{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T22:15:36Z","timestamp":1783548936697,"version":"3.55.0"},"reference-count":82,"publisher":"The Endocrine Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,12,1]]},"DOI":"10.1210\/endo.141.12.7817","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T16:10:53Z","timestamp":1389197453000},"page":"4533-4542","source":"Crossref","is-referenced-by-count":42,"title":["ADAMTS-1: A Cellular Disintegrin and Metalloprotease with Thrombospondin Motifs Is a Target for Parathyroid Hormone in Bone"],"prefix":"10.1210","volume":"141","author":[{"given":"R. R.","family":"Miles","sequence":"first","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. P.","family":"Sluka","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. L.","family":"Halladay","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. F.","family":"Santerre","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. V.","family":"Hale","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Bloem","sequence":"additional","affiliation":[{"name":"Cardiovascular Division (L.B.), Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Thirunavukkarasu","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. J. S.","family":"Galvin","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Hock","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. E.","family":"Onyia","sequence":"additional","affiliation":[{"name":"Endocrine Division (R.R.M., J.P.S., D.L.H., R.F.S., L.V.H., K.T., R.J.S.G., J.M.H., J.E.O.) Lilly Research Laboratories, Indianapolis, Indiana 46285"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"2019041121415128600_R1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S8756-3282(99)00166-0","article-title":"Effect of treatment for 6 months with human parathyroid hormone (1\u201334) peptide in ovariectomized cynomolgus monkeys (Macaca fascicularis).","volume":"25","author":"Jerome","year":"1999","journal-title":"Bone"},{"key":"2019041121415128600_R2","first-page":"690","article-title":"Anabolic actions of parathyroid hormone on bone.","volume":"14","author":"Dempster","year":"1993","journal-title":"Endocr Rev"},{"key":"2019041121415128600_R3","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1210\/endo-122-6-2899","article-title":"Human parathyroid hormone-(1\u201334) increases bone mass in ovariectomized and orchidectomized rats.","volume":"122","author":"Hock","year":"1989","journal-title":"Endocrinology"},{"key":"2019041121415128600_R4","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1210\/endo-125-4-2022","article-title":"Comparison of the anabolic effects of synthetic parathyroid hormone-related protein (PTHrP) 1\u201334 and PTH 1\u201334 on bone in rats.","volume":"125","author":"Hock","year":"1989","journal-title":"Endocrinology"},{"key":"2019041121415128600_R5","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/jbmr.5650070110","article-title":"Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone.","volume":"7","author":"Hock","year":"1992","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R6","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/jbmr.5650040321","article-title":"Resorption is not essential for stimulation of bone growth by hPTH-(1\u201334) in rats in vivo.","volume":"4","author":"Hock","year":"1989","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R7","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/BF03549782","article-title":"Parathyroid hormone (1\u201334) and (1\u201384) stimulate cortical bone formation both from periosteum and endosteum.","volume":"53","author":"Oxlund","year":"1993","journal-title":"Calcif Tissue Int"},{"key":"2019041121415128600_R8","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1136\/bmj.280.6228.1340","article-title":"Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicenter trial.","volume":"280","author":"Reeve","year":"1980","journal-title":"Br Med J"},{"key":"2019041121415128600_R9","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1056\/NEJM199208273270908","article-title":"The prevention and treatment of osteoporosis.","volume":"327","author":"Riggs","year":"1992","journal-title":"N Engl J Med"},{"key":"2019041121415128600_R10","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1172\/JCI110372","article-title":"Short-term effects of synthetic human parathyroid hormone-(1\u201334) administration on bone mineral metabolism in osteoporotic patients.","volume":"68","author":"Slovik","year":"1981","journal-title":"J Clin Invest"},{"key":"2019041121415128600_R11","first-page":"S412","article-title":"Anabolic PTH targets proliferating cells of the primary spongiosa in young rats, and increases the number differentiating into osteoblasts","volume":"9","author":"Hock","year":"1994","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R12","doi-asserted-by":"crossref","first-page":"5127","DOI":"10.1210\/endo.136.11.7588250","article-title":"Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats.","volume":"136","author":"Schmidt","year":"1995","journal-title":"Endocrinology"},{"key":"2019041121415128600_R13","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1007\/BF03354654","article-title":"Comparisons of in vivo and in vitro models of the response of osteoblasts to hormonal regulation with aging","volume":"56","author":"Hock","year":"1995","journal-title":"Calcif Tissue Int"},{"key":"2019041121415128600_R14","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/8756-3282(95)00332-2","article-title":"In vivo, human parathyroid hormone fragment (hPTH 1\u201334) transiently stimulates immediate early response gene expression but not proliferation in trabecular bone cells of young rats.","volume":"17","author":"Onyia","year":"1995","journal-title":"Bone"},{"key":"2019041121415128600_R15","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S8756-3282(96)00350-X","article-title":"Proliferating cells in the primary spongiosa express osteoblastic phenotype in vitro.","volume":"20","author":"Onyia","year":"1997","journal-title":"Bone"},{"key":"2019041121415128600_R16","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1210\/endo.134.1.8275957","article-title":"Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: in situ localization of its receptor and c-fos messenger ribonucleic acids.","volume":"134","author":"Lee","year":"1994","journal-title":"Endocrinology"},{"key":"2019041121415128600_R17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s002239900715","article-title":"Immunohistochemical localization of selected early response genes expressed in trabecular bone of young rats given hPTH1\u201334.","volume":"65","author":"Liang","year":"1999","journal-title":"Calcif Tissue Int"},{"key":"2019041121415128600_R18","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1210\/endo.141.1.7229","article-title":"Dynamic regulation of RGS2 in bone: potential new insights into parathroid hormone signaling mechanism.","volume":"141","author":"Miles","year":"2000","journal-title":"Endocrinology"},{"key":"2019041121415128600_R19","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1002\/jbmr.5650110606","article-title":"In vivo demonstration that parathyroid hormone and parathyroid hormone-related protein stimulate expression by osteoblasts of interleukin-6 and leukemia inhibitory factor.","volume":"11","author":"Pollock","year":"1996","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0047-6374(99)00002-0","article-title":"Expression of the c-fos gene induced by parathyroid hormone in the bones of SAMP6 mice, a murine model for senile osteoporosis.","volume":"108","author":"Takeda","year":"1999","journal-title":"Mech Ageing Dev"},{"key":"2019041121415128600_R21","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/S0955-0674(98)80042-2","article-title":"ADAMs: focus on the protease domain.","volume":"10","author":"Black","year":"1998","journal-title":"Curr Opin Cell Biol"},{"key":"2019041121415128600_R22","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/S0092-8674(00)80519-X","article-title":"Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF\u03b1 and Notch.","volume":"90","author":"Blobel","year":"1997","journal-title":"Cell"},{"key":"2019041121415128600_R23","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1038\/21196","article-title":"Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans.","volume":"399","author":"Blelloch","year":"1999","journal-title":"Nature"},{"key":"2019041121415128600_R24","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1042\/bst0270255","article-title":"Role for ADAM-family proteinases as membrane protein secretases.","volume":"27","author":"Turner","year":"1999","journal-title":"Biochem Soc Trans"},{"key":"2019041121415128600_R25","first-page":"1453","article-title":"ADAM family proteins and cell fusion.","volume":"68","author":"Endo","year":"1996","journal-title":"Seikagaku"},{"key":"2019041121415128600_R26","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/S0955-0674(96)80111-6","article-title":"ADAMs and cell fusion.","volume":"8","author":"Huovila","year":"1996","journal-title":"Curr Opin Cell Biol"},{"key":"2019041121415128600_R27","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1590\/S0100-879X1998000700001","article-title":"Snake venom metalloproteinases and disintegrins: interactions with cells.","volume":"31","author":"Kamiguti","year":"1998","journal-title":"Brazilian J Med Biol Res"},{"key":"2019041121415128600_R28","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/S0167-5699(99)01464-4","article-title":"ADAM family proteins in the immune system.","volume":"20","author":"Yamamoto","year":"1999","journal-title":"Immunol Today"},{"key":"2019041121415128600_R29","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1042\/bst0270224","article-title":"Interleukin-6 receptor shedding: a possible role for members of the ADAM family.","volume":"27","author":"Croucher","year":"1999","journal-title":"Biochem Soc Trans"},{"key":"2019041121415128600_R30","doi-asserted-by":"crossref","first-page":"4180","DOI":"10.1074\/jbc.273.7.4180","article-title":"Cloning and initial characterization of mouse meltrin \u03b2 and analysis of the expression of four metalloprotease-disintegrins in bone cells.","volume":"273","author":"Inoue","year":"1998","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S8756-3282(99)00099-X","article-title":"Localization of ADAM10 and Notch receptors in bone.","volume":"25","author":"Dallas","year":"1999","journal-title":"Bone"},{"key":"2019041121415128600_R32","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1074\/jbc.272.1.556","article-title":"Molecular cloning of a gene encoding a new type of metalloproteinase- disintegrin family protein with thrombospondin motifs as an inflammation associated gene.","volume":"272","author":"Kuno","year":"1997","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R33","doi-asserted-by":"crossref","first-page":"23443","DOI":"10.1074\/jbc.274.33.23443","article-title":"Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family.","volume":"274","author":"Abbaszade","year":"1999","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R34","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1126\/science.284.5420.1664","article-title":"Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.","volume":"284","author":"Tortorella","year":"1999","journal-title":"Science"},{"key":"2019041121415128600_R35","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0014-5793(99)00119-2","article-title":"ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.","volume":"445","author":"Tang","year":"1999","journal-title":"FEBS Lett"},{"key":"2019041121415128600_R36","doi-asserted-by":"crossref","first-page":"25555","DOI":"10.1074\/jbc.274.36.25555","article-title":"ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.","volume":"274","author":"Hurskainen","year":"1999","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R37","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1073\/pnas.94.6.2374","article-title":"cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components.","volume":"94","author":"Colige","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041121415128600_R38","doi-asserted-by":"crossref","first-page":"13912","DOI":"10.1074\/jbc.273.22.13912","article-title":"ADAMTS-1 protein anchors at the extracellular matrix through the thrombospondin type I motifs and its spacing region.","volume":"273","author":"Kuno","year":"1998","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R39","doi-asserted-by":"crossref","first-page":"18821","DOI":"10.1074\/jbc.274.26.18821","article-title":"ADAMTS-1 is an active metalloproteinase associated with the extracellular matrix.","volume":"274","author":"Kuno","year":"1999","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R40","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1086\/302504","article-title":"Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene.","volume":"65","author":"Colige","year":"1999","journal-title":"Am J Hum Genet"},{"key":"2019041121415128600_R41","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/(SICI)1097-4644(19980901)70:3<391::AID-JCB12>3.0.CO;2-O","article-title":"Intermittent administration of parathyroid hormone (1\u201334) stimulates matrix metalloproteinase-9 (MMP-9) expression in rat long bone.","volume":"70","author":"McClelland","year":"1998","journal-title":"J Cell Biochem"},{"key":"2019041121415128600_R42","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/BF02554834","article-title":"The effects of prostaglandin E2 in growing rats: increased metaphyseal hard tissue and cortico-endosteal bone formation.","volume":"37","author":"Jee","year":"1985","journal-title":"Calcif Tissue Int"},{"key":"2019041121415128600_R43","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S8756-3282(97)00011-2","article-title":"Systemic administration of an anabolic dose of prostaglandin E2 induces early-response genes in rat bones.","volume":"20","author":"Weinreb","year":"1997","journal-title":"Bone"},{"key":"2019041121415128600_R44","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1210\/endo.137.6.8641199","article-title":"A role for CD8+ T lymphocytes in osteoclast differentiation in vitro.","volume":"137","author":"John","year":"1996","journal-title":"Endocrinology"},{"key":"2019041121415128600_R45","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1210\/endo.138.1.4852","article-title":"Rat osteoblast and osteosarcoma nuclear matrix proteins bind with sequence specificity to the rat type I collagen promoter.","volume":"138","author":"Alvarez","year":"1997","journal-title":"Endocrinology"},{"key":"2019041121415128600_R46","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1359\/jbmr.1998.13.1.20","article-title":"Osteoprogenitor cells as targets for ex vivo gene transfer.","volume":"13","author":"Onyia","year":"1998","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R47","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1006\/bbrc.1999.1632","article-title":"TGF-\u03b2 enhances osteoclast differentiation in hematopoietic cell cultures stimulated with RANKL and M-CSF.","volume":"265","author":"Sells Galvin","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"2019041121415128600_R48","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1126\/science.1354393","article-title":"Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction.","volume":"257","author":"Liang","year":"1992","journal-title":"Science"},{"key":"2019041121415128600_R49","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1006\/bbrc.1998.9517","article-title":"Limitations of differential display.","volume":"251","author":"Ledakis","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"2019041121415128600_R50","doi-asserted-by":"crossref","first-page":"138","DOI":"10.2144\/98251rr02","article-title":"Elimination of false positives generated through PCR re-amplification of differential display cDNA.","volume":"25","author":"Miele","year":"1998","journal-title":"BioTechniques"},{"key":"2019041121415128600_R51","doi-asserted-by":"crossref","first-page":"462","DOI":"10.2144\/97233st03","article-title":"Use of two reverse transcriptases eliminates false-positive results in differential display.","volume":"23","author":"Sung","year":"1997","journal-title":"BioTechniques"},{"key":"2019041121415128600_R52","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/0165-6147(96)40001-3","article-title":"mRNA differential display: application in the discovery of novel pharmacological targets.","volume":"17","author":"Wang","year":"1996","journal-title":"Trends Pharmacol Sci"},{"key":"2019041121415128600_R53","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/S0008-6363(97)00169-7","article-title":"The use of mRNA differential display for discovery of novel therapeutic targets in cardiovascular disease.","volume":"35","author":"Wang","year":"1997","journal-title":"Cardiovasc Res"},{"key":"2019041121415128600_R54","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1210\/endo.130.1.1727705","article-title":"Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells.","volume":"130","author":"Fujimori","year":"1992","journal-title":"Endocrinology"},{"key":"2019041121415128600_R55","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1210\/endo-128-6-3032","article-title":"Dissociation of second messenger activation by parathyroid hormone fragments in osteosarcoma cells.","volume":"128","author":"Fujimori","year":"1991","journal-title":"Endocrinology"},{"key":"2019041121415128600_R56","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1210\/endo.130.1.1727720","article-title":"The protein kinase-C activation domain of the parathyroid hormone.","volume":"130","author":"Jouishomme","year":"1992","journal-title":"Endocrinology"},{"key":"2019041121415128600_R57","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1002\/jbmr.5650090620","article-title":"Further definition of the protein kinase C activation domain of the parathyroid hormone.","volume":"9","author":"Jouishomme","year":"1994","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R58","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1002\/jbmr.5650090807","article-title":"Parathyroid hormone fragments may stimulate bone growth in ovariectomized rats by activating adenylyl cyclase.","volume":"9","author":"Rixon","year":"1994","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R59","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1126\/science.1658941","article-title":"A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.","volume":"254","author":"Juppner","year":"1991","journal-title":"Science"},{"key":"2019041121415128600_R60","doi-asserted-by":"crossref","first-page":"8557","DOI":"10.1016\/S0021-9258(18)68339-5","article-title":"The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma membrane of ROS 17\/2.8 cells.","volume":"263","author":"Juppner","year":"1988","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R61","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1210\/endo-108-1-213","article-title":"Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells.","volume":"108","author":"Partridge","year":"1981","journal-title":"Endocrinology"},{"key":"2019041121415128600_R62","first-page":"4308","article-title":"Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin.","volume":"43","author":"Partridge","year":"1983","journal-title":"Cancer Res"},{"key":"2019041121415128600_R63","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF02557679","article-title":"Characterization of an osteoblast-like clonal cell line which responds to both parathyroid hormone and calcitonin.","volume":"37","author":"Forrest","year":"1985","journal-title":"Calcif Tissue Int"},{"key":"2019041121415128600_R64","first-page":"2153","article-title":"Parathyroid hormone induces transcription of collagenase in rat osteoblastic cells by a mechanism utilizing cAMP and requiring protein synthesis.","volume":"6","author":"Scott","year":"1992","journal-title":"Mol Endocrinol"},{"key":"2019041121415128600_R65","doi-asserted-by":"crossref","first-page":"23349","DOI":"10.1074\/jbc.274.33.23349","article-title":"METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.","volume":"274","author":"Vazquez","year":"1999","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R66","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1210\/endo.139.10.6261","article-title":"Type-1 parathyroid hormone (PTH)\/PTH- related peptide (PTHrP) receptors activate phospholipase C in response to carboxyl-truncated analogs of PTH(1\u201334).","volume":"139","author":"Takasu","year":"1998","journal-title":"Endocrinology"},{"key":"2019041121415128600_R67","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/jcb.240550308","article-title":"Signal-transduction pathways mediating parathyroid hormone regulation of osteoblastic gene expression.","volume":"55","author":"Partridge","year":"1994","journal-title":"J Cell Biochem"},{"key":"2019041121415128600_R68","doi-asserted-by":"crossref","first-page":"18574","DOI":"10.1016\/S0021-9258(19)81398-4","article-title":"Cyclic AMP-mediated stabilization of osteocalcin mRNA in rat osteoblast-like cells treated with parathyroid hormone.","volume":"263","author":"Noda","year":"1988","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R69","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1083\/jcb.108.2.713","article-title":"Transcriptional regulation of osteopontin production in rat osteoblast-like cells by parathyroid hormone.","volume":"108","author":"Noda","year":"1989","journal-title":"J Cell Biol"},{"key":"2019041121415128600_R70","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.1210\/endo.138.8.5315","article-title":"Parathyroid hormone (PTH 1\u201334) regulation of rat osteocalcin gene transcription.","volume":"138","author":"Yu","year":"1997","journal-title":"Endocrinology"},{"key":"2019041121415128600_R71","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1074\/jbc.275.2.999","article-title":"Activation of osteocalcin transcription involves interaction of protein kinase A- and protein kinase C-dependent pathways.","volume":"275","author":"Boguslawski","year":"2000","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R72","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1359\/jbmr.2000.15.5.863","article-title":"In vivo demonstration that parathyroid hormone (hPTH 1\u201338) inhibits the expression of osteoprotegerin (OPG) in bone with the kinetics of an immediate early gene.","volume":"15","author":"Onyia","year":"2000","journal-title":"J Bone Miner Res"},{"key":"2019041121415128600_R73","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S8756-3282(98)00115-X","article-title":"Parathyroid hormone induces interleukin-6 heterogeneous nuclear and messenger RNA expression in murine calvarial organ cultures.","volume":"23","author":"Huang","year":"1998","journal-title":"Bone"},{"key":"2019041121415128600_R74","first-page":"1834","article-title":"Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells.","volume":"6","author":"Clohisy","year":"1992","journal-title":"Mol Endocrinol"},{"key":"2019041121415128600_R75","doi-asserted-by":"crossref","first-page":"10984","DOI":"10.1074\/jbc.271.18.10984","article-title":"Stimulation by parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction.","volume":"271","author":"Greenfield","year":"1996","journal-title":"J Biol Chem"},{"key":"2019041121415128600_R76","doi-asserted-by":"crossref","first-page":"5435","DOI":"10.1210\/endo.137.12.8940368","article-title":"Parathyroid hormone induces prostaglandin G\/H synthase-2 expression by a cyclic adenosine 3\u2032,5\u2032-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3\u2013E1.","volume":"137","author":"Tetradis","year":"1996","journal-title":"Endocrinology"},{"key":"2019041121415128600_R77","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2165\/00002512-199915020-00005","article-title":"The bone-building action of the parathyroid hormone: implications for the treatment of osteoporosis [Review].","volume":"15","author":"Whitfield","year":"1999","journal-title":"Drugs Aging"},{"key":"2019041121415128600_R78","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1016\/0006-291X(92)91882-Q","article-title":"The activation of cAMP-dependent protein kinase is directly linked to the stimulation of bone resorption by parathyroid hormone.","volume":"182","author":"Kaji","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"2019041121415128600_R79","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1006\/bbrc.1993.1699","article-title":"The cyclic-AMP antagonist adenosine-3\u2032,5\u2032-cyclic monophosphosphorothioate, RP-isomer inhibits parathyroid hormone induced bone resorption, in vitro.","volume":"193","author":"Ljunggren","year":"1993","journal-title":"Biochem Biophys Res Commun"},{"key":"2019041121415128600_R80","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1172\/JCI118157","article-title":"Adenyl cyclase and interleukin 6 are downstream effectors of parathyroid hormone resulting in stimulation of bone resorption.","volume":"96","author":"Greenfield","year":"1995","journal-title":"J Clin Invest"},{"key":"2019041121415128600_R81","doi-asserted-by":"crossref","first-page":"4689","DOI":"10.1073\/pnas.080073497","article-title":"Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases.","volume":"97","author":"Robker","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041121415128600_R82","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1095\/biolreprod62.4.1090","article-title":"Ovarian expression of a disintegrin and metalloproteinase with thrombospondin motifs during ovulation in the gonadotropin-primed immature rat.","volume":"62","author":"Espey","year":"2000","journal-title":"Biol Reprod"}],"container-title":["Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/endo\/article-pdf\/141\/12\/4533\/10359168\/endo4533.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T23:14:41Z","timestamp":1647904481000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/endo\/article\/141\/12\/4533\/2988239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,12,1]]},"references-count":82,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2000,12,1]]}},"URL":"https:\/\/doi.org\/10.1210\/endo.141.12.7817","relation":{},"ISSN":["0013-7227","1945-7170"],"issn-type":[{"value":"0013-7227","type":"print"},{"value":"1945-7170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,12,1]]}}}