{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:11:16Z","timestamp":1788876676410,"version":"build-2803163510"},"reference-count":57,"publisher":"The Endocrine Society","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>With advancing technologies and expanding indications for existing therapies, ethical dilemmas increasingly arise in pediatric endocrinology practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This article presents practical, case-based scenarios to guide clinicians in navigating common ethical challenges in pediatric endocrinology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Cases<\/jats:title>\n                    <jats:p>We present 4 case vignettes which present ethical dilemmas regarding (1) growth hormone treatment prescribed for idiopathic short stature; (2) precocious puberty management in a child with neurodevelopmental delay; (3) technology use in type 1 diabetes care; and (4) glucagon-like peptide 1 receptor agonist use for obesity management. For each case, we outline patient presentations and management approaches which highlight the application of the four-principle ethical framework based on Beauchamp and Childress. Salient historical events are mentioned to serve as a basis to contextualize and situate the specific ethical dilemmas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ethical dilemmas have the potential to arise in the everyday practice of pediatric endocrinology. Application of the principles of beneficence, non-maleficence, respect for autonomy, and justice will allow for a pragmatic incorporation of ethical decision making in medical care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/clinem\/dgag354","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T11:42:13Z","timestamp":1787830933000},"source":"Crossref","is-referenced-by-count":0,"title":["Approach to the patient: ethics cases in pediatric endocrinology and their management"],"prefix":"10.1210","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1949-4367","authenticated-orcid":false,"given":"Jennifer M","family":"Ladd","sequence":"first","affiliation":[{"name":"Section of Endocrinology, Department of Pediatrics, Nationwide Children's Hospital\/the Ohio State University College of Medicine , Columbus, OH 43205 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2310-0111","authenticated-orcid":false,"given":"Meaghann S","family":"Weaver","sequence":"additional","affiliation":[{"name":"Bioethics Program and Division of Palliative Care, Department of Oncology, St Jude Children's Research Hospital , Memphis, TN 38105 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4514-2702","authenticated-orcid":false,"given":"Rohan K","family":"Henry","sequence":"additional","affiliation":[{"name":"Section of Endocrinology, Department of Pediatrics, Nationwide Children's Hospital\/the Ohio State University College of Medicine , Columbus, OH 43205 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"2026090809534492000_dgag354-B1","volume-title":"Resolving Ethical Dilemmas A Guide for Clinicians","author":"Lo","year":"2020","edition":"6th ed"},{"issue":"1","key":"2026090809534492000_dgag354-B2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.yapd.2024.12.002","article-title":"Ethical issues in pediatric endocrinology: a primer for the practitioner","volume":"72","author":"Ladd","year":"2025","journal-title":"Adv Pediatr"},{"key":"2026090809534492000_dgag354-B3","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/978-3-030-00719-5","volume-title":"Medical Ethics in Clinical Practice","author":"Zwitter","year":"2019"},{"issue":"Suppl 1","key":"2026090809534492000_dgag354-B4","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1542\/peds.2013-3608D","article-title":"Relational autonomy: moving beyond the limits of isolated individualism","volume":"133","author":"Walter","year":"2014","journal-title":"Pediatrics. 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