{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T14:12:23Z","timestamp":1724508743660},"reference-count":68,"publisher":"The Endocrine Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10,1]]},"DOI":"10.1210\/en.2013-1334","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T03:17:13Z","timestamp":1373339833000},"page":"3764-3775","source":"Crossref","is-referenced-by-count":9,"title":["Growth Hormone Secretagogues Exert Differential Effects on Skeletal Muscle Calcium Homeostasis in Male Rats Depending on the Peptidyl\/Nonpeptidyl Structure"],"prefix":"10.1210","volume":"154","author":[{"given":"Antonella","family":"Liantonio","sequence":"first","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Gramegna","sequence":"additional","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Carbonara","sequence":"additional","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeriana Teresa","family":"Sblendorio","sequence":"additional","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabata","family":"Pierno","sequence":"additional","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bodva\u00ebl","family":"Fraysse","sequence":"additional","affiliation":[{"name":"Physiopathologie Animale et bioTh\u00e9rapie du muscle et du syst\u00e8me nerveux (B.F.), Ecole Nationale V\u00e9t\u00e9rinaire, Agroalimentaire et de l'Alimentation, Nantes-Atlantique, 44307 Nantes Cedex 03, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Giannuzzi","sequence":"additional","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Rizzi","sequence":"additional","affiliation":[{"name":"Department of Health Sciences (L.R., A.T.), University of Milano-Bicocca, 20900 Monza, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Torsello","sequence":"additional","affiliation":[{"name":"Department of Health Sciences (L.R., A.T.), University of Milano-Bicocca, 20900 Monza, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Conte","family":"Camerino","sequence":"additional","affiliation":[{"name":"Section of Pharmacology (A.L., G.G., G.C., V.T.S., S.P., V.G., D.C.C.), Department of Pharmacy-Drug Sciences, University of Bari, Campus, 70125 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","reference":[{"key":"2019041121240685700_B1","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/45230","article-title":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach","volume":"402","author":"Kojima","year":"1999","journal-title":"Nature"},{"key":"2019041121240685700_B2","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1210\/er.2002-0029","article-title":"Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin","volume":"25","author":"van der Lely","year":"2004","journal-title":"Endocr Rev"},{"key":"2019041121240685700_B3","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.tem.2005.09.004","article-title":"Developments in ghrelin biology and potential clinical relevance","volume":"16","author":"Smith","year":"2005","journal-title":"Trends Endocrinol Metab"},{"key":"2019041121240685700_B4","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/MCO.0b013e328303dee4","article-title":"The role of ghrelin and ghrelin analogues in wasting disease","volume":"11","author":"Kamiji","year":"2008","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"2019041121240685700_B5","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s13539-010-0011-5","article-title":"Ghrelin for cachexia","volume":"1","author":"Akamizu","year":"2010","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2019041121240685700_B6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1749-6632.2010.05509.x","article-title":"Translational research of ghrelin","volume":"1200","author":"Ueno","year":"2010","journal-title":"Ann NY Acad Sci"},{"key":"2019041121240685700_B7","doi-asserted-by":"crossref","first-page":"3722","DOI":"10.1210\/en.2007-1650","article-title":"Efficacy of ghrelin as a therapeutic approach for age-related physiological changes","volume":"149","author":"Ariyasu","year":"2008","journal-title":"Endocrinology"},{"key":"2019041121240685700_B8","doi-asserted-by":"crossref","first-page":"601","DOI":"10.7326\/0003-4819-149-9-200811040-00003","article-title":"Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial","volume":"149","author":"Nass","year":"2008","journal-title":"Ann Intern Med"},{"key":"2019041121240685700_B9","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1210\/jc.2008-0632","article-title":"Effects of an oral growth hormone secretagogue in older adults","volume":"94","author":"White","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"2019041121240685700_B10","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.bbrc.2011.07.086","article-title":"Therapeutic potential of ghrelin treatment for unloading-induced muscle atrophy in mice","volume":"412","author":"Koshinaka","year":"2011","journal-title":"Biochem Biophys Res Commun"},{"key":"2019041121240685700_B11","doi-asserted-by":"crossref","first-page":"RC26","DOI":"10.1007\/BF03345096","article-title":"EP1572: a novel peptido-mimetic GH secretagogue with potent and selective GH-releasing activity in man","volume":"25","author":"Broglio","year":"2002","journal-title":"J Endocrinol Invest"},{"key":"2019041121240685700_B12","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1210\/er.2004-0019","article-title":"Development of growth hormone secretagogues","volume":"26","author":"Smith","year":"2005","journal-title":"Endocr Rev"},{"key":"2019041121240685700_B13","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/cmdc.200700015","article-title":"Recent developments in ghrelin receptor ligands","volume":"2","author":"Moulin","year":"2007","journal-title":"ChemMedChem"},{"key":"2019041121240685700_B14","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2174\/157016309787581048","article-title":"Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect","volume":"6","author":"Cordido","year":"2009","journal-title":"Curr Drug Discov Technol"},{"key":"2019041121240685700_B15","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1359\/jbmr.1998.13.7.1158","article-title":"Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males","volume":"13","author":"Svensson","year":"1998","journal-title":"J Bone Miner Res"},{"key":"2019041121240685700_B16","doi-asserted-by":"crossref","first-page":"677","DOI":"10.7326\/0003-4819-149-9-200811040-00010","article-title":"Use of growth hormone secretagogues to prevent or treat the effects of aging: not yet ready for prime time","volume":"149","author":"Blackman","year":"2008","journal-title":"Ann Intern Med"},{"key":"2019041121240685700_B17","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1161\/01.CIR.0000149746.62908.BB","article-title":"Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure","volume":"110","author":"Nagaya","year":"2004","journal-title":"Circulation"},{"key":"2019041121240685700_B18","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.tem.2005.11.004","article-title":"Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system","volume":"17","author":"Cao","year":"2006","journal-title":"Trends Endocrinol Metab"},{"key":"2019041121240685700_B19","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.1210\/endo.140.9.6948","article-title":"Growth hormone-independent cardioprotective effects of hexarelin in the rat","volume":"140","author":"Locatelli","year":"1999","journal-title":"Endocrinology"},{"key":"2019041121240685700_B20","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1055\/s-2004-835367","article-title":"Ghrelin and synthetic growth hormone secretagogues are cardioactive molecules with identities and differences","volume":"4","author":"Benso","year":"2004","journal-title":"Semin Vasc Med"},{"key":"2019041121240685700_B21","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.1210\/en.2003-0025","article-title":"The positive inotropic and calcium-mobilizing effects of growth hormone-releasing peptides on rat heart","volume":"144","author":"Xu","year":"2003","journal-title":"Endocrinology"},{"key":"2019041121240685700_B22","doi-asserted-by":"crossref","first-page":"4446","DOI":"10.1210\/en.2009-1432","article-title":"Effects of GH secretagogues on contractility and Ca2+ homeostasis of isolated adult rat ventricular myocytes","volume":"151","author":"Sun","year":"2010","journal-title":"Endocrinology"},{"key":"2019041121240685700_B23","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1210\/en.2009-0877","article-title":"Growth hormone secretagogues reduce transient outward K+ current via phospholipase C\/protein kinase C signaling pathway in rat ventricular myocytes","volume":"151","author":"Sun","year":"2010","journal-title":"Endocrinology"},{"key":"2019041121240685700_B24","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1083\/jcb.200207165","article-title":"Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1\/2 and PI 3-kinase\/AKT","volume":"159","author":"Baldanzi","year":"2002","journal-title":"J Cell Biol"},{"key":"2019041121240685700_B25","doi-asserted-by":"crossref","first-page":"H1063","DOI":"10.1152\/ajpheart.00648.2003","article-title":"Hexarelin protects rat cardiomyocytes from angiotensin II-induced apoptosis in vitro","volume":"286","author":"Pang","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019041121240685700_B26","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.mce.2011.02.012","article-title":"Ghrelin and cachexia: will treatment with GHSR-1a agonists make a difference for patients suffering from chronic wasting syndromes?","volume":"340","author":"DeBoer","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"2019041121240685700_B27","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/sj.bjp.0705284","article-title":"Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor","volume":"139","author":"Pierno","year":"2003","journal-title":"Br J Pharmacol"},{"key":"2019041121240685700_B28","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1085\/jgp.200409173","article-title":"Increased excitability of acidified skeletal muscle: role of chloride conductance","volume":"125","author":"Pedersen","year":"2005","journal-title":"J Gen Physiol"},{"key":"2019041121240685700_B29","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s11910-011-0238-3","article-title":"Novel insights into the pathomechanisms of skeletal muscle channelopathies","volume":"12","author":"Burge","year":"2012","journal-title":"Curr Neurol Neurosci Rep"},{"key":"2019041121240685700_B30","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1021\/jm070024h","article-title":"Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1","volume":"50","author":"Demange","year":"2007","journal-title":"J Med Chem"},{"key":"2019041121240685700_B31","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.1021\/jm0704550","article-title":"Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations","volume":"50","author":"Moulin","year":"2007","journal-title":"J Med Chem"},{"key":"2019041121240685700_B32","first-page":"e67","article-title":"Ghrelin control of GH secretion and feeding behaviour: the role of the GHS-R1a receptor studied in vivo and in vitro using novel non-peptide ligands","volume":"13","author":"Bresciani","year":"2008","journal-title":"Eat Weight Disord"},{"key":"2019041121240685700_B33","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1096\/fj.02-1012fje","article-title":"Decrease in resting calcium and calcium entry associated with slow-to-fast transition in unloaded rat soleus muscle","volume":"17","author":"Fraysse","year":"2003","journal-title":"FASEB J"},{"key":"2019041121240685700_B34","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1124\/jpet.106.118331","article-title":"Fluvastatin and atorvastatin affect calcium homeostasis of rat skeletal muscle fibers in vivo and in vitro by impairing the sarcoplasmic reticulum\/mitochondria Ca2+-release system","volume":"321","author":"Liantonio","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"2019041121240685700_B35","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","article-title":"A new generation of Ca2+ indicators with greatly improved fluorescence properties","volume":"260","author":"Grynkiewicz","year":"1985","journal-title":"J Biol Chem"},{"key":"2019041121240685700_B36","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1152\/physrev.1997.77.4.901","article-title":"Store depletion and calcium influx","volume":"77","author":"Parekh","year":"1997","journal-title":"Physiol Rev"},{"key":"2019041121240685700_B37","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1091\/mbc.e06-05-0402","article-title":"Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells","volume":"18","author":"Filigheddu","year":"2007","journal-title":"Mol Biol Cell"},{"key":"2019041121240685700_B38","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.lfs.2007.11.019","article-title":"GHRP-2, a GHS-R agonist, directly acts on myocytes to attenuate the dexamethasone-induced expressions of muscle-specific ubiquitin ligases, Atrogin-1 and MuRF1","volume":"82","author":"Yamamoto","year":"2008","journal-title":"Life Sci"},{"key":"2019041121240685700_B39","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1387-2656(05)11004-7","article-title":"Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction","volume":"11","author":"Berridge","year":"2005","journal-title":"Biotechnol Annu Rev"},{"key":"2019041121240685700_B40","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2131\/jts.32.57","article-title":"Simvastatin reduces insulin-like growth factor-1 signaling in differentiating C2C12 mouse myoblast cells in an HMG-CoA reductase inhibition-independent manner","volume":"32","author":"Ogura","year":"2007","journal-title":"J Toxicol Sci"},{"key":"2019041121240685700_B41","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1039\/B517914A","article-title":"Advances in methods and algorithms in a modern quantum chemistry program package","volume":"8","author":"Shao","year":"2006","journal-title":"Phys Chem Chem Phys"},{"key":"2019041121240685700_B42","volume-title":"Guide to Molecular Mechanics and Quantum Chemical Calculations","author":"Hehre","year":"2006","edition":"2nd ed"},{"key":"2019041121240685700_B43","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1021\/mp0700209","article-title":"The Rule of Five revisited: applying log D in place of log P in drug-likeness filters","volume":"4","author":"Bhal","year":"2007","journal-title":"Mol Pharm"},{"key":"2019041121240685700_B44","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1210\/endo.143.2.8654","article-title":"The antiproliferative effect of synthetic peptidyl GH secretagogues in human CALU-1 lung carcinoma cells","volume":"143","author":"Gh\u00e8","year":"2002","journal-title":"Endocrinology"},{"key":"2019041121240685700_B45","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1530\/eje.0.1500173","article-title":"Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines","volume":"150","author":"Cassoni","year":"2004","journal-title":"Eur J Endocrinol"},{"key":"2019041121240685700_B46","doi-asserted-by":"crossref","first-page":"R7","DOI":"10.1677\/joe.0.172R007","article-title":"Expression and action of the growth hormone releasing peptide ghrelin and its receptor in prostate cancer cell lines","volume":"172","author":"Jeffery","year":"2002","journal-title":"J Endocrinol"},{"key":"2019041121240685700_B47","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1046\/j.1365-2826.2002.00810.x","article-title":"Ghrelin acts on leptin-responsive neurones in the rat arcuate nucleus","volume":"14","author":"Traebert","year":"2002","journal-title":"J Neuroendocrinol"},{"key":"2019041121240685700_B48","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1042\/bss0660167","article-title":"The mitochondrial permeability transition pore","volume":"66","author":"Crompton","year":"1999","journal-title":"Biochem Soc Symp"},{"key":"2019041121240685700_B49","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s10541-005-0100-9","article-title":"A historical review of cellular calcium handling, with emphasis on mitochondria","volume":"70","author":"Saris","year":"2005","journal-title":"Biochemistry (Mosc)"},{"key":"2019041121240685700_B50","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00726-012-1355-2","article-title":"The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist","volume":"44","author":"Moulin","year":"2013","journal-title":"Amino Acids"},{"key":"2019041121240685700_B51","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.bbabio.2008.05.449","article-title":"The versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death","volume":"1777","author":"Rimessi","year":"2008","journal-title":"Biochim Biophys Acta"},{"key":"2019041121240685700_B52","first-page":"3803","article-title":"Growth hormone secretagogue binding sites in peripheral human tissues","volume":"85","author":"Papotti","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"2019041121240685700_B53","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1210\/jcem.87.6.8739","article-title":"The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans","volume":"87","author":"Gnanapavan","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"2019041121240685700_B54","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000105141","article-title":"Heterogeneity of ghrelin\/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin\/GHS receptors","volume":"86","author":"Muccioli","year":"2007","journal-title":"Neuroendocrinology"},{"key":"2019041121240685700_B55","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1097\/MCO.0b013e3281e38942","article-title":"The energetics of wasting diseases","volume":"10","author":"Kulstad","year":"2007","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"2019041121240685700_B56","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.surg.2004.03.014","article-title":"Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism","volume":"136","author":"Menconi","year":"2004","journal-title":"Surgery"},{"key":"2019041121240685700_B57","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1016\/j.biocel.2005.03.010","article-title":"Ca(2+)-dependent proteolysis in muscle wasting","volume":"37","author":"Costelli","year":"2005","journal-title":"Int J Biochem Cell Biol"},{"key":"2019041121240685700_B58","doi-asserted-by":"crossref","first-page":"R1589","DOI":"10.1152\/ajpregu.00668.2005","article-title":"Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1\/MAFbx and MuRF1 expression","volume":"290","author":"Fareed","year":"2006","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"2019041121240685700_B59","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm1155","article-title":"Calcium signalling: dynamics, homeostasis and remodelling","volume":"4","author":"Berridge","year":"2003","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2019041121240685700_B60","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.nbd.2005.07.012","article-title":"Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone","volume":"21","author":"Fraysse","year":"2006","journal-title":"Neurobiol Dis"},{"key":"2019041121240685700_B61","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00000658-200101000-00003","article-title":"Muscle cachexia: current concepts of intracellular mechanisms and molecular regulation","volume":"233","author":"Hasselgren","year":"2001","journal-title":"Ann Surg"},{"key":"2019041121240685700_B62","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1196\/annals.1363.013","article-title":"The role of Ca2+ in muscle cell damage","volume":"1066","author":"Gissel","year":"2005","journal-title":"Ann NY Acad Sci"},{"key":"2019041121240685700_B63","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1532-5415.2004.52156.x","article-title":"The effects of MK-0677, an oral growth hormone secretagogue, in patients with hip fracture","volume":"52","author":"Bach","year":"2004","journal-title":"J Am Geriatr Soc"},{"key":"2019041121240685700_B64","doi-asserted-by":"crossref","first-page":"R893","DOI":"10.1152\/ajpregu.00015.2008","article-title":"Ghrelin inhibits skeletal muscle protein breakdown in rats with thermal injury through normalizing elevated expression of E3 ubiquitin ligases MuRF1 and MAFbx","volume":"296","author":"Balasubramaniam","year":"2009","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"2019041121240685700_B65","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1016\/j.peptides.2009.06.029","article-title":"Ghrelin receptor agonist, GHRP-2, attenuates burn injury-induced MuRF-1 and MAFbx expression and muscle proteolysis in rats","volume":"30","author":"Sheriff","year":"2009","journal-title":"Peptides"},{"key":"2019041121240685700_B66","doi-asserted-by":"crossref","first-page":"e35708","DOI":"10.1371\/journal.pone.0035708","article-title":"Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial","volume":"7","author":"Miki","year":"2012","journal-title":"PLoS One"},{"key":"2019041121240685700_B67","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/B978-0-12-381272-8.00025-8","article-title":"Clinical application of ghrelin for chronic respiratory diseases","volume":"514","author":"Matsumoto","year":"2012","journal-title":"Methods Enzymol"},{"key":"2019041121240685700_B68","first-page":"611","article-title":"Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice","volume":"123","author":"Porporato","year":"2013","journal-title":"J Clin Invest"}],"container-title":["Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/endo\/article-pdf\/154\/10\/3764\/13060643\/endo3764.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T20:35:46Z","timestamp":1645994146000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/endo\/article\/154\/10\/3764\/2424024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,1]]},"references-count":68,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/en.2013-1334","relation":{},"ISSN":["0013-7227","1945-7170"],"issn-type":[{"value":"0013-7227","type":"print"},{"value":"1945-7170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,1]]}}}