{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:24:40Z","timestamp":1790267080976,"version":"4.1.0"},"reference-count":59,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Regional Agreement on Medical Training and Clinical Research"},{"DOI":"10.13039\/501100011727","name":"Stockholm County Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Region V\u00e4rmland's County Research Council"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>The effect of autoimmune Addison's disease (AAD) on work ability and income over time remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This work aimed to evaluate differences and temporal trends in income and lost workdays among patients with AAD before and after diagnosis, vs matched general population comparators. This nationwide, register-based cohort study was conducted in Sweden. We linked the Swedish Addison Register with national health registers to identify 716 working-age individuals (aged 20-62 years) with incident AAD 2003 to 2019 and 3271 general-population comparators matched by sex, age, county, calendar year, and education level. Annual work loss, taxable earnings, and disposable income were examined over a 10-year period around diagnosis using linear (work loss) and quantile (earnings, income) regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients with AAD had significantly more work loss than comparators from 1 year before to 3 years after diagnosis, with the largest difference the year after diagnosis (mean difference: 30.5 days; 95% CI, 22.9-38.0 days). Median taxable earnings were lower in patients with AAD 1 year before (median difference: $\u22121107; 95% CI, $\u22122042 to $\u2212173; P = .02) and 1 year after diagnosis ($\u22121105; 95% CI, $\u22122166 to $\u221243; P = .04). Disposable income was also reduced 1 year after diagnosis (median difference: $\u22121084; 95% CI, $\u22121813 to $\u2212354; P = .004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In AAD, increased work loss and reduced earnings and income were concentrated around diagnosis, peaking in the year after. Reassuringly, both absence from work and income normalized within 4 years following diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgaf696","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T12:44:02Z","timestamp":1766839442000},"page":"e1562-e1572","source":"Crossref","is-referenced-by-count":2,"title":["Work Loss and Income Before and After Diagnosis of Addison's Disease: A Population-Based Longitudinal Study"],"prefix":"10.1210","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3476-3287","authenticated-orcid":false,"given":"Stavros","family":"Stergianos","sequence":"first","affiliation":[{"name":"Department of Medicine, Solna, Division of Experimental Endocrinology, Karolinska Institutet , Stockholm SE-171 76 ,","place":["Sweden"]},{"name":"Department of Endocrinology, Karolinska University Hospital , Stockholm SE-171 76 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