{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:31:45Z","timestamp":1790274705810,"version":"4.1.0"},"reference-count":69,"publisher":"The Endocrine Society","issue":"11","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1004100"],"award-info":[{"award-number":["2018YFC1004100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFC1000200"],"award-info":[{"award-number":["2016YFC1000200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFC1000400"],"award-info":[{"award-number":["2016YFC1000400"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFC1001400"],"award-info":[{"award-number":["2016YFC1001400"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Uterine surgical scarring is an increasing risk factor for adverse pregnant consequences that threaten fetal-maternal health. The detailed molecular features of scar implantation remain largely unknown. We aim to study the pathologic features of uterine surgical scarring and the mechanisms of compromised pregnancy outcomes of scar implantation. We generated a mouse model of uterine surgical scarring with a uterine incision penetrating the myometrium to endometrium to examine the pathologic changes and transcriptome profiles of uterine scarring at various postsurgery (PS) time points, as well as features of the feto-maternal interface during scar implantation. We found that uterine surgical scar recovery was consistently poor at PS3 until PS90, as shown by a reduced number of endometrial glands, inhibition of myometrial smooth muscle cell growth but excessive collagen fiber deposition, and massive leukocyte infiltration. Transcriptome annotation indicated significant chronic inflammation at the scarring site. At the peri-implantation and postimplantation stages, abnormal expression of various steroid-responsive genes at the scarring site was in parallel with lumen epithelial cell hyperplasia, inappropriate luminal closure, and disorientation of the implanted embryo, restricted stromal cell proliferation, and defective decidualization. High embryonic lethality (around 70%) before E10.5 was observed, and the small amount of survival embryos at E10.5 exhibited restricted growth and aberrant placenta defects including overinvasion of trophoblast cells into the decidua and insufficient fetal blood vessel branching in the labyrinth. The findings indicate that chronic inflammation and compromised responses to steroids in uterine scar tissues are the pivotal molecular basis for adverse pregnancy consequences of scar implantation.<\/jats:p>","DOI":"10.1210\/endocr\/bqaa174","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T18:24:47Z","timestamp":1601058287000},"source":"Crossref","is-referenced-by-count":18,"title":["Uterine Scarring Leads to Adverse Pregnant Consequences by Impairing the Endometrium Response to Steroids"],"prefix":"10.1210","volume":"161","author":[{"given":"Zhilang","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotao","family":"Bian","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeling","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentong","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feiyang","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Xia","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0352-1648","authenticated-orcid":false,"given":"Xuan","family":"Shao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9448-7803","authenticated-orcid":false,"given":"Yan-Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2020,9,25]]},"reference":[{"issue":"9713","key":"2021121718173794800_CIT0001","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/S0140-6736(09)61870-5","article-title":"Method of delivery and pregnancy outcomes in Asia: the WHO global survey on maternal and perinatal health 2007-08","volume":"375","author":"Lumbiganon","year":"2010","journal-title":"Lancet."},{"issue":"4","key":"2021121718173794800_CIT0002","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/j.1365-3016.1996.tb00062.x","article-title":"Impact of caesarean section on future pregnancy\u2014a review of cohort studies","volume":"10","author":"Hemminki","year":"1996","journal-title":"Paediatr Perinat Epidemiol."},{"issue":"3","key":"2021121718173794800_CIT0003","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0028-2243(93)90064-J","article-title":"Placenta praevia and accreta after previous caesarean section","volume":"52","author":"Chattopadhyay","year":"1993","journal-title":"Eur J Obstet Gynecol Reprod Biol."},{"issue":"1","key":"2021121718173794800_CIT0004","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/uog.5200","article-title":"Deficient lower-segment Cesarean section scars: prevalence and risk factors","volume":"31","author":"Ofili-Yebovi","year":"2008","journal-title":"Ultrasound Obstet Gynecol."},{"issue":"1","key":"2021121718173794800_CIT0005","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00404-010-1598-7","article-title":"Critical analysis of risk factors and outcome of placenta previa","volume":"284","author":"Rosenberg","year":"2011","journal-title":"Arch Gynecol Obstet."},{"issue":"6","key":"2021121718173794800_CIT0006","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1093\/humrep\/det110","article-title":"Does the presence of a Caesarean section scar affect implantation site and early pregnancy outcome in women attending an early pregnancy assessment unit?","volume":"28","author":"Naji","year":"2013","journal-title":"Hum Reprod."},{"issue":"4","key":"2021121718173794800_CIT0007","doi-asserted-by":"crossref","first-page":"e10287","DOI":"10.1371\/journal.pone.0010287","article-title":"Natural selection of human embryos: impaired decidualization of endometrium disables embryo-maternal interactions and causes recurrent pregnancy loss","volume":"5","author":"Salker","year":"2010","journal-title":"PLoS One."},{"issue":"1","key":"2021121718173794800_CIT0008","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ijgo.2009.02.019","article-title":"Effect of cesarean delivery on the endometrium","volume":"106","author":"Ben-Nagi","year":"2009","journal-title":"Int J Gynaecol Obstet."},{"issue":"5","key":"2021121718173794800_CIT0009","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/uog.11133","article-title":"Does the presence of a cesarean section scar influence the site of placental implantation and subsequent migration in future pregnancies: a prospective case-control study","volume":"40","author":"Naji","year":"2012","journal-title":"Ultrasound Obstet Gynecol."},{"issue":"5","key":"2021121718173794800_CIT0010","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/j.1365-2613.2010.00718.x","article-title":"Effects of long-term diabetes on the structure and cell proliferation of the myometrium in the early pregnancy of mice","volume":"91","author":"Favaro","year":"2010","journal-title":"Int J Exp Pathol."},{"issue":"2","key":"2021121718173794800_CIT0011","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ajog.2005.07.048","article-title":"Uterine dehiscence in term pregnant patients with one previous cesarean delivery: growth factor immunoexpression and collagen content in the scarred lower uterine segment","volume":"194","author":"Pollio","year":"2006","journal-title":"Am J Obstet Gynecol."},{"issue":"2","key":"2021121718173794800_CIT0012","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2174\/1389203717666160322145939","article-title":"Uterine wound healing: a complex process mediated by proteins and peptides","volume":"18","author":"Lofrumento","year":"2017","journal-title":"Curr Protein Pept Sci."},{"key":"2021121718173794800_CIT0013","article-title":"Data from: Uterine scar leads to adverse pregnant consequence through impairing the response of endometrium to steroids","author":"Li"},{"key":"2021121718173794800_CIT0014","volume-title":"RRID: AB"},{"key":"2021121718173794800_CIT0015","volume-title":"RRID: AB_2783822,"},{"key":"2021121718173794800_CIT0016","volume-title":"RRID: AB_442810,"},{"key":"2021121718173794800_CIT0017","volume-title":"RRID: AB_369097,"},{"key":"2021121718173794800_CIT0018","volume-title":"RRID: AB_443209,"},{"key":"2021121718173794800_CIT0019","volume-title":"RRID: AB_301891,"},{"key":"2021121718173794800_CIT0020","volume-title":"RRID: AB_2291471,"},{"key":"2021121718173794800_CIT0021","volume-title":"RRID: AB_2571729,"},{"key":"2021121718173794800_CIT0022","volume-title":"RRID: AB_2797144,"},{"key":"2021121718173794800_CIT0023","volume-title":"RRID: AB_2868453,"},{"key":"2021121718173794800_CIT0024","volume-title":"RRID: AB_2868454,"},{"key":"2021121718173794800_CIT0025","volume-title":"RRID: AB_2868452,"},{"key":"2021121718173794800_CIT0026","volume-title":"RRID: AB_10003219,"},{"key":"2021121718173794800_CIT0027","volume-title":"RRID: AB_355192,"},{"key":"2021121718173794800_CIT0028","volume-title":"RRID: AB_640249,"},{"key":"2021121718173794800_CIT0029","volume-title":"RRID: AB_477163,"},{"key":"2021121718173794800_CIT0030","volume-title":"RRID: AB_10857217,"},{"key":"2021121718173794800_CIT0031","volume-title":"RRID: AB_2535792,"},{"issue":"16","key":"2021121718173794800_CIT0032","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.4161\/15384101.2014.943581","article-title":"Expression, regulation and function of Egr1 during implantation and decidualization in mice","volume":"13","author":"Guo","year":"2014","journal-title":"Cell Cycle."},{"issue":"43","key":"2021121718173794800_CIT0033","doi-asserted-by":"crossref","first-page":"31725","DOI":"10.1074\/jbc.M704723200","article-title":"Bone morphogenetic protein 2 functions via a conserved signaling pathway involving Wnt4 to regulate uterine decidualization in the mouse and the human","volume":"282","author":"Li","year":"2007","journal-title":"J Biol Chem."},{"issue":"4","key":"2021121718173794800_CIT0034","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1161\/HYPERTENSIONAHA.116.08468","article-title":"Testosterone represses estrogen signaling by upregulating miR-22: a mechanism for imbalanced steroid hormone production in preeclampsia","volume":"69","author":"Shao","year":"2017","journal-title":"Hypertension."},{"issue":"4","key":"2021121718173794800_CIT0035","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1210\/jcem-48-4-639","article-title":"Isolation and culture of human endometrial glands","volume":"48","author":"Satyaswaroop","year":"1979","journal-title":"J Clin Endocrinol Metab."},{"issue":"1","key":"2021121718173794800_CIT0036","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1620\/tjem.224.47","article-title":"Endometrial injury increases side population cells in the uterine endometrium: a decisive role of estrogen","volume":"224","author":"Hyodo","year":"2011","journal-title":"Tohoku J Exp Med."},{"issue":"3","key":"2021121718173794800_CIT0037","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/1744-7917.12552","article-title":"Genome-wide identification of chitin-binding proteins and characterization of BmCBP1 in the silkworm, Bombyx mori","volume":"26","author":"Li","year":"2019","journal-title":"Insect Sci."},{"issue":"8","key":"2021121718173794800_CIT0038","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/cr.2014.82","article-title":"Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms","volume":"24","author":"Zhang","year":"2014","journal-title":"Cell Res."},{"issue":"3","key":"2021121718173794800_CIT0039","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1210\/er.2003-0020","article-title":"Molecular cues to implantation","volume":"25","author":"Dey","year":"2004","journal-title":"Endocr Rev."},{"issue":"5","key":"2021121718173794800_CIT0040","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S1472-6483(10)60655-4","article-title":"Progesterone receptor requires a co-chaperone for signalling in uterine biology and implantation","volume":"13","author":"Tranguch","year":"2006","journal-title":"Reprod Biomed Online."},{"issue":"12","key":"2021121718173794800_CIT0041","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1093\/oxfordjournals.humrep.a138460","article-title":"Tumour necrosis factor alpha inhibits in-vitro decidualization of human endometrial stromal cells","volume":"9","author":"Inoue","year":"1994","journal-title":"Hum Reprod."},{"issue":"12","key":"2021121718173794800_CIT0042","doi-asserted-by":"crossref","first-page":"4270","DOI":"10.1210\/en.2017-00495","article-title":"IL-1\u03b2 inhibits connexin 43 and disrupts decidualization of human endometrial stromal cells through ERK1\/2 and p38 MAP kinase","volume":"158","author":"Yu","year":"2017","journal-title":"Endocrinology."},{"issue":"1","key":"2021121718173794800_CIT0043","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s40139-018-0161-2","article-title":"Tissue repair and epimorphic regeneration: an overview","volume":"6","author":"Londono","year":"2018","journal-title":"Curr Pathobiol Rep."},{"issue":"3","key":"2021121718173794800_CIT0044","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.ajog.2005.09.004","article-title":"The effect of dystocia and previous cesarean uterine scar on the tensile properties of the lower uterine segment","volume":"194","author":"Buhimschi","year":"2006","journal-title":"Am J Obstet Gynecol."},{"issue":"2","key":"2021121718173794800_CIT0045","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.tem.2019.11.008","article-title":"Uterine luminal epithelium as the transient gateway for embryo implantation","volume":"31","author":"Ye","year":"2020","journal-title":"Trends Endocrinol Metab."},{"issue":"3","key":"2021121718173794800_CIT0046","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nrg1808","article-title":"Roadmap to embryo implantation: clues from mouse models","volume":"7","author":"Wang","year":"2006","journal-title":"Nat Rev Genet."},{"issue":"12","key":"2021121718173794800_CIT0047","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1038\/nm.3012","article-title":"Mechanisms of implantation: strategies for successful pregnancy","volume":"18","author":"Cha","year":"2012","journal-title":"Nat Med."},{"issue":"1","key":"2021121718173794800_CIT0048","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1055\/s-0029-1242989","article-title":"Endometrial decidualization: of mice and men","volume":"28","author":"Ramathal","year":"2010","journal-title":"Semin Reprod Med."},{"issue":"Spec No 1","key":"2021121718173794800_CIT0049","first-page":"39","article-title":"Progesterone receptor requires a co-chaperone for signalling in uterine biology and implantation","volume":"14","author":"Tranguch","year":"2007","journal-title":"Reprod Biomed Online."},{"issue":"5","key":"2021121718173794800_CIT0050","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.mam.2012.12.011","article-title":"Physiological and molecular determinants of embryo implantation","volume":"34","author":"Zhang","year":"2013","journal-title":"Mol Aspects Med."},{"key":"2021121718173794800_CIT0051","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.ebiom.2018.11.015","article-title":"The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway","volume":"38","author":"Huang","year":"2018","journal-title":"EBioMedicine."},{"issue":"2","key":"2021121718173794800_CIT0052","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.repbio.2018.04.002","article-title":"Human amniotic epithelial cells inhibit activation and pro-inflammatory cytokines production of naive CD4+ T cells from women with unexplained recurrent spontaneous abortion","volume":"18","author":"Motedayyen","year":"2018","journal-title":"Reprod Biol."},{"issue":"1","key":"2021121718173794800_CIT0053","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s13287-017-0535-0","article-title":"Umbilical cord-derived mesenchymal stem cells on scaffolds facilitate collagen degradation via upregulation of MMP-9 in rat uterine scars","volume":"8","author":"Xu","year":"2017","journal-title":"Stem Cell Res Ther."},{"issue":"5","key":"2021121718173794800_CIT0054","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.mam.2012.07.017","article-title":"Navigating the site for embryo implantation: biomechanical and molecular regulation of intrauterine embryo distribution","volume":"34","author":"Chen","year":"2013","journal-title":"Mol Aspects Med."},{"key":"2021121718173794800_CIT0055","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1472-6483(10)60450-6","article-title":"Uterine dynamics: impact on the human reproduction process","volume":"18","author":"Fanchin","year":"2009","journal-title":"Reprod Biomed Online."},{"issue":"4","key":"2021121718173794800_CIT0056","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s10753-008-9067-1","article-title":"Hepatoprotective effect of infliximab, an anti-TNF-\u03b1 agent, on carbon tetrachloride-induced hepatic fibrosis","volume":"31","author":"Bahcecioglu","year":"2008","journal-title":"Inflammation."},{"issue":"5","key":"2021121718173794800_CIT0057","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1524-475X.2008.00410.x","article-title":"Growth factors and cytokines in wound healing","volume":"16","author":"Barrientos","year":"2008","journal-title":"Wound Repair Regen."},{"issue":"3","key":"2021121718173794800_CIT0058","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1136\/gut.2005.071118","article-title":"Tumour necrosis factor \u03b1 signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice","volume":"55","author":"Tomita","year":"2006","journal-title":"Gut."},{"issue":"7","key":"2021121718173794800_CIT0059","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/nm.2807","article-title":"Mechanisms of fibrosis: therapeutic translation for fibrotic disease","volume":"18","author":"Wynn","year":"2012","journal-title":"Nat Med."},{"issue":"3","key":"2021121718173794800_CIT0060","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1097\/GCO.0000000000000264","article-title":"Scratching and IVF: any role?","volume":"28","author":"Ko","year":"2016","journal-title":"Curr Opin Obstet Gynecol."},{"issue":"4","key":"2021121718173794800_CIT0061","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1056\/NEJMoa1808737","article-title":"A randomized trial of endometrial scratching before in vitro fertilization","volume":"380","author":"Lensen","year":"2019","journal-title":"N Engl J Med."},{"issue":"6","key":"2021121718173794800_CIT0062","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.fertnstert.2019.10.011","article-title":"In vitro fertilization add-ons for the endometrium: it doesn\u2019t add-up","volume":"112","author":"Lensen","year":"2019","journal-title":"Fertil Steril."},{"issue":"1","key":"2021121718173794800_CIT0063","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0002-9378(68)90428-6","article-title":"Placental site involution","volume":"102","author":"Anderson","year":"1968","journal-title":"Am J Obstet Gynecol."},{"issue":"6","key":"2021121718173794800_CIT0064","first-page":"715","article-title":"Classic pages in obstetrics and gynecology. Regeneration of the uterine mucosa after delivery, with special reference to the placental site: John Whitridge Williams, Americal Journal of Obstetrics and Gynecology, vol. 22, pp.664-696 and 793-796, 1931","volume":"134","author":"Longo","year":"1979","journal-title":"Am J Obstet Gynecol."},{"issue":"2","key":"2021121718173794800_CIT0065","first-page":"477","article-title":"Involution and regeneration of the endometrium following parturition in the ewe","volume":"236","author":"O\u2019Shea","year":"1984","journal-title":"Cell Tissue Res."},{"issue":"1","key":"2021121718173794800_CIT0066","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1530\/REP-09-0438","article-title":"Human uterine stem\/progenitor cells: their possible role in uterine physiology and pathology","volume":"140","author":"Maruyama","year":"2010","journal-title":"Reproduction."},{"issue":"1","key":"2021121718173794800_CIT0067","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/humupd\/dml045","article-title":"Uterine stem cells: what is the evidence?","volume":"13","author":"Gargett","year":"2007","journal-title":"Hum Reprod Update."},{"issue":"1","key":"2021121718173794800_CIT0068","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/00004347-199501000-00004","article-title":"Surgical pathology of the lower uterine segment caesarean section scar: is the scar a source of clinical symptoms?","volume":"14","author":"Morris","year":"1995","journal-title":"Int J Gynecol Pathol."},{"issue":"6","key":"2021121718173794800_CIT0069","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1093\/humupd\/7.6.567","article-title":"Clinical implications of postsurgical adhesions","volume":"7","author":"Diamond","year":"2001","journal-title":"Hum Reprod Update."}],"container-title":["Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/endo\/advance-article-pdf\/doi\/10.1210\/endocr\/bqaa174\/33793061\/bqaa174.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/endo\/article-pdf\/161\/11\/bqaa174\/41812455\/bqaa174.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/endo\/article-pdf\/161\/11\/bqaa174\/41812455\/bqaa174.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T19:43:40Z","timestamp":1639770220000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/endo\/article\/doi\/10.1210\/endocr\/bqaa174\/5911727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,25]]},"references-count":69,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11,1]]}},"URL":"https:\/\/doi.org\/10.1210\/endocr\/bqaa174","relation":{},"ISSN":["0013-7227","1945-7170"],"issn-type":[{"value":"0013-7227","type":"print"},{"value":"1945-7170","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,11]]},"published":{"date-parts":[[2020,9,25]]},"article-number":"bqaa174"}}