{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:28:46Z","timestamp":1786580926248,"version":"build-2736575974"},"reference-count":25,"publisher":"The Endocrine Society","issue":"9","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gender-affirming hormone therapy (GAHT) alters hair distribution, a key aspect of gender transition. Transgender women often seek hair reduction, while transgender men typically desire increased hair growth. Previous studies relied on subjective hair assessments, with limited understanding of psychosocial effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate changes in terminal hair growth in transgender men and women (both lasered and non-lasered) using digital microscopy, and their relation to body image during the first 12 months of GAHT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this longitudinal study, 36 participants (20 transgender men, 16 transgender women) initiating GAHT were assessed at baseline, and after 3 and 12 months of GAHT. Hair densities were measured using digital microscopy. Psychosocial outcomes were evaluated using the Body Appreciation Scale-2 and satisfaction questionnaires.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After 12 months, transgender women showed significant reductions in hair density on the upper lip (\u221217 hairs\/cm2, CI \u221232, \u22122), chin (\u221228 hairs\/cm2, CI \u221247, \u22128), and upper abdomen (\u22126 hairs\/cm2, CI \u221212,0), with no significant differences between lasered and non-lasered women. Transgender men exhibited significant increases on the upper lip (+21 hairs\/cm2, CI 11-30), chin (+13 hairs\/cm2, CI 3-24), upper (+17 hairs\/cm2, CI 8-23) and lower abdomen (+20 hairs\/cm2, CI 11-28), and thighs (+14 hairs\/cm2, CI 7-21). Both groups reported improved body appreciation, satisfaction with hair growth, and gender congruence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>GAHT induces measurable, location-specific changes in terminal hair growth in transgender women and men, accompanied by improvements in body image and satisfaction. Digital microscopy provides a valuable tool for future studies comparing GAHT regimens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgag139","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T11:57:13Z","timestamp":1775649433000},"page":"2426-2435","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative effects of sex hormones on hair growth and patient satisfaction"],"prefix":"10.1210","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4912-7814","authenticated-orcid":false,"given":"Romy W P M","family":"de Kroon","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Endocrine Laboratory , Meibergdreef 9, 1105 AZ, Amsterdam ,","place":["The Netherlands"]},{"name":"Amsterdam Gastroenterology, Endocrinology & Metabolism , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Strating","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Endocrine Laboratory , Meibergdreef 9, 1105 AZ, Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6712-9955","authenticated-orcid":false,"given":"Annemieke C","family":"Heijboer","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Endocrine Laboratory , Meibergdreef 9, 1105 AZ, Amsterdam ,","place":["The Netherlands"]},{"name":"Amsterdam Gastroenterology, Endocrinology & Metabolism , Amsterdam ,","place":["The Netherlands"]},{"name":"Department of Laboratory Medicine, Amsterdam University Medical Center, Location Vrije Universiteit, Endocrine Laboratory , De Boelelaan 1117, 1081 HV, Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3620-5617","authenticated-orcid":false,"given":"Martin","family":"den Heijer","sequence":"additional","affiliation":[{"name":"Amsterdam Gastroenterology, Endocrinology & Metabolism , Amsterdam ,","place":["The Netherlands"]},{"name":"Department of Internal Medicine, Division of Endocrinology, Amsterdam University Medical Center, Location Vrije Universiteit , De Boelelaan 1117, 1081 HV, Amsterdam ,","place":["The Netherlands"]},{"name":"Center of Expertise on Gender Dysphoria, Amsterdam University Medical Center , De Boelelaan 1117, 1081 HV, Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"issue":"1","key":"2026081219570001800_dgag139-B1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s12119-025-10429-x","article-title":"Uncovering the hairlessness norm: a review on women's body hair from a social-psychological perspective","volume":"30","author":"\u015eahin","year":"2026","journal-title":"Sex Cult"},{"issue":"4","key":"2026081219570001800_dgag139-B2","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1471-6402.2004.00155.x","article-title":"Attitudes toward women's body hair: relationship with disgust sensitivity","volume":"28","author":"Tiggemann","year":"2004","journal-title":"Psychol Women Quart"},{"issue":"1","key":"2026081219570001800_dgag139-B3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.54097\/c2a51059","article-title":"Aesthetic exploration and identity perception of body hair","volume":"7","author":"Wang","year":"2024","journal-title":"Highlights in Art and Design"},{"issue":"3","key":"2026081219570001800_dgag139-B4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.5694\/mja2.50259","article-title":"Position statement on the hormonal management of adult transgender and gender diverse individuals","volume":"211","author":"Cheung","year":"2019","journal-title":"Med J Aust"},{"issue":"1","key":"2026081219570001800_dgag139-B5","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1080\/19317611.2016.1227013","article-title":"Transitioning transgender: investigating the important aspects of the transition: a brief report","volume":"29","author":"Fein","year":"2017","journal-title":"Int J Sex Health"},{"issue":"3","key":"2026081219570001800_dgag139-B6","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s10508-015-0614-1","article-title":"Body satisfaction and physical appearance in gender dysphoria","volume":"45","author":"van de Grift","year":"2016","journal-title":"Arch Sex Behav. 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