{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:47:21Z","timestamp":1787021241010,"version":"build-2736575974"},"reference-count":38,"publisher":"The Endocrine Society","issue":"12","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100021671","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021671","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1R25CA240134"],"award-info":[{"award-number":["1R25CA240134"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Johns Hopkins Institute for Clinical and Translational Research","award":["UL1TR001079"],"award-info":[{"award-number":["UL1TR001079"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Although there is an established improved postoperative outcome for pituitary adenomas (PA) surgically resected at high-volume facilities (HVFs), access to these centers may not be equitable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the racial and socioeconomic differences that lead to unequal distribution of access for PAs at HVFs in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and Patients<\/jats:title>\n                    <jats:p>Retrospective analysis of data from the National Cancer Database from 2004 to 2019 on 57 807 patients with PA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Baseline description of patients treated at HVFs, survival outcomes, and predictors of survival were evaluated in patients with PA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 47.6% (n = 27 523) underwent surgery at a HVF. On multivariable analysis, African-American race [odds ratio (OR): 0.89, P &amp;lt; .001] and Hispanic ethnicity (OR: 0.80, P &amp;lt; .001) had significantly lower odds of having a surgical procedure at a HVF as compared to a reference Caucasian population. Patients from rural locations (OR: 0.79, P = .003; reference = urban); with Medicaid insurance (OR: 0.86, P &amp;lt; .001; reference = private), those with lower income [&amp;lt;$40 227 (OR: 0.93, P = .049); reference = \u2265$63 333], and patients from zip codes with large percentages of adults who did not graduate high school [\u226517.6% (OR: 0.95, P &amp;lt; .001); reference = &amp;lt;6.3%] were significantly less likely to have surgery at a HVF. An increasing trend in access to surgical care at HVFs for PA patients over time was demonstrated [eg, 2005 (OR = 1.10 [0.97-1.26], P = .173) vs 2019 (OR = 1.27 [1.13-1.43], P &amp;lt; .001)].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There are significant racial and socioeconomic disparities in access to HVFs for adult patients seeking surgical resection of pituitary adenomas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgaf212","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T07:49:58Z","timestamp":1743493798000},"page":"e4188-e4195","source":"Crossref","is-referenced-by-count":3,"title":["Characterizing Disparities in Access to Surgery for Pituitary Adenomas: A National Cancer Database Analysis"],"prefix":"10.1210","volume":"110","author":[{"given":"Miguel 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