{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T12:30:28Z","timestamp":1791721828446,"version":"4.3.4"},"reference-count":66,"publisher":"The Endocrine Society","issue":"2","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Several studies have investigated whether patients with nonfunctioning adrenal incidentalomas (NFAI) have an increased cardiometabolic risk, based on surrogate parameters such as the augmentation index (Aix), carotid intima-media thickness (cIMT), flow-mediated dilation (FMD), insulin resistance (IR), left ventricular mass index (LVMI), and pulse wave velocity (PWV), compared to patients without adrenal incidentalomas (AI). We sought to analyze the available literature to evaluate AIx, cIMT, FMD, IR, LVMI, and PWV in patients with NFAI as compared to patients without AI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included studies that evaluated the cIMT and IR (primary outcomes) and AIx, FMD, LVMI, and PWV (secondary outcomes) in patients with NFAI vs matched subjects without AI. A random-effects model (DerSimonian and Laird) was used to calculate the standardized mean difference and 95% CI for each outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 24 available studies, 21 studies provided the necessary data (2228 subjects, mean age 53.3 \u00b1 2.9 years, 35% males). Data on cIMT, IR, AIx, FMD, LVMI, and PWV were reported in 12 (1063 subjects), 15 (1745 subjects), 2 (140 subjects), 3 (198 subjects), 3 (201 subjects), and 2 (140 subjects) studies, respectively. Compared with patients without AI, patients with NFAI showed statistically significant differences in cIMT, IR, AIx, FMD, LVMI, and PWV (standardized mean difference and 95% CI: 1.22, 0.87-1.58; 0.51, 0.32-0.69; 0.94, 0.38-1.50; -1.24, -1.84- -0.65; 0.41, 0.04-0.78; 1.03, 0.16-1.89, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Based on cIMT, IR, AIx, FMD, LVMI, and PWV levels, patients with NFAI may be at increased cardiovascular risk<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgaf597","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:13:50Z","timestamp":1761743630000},"page":"e619-e629","source":"Crossref","is-referenced-by-count":6,"title":["Cardiometabolic Risk Parameters in \u201cNonfunctioning\u201d Adrenal Incidentalomas: A Systematic Review and Meta-analysis"],"prefix":"10.1210","volume":"111","author":[{"given":"Vittoria","family":"Favero","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology and Translational Medicine, University of Milan , 20100 Milan ,","place":["Italy"]},{"name":"Unit of Endocrinology, ASST Grande Ospedale Metropolitano Niguarda , 20163 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Bernasconi","sequence":"additional","affiliation":[{"name":"Bicocca Bioinformatics Biostatistics and Bioimaging B4 Center, Department of Medicine and Surgery, University of Milano-Bicocca , 20126 Monza ,","place":["Italy"]},{"name":"Unit of Clinical Research and Innovation, ASST Grande Ospedale Metropolitano Niguarda , 20163 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Maloberti","sequence":"additional","affiliation":[{"name":"School of Medicine and Surgery, University of Milano-Bicocca , 20126 Milan ,","place":["Italy"]},{"name":"Unit of Cardiology-Diagnostic and Rehabilitative, ASST Grande Ospedale Metropolitano Niguarda , 20163 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Parazzoli","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Translational Medicine, University of Milan , 20100 Milan ,","place":["Italy"]},{"name":"Unit of Endocrinology, ASST Grande Ospedale Metropolitano Niguarda , 20163 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Musolino","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Translational Medicine, University of Milan , 20100 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Chilton","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Texas Health Science Center - San Antonio , San Antonio, TX 78299 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony P","family":"Heaney","sequence":"additional","affiliation":[{"name":"Department of Medicine, Endocrinology, University of California , Los Angeles, Los Angeles, CA 90095 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Eller-Vainicher","sequence":"additional","affiliation":[{"name":"Unit of Endocrinology, Fondazione IRCCS C\u00e0 Granda Ospedale Maggiore Policlinico , 20122 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Scillitani","sequence":"additional","affiliation":[{"name":"Unit of Endocrinology, Ospedale \u201cCasa Sollievo Della Sofferenza\u201d , 71013 Foggia 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\u201cCardiometabolic Risk Parameters in \u201cNonfunctioning\u201d Adrenal Incidentalomas: A Systematic Review and Meta-analysis\u201d. 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