{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:06:34Z","timestamp":1784073994970,"version":"3.55.0"},"reference-count":53,"publisher":"The Endocrine Society","issue":"8","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["23K15091)"],"award-info":[{"award-number":["23K15091)"]}]},{"DOI":"10.13039\/100031495","name":"Yokoyama Foundation for Clinical Pharmacology","doi-asserted-by":"publisher","award":["YRY-2311"],"award-info":[{"award-number":["YRY-2311"]}],"id":[{"id":"10.13039\/100031495","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare, Japan","doi-asserted-by":"publisher","award":["H29-Nanji-Ippan-046"],"award-info":[{"award-number":["H29-Nanji-Ippan-046"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Adrenal venous sampling (AVS) plays a pivotal role in treatment optimization for primary aldosteronism (PA) to minimize cardiovascular risks. However, technical difficulties often hinder accurate cannulation to the adrenal veins (AVs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to explore the distribution of partial pressure of oxygen (pO2) in the AV and neighboring veins, inspired by our awareness of the lighter red color of adrenal venous blood than the others.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We enrolled 179 PA patients who underwent AVS from 2021 to 2024. During AVS, we collected residual blood samples from bilateral AV, hepatic (HV), inferior phrenic, and external iliac veins for blood gas analysis. Statistical analysis was conducted to evaluate pO2 distributions and its associations with clinical parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 179 patients examined, 168 received oxygen supplementation during AVS and in those cases, the pO2 levels were significantly higher in the bilateral AVs than in the HV and inferior phrenic veins at baseline, whereas the levels of partial pressure of carbon dioxide were lower. Following cosyntropin stimulation, the pO2 levels in the AVs decreased but distribution patterns across the examined veins remained similar. The pO2 evaluation provided highly accurate identification of AVs both before and after cosyntropin stimulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is the first study to examine the pO2 dynamics in the human AV and non-AVs, demonstrating its potential to improve AVS cannulation success rates. Our findings also presented the oxygen consumption in the adrenal glands for steroidogenesis. The pO2 measurement is a faster, easier and less-expensive tool enhancing AVS techniques.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgag089","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T12:47:41Z","timestamp":1772714861000},"page":"2293-2305","source":"Crossref","is-referenced-by-count":1,"title":["Partial pressure of oxygen-guided adrenal venous sampling in primary aldosteronism"],"prefix":"10.1210","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7422-2659","authenticated-orcid":false,"given":"Kei","family":"Omata","sequence":"first","affiliation":[{"name":"Department of Diabetes, Metabolism, and Endocrinology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1546-6949","authenticated-orcid":false,"given":"Yuta","family":"Tezuka","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism, and Endocrinology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromitsu","family":"Tannai","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshikiyo","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism, and Endocrinology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ishihata","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Endodontology, Tohoku University Graduate School of Dentistry , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kamada","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7101-7382","authenticated-orcid":false,"given":"Sota","family":"Oguro","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihide","family":"Kawasaki","sequence":"additional","affiliation":[{"name":"Department of Urology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Urology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuto","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironobu","family":"Sasano","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuhiro","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension, Tohoku University Hospital , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Takase","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1093-3704","authenticated-orcid":false,"given":"Hideki","family":"Katagiri","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism, and Endocrinology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0720-0470","authenticated-orcid":false,"given":"Fumitoshi","family":"Satoh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine , Sendai, Miyagi 980-8575 ,","place":["Japan"]},{"name":"Department of Nephrology and Hypertension, Tohoku University Hospital , Sendai, Miyagi 980-8575 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"issue":"11","key":"2026071419575246200_dgag089-B1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/s41574-022-00730-2","article-title":"Primary aldosteronism \u2014 a multidimensional syndrome","volume":"18","author":"Turcu","year":"2022","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"2026071419575246200_dgag089-B2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S2213-8587(17)30319-4","article-title":"Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis","volume":"6","author":"Monticone","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"1","key":"2026071419575246200_dgag089-B3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/HJH.0000000000002216","article-title":"Renal damage in primary aldosteronism: a systematic review and meta-analysis","volume":"38","author":"Monticone","year":"2020","journal-title":"J Hypertens"},{"issue":"26","key":"2026071419575246200_dgag089-B4","doi-asserted-by":"crossref","first-page":"e15985","DOI":"10.1097\/MD.0000000000015985","article-title":"Cardiovascular risk in primary aldosteronism: a systematic review and meta-analysis","volume":"98","author":"Wu","year":"2019","journal-title":"Medicine (Baltimore)"},{"key":"2026071419575246200_dgag089-B5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3389\/fendo.2020.00121","article-title":"Long-term mortality for patients of primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis","volume":"11","author":"Meng","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"12","key":"2026071419575246200_dgag089-B6","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/S2213-8587(21)00210-2","article-title":"Diagnosis and treatment of primary aldosteronism","volume":"9","author":"Reincke","year":"2021","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"1","key":"2026071419575246200_dgag089-B7","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1210\/clinem\/dgaa484","article-title":"International histopathology consensus for unilateral primary aldosteronism","volume":"106","author":"Williams","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"2026071419575246200_dgag089-B8","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/s41440-023-01554-x","article-title":"Clinical and biochemical outcomes after adrenalectomy for primary aldosteronism in tertiary and quaternary referral centers: data from SOPRANO study","volume":"47","author":"Marzano","year":"2024","journal-title":"Hypertens Res"},{"issue":"7","key":"2026071419575246200_dgag089-B9","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1097\/HJH.0000000000002070","article-title":"Clinical and biochemical outcomes after adrenalectomy and medical treatment in patients with unilateral primary aldosteronism","volume":"37","author":"Katabami","year":"2019","journal-title":"J Hypertens"},{"issue":"9","key":"2026071419575246200_dgag089-B10","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1093\/ajh\/hpaf029","article-title":"Comparative outcomes of adrenalectomy, mineralocorticoid receptor antagonist, and percutaneous adrenal ablation for primary aldosteronism: a systematic review and network meta-analysis","volume":"38","author":"Yuan","year":"2025","journal-title":"Am J Hypertens"},{"issue":"4","key":"2026071419575246200_dgag089-B11","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1161\/HYPERTENSIONAHA.119.13463","article-title":"Clinical outcomes of 1625 patients with primary aldosteronism subtyped with adrenal vein sampling","volume":"74","author":"Rossi","year":"2019","journal-title":"Hypertension"},{"key":"2026071419575246200_dgag089-B12","doi-asserted-by":"crossref","first-page":"e136\u2013","DOI":"10.5114\/pjr.2019.84178","article-title":"Success rate of adrenal venous sampling and predictors for success: a retrospective study","volume":"84","author":"Chayovan","year":"2019","journal-title":"Pol J Radiol"},{"key":"2026071419575246200_dgag089-B13","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.avsg.2023.08.021","article-title":"Success rate of adrenal venous sampling and its determining factors: experience of a single center in Malaysia","volume":"98","author":"Muhamad Pauzi","year":"2024","journal-title":"Ann Vasc Surg"},{"issue":"4","key":"2026071419575246200_dgag089-B14","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1530\/EJE-14-1161","article-title":"Is there a role for segmental adrenal venous sampling and adrenal sparing surgery in patients with primary aldosteronism?","volume":"173","author":"Satoh","year":"2015","journal-title":"Eur J Endocrinol"},{"issue":"3","key":"2026071419575246200_dgag089-B15","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1161\/HYPERTENSIONAHA.119.14341","article-title":"Precise mapping of intra-adrenal aldosterone activities provides a novel surgical strategy for primary aldosteronism","volume":"76","author":"Kitamoto","year":"2020","journal-title":"Hypertension"},{"issue":"3","key":"2026071419575246200_dgag089-B16","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1161\/HYPERTENSIONAHA.116.08375","article-title":"Anatomical variations of the right adrenal vein: concordance between multidetector computed tomography and catheter venography","volume":"69","author":"Omura","year":"2017","journal-title":"Hypertension"},{"issue":"2","key":"2026071419575246200_dgag089-B17","doi-asserted-by":"crossref","first-page":"411","DOI":"10.2214\/AJR.20.23106","article-title":"Anatomy of left Inferior phrenic vein in patients without portal hypertension","volume":"217","author":"Araki","year":"2021","journal-title":"AJR Am J Roentgenol"},{"issue":"6","key":"2026071419575246200_dgag089-B18","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1210\/clinem\/dgz017","article-title":"Subtyping of primary aldosteronism in the AVIS-2 study: assessment of selectivity and lateralization","volume":"105","author":"Rossitto","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2026071419575246200_dgag089-B19","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1210\/jc.2016-1011","article-title":"Impact of new quick gold nanoparticle-based cortisol assay during adrenal vein sampling for primary aldosteronism","volume":"101","author":"Yoneda","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"2026071419575246200_dgag089-B20","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ejrad.2017.11.017","article-title":"Image quality and radiation dose of low-tube-voltage CT with reduced contrast media for right adrenal vein imaging","volume":"98","author":"Takahashi","year":"2018","journal-title":"Eur J Radiol"},{"issue":"4","key":"2026071419575246200_dgag089-B21","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1507\/endocrj.EJ21-0508","article-title":"Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021","volume":"69","author":"Naruse","year":"2022","journal-title":"Endocr J"},{"issue":"5","key":"2026071419575246200_dgag089-B22","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2026071419575246200_dgag089-B23","doi-asserted-by":"crossref","first-page":"bvae080","DOI":"10.1210\/jendso\/bvae080","article-title":"Screening cutoff values for the detection of aldosterone-producing adenoma by LC-MS\/MS and a novel noncompetitive CLEIA","volume":"8","author":"Ono","year":"2024","journal-title":"J Endocr Soc"},{"issue":"5","key":"2026071419575246200_dgag089-B24","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1038\/s41440-024-01594-x","article-title":"Investigating the cut-off values of captopril challenge test for primary aldosteronism using the novel chemiluminescent enzyme immunoassay method: a retrospective cohort study","volume":"47","author":"Tezuka","year":"2024","journal-title":"Hypertens Res"},{"issue":"1","key":"2026071419575246200_dgag089-B25","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0889-8529(05)70115-8","article-title":"Subclinical Cushing\u2019s syndrome","volume":"29","author":"Reincke","year":"2000","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"1","key":"2026071419575246200_dgag089-B26","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1148\/radiol.2015142159","article-title":"Intra-adrenal aldosterone secretion: segmental adrenal venous sampling for localization","volume":"278","author":"Satani","year":"2016","journal-title":"Radiology"},{"issue":"127","key":"2026071419575246200_dgag089-B27","first-page":"55716","article-title":"A novel method: super-selective adrenal venous sampling","author":"Makita","year":"2017","journal-title":"J Vis Exp"},{"issue":"8","key":"2026071419575246200_dgag089-B28","doi-asserted-by":"crossref","first-page":"e652","DOI":"10.1016\/j.crad.2022.05.010","article-title":"Usefulness and accuracy of segmental adrenal venous sampling on localisation and functional diagnosis of various adrenal lesions in primary aldosteronism","volume":"77","author":"Tannai","year":"2022","journal-title":"Clin Radiol"},{"key":"2026071419575246200_dgag089-B29","doi-asserted-by":"crossref","unstructured":"Omata K, Tezuka Y, Tannai H, et al \u00a0Partial pressure of oxygen-guided adrenal venous sampling in primary aldosteronism. zenodo.org. doi:10.5281\/zenodo.17510581. Date of deposit 3 November 2025.","DOI":"10.1101\/2025.06.29.25330380"},{"issue":"23","key":"2026071419575246200_dgag089-B30","doi-asserted-by":"crossref","first-page":"12971","DOI":"10.1073\/pnas.96.23.12971","article-title":"How oxygen is activated and reduced in respiration","volume":"96","author":"Babcock","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1-2","key":"2026071419575246200_dgag089-B31","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mce.2013.04.014","article-title":"Steroid hormone synthesis in mitochondria","volume":"379","author":"Miller","year":"2013","journal-title":"Mol Cell Endocrinol"},{"issue":"2","key":"2026071419575246200_dgag089-B32","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S0021-9258(18)70928-9","article-title":"Studies in vitamin E deficiency. I. The oxygen consumption of various tissues from the rabbit","volume":"214","author":"Rosenkrantz","year":"1955","journal-title":"J Biol Chem"},{"issue":"4","key":"2026071419575246200_dgag089-B33","first-page":"329","article-title":"Vascularity in human adrenal cortex","volume":"11","author":"Sasano","year":"1998","journal-title":"Mod Pathol"},{"key":"2026071419575246200_dgag089-B34","doi-asserted-by":"crossref","first-page":"995228","DOI":"10.3389\/fendo.2022.995228","article-title":"Vascular and hormonal interactions in the adrenal gland","volume":"13","author":"Abdellatif","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"2026071419575246200_dgag089-B35","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1213\/00000539-198305000-00008","article-title":"Systemic distribution of blood flow in swine while awake and during 1.0 and 1.5 MAC isoflurane anesthesia with or without 50% nitrous oxide","volume":"62","author":"Lundeen","year":"1983","journal-title":"Anesth Analg"},{"issue":"2","key":"2026071419575246200_dgag089-B36","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1476-5381.1977.tb07738.x","article-title":"Tissue blood flow and distribution of cardiac output in cats: changes caused by intravenous infusions of histamine and histamine receptor agonists","volume":"60","author":"Johnston","year":"1977","journal-title":"Br J Pharmacol"},{"issue":"8","key":"2026071419575246200_dgag089-B37","doi-asserted-by":"crossref","first-page":"3566","DOI":"10.1210\/en.2007-0560","article-title":"Regulation of adrenal arterial tone by adrenocorticotropin: the plot thickens","volume":"148","author":"Gomez-Sanchez","year":"2007","journal-title":"Endocrinology"},{"issue":"12","key":"2026071419575246200_dgag089-B38","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1507\/endocrj.EJ22-0492","article-title":"Pathology and gene mutations of aldosterone-producing lesions","volume":"70","author":"Nishimoto","year":"2023","journal-title":"Endocr J"},{"issue":"8","key":"2026071419575246200_dgag089-B39","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.3390\/cancers11081121","article-title":"Intricacies of the molecular machinery of catecholamine biosynthesis and secretion by chromaffin cells of the normal adrenal medulla and in pheochromocytoma and paraganglioma","volume":"11","author":"Berends","year":"2019","journal-title":"Cancers (Basel)"},{"issue":"4","key":"2026071419575246200_dgag089-B40","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF02739775","article-title":"Superoxide dismutase in human adrenal and its disorders: a correlation with development and neoplastic changes","volume":"10","author":"Sasano","year":"1999","journal-title":"Endocr Pathol"},{"issue":"3057","key":"2026071419575246200_dgag089-B41","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1126\/science.118.3057.133","article-title":"Oxygen consumption of adrenal slices from normal and scorbutic guinea pigs and the influence of added ACTH","volume":"118","author":"McKee","year":"1953","journal-title":"Science"},{"issue":"5","key":"2026071419575246200_dgag089-B42","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1210\/endo-53-5-541","article-title":"Effect of hypophysectomy, DDD treatment, and surgical trauma on the oxygen consumption of the various zones of the adrenal cortex","volume":"53","author":"Nichols","year":"1953","journal-title":"Endocrinology"},{"issue":"5 Pt 1","key":"2026071419575246200_dgag089-B43","doi-asserted-by":"crossref","first-page":"E640","DOI":"10.1152\/ajpendo.1989.256.5.E640","article-title":"Low oxygen selectively inhibits aldosterone secretion from bovine adrenocortical cells in vitro","volume":"256","author":"Raff","year":"1989","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"1","key":"2026071419575246200_dgag089-B44","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1210\/endo.132.1.8380376","article-title":"Oxygen availability as a regulatory factor of androgen synthesis by adrenocortical cells","volume":"132","author":"Chabre","year":"1993","journal-title":"Endocrinology"},{"issue":"2","key":"2026071419575246200_dgag089-B45","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/S0021-9258(17)43584-8","article-title":"Oxygen dependence of adrenal cortex cholesterol side chain cleavage. Implications in the rate-limiting steps in steroidogenesis","volume":"259","author":"Stevens","year":"1984","journal-title":"J Biol Chem"},{"issue":"1","key":"2026071419575246200_dgag089-B46","doi-asserted-by":"crossref","first-page":"E199","DOI":"10.1152\/ajpendo.00337.2005","article-title":"Steroidogenesis in human aldosterone-secreting adenomas and adrenal hyperplasias: effects of hypoxia in vitro","volume":"290","author":"Raff","year":"2006","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"10","key":"2026071419575246200_dgag089-B47","doi-asserted-by":"crossref","first-page":"e3969","DOI":"10.1210\/clinem\/dgab420","article-title":"ACTH stimulation maximizes the accuracy of peripheral steroid profiling in primary aldosteronism subtyping","volume":"106","author":"Tezuka","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"issue":"7-8","key":"2026071419575246200_dgag089-B48","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1111\/jocn.13189","article-title":"Evaluation of oxygen saturation values in different body positions in healthy individuals","volume":"25","author":"Ceylan","year":"2016","journal-title":"J Clin Nurs"},{"key":"2026071419575246200_dgag089-B49","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jpeds.2018.04.026","article-title":"Prediction of maximal oxygen uptake by six-Minute walk test and body mass Index in healthy boys","volume":"200","author":"Jalili","year":"2018","journal-title":"J Pediatr"},{"issue":"2","key":"2026071419575246200_dgag089-B50","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/00000542-200402000-00015","article-title":"Obesity decreases perioperative tissue oxygenation","volume":"100","author":"Kabon","year":"2004","journal-title":"Anesthesiology"},{"issue":"4","key":"2026071419575246200_dgag089-B51","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1089\/ham.2021.0039","article-title":"A breathtaking lift: sex and body mass Index differences in cardiopulmonary response in a large cohort of unselected subjects with acute exposure to high altitude","volume":"22","author":"Vignati","year":"2021","journal-title":"High Alt Med Biol"},{"key":"2026071419575246200_dgag089-B52","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.rmed.2017.01.004","article-title":"The effects of obesity on lung volumes and oxygenation","volume":"124","author":"Littleton","year":"2017","journal-title":"Respir Med"},{"issue":"20","key":"2026071419575246200_dgag089-B53","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1056\/NEJM196711162772002","article-title":"Diagnosis and localization of aldosterone-producing adenomas by adrenal-vein catheterization","volume":"277","author":"Melby","year":"1967","journal-title":"N Engl J Med"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcem\/advance-article-pdf\/doi\/10.1210\/clinem\/dgag089\/67257785\/dgag089.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/111\/8\/2293\/67257785\/dgag089.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcem\/article-pdf\/111\/8\/2293\/67257785\/dgag089.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T23:58:20Z","timestamp":1784073500000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/111\/8\/2293\/8509180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,6]]},"references-count":53,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,3,6]]},"published-print":{"date-parts":[[2026,7,15]]}},"URL":"https:\/\/doi.org\/10.1210\/clinem\/dgag089","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,8]]},"published":{"date-parts":[[2026,3,6]]}}}