{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:32:09Z","timestamp":1791232329946,"version":"4.1.0"},"reference-count":48,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:00:00Z","timestamp":1766448000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Thyroid disease has been reported as a complication associated with acute SARS-CoV-2 infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluated the long-term risk of incident thyroid dysfunction after COVID-19 in patients without preexisting thyroid disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients without prior thyroid disease were grouped into 15 372 individuals hospitalized with COVID-19, 41\u2005757 nonhospitalized individuals with COVID-19, 343\u2005348 contemporary COVID-negative controls (March 1, 2020-August 17, 2024), and 171 141 historical controls (January 1, 2016-December 31, 2019) within the Montefiore Health System. Outcomes included new-onset thyroid disease, hypothyroidism, hyperthyroidism, and other\/unspecified thyroid disease, and thyrotropin (TSH), free 3,5,3\u2032-triiodothyronine (FT3), and free thyroxine (FT4) levels. The primary analysis used Cox regression with inverse probability weighting (IPW). Sensitivity analyses included multivariate adjustment, 1:1 propensity score matching, and comparisons with historical controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared to contemporary COVID-negative controls, patients hospitalized for COVID-19 had significantly higher risk of all thyroid disease (IPW-adjusted hazard ratio (HR)\u202f=\u202f2.11 [2.03-2.19]), hypothyroidism (HR\u202f=\u202f2.02 [1.92-2.12]), hyperthyroidism (HR\u202f=\u202f2.31 [2.13-2.50]), and other\/unspecified thyroid disease (HR\u202f=\u202f2.27 [2.12-2.43]). Nonhospitalized COVID-positive patients also had increased risk of all thyroid disease (HR\u202f=\u202f1.40 [1.35-1.46]), hypothyroidism (HR\u202f=\u202f1.37 [1.31-1.43]), hyperthyroidism (HR\u202f=\u202f1.56 [1.45-1.68]), and other\/unspecified thyroid disease (HR\u202f=\u202f1.42 [1.34-1.51]). Sensitivity analyses were consistent with the main findings. Estimates of risks were attenuated in the nonhospitalized cohort when compared to historical controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SARS-CoV-2 infection is associated with an increased risk of all forms of new-onset thyroid disease investigated both in hospitalized and nonhospitalized patients. These findings suggest that enhanced screening for thyroid dysfunction may be warranted among individuals recovering from COVID-19.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgaf688","type":"journal-article","created":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T12:55:48Z","timestamp":1766235348000},"page":"e1583-e1594","source":"Crossref","is-referenced-by-count":3,"title":["Elevated Risk of New-Onset Thyroid Disease Associated With SARS-CoV-2 Infection: A 4.5-Year Observational Study"],"prefix":"10.1210","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0748-3514","authenticated-orcid":false,"given":"Shiv","family":"Mehrotra-Varma","sequence":"first","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roham","family":"Hadidchi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonya S","family":"Henry","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hien Quang","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai","family":"Mehrotra-Varma","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C","family":"Coard","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagar","family":"Changela","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessilin","family":"Collins","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6403-2827","authenticated-orcid":false,"given":"Tim Q","family":"Duong","sequence":"additional","affiliation":[{"name":"Department of Radiology, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]},{"name":"Center for Health Data Innovation, Montefiore Health System and Albert Einstein College of Medicine , Bronx, NY 10461 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2025,12,23]]},"reference":[{"key":"2026051819580508200_dgaf688-B1","doi-asserted-by":"crossref","first-page":"1126637","DOI":"10.3389\/fendo.2023.1126637","article-title":"Subacute thyroiditis following COVID-19: a systematic review","volume":"14","author":"Meftah","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2026051819580508200_dgaf688-B2","doi-asserted-by":"crossref","first-page":"1535169","DOI":"10.3389\/fendo.2025.1535169","article-title":"Thyroid disorders and COVID-19: a comprehensive review of literature","volume":"16","author":"Anbardar","year":"2025","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"2026051819580508200_dgaf688-B3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s40336-021-00419-y","article-title":"Prevalence of thyroid dysfunction in patients with COVID-19: a systematic review","volume":"9","author":"Giovanella","year":"2021","journal-title":"Clin Transl Imaging"},{"key":"2026051819580508200_dgaf688-B4","doi-asserted-by":"crossref","first-page":"633097","DOI":"10.3389\/fendo.2021.633097","article-title":"Commentary: euthyroid sick syndrome in patients with COVID-19","volume":"12","author":"Laurino","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"2026051819580508200_dgaf688-B5","first-page":"58","article-title":"Thyroid function during and after COVID-19 infection: a review","volume":"18","author":"\u00c7abuk","year":"2022","journal-title":"Endocrinology"},{"issue":"1","key":"2026051819580508200_dgaf688-B6","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1186\/s12879-025-10518-0","article-title":"Subacute thyroiditis as a post-COVID-19 complication: a systematic review","volume":"25","author":"Ghafourian","year":"2025","journal-title":"BMC Infect Dis"},{"issue":"5","key":"2026051819580508200_dgaf688-B7","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1007\/s40618-020-01436-w","article-title":"Detection of SARS-COV-2 receptor ACE-2 mRNA in thyroid cells: a clue for COVID-19-related subacute thyroiditis","volume":"44","author":"Rotondi","year":"2021","journal-title":"J Endocrinol Invest"},{"issue":"3","key":"2026051819580508200_dgaf688-B8","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/s12020-021-02807-w","article-title":"Modulation of ACE-2 mRNA by inflammatory cytokines in human thyroid cells: a pilot study","volume":"74","author":"Coperchini","year":"2021","journal-title":"Endocrine"},{"issue":"4","key":"2026051819580508200_dgaf688-B9","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3803\/EnM.2023.1711","article-title":"Beyond acute COVID-19: investigating the incidence of subacute thyroiditis in long COVID-19 in Korea","volume":"38","author":"Lee","year":"2023","journal-title":"Endocrinology and Metabolism"},{"key":"2026051819580508200_dgaf688-B10","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.2147\/DDDT.S475005","article-title":"Cytokine storm-induced thyroid dysfunction in COVID-19: insights into pathogenesis and therapeutic approaches","volume":"18","author":"Attiq","year":"2024","journal-title":"Drug Des Devel Ther"},{"key":"2026051819580508200_dgaf688-B11","doi-asserted-by":"crossref","first-page":"1477389","DOI":"10.3389\/fendo.2024.1477389","article-title":"Thyroid function during COVID-19 and post-COVID complications in adults: a systematic review","volume":"15","author":"Panesar","year":"2025","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2026051819580508200_dgaf688-B12","doi-asserted-by":"crossref","first-page":"1412320","DOI":"10.3389\/fendo.2024.1412320","article-title":"Thyroid dysfunction in the wake of omicron: understanding its role in COVID-19 severity and mortality","volume":"15","author":"Zhang","year":"2024","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2026051819580508200_dgaf688-B13","doi-asserted-by":"crossref","first-page":"102314","DOI":"10.1016\/j.tmaid.2022.102314","article-title":"Systematic review of COVID-19 and autoimmune thyroiditis","volume":"47","author":"Tutal","year":"2022","journal-title":"Travel Med Infect Dis"},{"issue":"1","key":"2026051819580508200_dgaf688-B14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s43168-025-00366-6","article-title":"Impact of covid-19 infection on thyroid functions","volume":"19","author":"Hamed","year":"2025","journal-title":"Egyptian J Bronchol"},{"issue":"16","key":"2026051819580508200_dgaf688-B15","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1016\/j.jacc.2018.02.045","article-title":"Thyroid hormones and cardiovascular function and diseases","volume":"71","author":"Razvi","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"2026051819580508200_dgaf688-B16","doi-asserted-by":"crossref","first-page":"76","DOI":"10.2174\/1874192401105010076","article-title":"Effects of thyroid dysfunction on lipid profile","volume":"5","author":"Rizos","year":"2011","journal-title":"Open Cardiovasc Med J"},{"issue":"3","key":"2026051819580508200_dgaf688-B17","doi-asserted-by":"crossref","first-page":"e12948","DOI":"10.1111\/jne.12948","article-title":"The relation between thyroid dysregulation and impaired cognition\/behaviour: an integrative review","volume":"33","author":"Eslami-Amirabadi","year":"2021","journal-title":"J Neuroendocrinol"},{"key":"2026051819580508200_dgaf688-B18","first-page":"100041","article-title":"Clinical characteristics of the first and second COVID-19 waves in the Bronx, New York: a retrospective cohort study","volume":"3","author":"Hoogenboom","year":"2021","journal-title":"Lancet Reg Health Am"},{"key":"2026051819580508200_dgaf688-B19","doi-asserted-by":"crossref","first-page":"104487","DOI":"10.1016\/j.ebiom.2023.104487","article-title":"Incidence of new-onset in-hospital and persistent diabetes in COVID-19 patients: comparison with influenza","volume":"90","author":"Lu","year":"2023","journal-title":"EBioMedicine"},{"issue":"1","key":"2026051819580508200_dgaf688-B20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s15010-021-01646-1","article-title":"Longitudinal prediction of hospital-acquired acute kidney injury in COVID-19: a two-center study","volume":"50","author":"Lu","year":"2022","journal-title":"Infection"},{"key":"2026051819580508200_dgaf688-B21","doi-asserted-by":"crossref","first-page":"103821","DOI":"10.1016\/j.ebiom.2022.103821","article-title":"Clinical predictors of acute cardiac injury and normalization of troponin after hospital discharge from COVID-19","volume":"76","author":"Lu","year":"2022","journal-title":"EBioMedicine"},{"key":"2026051819580508200_dgaf688-B22","doi-asserted-by":"crossref","first-page":"105778","DOI":"10.1016\/j.ebiom.2025.105778","article-title":"Long-term outcomes of patients with pre-existing coronary artery disease after SARS-CoV-2 infection","volume":"116","author":"Hadidchi","year":"2025","journal-title":"EBioMedicine"},{"issue":"8","key":"2026051819580508200_dgaf688-B23","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1016\/j.jaip.2025.05.010","article-title":"Longer-term effects of SARS-CoV-2 infection on asthma exacerbation","volume":"13","author":"Duong","year":"2025","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"9","key":"2026051819580508200_dgaf688-B24","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1111\/dom.15120","article-title":"Incidence, characteristics, risk factors and outcomes of diabetic ketoacidosis in COVID-19 patients: comparison with influenza and pre-pandemic data","volume":"25","author":"Dell'Aquila","year":"2023","journal-title":"Diabetes Obes Metab"},{"issue":"4","key":"2026051819580508200_dgaf688-B25","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1007\/s12072-021-10228-0","article-title":"Longitudinal progression of clinical variables associated with graded liver injury in COVID-19 patients","volume":"15","author":"Lu","year":"2021","journal-title":"Hepatol Int"},{"issue":"10","key":"2026051819580508200_dgaf688-B26","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1093\/ndt\/gfad020","article-title":"Long-term outcomes of COVID-19 survivors with hospital AKI: association with time to recovery from AKI","volume":"38","author":"Lu","year":"2023","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"2026051819580508200_dgaf688-B27","doi-asserted-by":"crossref","first-page":"e0303151","DOI":"10.1371\/journal.pone.0303151","article-title":"Incidence, characteristics, and risk factors of new liver disorders 3.5 years post COVID-19 pandemic in the Montefiore health system in Bronx","volume":"19","author":"Peng","year":"2024","journal-title":"PLoS One"},{"issue":"10","key":"2026051819580508200_dgaf688-B28","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1161\/HYPERTENSIONAHA.123.21174","article-title":"Incidence of new-onset hypertension post-COVID-19: comparison with influenza","volume":"80","author":"Zhang","year":"2023","journal-title":"Hypertension"},{"issue":"9","key":"2026051819580508200_dgaf688-B29","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.3390\/diagnostics15091091","article-title":"SARS-CoV-2 infection is associated with an accelerated eGFR decline in kidney transplant recipients up to four years post infection","volume":"15","author":"Qiu","year":"2025","journal-title":"Diagnostics"},{"key":"2026051819580508200_dgaf688-B30","doi-asserted-by":"crossref","first-page":"105613","DOI":"10.1016\/j.msard.2024.105613","article-title":"SARS-CoV-2 infection increases long-term multiple sclerosis disease activity and all-cause mortality in an underserved inner-city population","volume":"86","author":"Hadidchi","year":"2024","journal-title":"Mult Scler Relat Disord"},{"issue":"24","key":"2026051819580508200_dgaf688-B31","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.3390\/diagnostics14242774","article-title":"Long-term outcomes of patients with pre-existing essential tremor after SARS-CoV-2 infection","volume":"14","author":"Pakan","year":"2024","journal-title":"Diagnostics"},{"key":"2026051819580508200_dgaf688-B32","doi-asserted-by":"crossref","first-page":"123477","DOI":"10.1016\/j.jns.2025.123477","article-title":"Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection","volume":"473","author":"Hadidchi","year":"2025","journal-title":"J Neurol Sci"},{"issue":"2","key":"2026051819580508200_dgaf688-B33","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1177\/13872877241303934","article-title":"Long COVID-19 outcomes of patients with pre-existing dementia","volume":"103","author":"Hadidchi","year":"2025","journal-title":"J Alzheimers Dis"},{"issue":"5","key":"2026051819580508200_dgaf688-B34","doi-asserted-by":"crossref","first-page":"e70013","DOI":"10.1111\/ene.70013","article-title":"Impact of COVID-19 on long-term outcomes in Parkinson\u2019s disease","volume":"32","author":"Hadidchi","year":"2025","journal-title":"Eur J Neurol"},{"issue":"1","key":"2026051819580508200_dgaf688-B35","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1186\/s12967-025-06625-w","article-title":"Elevated risk of new-onset chronic fatigue syndrome\/myalgic encephalomyelitis up to four years after SARS-CoV-2 infection","volume":"23","author":"Hadidchi","year":"2025","journal-title":"J Transl Med"},{"issue":"2","key":"2026051819580508200_dgaf688-B36","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10549-025-07713-7","article-title":"COVID-19 pandemic interruption of breast cancer screening is linked to clinical upstaging at presentation: the roles of demographics, socioeconomic status and unmet social needs","volume":"212","author":"Hadidchi","year":"2025","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"2026051819580508200_dgaf688-B37","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1080\/13102818.2023.2170829","article-title":"Thyroid dysfunction as a long-term post-COVID-19 complication in mild-to-moderate COVID-19","volume":"37","author":"Yanachkova","year":"2023","journal-title":"Biotechnol Biotechnol Equip"},{"issue":"11","key":"2026051819580508200_dgaf688-B38","doi-asserted-by":"crossref","first-page":"5368","DOI":"10.1111\/dom.15900","article-title":"Patients with type 1 diabetes are at elevated risk of developing new hypertension, chronic kidney disease and diabetic ketoacidosis after COVID-19: up to 40 months\u2019 follow-up","volume":"26","author":"Mehrotra-Varma","year":"2024","journal-title":"Diabetes Obes Metab"},{"issue":"1","key":"2026051819580508200_dgaf688-B39","doi-asserted-by":"crossref","first-page":"8816198","DOI":"10.1155\/jdr\/8816198","article-title":"Patients with type 2 diabetes are at greater risk of developing new hypertension and chronic kidney disease following COVID-19","volume":"2025","author":"Lu","year":"2025","journal-title":"J Diabetes Res"},{"issue":"1","key":"2026051819580508200_dgaf688-B40","doi-asserted-by":"crossref","first-page":"6119","DOI":"10.1038\/s41598-025-90153-6","article-title":"Long term outcomes of patients with chronic kidney disease after COVID-19 in an urban population in the Bronx","volume":"15","author":"Lu","year":"2025","journal-title":"Sci Rep"},{"issue":"1","key":"2026051819580508200_dgaf688-B41","doi-asserted-by":"crossref","first-page":"28728","DOI":"10.1038\/s41598-025-14617-5","article-title":"Incidence and risk factors of new-onset hypertension up to 3 years post SARS-CoV-2 infection","volume":"15","author":"Boparai","year":"2025","journal-title":"Sci Rep"},{"issue":"6","key":"2026051819580508200_dgaf688-B42","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.eprac.2024.03.389","article-title":"Risk of incident thyroid dysfunction in the post-acute phase of COVID-19: a population-based cohort study in Hong Kong","volume":"30","author":"Lui","year":"2024","journal-title":"Endocr Pract"},{"issue":"2","key":"2026051819580508200_dgaf688-B43","doi-asserted-by":"crossref","first-page":"e220200","DOI":"10.1530\/ETJ-22-0200","article-title":"Long-term outcome of thyroid abnormalities in patients with severe covid-19","volume":"12","author":"Muller","year":"2023","journal-title":"Eur Thyroid J"},{"key":"2026051819580508200_dgaf688-B44","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.2147\/IJGM.S366784","article-title":"Management of subacute thyroiditis\u2014a systematic review of current treatment protocols","volume":"15","author":"Ray","year":"2022","journal-title":"Int J Gen Med"},{"key":"2026051819580508200_dgaf688-B45","doi-asserted-by":"crossref","first-page":"1384365","DOI":"10.3389\/fendo.2024.1384365","article-title":"Comparison of treatment outcome between glucocorticoids and non-steroidal anti-inflammatory drugs in subacute thyroiditis patients\u2014a systematic review and meta-analysis","volume":"15","author":"Yuan","year":"2024","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"2026051819580508200_dgaf688-B46","doi-asserted-by":"crossref","first-page":"5446","DOI":"10.1038\/s41598-024-55526-3","article-title":"Occult endocrine disorders newly diagnosed in patients with post-COVID-19 symptoms","volume":"14","author":"Nakano","year":"2024","journal-title":"Sci Rep"},{"issue":"1","key":"2026051819580508200_dgaf688-B47","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1210\/er.2006-0043","article-title":"The clinical significance of subclinical thyroid dysfunction","volume":"29","author":"Biondi","year":"2008","journal-title":"Endocr Rev"},{"key":"2026051819580508200_dgaf688-B48","unstructured":"Hadidchi R . hadidchi\/CAD-COVID-19: v1.0.0. Zenodo; 2025."}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgaf688\/66118470\/dgaf688.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/111\/6\/e1583\/66118470\/dgaf688.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/111\/6\/e1583\/66118470\/dgaf688.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T23:58:17Z","timestamp":1779148697000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/111\/6\/e1583\/8403187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,23]]},"references-count":48,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,12,23]]},"published-print":{"date-parts":[[2026,5,19]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgaf688","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2025,12,23]]}}}