{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:49:13Z","timestamp":1790790553103,"version":"4.1.0"},"reference-count":40,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100024253","name":"Future Health Research and Innovation Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100024253","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022560","name":"Spinnaker Health Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022560","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["003209"],"award-info":[{"award-number":["003209"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["211912"],"award-info":[{"award-number":["211912"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["403968"],"award-info":[{"award-number":["403968"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["634445"],"award-info":[{"award-number":["634445"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["353514"],"award-info":[{"award-number":["353514"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["403981"],"award-info":[{"award-number":["403981"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["634445"],"award-info":[{"award-number":["634445"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1102106"],"award-info":[{"award-number":["1102106"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1109057"],"award-info":[{"award-number":["1109057"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001202","name":"Gastroenterological Society of Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001202","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fremantle Hospital"},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation","doi-asserted-by":"publisher","award":["102301"],"award-info":[{"award-number":["102301"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation","doi-asserted-by":"publisher","award":["1147677"],"award-info":[{"award-number":["1147677"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012505","name":"Royal Perth Hospital Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012505","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002996","name":"Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"publisher"}]},{"name":"WA Branch"},{"DOI":"10.13039\/501100022177","name":"Lions Eye Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022177","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018548","name":"Curtin University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018548","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001801","name":"University of Western Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>In women in their reproductive years, metabolic dysfunction-associated steatotic liver disease (MASLD) and polycystic ovary syndrome (PCOS) are the most common chronic liver and endocrine disorders, respectively. MASLD and PCOS are associated with longer-term risk of cardiometabolic complications. We aimed to determine whether PCOS coexisting with MASLD (PCOS + MASLD) predicts greater risk of future cardiometabolic adverse parameters than either condition alone after 10 years in a longitudinal study of adolescents in the Raine Study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A total of 199 community-based female adolescents participating in the Raine Study had assessments for both PCOS and MASLD, including anthropometry, blood tests, and pelvic and abdominal ultrasound. Using updated diagnostic criteria, diagnoses of PCOS at age 14 years and MASLD at age 17 years, were retrospectively determined. At age 27 years, 148 participants had further anthropometry and cardiovascular and fasting blood assessments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At age 17 years, 37 (18.6%) had MASLD, 32 (16.1%) had PCOS, 20 (10.1%) had PCOS without MASLD, and 142 (71.4%) had neither. Among adolescents with PCOS, 12\/32 (37.5%) had PCOS + MASLD, associated with obesity, higher serum remnant lipoprotein cholesterol, and free and total testosterone, but lower SHBG, compared with those with only MASLD, PCOS, or neither (P &amp;lt; .05 for all). By age 27 years, those with PCOS + MASLD (10\/148) during adolescence were more insulin resistant and had higher serum remnant lipoprotein cholesterol and triglyceride\/high-density lipoprotein cholesterol ratio (P &amp;lt; .05 for all), compared with those with only PCOS or MASLD or neither. PCOS without MASLD or obesity in adolescence did not predict future insulin resistance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PCOS + MASLD in adolescents, but not PCOS alone, increases the likelihood of obesity, insulin resistance and an adverse cardiometabolic phenotype during adulthood.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgag008","type":"journal-article","created":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T12:31:36Z","timestamp":1768134696000},"page":"e1485-e1492","source":"Crossref","is-referenced-by-count":2,"title":["MASLD coexisting with PCOS increases cardiometabolic risk"],"prefix":"10.1210","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0598-151X","authenticated-orcid":false,"given":"Oyekoya T","family":"Ayonrinde","sequence":"first","affiliation":[{"name":"Medical School, The University of Western Australia , Nedlands, WA 6009 ,","place":["Australia"]},{"name":"Department of Gastroenterology and Hepatology, Fiona Stanley Hospital , Murdoch, WA 6150 ,","place":["Australia"]},{"name":"Medical School, Curtin University , Bentley, WA 6102 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor A","family":"Mori","sequence":"additional","affiliation":[{"name":"Medical School, The University of Western Australia , Nedlands, WA 6009 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon A","family":"Adams","sequence":"additional","affiliation":[{"name":"Medical School, The University of Western Australia , Nedlands, WA 6009 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4853-7360","authenticated-orcid":false,"given":"Lawrence J","family":"Beilin","sequence":"additional","affiliation":[{"name":"Medical School, The University of Western Australia , Nedlands, WA 6009 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K","family":"Olynyk","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Fiona Stanley Hospital , Murdoch, WA 6150 ,","place":["Australia"]},{"name":"Curtin Medical Research Institute, Curtin University , Bentley, WA 6102 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6610-3040","authenticated-orcid":false,"given":"Roger","family":"Hart","sequence":"additional","affiliation":[{"name":"Medical School, The University of Western Australia , Nedlands, WA 6009 ,","place":["Australia"]},{"name":"Department of Obstetrics and Gynaecology, King Edward Memorial Hospital , Subiaco, WA 6008 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2026,1,13]]},"reference":[{"issue":"3","key":"2026051819582803300_dgag008-B1","doi-asserted-by":"crossref","first-page":"R145","DOI":"10.1530\/EJE-16-1063","article-title":"Management of endocrine disease: polycystic ovary syndrome and nonalcoholic fatty liver disease","volume":"177","author":"Macut","year":"2017","journal-title":"Eur J Endocrinol"},{"issue":"6","key":"2026051819582803300_dgag008-B2","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1097\/HEP.0000000000000520","article-title":"A multisociety Delphi consensus statement on new fatty liver disease nomenclature","volume":"78","author":"Rinella","year":"2023","journal-title":"Hepatology"},{"issue":"4","key":"2026051819582803300_dgag008-B3","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1097\/HEP.0000000000000004","article-title":"The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review","volume":"77","author":"Younossi","year":"2023","journal-title":"Hepatology"},{"issue":"9","key":"2026051819582803300_dgag008-B4","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S2468-1253(22)00165-0","article-title":"The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis","volume":"7","author":"Riazi","year":"2022","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"3","key":"2026051819582803300_dgag008-B5","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1002\/hep.24097","article-title":"Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease","volume":"53","author":"Ayonrinde","year":"2011","journal-title":"Hepatology"},{"issue":"2","key":"2026051819582803300_dgag008-B6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/jgh.15723","article-title":"Impact of renaming NAFLD to MAFLD in an Australian regional cohort: results from a prospective population-based study","volume":"37","author":"Kemp","year":"2022","journal-title":"J Gastroenterol Hepatol"},{"key":"2026051819582803300_dgag008-B7","author":"Australian Institute of Health and Welfare"},{"issue":"6","key":"2026051819582803300_dgag008-B8","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1007\/s12325-017-0556-1","article-title":"NAFLD as a sexual dimorphic disease: role of gender and reproductive status in the development and progression of nonalcoholic fatty liver disease and inherent cardiovascular risk","volume":"34","author":"Ballestri","year":"2017","journal-title":"Adv Ther"},{"issue":"9","key":"2026051819582803300_dgag008-B9","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1007\/s40618-022-01766-x","article-title":"Non-alcoholic fatty liver disease through the female lifespan: the role of sex hormones","volume":"45","author":"Pafili","year":"2022","journal-title":"J Endocrinol Invest"},{"issue":"2","key":"2026051819582803300_dgag008-B10","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/humrep\/dep399","article-title":"The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria","volume":"25","author":"March","year":"2010","journal-title":"Hum Reprod"},{"issue":"11","key":"2026051819582803300_dgag008-B11","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.3390\/ijerph15112589","article-title":"Geographical prevalence of polycystic ovary syndrome as determined by region and race\/ethnicity","volume":"15","author":"Wolf","year":"2018","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"2026051819582803300_dgag008-B12","doi-asserted-by":"crossref","first-page":"39.e1","DOI":"10.1016\/j.ajog.2023.04.010","article-title":"Incidence, prevalence, and trends in polycystic ovary syndrome diagnosis: a United States population-based study from 2006 to 2019","volume":"229","author":"Yu","year":"2023","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"2026051819582803300_dgag008-B13","doi-asserted-by":"crossref","first-page":"G43","DOI":"10.1093\/ejendo\/lvad096","article-title":"Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome","volume":"189","author":"Teede","year":"2023","journal-title":"Eur J Endocrinol"},{"issue":"9","key":"2026051819582803300_dgag008-B14","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1093\/humrep\/dey256","article-title":"Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome","volume":"33","author":"Teede","year":"2018","journal-title":"Hum Reprod"},{"issue":"8","key":"2026051819582803300_dgag008-B15","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.3390\/diagnostics12081931","article-title":"Criteria for diagnosis of polycystic ovary syndrome during adolescence: literature review","volume":"12","author":"Pe\u00f1a","year":"2022","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"2026051819582803300_dgag008-B16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1186\/s12916-020-01861-x","article-title":"Updated adolescent diagnostic criteria for polycystic ovary syndrome: impact on prevalence and longitudinal body mass index trajectories from birth to adulthood","volume":"18","author":"Tay","year":"2020","journal-title":"BMC Med"},{"issue":"2","key":"2026051819582803300_dgag008-B17","first-page":"173","article-title":"Impact of updated international diagnostic criteria for the diagnosis of polycystic ovary syndrome","volume":"4","author":"Kostroun","year":"2022","journal-title":"F S Rep"},{"issue":"1","key":"2026051819582803300_dgag008-B18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ecl.2020.10.002","article-title":"Diagnosis of polycystic ovary syndrome: which criteria to use and when?","volume":"50","author":"Chang","year":"2021","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"7","key":"2026051819582803300_dgag008-B19","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/j.fertnstert.2011.03.001","article-title":"Extent of metabolic risk in adolescent girls with features of polycystic ovary syndrome","volume":"95","author":"Hart","year":"2011","journal-title":"Fertil Steril"},{"issue":"9","key":"2026051819582803300_dgag008-B20","doi-asserted-by":"crossref","first-page":"e3369","DOI":"10.1210\/clinem\/dgab392","article-title":"Women with polycystic ovary syndrome have an increased risk of major cardiovascular events: a population study","volume":"106","author":"Berni","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"2026051819582803300_dgag008-B21","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/jgh.13241","article-title":"Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys","volume":"31","author":"Ayonrinde","year":"2016","journal-title":"J Gastroenterol Hepatol"},{"issue":"5","key":"2026051819582803300_dgag008-B22","first-page":"1384","article-title":"Cohort profile: the western Australian pregnancy cohort (raine) study-generation 2","volume":"46","author":"Straker","year":"2017","journal-title":"Int J Epidemiol"},{"issue":"6","key":"2026051819582803300_dgag008-B23","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1093\/humrep\/der102","article-title":"Clinical, ultrasound and biochemical features of polycystic ovary syndrome in adolescents: implications for diagnosis","volume":"26","author":"Hickey","year":"2011","journal-title":"Hum Reprod"},{"issue":"6","key":"2026051819582803300_dgag008-B24","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.eprac.2025.02.013","article-title":"Triglyceride to high-density lipoprotein cholesterol (TG\/HDL-C) ratio as a marker of subclinical coronary atherosclerosis and hepatic steatosis in familial hypercholesterolaemia","volume":"31","author":"Huangfu","year":"2025","journal-title":"Endocr Pract"},{"key":"2026051819582803300_dgag008-B25","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.metabol.2017.09.016","article-title":"Polycystic ovarian syndrome (PCOS): long-term metabolic consequences","volume":"86","author":"Anagnostis","year":"2018","journal-title":"Metabolism"},{"issue":"3","key":"2026051819582803300_dgag008-B26","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1210\/jc.2014-3886","article-title":"The potential implications of a PCOS diagnosis on a woman's long-term health using data linkage","volume":"100","author":"Hart","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2026051819582803300_dgag008-B27","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1093\/ejendo\/lvae125","article-title":"Prevalence and accurate diagnosis of polycystic ovary syndrome in adolescents across world regions: a systematic review and meta-analysis","volume":"191","author":"Neven","year":"2024","journal-title":"Eur J Endocrinol"},{"issue":"1","key":"2026051819582803300_dgag008-B28","doi-asserted-by":"crossref","first-page":"7085","DOI":"10.1038\/s41598-021-86697-y","article-title":"Non-alcoholic fatty liver disease in polycystic ovary syndrome women","volume":"11","author":"Won","year":"2021","journal-title":"Sci Rep"},{"issue":"2","key":"2026051819582803300_dgag008-B29","doi-asserted-by":"crossref","first-page":"627","DOI":"10.2337\/db20-0800","article-title":"Polycystic ovary syndrome and risk of type 2 diabetes, coronary heart disease, and stroke","volume":"70","author":"Zhu","year":"2021","journal-title":"Diabetes"},{"issue":"7","key":"2026051819582803300_dgag008-B30","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.tcm.2019.08.010","article-title":"Polycystic ovary syndrome and cardiometabolic risk: opportunities for cardiovascular disease prevention","volume":"30","author":"Osibogun","year":"2020","journal-title":"Trends Cardiovasc Med"},{"issue":"6","key":"2026051819582803300_dgag008-B31","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1093\/humupd\/dmaa029","article-title":"Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis","volume":"26","author":"Wekker","year":"2020","journal-title":"Hum Reprod Update"},{"issue":"4","key":"2026051819582803300_dgag008-B32","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/cen.14647","article-title":"Natural history of polycystic ovary syndrome: a systematic review of cardiometabolic outcomes from longitudinal cohort studies","volume":"96","author":"Kiconco","year":"2022","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"23","key":"2026051819582803300_dgag008-B33","doi-asserted-by":"crossref","first-page":"33715","DOI":"10.18632\/oncotarget.9553","article-title":"Polycystic ovary syndrome (PCOS) and the risk of coronary heart disease (CHD): a meta-analysis","volume":"7","author":"Zhao","year":"2016","journal-title":"Oncotarget"},{"issue":"6","key":"2026051819582803300_dgag008-B34","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1089\/jwh.2021.0608","article-title":"A systematic review and meta-analysis of the association between polycystic ovary syndrome and coronary artery calcification","volume":"31","author":"Osibogun","year":"2022","journal-title":"J Womens Health (Larchmt)"},{"issue":"8","key":"2026051819582803300_dgag008-B35","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.ultrasmedbio.2024.03.014","article-title":"WFUMB guidelines\/guidance on liver multiparametric ultrasound. Part 2: guidance on liver fat quantification","volume":"50","author":"Ferraioli","year":"2024","journal-title":"Ultrasound Med Biol"},{"issue":"5","key":"2026051819582803300_dgag008-B36","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1210\/jc.2005-2774","article-title":"Nonalcoholic steatohepatitis and nonalcoholic fatty liver disease in young women with polycystic ovary syndrome","volume":"91","author":"Setji","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"2026051819582803300_dgag008-B37","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/ajg.2016.453","article-title":"Age as a confounding factor for the accurate non-invasive diagnosis of advanced NAFLD fibrosis","volume":"112","author":"McPherson","year":"2017","journal-title":"Am J Gastroenterol"},{"issue":"7","key":"2026051819582803300_dgag008-B38","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1016\/j.cgh.2022.10.020","article-title":"Diagnostic performance of noninvasive tests for advanced hepatic fibrosis in young age population","volume":"21","author":"Kim","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"6","key":"2026051819582803300_dgag008-B39","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1097\/AOG.0000000000000852","article-title":"Implications of polycystic ovary syndrome for pregnancy and for the health of offspring","volume":"125","author":"Doherty","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"18","key":"2026051819582803300_dgag008-B40","doi-asserted-by":"crossref","first-page":"5921","DOI":"10.3390\/jcm12185921","article-title":"Semaglutide treatment of excessive body weight in obese PCOS patients unresponsive to lifestyle programs","volume":"12","author":"Carmina","year":"2023","journal-title":"J Clin Med"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgag008\/66382572\/dgag008.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/111\/6\/e1485\/66382572\/dgag008.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/111\/6\/e1485\/66382572\/dgag008.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T23:58:36Z","timestamp":1779148716000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/111\/6\/e1485\/8423537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,13]]},"references-count":40,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,1,13]]},"published-print":{"date-parts":[[2026,5,19]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgag008","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,1,13]]}}}