{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:24:58Z","timestamp":1791123898962,"version":"4.1.0"},"reference-count":23,"publisher":"The Endocrine Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,10,1]]},"DOI":"10.1210\/en.2014-1199","type":"journal-article","created":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T17:27:33Z","timestamp":1406050053000},"page":"3891-3898","source":"Crossref","is-referenced-by-count":29,"title":["Genetic Rescue of Glycosylation-deficient Fgf23 in the Galnt3 Knockout Mouse"],"prefix":"10.1210","volume":"155","author":[{"given":"Shoji","family":"Ichikawa","sequence":"first","affiliation":[{"name":"Departments of Medicine (S.I., A.K.G., L.R.P., N.M.S., M.J.E.), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amie K.","family":"Gray","sequence":"additional","affiliation":[{"name":"Departments of Medicine (S.I., A.K.G., L.R.P., N.M.S., M.J.E.), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah R.","family":"Padgett","sequence":"additional","affiliation":[{"name":"Departments of Medicine (S.I., A.K.G., L.R.P., N.M.S., M.J.E.), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Allen","sequence":"additional","affiliation":[{"name":"Anatomy and Cell Biology (M.R.A.), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica L.","family":"Clinkenbeard","sequence":"additional","affiliation":[{"name":"Medical and Molecular Genetics (E.L.C., K.E.W., M.J.E), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole M.","family":"Sarpa","sequence":"additional","affiliation":[{"name":"Departments of Medicine (S.I., A.K.G., L.R.P., N.M.S., M.J.E.), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth E.","family":"White","sequence":"additional","affiliation":[{"name":"Medical and Molecular Genetics (E.L.C., K.E.W., M.J.E), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Econs","sequence":"additional","affiliation":[{"name":"Departments of Medicine (S.I., A.K.G., L.R.P., N.M.S., M.J.E.), Indiana University School of Medicine, Indianapolis, Indiana 46202"},{"name":"Medical and Molecular Genetics (E.L.C., K.E.W., M.J.E), Indiana University School of Medicine, Indianapolis, Indiana 46202"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"issue":"3","key":"2019041118235036100_B1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1359\/JBMR.0301264","article-title":"FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis","volume":"19","author":"Shimada","year":"2004","journal-title":"J Bone Miner Res"},{"issue":"7","key":"2019041118235036100_B2","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1210\/en.2003-1768","article-title":"Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis","volume":"145","author":"Larsson","year":"2004","journal-title":"Endocrinology"},{"issue":"11","key":"2019041118235036100_B3","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.1210\/en.2004-0233","article-title":"Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders","volume":"145","author":"Bai","year":"2004","journal-title":"Endocrinology"},{"issue":"11","key":"2019041118235036100_B4","doi-asserted-by":"crossref","first-page":"6500","DOI":"10.1073\/pnas.101545198","article-title":"Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia","volume":"98","author":"Shimada","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"2019041118235036100_B5","doi-asserted-by":"crossref","first-page":"F1088","DOI":"10.1152\/ajprenal.00474.2004","article-title":"Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism","volume":"289","author":"Shimada","year":"2005","journal-title":"Am J Physiol Renal Physiol"},{"issue":"3","key":"2019041118235036100_B6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/81664","article-title":"Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23","volume":"26","author":"ADHR Consortium","year":"2000","journal-title":"Nat Genet"},{"issue":"6","key":"2019041118235036100_B7","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1046\/j.1523-1755.2001.00064.x","article-title":"Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23","volume":"60","author":"White","year":"2001","journal-title":"Kidney Int"},{"issue":"4","key":"2019041118235036100_B8","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/ajmg.a.33337","article-title":"Clinical variability of familial tumoral calcinosis caused by novel GALNT3 mutations","volume":"152A","author":"Ichikawa","year":"2010","journal-title":"Am J Med Genet A"},{"issue":"4","key":"2019041118235036100_B9","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1210\/jc.2004-2302","article-title":"A novel GALNT3 mutation in a pseudoautosomal dominant form of tumoral calcinosis: evidence that the disorder is autosomal recessive","volume":"90","author":"Ichikawa","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2019041118235036100_B10","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/ng1358","article-title":"Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis","volume":"36","author":"Topaz","year":"2004","journal-title":"Nat Genet"},{"issue":"27","key":"2019041118235036100_B11","doi-asserted-by":"crossref","first-page":"18370","DOI":"10.1074\/jbc.M602469200","article-title":"Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation","volume":"281","author":"Kato","year":"2006","journal-title":"J Biol Chem"},{"issue":"2","key":"2019041118235036100_B12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1359\/jbmr.061105","article-title":"Hyperostosis-hyperphosphatemia syndrome: a congenital disorder of O-glycosylation associated with augmented processing of fibroblast growth factor 23","volume":"22","author":"Frishberg","year":"2007","journal-title":"J Bone Miner Res"},{"issue":"20","key":"2019041118235036100_B13","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1002\/ajmg.a.31947","article-title":"Two novel GALNT3 mutations in familial tumoral calcinosis","volume":"143","author":"Garringer","year":"2007","journal-title":"Am J Med Genet A"},{"issue":"5","key":"2019041118235036100_B14","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1210\/jc.2006-1825","article-title":"Novel GALNT3 mutations causing hyperostosis-hyperphosphatemia syndrome result in low intact fibroblast growth factor 23 concentrations","volume":"92","author":"Ichikawa","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"2019041118235036100_B15","doi-asserted-by":"crossref","first-page":"4472","DOI":"10.1210\/jc.2006-1247","article-title":"Tumoral calcinosis presenting with eyelid calcifications due to novel missense mutations in the glycosyl transferase domain of the GALNT3 gene","volume":"91","author":"Ichikawa","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2019041118235036100_B16","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1210\/en.2008-0877","article-title":"Ablation of the Galnt3 gene leads to low-circulating intact fibroblast growth factor 23 (Fgf23) concentrations and hyperphosphatemia despite increased Fgf23 expression","volume":"150","author":"Ichikawa","year":"2009","journal-title":"Endocrinology"},{"issue":"46","key":"2019041118235036100_B17","doi-asserted-by":"crossref","first-page":"E1146","DOI":"10.1073\/pnas.1110905108","article-title":"Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice","volume":"108","author":"Farrow","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"2019041118235036100_B18","doi-asserted-by":"crossref","first-page":"4504","DOI":"10.1210\/en.2011-1137","article-title":"Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis","volume":"152","author":"Ichikawa","year":"2011","journal-title":"Endocrinology"},{"issue":"2","key":"2019041118235036100_B19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/jbmr.544","article-title":"A Phex mutation in a murine model of X-linked hypophosphatemia alters phosphate responsiveness of bone cells","volume":"27","author":"Ichikawa","year":"2012","journal-title":"J Bone Miner Res"},{"issue":"8","key":"2019041118235036100_B20","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1210\/endo.143.8.8795","article-title":"Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo","volume":"143","author":"Shimada","year":"2002","journal-title":"Endocrinology"},{"issue":"11","key":"2019041118235036100_B21","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.1210\/jc.2011-1239","article-title":"Iron modifies plasma FGF23 differently in autosomal dominant hypophosphatemic rickets and healthy humans","volume":"96","author":"Imel","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2019041118235036100_B22","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1359\/jbmr.070107","article-title":"FGF23 concentrations vary with disease status in autosomal dominant hypophosphatemic rickets","volume":"22","author":"Imel","year":"2007","journal-title":"J Bone Miner Res"},{"issue":"8","key":"2019041118235036100_B23","doi-asserted-by":"crossref","first-page":"F833","DOI":"10.1152\/ajprenal.00133.2013","article-title":"Renal-specific and inducible depletion of NaPi-IIc\/Slc34a3, the cotransporter mutated in HHRH, does not affect phosphate or calcium homeostasis in mice","volume":"306","author":"Myakala","year":"2014","journal-title":"Am J Physiol Renal Physiol"}],"container-title":["Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/endo\/article-pdf\/155\/10\/3891\/10827009\/endo3891.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T06:31:11Z","timestamp":1555050671000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/endo\/article\/155\/10\/3891\/2423302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,1]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/en.2014-1199","relation":{},"ISSN":["0013-7227","1945-7170"],"issn-type":[{"value":"0013-7227","type":"print"},{"value":"1945-7170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,1]]}}}