{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:32:46Z","timestamp":1790422366791,"version":"4.1.0"},"reference-count":68,"publisher":"The Endocrine Society","issue":"9","funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32GM008336"],"award-info":[{"award-number":["T32GM008336"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32GM083864"],"award-info":[{"award-number":["T32GM083864"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["HD44569"],"award-info":[{"award-number":["HD44569"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"DOI":"10.1210\/en.2018-00533","type":"journal-article","created":{"date-parts":[[2018,8,6]],"date-time":"2018-08-06T14:03:11Z","timestamp":1533564191000},"page":"3403-3420","source":"Crossref","is-referenced-by-count":23,"title":["Germ Cell\u2013Specific Retinoic Acid Receptor \u03b1 Functions in Germ Cell Organization, Meiotic Integrity, and Spermatogonia"],"prefix":"10.1210","volume":"159","author":[{"given":"Natalie R","family":"Peer","sequence":"first","affiliation":[{"name":"School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sze Ming","family":"Law","sequence":"additional","affiliation":[{"name":"School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Murdoch","sequence":"additional","affiliation":[{"name":"School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, Washington"},{"name":"Department of Animal and Veterinary Science, University of Idaho, Moscow, Idaho"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia H","family":"Goulding","sequence":"additional","affiliation":[{"name":"Laboratory of Reproductive and Developmental Biology, Gamete Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward M","family":"Eddy","sequence":"additional","affiliation":[{"name":"Laboratory of Reproductive and Developmental Biology, Gamete Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwanhee","family":"Kim","sequence":"additional","affiliation":[{"name":"School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2018,8,6]]},"reference":[{"key":"2019041121411706000_B1","volume-title":"Histological and Histopathological Evaluation of the Testis","author":"Russell","year":"1990"},{"issue":"6","key":"2019041121411706000_B2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1084\/jem.42.6.753","article-title":"Tissue changes following deprivation of fat-soluble A vitamin","volume":"42","author":"Wolbach","year":"1925","journal-title":"J Exp Med"},{"issue":"4","key":"2019041121411706000_B3","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1095\/biolreprod21.4.891","article-title":"Spermatogenic response to vitamin A in vitamin A deficient rats","volume":"21","author":"Huang","year":"1979","journal-title":"Biol Reprod"},{"issue":"4","key":"2019041121411706000_B4","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1095\/biolreprod42.4.677","article-title":"The origin of the synchronization of the seminiferous epithelium in vitamin A-deficient rats after vitamin A replacement","volume":"42","author":"Van Pelt","year":"1990","journal-title":"Biol Reprod"},{"issue":"3","key":"2019041121411706000_B5","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1095\/biolreprod43.3.363","article-title":"Synchronization of the seminiferous epithelium after vitamin A replacement in vitamin A-deficient mice","volume":"43","author":"van Pelt","year":"1990","journal-title":"Biol Reprod"},{"issue":"2","key":"2019041121411706000_B6","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1095\/biolreprod.110.086157","article-title":"Vitamin A deficiency results in meiotic failure and accumulation of undifferentiated spermatogonia in prepubertal mouse testis","volume":"84","author":"Li","year":"2011","journal-title":"Biol Reprod"},{"issue":"2","key":"2019041121411706000_B7","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1210\/endo-128-2-697","article-title":"Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells","volume":"128","author":"van Pelt","year":"1991","journal-title":"Endocrinology"},{"issue":"5","key":"2019041121411706000_B8","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1095\/biolreprod28.5.1163","article-title":"Failure of spermatid release under various vitamin A states\u2014an indication of delayed spermiation","volume":"28","author":"Huang","year":"1983","journal-title":"Biol Reprod"},{"key":"2019041121411706000_B9","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1749-6632.1989.tb25895.x","article-title":"Function of vitamin A in normal and synchronized seminiferous tubules","volume":"564","author":"Griswold","year":"1989","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"2019041121411706000_B10","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1095\/biolreprod56.2.549","article-title":"Retinoic acid receptor \u03b1 gene expression in the rat testis: potential role during the prophase of meiosis and in the transition from round to elongating spermatids","volume":"56","author":"Akmal","year":"1997","journal-title":"Biol Reprod"},{"issue":"1","key":"2019041121411706000_B11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1095\/biolreprod.107.066795","article-title":"Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes","volume":"79","author":"Zhou","year":"2008","journal-title":"Biol Reprod"},{"issue":"9","key":"2019041121411706000_B12","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1096\/fasebj.10.9.8801176","article-title":"A decade of molecular biology of retinoic acid receptors","volume":"10","author":"Chambon","year":"1996","journal-title":"FASEB J"},{"issue":"1","key":"2019041121411706000_B13","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1210\/en.2011-1102","article-title":"Spermatogonia differentiation requires retinoic acid receptor \u03b3","volume":"153","author":"Gely-Pernot","year":"2012","journal-title":"Endocrinology"},{"issue":"1","key":"2019041121411706000_B14","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0925-4773(95)00424-6","article-title":"Mice lacking all isoforms of retinoic acid receptor \u03b2 develop normally and are susceptible to the teratogenic effects of retinoic acid","volume":"53","author":"Luo","year":"1995","journal-title":"Mech Dev"},{"issue":"24","key":"2019041121411706000_B15","doi-asserted-by":"crossref","first-page":"5816","DOI":"10.1038\/sj.emboj.7601447","article-title":"Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells","volume":"25","author":"Vernet","year":"2006","journal-title":"EMBO J"},{"issue":"15","key":"2019041121411706000_B16","doi-asserted-by":"crossref","first-page":"7225","DOI":"10.1073\/pnas.90.15.7225","article-title":"High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice","volume":"90","author":"Lufkin","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"2019041121411706000_B17","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1002\/dvdy.20083","article-title":"Retinoic acid receptor \u03b1 is required for synchronization of spermatogenic cycles and its absence results in progressive breakdown of the spermatogenic process","volume":"230","author":"Chung","year":"2004","journal-title":"Dev Dyn"},{"issue":"4","key":"2019041121411706000_B18","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1432-0436.2005.00018.x","article-title":"Male sterility in mice lacking retinoic acid receptor \u03b1 involves specific abnormalities in spermiogenesis","volume":"73","author":"Chung","year":"2005","journal-title":"Differentiation"},{"issue":"1","key":"2019041121411706000_B19","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1196\/annals.1411.008","article-title":"Potential functions of retinoic acid receptor A in Sertoli cells and germ cells during spermatogenesis","volume":"1120","author":"Doyle","year":"2007","journal-title":"Ann N Y Acad Sci"},{"issue":"11","key":"2019041121411706000_B20","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1210\/mend-4-11-1679","article-title":"The regulation of retinoic acid receptor mRNA levels during spermatogenesis","volume":"4","author":"Kim","year":"1990","journal-title":"Mol Endocrinol"},{"issue":"5","key":"2019041121411706000_B21","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1210\/endo.140.5.6720","article-title":"Action of retinoids on embryonic and early postnatal testis development","volume":"140","author":"Cupp","year":"1999","journal-title":"Endocrinology"},{"issue":"5","key":"2019041121411706000_B22","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1095\/biolreprod61.5.1300","article-title":"Cellular and subcellular localization of six retinoid receptors in rat testis during postnatal development: identification of potential heterodimeric receptors","volume":"61","author":"Dufour","year":"1999","journal-title":"Biol Reprod"},{"issue":"6","key":"2019041121411706000_B23","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1095\/biolreprod61.6.1548","article-title":"Retinoic acid receptors and retinoid X receptors in the rat testis during fetal and postnatal development: immunolocalization and implication in the control of the number of gonocytes","volume":"61","author":"Boulogne","year":"1999","journal-title":"Biol Reprod"},{"issue":"2","key":"2019041121411706000_B24","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.stemcr.2018.01.003","article-title":"Testicular architecture is critical for mediation of retinoic acid responsiveness by undifferentiated spermatogonial subtypes in the mouse","volume":"10","author":"Lord","year":"2018","journal-title":"Stem Cell Reports"},{"key":"2019041121411706000_B25","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1749-6632.1991.tb27318.x","article-title":"Expression of receptors during the cycle of the seminiferous epithelium","volume":"637","author":"Linder","year":"1991","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"2019041121411706000_B26","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1095\/biolreprod.114.126326","article-title":"Processive pulses of retinoic acid propel asynchronous and continuous murine sperm production","volume":"92","author":"Hogarth","year":"2015","journal-title":"Biol Reprod"},{"issue":"24","key":"2019041121411706000_B27","doi-asserted-by":"crossref","first-page":"11298","DOI":"10.1073\/pnas.91.24.11298","article-title":"Spermatogenesis following male germ-cell transplantation","volume":"91","author":"Brinster","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041121411706000_B28","unstructured":"RRID:IMSR_JAX:006054."},{"key":"2019041121411706000_B29","unstructured":"RRID:IMSR_JAX:008208."},{"key":"2019041121411706000_B30","unstructured":"RRID:IMSR_JAX:006148."},{"issue":"1","key":"2019041121411706000_B31","first-page":"111","article-title":"Transplantation of testis germinal cells into mouse seminiferous tubules","volume":"41","author":"Ogawa","year":"1997","journal-title":"Int J Dev Biol"},{"issue":"6","key":"2019041121411706000_B32","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative CT method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat Protoc"},{"issue":"5","key":"2019041121411706000_B33","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1095\/biolreprod.112.101709","article-title":"Loss of occludin expression and impairment of blood-testis barrier permeability in rats with autoimmune orchitis: effect of interleukin 6 on Sertoli cell tight junctions","volume":"87","author":"P\u00e9rez","year":"2012","journal-title":"Biol Reprod"},{"issue":"1","key":"2019041121411706000_B34","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1023\/A:1018445520117","article-title":"A drying-down technique for the spreading of mammalian meiocytes from the male and female germline","volume":"5","author":"Peters","year":"1997","journal-title":"Chromosome Res"},{"key":"2019041121411706000_B35","unstructured":"RRID:AB_301637."},{"key":"2019041121411706000_B36","unstructured":"RRID:AB_309864."},{"issue":"9","key":"2019041121411706000_B37","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1002\/j.1460-2075.1993.tb06042.x","article-title":"Apoptotic death in epithelial cells: cleavage of DNA to 300 and\/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation","volume":"12","author":"Oberhammer","year":"1993","journal-title":"EMBO J"},{"issue":"5","key":"2019041121411706000_B38","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1095\/biolreprod.102.012575","article-title":"Functional assessment of self-renewal activity of male germline stem cells following cytotoxic damage and serial transplantation","volume":"68","author":"Kanatsu-Shinohara","year":"2003","journal-title":"Biol Reprod"},{"issue":"9","key":"2019041121411706000_B39","doi-asserted-by":"crossref","first-page":"e1006293","DOI":"10.1371\/journal.pgen.1006293","article-title":"DMRT1 is required for mouse spermatogonial stem cell maintenance and replenishment","volume":"12","author":"Zhang","year":"2016","journal-title":"PLoS Genet"},{"issue":"6","key":"2019041121411706000_B40","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/0092-8674(92)90250-G","article-title":"Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors","volume":"70","author":"Nagpal","year":"1992","journal-title":"Cell"},{"issue":"12","key":"2019041121411706000_B41","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/dvg.20437","article-title":"Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice","volume":"46","author":"Sadate-Ngatchou","year":"2008","journal-title":"Genesis"},{"key":"2019041121411706000_B42","unstructured":"RRID:AB_303395."},{"key":"2019041121411706000_B43","unstructured":"RRID:AB_2218932."},{"issue":"6","key":"2019041121411706000_B44","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/ng1367","article-title":"Essential role of Plzf in maintenance of spermatogonial stem cells","volume":"36","author":"Costoya","year":"2004","journal-title":"Nat Genet"},{"key":"2019041121411706000_B45","unstructured":"RRID:AB_2177750."},{"issue":"2","key":"2019041121411706000_B46","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1083\/jcb.135.2.469","article-title":"Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene","volume":"135","author":"Oulad-Abdelghani","year":"1996","journal-title":"J Cell Biol"},{"issue":"1","key":"2019041121411706000_B47","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1530\/REP-10-0431","article-title":"Spermatogonial morphology and kinetics during testis development in mice: a high-resolution light microscopy approach","volume":"142","author":"Drumond","year":"2011","journal-title":"Reproduction"},{"issue":"1","key":"2019041121411706000_B48","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/j.1939-4640.1982.tb00646.x","article-title":"Quantitative correlation between testicular stem cell survival, sperm production, and fertility in the mouse after treatment with different cytotoxic agents","volume":"3","author":"Meistrich","year":"1982","journal-title":"J Androl"},{"issue":"4","key":"2019041121411706000_B49","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/BF00292848","article-title":"Synaptonemal complex analysis of mouse chromosomal rearrangements. IV. Synapsis and synaptic adjustment in two paracentric inversions","volume":"84","author":"Moses","year":"1982","journal-title":"Chromosoma"},{"issue":"3","key":"2019041121411706000_B50","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/85830","article-title":"Recombinational DNA double-strand breaks in mice precede synapsis","volume":"27","author":"Mahadevaiah","year":"2001","journal-title":"Nat Genet"},{"issue":"Pt 10","key":"2019041121411706000_B51","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1242\/jcs.02362","article-title":"SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division","volume":"118","author":"Kouznetsova","year":"2005","journal-title":"J Cell Sci"},{"issue":"1","key":"2019041121411706000_B52","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/(SICI)1097-0177(199701)208:1<125::AID-AJA12>3.0.CO;2-5","article-title":"Morphological analysis of germ cell apoptosis during postnatal testis development in normal and Hsp70-2 knockout mice","volume":"208","author":"Mori","year":"1997","journal-title":"Dev Dyn"},{"issue":"1","key":"2019041121411706000_B53","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1530\/REP-06-0148","article-title":"Aging does not affect spermatogenic recovery after experimentally induced injury in mice","volume":"133","author":"Ehmcke","year":"2007","journal-title":"Reproduction"},{"issue":"1","key":"2019041121411706000_B54","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1093\/humrep\/der357","article-title":"The efficiency of male fertility restoration is dependent on the recovery kinetics of spermatogonial stem cells after cytotoxic treatment with busulfan in mice","volume":"27","author":"Zohni","year":"2012","journal-title":"Hum Reprod"},{"issue":"1546","key":"2019041121411706000_B55","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1098\/rstb.2009.0251","article-title":"Sertoli\u2013germ cell junctions in the testis: a review of recent data","volume":"365","author":"Kopera","year":"2010","journal-title":"Philos Trans R Soc Lond B Biol Sci."},{"issue":"4","key":"2019041121411706000_B56","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1083\/jcb.200704061","article-title":"A seamless trespass: germ cell migration across the seminiferous epithelium during spermatogenesis","volume":"178","author":"Wang","year":"2007","journal-title":"J Cell Biol"},{"issue":"Pt 3","key":"2019041121411706000_B57","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1242\/jcs.131946","article-title":"Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts","volume":"127","author":"Al Tanoury","year":"2014","journal-title":"J Cell Sci"},{"issue":"1","key":"2019041121411706000_B58","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1159\/000146606","article-title":"Disruption of sustentacular (Sertoli) cell tight junctions and regression of spermatogenesis in vitamin-A-deficient rats","volume":"133","author":"Huang","year":"1988","journal-title":"Acta Anat (Basel)"},{"issue":"1","key":"2019041121411706000_B59","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1095\/biolreprod.115.131458","article-title":"ALDH enzyme expression is independent of the spermatogenic cycle, and their inhibition causes misregulation of murine spermatogenic processes","volume":"94","author":"Kent","year":"2016","journal-title":"Biol Reprod"},{"issue":"3","key":"2019041121411706000_B60","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/aja.1000990307","article-title":"Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium","volume":"99","author":"Oakberg","year":"1956","journal-title":"Am J Anat"},{"issue":"2","key":"2019041121411706000_B61","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/aja.1001110202","article-title":"Quantitative analysis of spermatogenesis of the rat: a revised model for the renewal of spermatogonia","volume":"111","author":"Clermont","year":"1962","journal-title":"Am J Anat"},{"issue":"3","key":"2019041121411706000_B62","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/ng0398-257","article-title":"The meiotic checkpoint monitoring synapsis eliminates spermatocytes via p53-independent apoptosis","volume":"18","author":"Odorisio","year":"1998","journal-title":"Nat Genet"},{"issue":"3","key":"2019041121411706000_B63","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1095\/biolreprod.113.114645","article-title":"Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse","volume":"90","author":"Busada","year":"2014","journal-title":"Biol Reprod"},{"issue":"5","key":"2019041121411706000_B64","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.stem.2008.08.002","article-title":"Homing of mouse spermatogonial stem cells to germline niche depends on \u03b21-integrin","volume":"3","author":"Kanatsu-Shinohara","year":"2008","journal-title":"Cell Stem Cell"},{"issue":"5","key":"2019041121411706000_B65","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.stem.2011.08.011","article-title":"Rac mediates mouse spermatogonial stem cell homing to germline niches by regulating transmigration through the blood-testis barrier","volume":"9","author":"Takashima","year":"2011","journal-title":"Cell Stem Cell"},{"issue":"2","key":"2019041121411706000_B66","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ydbio.2014.02.013","article-title":"CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways","volume":"389","author":"Saba","year":"2014","journal-title":"Dev Biol"},{"issue":"8","key":"2019041121411706000_B67","doi-asserted-by":"crossref","first-page":"e1004541","DOI":"10.1371\/journal.pgen.1004541","article-title":"Retinoic acid activates two pathways required for meiosis in mice","volume":"10","author":"Koubova","year":"2014","journal-title":"PLoS Genet"},{"issue":"6","key":"2019041121411706000_B68","doi-asserted-by":"crossref","first-page":"901","DOI":"10.15252\/embr.201642030","article-title":"High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation","volume":"17","author":"Agostinho","year":"2016","journal-title":"EMBO Rep"}],"container-title":["Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/endo\/article-pdf\/159\/9\/3403\/25595333\/en.2018-00533.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T06:47:10Z","timestamp":1555051630000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/endo\/article\/159\/9\/3403\/5066498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,6]]},"references-count":68,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2018,8,6]]},"published-print":{"date-parts":[[2018,9,1]]}},"URL":"https:\/\/doi.org\/10.1210\/en.2018-00533","relation":{},"ISSN":["1945-7170"],"issn-type":[{"value":"1945-7170","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,9]]},"published":{"date-parts":[[2018,8,6]]}}}