{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:16:34Z","timestamp":1768266994431,"version":"3.49.0"},"reference-count":46,"publisher":"The Endocrine Society","issue":"7","license":[{"start":{"date-parts":[[2020,4,25]],"date-time":"2020-04-25T00:00:00Z","timestamp":1587772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hypoparathyroidism during pregnancy is a very rare endocrine disorder. The majority of cases are postsurgical (75%). Managing pregnant or nursing women with hypoparathyroidism is challenging due to complications arising from either under- or overtreatment, including premature delivery or fetal death, abortion, stillbirth, perinatal death, and neonatal tetany. Specific adaptations are needed within each time period to meet the fetal, neonatal, and maternal calcium requirements. A systematic search was performed on PubMed using the search terms \u201cpregnancy\u201d and \u201chypoparathyroidism.\u201d Included were articles published in English between January 1, 1966, and January 1, 2018. We provide an overview of all published cases (n\u2005=\u200543) of hypoparathyroidism in pregnancy, including a case report of a 29-year-old pregnant woman who underwent a total thyroidectomy before her current pregnancy because of a therapy-resistantant Graves\u2019 disease. The procedure was complicated by postsurgical hypoparathyroidism. She carried out the pregnancy to term with minor complaints of paresthesia and muscle cramps. Furthermore, we discuss treatment, complications, and follow-up of hypoparathyroidism in pregnancy. Treatment of hypoparathyroidism in pregnancy should still be individualized, depending on the patient\u2019s complaints and serum levels of calcium, which should be maintained in the lower normal range of 2.15 to 2.55 mmol\/l, according to the literature. We recommend monitoring calcium levels every 3 to 4 weeks throughout the pregnancy, within 1 week postpartum, and monthly during lactation to ensure normocalcemia.<\/jats:p>","DOI":"10.1210\/endocr\/bqaa067","type":"journal-article","created":{"date-parts":[[2020,4,25]],"date-time":"2020-04-25T18:05:59Z","timestamp":1587837959000},"source":"Crossref","is-referenced-by-count":6,"title":["Hypocalcemia After Thyroidectomy and Parathyroidectomy in a Pregnant Woman"],"prefix":"10.1210","volume":"161","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1830-4884","authenticated-orcid":false,"given":"Benjamin","family":"Lebrun","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, UZA Antwerp University Hospital, Edegem, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0679-3203","authenticated-orcid":false,"given":"Christophe","family":"De Block","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism, UZA Antwerp University Hospital, Edegem, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3172-5672","authenticated-orcid":false,"given":"Yves","family":"Jacquemyn","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, UZA Antwerp University Hospital, Edegem, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2020,4,25]]},"reference":[{"issue":"12","key":"2021121822170009200_CIT0001","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1002\/jbmr.2004","article-title":"Prevalence and incidence of hypoparathyroidism in the United States using a large claims database","volume":"28","author":"Powers","year":"2013","journal-title":"J Bone Miner Res."},{"key":"2021121822170009200_CIT0002","first-page":"8316017","article-title":"Idiopathic Hypoparathyroidism and Severe Hypocalcemia in Pregnancy","volume":"2018","author":"Richa","year":"2018","journal-title":"Case Rep Endocrinol."},{"key":"2021121822170009200_CIT0003","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bonr.2015.05.005","article-title":"Management of hypoparathyroidism in pregnancy and lactation - 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