{"key":"2024111804024913000_dgae543-B2","first-page":"482","volume-title":"Werner & Ingbar's Thyroid","author":"Wartofsky","year":"2021","edition":"11th ed"},{"issue":"7","key":"2024111804024913000_dgae543-B3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1089\/thy.2012.2207.ed1","article-title":"Clinical criteria for the diagnosis of thyroid storm","volume":"22","author":"Wartofsky","year":"2012","journal-title":"Thyroid"},{"issue":"7","key":"2024111804024913000_dgae543-B4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1089\/thy.2011.0334","article-title":"Diagnostic criteria, clinical features, and incidence of thyroid storm based on nationwide surveys","volume":"22","author":"Akamizu","year":"2012","journal-title":"Thyroid"},{"issue":"13","key":"2024111804024913000_dgae543-B5","doi-asserted-by":"crossref","first-page":"e37396","DOI":"10.1097\/MD.0000000000037396","article-title":"Diagnostic criteria and scoring systems for thyroid storm: an evaluation of their utile comparative review","volume":"103","author":"Elendu","year":"2024","journal-title":"Medicine (Baltimore)"},{"issue":"12","key":"2024111804024913000_dgae543-B6","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1507\/endocrj.EJ16-0336","article-title":"2016 guidelines for the management of thyroid storm from The Japan Thyroid Association and Japan Endocrine Society (first edition)","volume":"63","author":"Satoh","year":"2016","journal-title":"Endocr J"},{"key":"2024111804024913000_dgae543-B7","doi-asserted-by":"publisher","first-page":"dgae124","DOI":"10.1210\/clinem\/dgae124","article-title":"Multicenter registry-based study on thyroid storm: the guidelines for the management from Japan are useful","author":"Furukawa","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2024111804024913000_dgae543-B8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1172\/JCI107744","article-title":"Triiodothyronine and thyroxine in hyperthyroidism. Comparison of the acute changes during therapy with antithyroid agents","volume":"54","author":"Abuid","year":"1974","journal-title":"J Clin Invest"},{"issue":"6","key":"2024111804024913000_dgae543-B9","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/cen.12949","article-title":"Treatment and management of thyroid storm: analysis of the nationwide surveys: the taskforce committee of the Japan Thyroid Association and Japan Endocrine Society for the establishment of diagnostic criteria and nationwide surveys for thyroid storm","volume":"84","author":"Isozaki","year":"2016","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgae543\/58892480\/dgae543.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/109\/12\/e2355\/60680480\/dgae543.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/109\/12\/e2355\/60680480\/dgae543.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T04:03:33Z","timestamp":1731902613000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/109\/12\/e2355\/7730519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,9]]},"references-count":9,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,8,9]]},"published-print":{"date-parts":[[2024,11,18]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgae543","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,12]]},"published":{"date-parts":[[2024,8,9]]}}}