{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:00:39Z","timestamp":1779908439984,"version":"3.53.1"},"reference-count":76,"publisher":"The Endocrine Society","issue":"3","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82130046"],"award-info":[{"award-number":["82130046"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81571435"],"award-info":[{"award-number":["81571435"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31900598"],"award-info":[{"award-number":["31900598"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82101747"],"award-info":[{"award-number":["82101747"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Key Research and Development Program of China","award":["2022YFC2702701"],"award-info":[{"award-number":["2022YFC2702701"]}]},{"name":"National Key Research and Development Program of China","award":["2019YFA0802604"],"award-info":[{"award-number":["2019YFA0802604"]}]},{"name":"National Key Research and Development Program of China","award":["SHSMU-ZLCX20210201"],"award-info":[{"award-number":["SHSMU-ZLCX20210201"]}]},{"name":"National Key Research and Development Program of China","award":["SSMU-ZLCX20180401"],"award-info":[{"award-number":["SSMU-ZLCX20180401"]}]},{"DOI":"10.13039\/501100008750","name":"SHDC","doi-asserted-by":"crossref","award":["SHDC2020CR1046B"],"award-info":[{"award-number":["SHDC2020CR1046B"]}],"id":[{"id":"10.13039\/501100008750","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003395","name":"Shanghai Municipal Education Commission","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003395","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Gaofeng Clinical Medicine","award":["20161413"],"award-info":[{"award-number":["20161413"]}]},{"name":"Shanghai Jiaotong University School of Medicine"},{"DOI":"10.13039\/501100020737","name":"Renji Hospital","doi-asserted-by":"crossref","award":["RJPY-DZX-003"],"award-info":[{"award-number":["RJPY-DZX-003"]}],"id":[{"id":"10.13039\/501100020737","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Competent endometrial receptivity is a prerequisite for successful embryo implantation. Identification of novel key molecules involved in endometrial receptivity is essential to better interpret human implantation and improve pregnancy rates in assisted reproduction treatment. Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics was performed to profile the proteomes of the prereceptive (luteinizing hormone [LH] + 2, n = 4) and receptive (LH + 7, n = 4) endometrial tissues. A total of 173 differentially expressed proteins (DEPs) between LH + 2 and LH + 7 endometrial samples were identified. Integrated analysis of the proteomic data and published transcriptomic data was performed to identify the concordant DEPs with differential expression at both the messenger RNA and protein levels. Protein-protein interaction (PPI) network analysis was performed on concordant DEPs. We first identified 63 novel concordant DEPs and 5 hub proteins (ACSL4, ACSL5, COL1A1, PTGS1, and PLA2G4F) between LH + 2 and LH + 7 endometrial samples. ACSL4 was predominantly expressed in endometrial epithelial cells and its expression was significantly upregulated by progesterone in the LH + 7 endometrium and significantly downregulated in repeated implantation failure patients. Knockdown of ACSL4 in endometrial epithelial cells induced the downregulation of endometrial receptivity markers (HOXA10, COX2, and LIF) and the significant decrease of implantation rate during in vitro implantation analysis. This study provides the first gel-independent quantitative proteomes of the LH + 2 and LH + 7 human endometrium using iTRAQ technology. The identified concordant DEPs and hub proteins open a new avenue for future studies aimed at elucidating the underlying mechanisms governing endometrial receptivity. ACSL4 was identified as a novel regulatory molecule in the establishment of endometrial receptivity and might play important roles during implantation.<\/jats:p>","DOI":"10.1210\/endocr\/bqad012","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T18:10:50Z","timestamp":1674065450000},"source":"Crossref","is-referenced-by-count":9,"title":["iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity"],"prefix":"10.1210","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2896-0244","authenticated-orcid":false,"given":"Shuanggang","family":"Hu","sequence":"first","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Sun","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyu","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanting","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangxin","family":"Yao","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuejiao","family":"Bian","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tin Chiu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Chinese University of Hong Kong , Hong Kong 999077 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Vankelecom","sequence":"additional","affiliation":[{"name":"Department of Development and Regeneration, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, University of Leuven (KU Leuven) , B-3000 Leuven , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9073-8142","authenticated-orcid":false,"given":"Yun","family":"Sun","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2023,1,18]]},"reference":[{"issue":"12","key":"2023020208102742100_bqad012-B1","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1038\/nm.3012","article-title":"Mechanisms of implantation: strategies for successful pregnancy","volume":"18","author":"Cha","year":"2012","journal-title":"Nat Med"},{"issue":"6","key":"2023020208102742100_bqad012-B2","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/humupd\/dml004","article-title":"Endometrial receptivity markers, the journey to successful embryo implantation","volume":"12","author":"Achache","year":"2006","journal-title":"Hum Reprod Update"},{"issue":"3","key":"2023020208102742100_bqad012-B3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/GCO.0000000000000783","article-title":"Evaluation of endometrial receptivity and implantation failure","volume":"34","author":"Bui","year":"2022","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"1","key":"2023020208102742100_bqad012-B4","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/humrep\/17.1.213","article-title":"Concentration of leukaemia inhibitory factor (LIF) in uterine flushing fluid is highly predictive of embryo implantation","volume":"17","author":"L\u00e9d\u00e9e-Bataille","year":"2002","journal-title":"Hum Reprod"},{"key":"2023020208102742100_bqad012-B5","doi-asserted-by":"crossref","first-page":"103080","DOI":"10.1016\/j.jri.2020.103080","article-title":"The uterine immunological changes may be responsible for repeated implantation failure","volume":"138","author":"Amjadi","year":"2020","journal-title":"J Reprod Immunol"},{"issue":"3","key":"2023020208102742100_bqad012-B6","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.fertnstert.2011.07.1095","article-title":"Assessment of endometrial receptivity","volume":"96","author":"Lessey","year":"2011","journal-title":"Fertil Steril"},{"issue":"1","key":"2023020208102742100_bqad012-B7","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/humupd\/dmt048","article-title":"Guidelines for the design, analysis and interpretation of \u2018omics\u2019 data: focus on human endometrium","volume":"20","author":"Altm\u00e4e","year":"2014","journal-title":"Hum Reprod Update"},{"issue":"9","key":"2023020208102742100_bqad012-B8","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/molehr\/8.9.871","article-title":"Changes in gene expression during the early to mid-luteal (receptive phase) transition in human endometrium detected by high-density microarray screening","volume":"8","author":"Carson","year":"2002","journal-title":"Mol Hum Reprod"},{"issue":"1","key":"2023020208102742100_bqad012-B9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/molehr\/gag004","article-title":"Determination of the transcript profile of human endometrium","volume":"9","author":"Borthwick","year":"2003","journal-title":"Mol Hum Reprod"},{"issue":"6","key":"2023020208102742100_bqad012-B10","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1210\/endo.143.6.8885","article-title":"Global gene profiling in human endometrium during the window of implantation","volume":"143","author":"Kao","year":"2002","journal-title":"Endocrinology"},{"issue":"1","key":"2023020208102742100_bqad012-B11","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/humrep\/den360","article-title":"Identification of new biomarkers of human endometrial receptivity in the natural cycle","volume":"24","author":"Haouzi","year":"2009","journal-title":"Hum Reprod"},{"issue":"8","key":"2023020208102742100_bqad012-B12","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1093\/humrep\/dei051","article-title":"In search of candidate genes critically expressed in the human endometrium during the window of implantation","volume":"20","author":"Mirkin","year":"2005","journal-title":"Hum Reprod"},{"issue":"5","key":"2023020208102742100_bqad012-B13","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/molehr\/gag037","article-title":"Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology","volume":"9","author":"Riesewijk","year":"2003","journal-title":"Mol Hum Reprod"},{"issue":"3","key":"2023020208102742100_bqad012-B14","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1210\/en.2005-1076","article-title":"Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women","volume":"147","author":"Talbi","year":"2006","journal-title":"Endocrinology"},{"issue":"12","key":"2023020208102742100_bqad012-B15","doi-asserted-by":"crossref","first-page":"E2744","DOI":"10.1210\/jc.2014-2155","article-title":"Transcriptomic changes during the pre-receptive to receptive transition in human endometrium detected by RNA-Seq","volume":"99","author":"Hu","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2023020208102742100_bqad012-B16","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/pmic.200400920","article-title":"Proteomic analysis of the proliferative and secretory phases of the human endometrium: protein identification and differential protein expression","volume":"5","author":"DeSouza","year":"2005","journal-title":"Proteomics"},{"issue":"10","key":"2023020208102742100_bqad012-B17","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1093\/humrep\/dep230","article-title":"Proteomic analysis of the human receptive versus non-receptive endometrium using differential in-gel electrophoresis and MALDI-MS unveils stathmin 1 and annexin A2 as differentially regulated","volume":"24","author":"Dom\u00ednguez","year":"2009","journal-title":"Hum Reprod"},{"issue":"3","key":"2023020208102742100_bqad012-B18","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.fertnstert.2010.09.033","article-title":"Proteomic analysis of endometrium in fertile women during the prereceptive and receptive phases after luteinizing hormone surge","volume":"95","author":"Li","year":"2011","journal-title":"Fertil Steril"},{"issue":"1","key":"2023020208102742100_bqad012-B19","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/prca.200900094","article-title":"Proteome of human endometrium: identification of differentially expressed proteins in proliferative and secretory phase endometrium","volume":"4","author":"Rai","year":"2010","journal-title":"Proteomics Clin Appl"},{"issue":"3","key":"2023020208102742100_bqad012-B20","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.fertnstert.2008.07.1734","article-title":"Protein profiling of human endometrial tissues in the midsecretory and proliferative phases of the menstrual cycle","volume":"92","author":"Parmar","year":"2009","journal-title":"Fertil Steril"},{"issue":"4","key":"2023020208102742100_bqad012-B21","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1021\/acs.jproteome.5b00038","article-title":"Label-free proteomics uncovers energy metabolism and focal adhesion regulations responsive for endometrium receptivity","volume":"14","author":"Chen","year":"2015","journal-title":"J Proteome Res"},{"issue":"3","key":"2023020208102742100_bqad012-B22","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1080\/19336918.2015.1128623","article-title":"Human S100A10 plays a crucial role in the acquisition of the endometrial receptivity phenotype","volume":"10","author":"Bissonnette","year":"2016","journal-title":"Cell Adh Migr"},{"issue":"9","key":"2023020208102742100_bqad012-B23","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1093\/humrep\/deu171","article-title":"Deciphering the proteomic signature of human endometrial receptivity","volume":"29","author":"Garrido-G\u00f3mez","year":"2014","journal-title":"Hum Reprod"},{"issue":"11","key":"2023020208102742100_bqad012-B24","doi-asserted-by":"crossref","first-page":"e111687","DOI":"10.1371\/journal.pone.0111687","article-title":"Alteration in endometrial proteins during early- and mid-secretory phases of the cycle in women with unexplained infertility","volume":"9","author":"Manohar","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"2023020208102742100_bqad012-B25","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1021\/pr801024g","article-title":"Proteomic characterization of midproliferative and midsecretory human endometrium","volume":"8","author":"Chen","year":"2009","journal-title":"J Proteome Res"},{"key":"2023020208102742100_bqad012-B26","article-title":"Supplementary data for \u201ciTRAQ-based proteomic analysis unveils ACSL4 as a novel potential regulator of human endometrial receptivity.\u201d Figshare","author":"Hu"},{"issue":"9","key":"2023020208102742100_bqad012-B27","doi-asserted-by":"crossref","first-page":"e0137048","DOI":"10.1371\/journal.pone.0137048","article-title":"Comparative analysis of label-free and 8-plex iTRAQ approach for quantitative tissue proteomic analysis","volume":"10","author":"Latosinska","year":"2015","journal-title":"PLoS One"},{"issue":"7","key":"2023020208102742100_bqad012-B28","doi-asserted-by":"crossref","first-page":"3774","DOI":"10.1021\/pr300414z","article-title":"Comparison of 4-plex to 8-plex iTRAQ quantitative measurements of proteins in human plasma samples","volume":"11","author":"Pottiez","year":"2012","journal-title":"J Proteome Res"},{"issue":"7","key":"2023020208102742100_bqad012-B29","first-page":"717","article-title":"Proteomic analysis of eutopic and ectopic endometriotic tissues based on isobaric peptide tags for relative and absolute quantification (iTRAQ) method","volume":"34","author":"Marianowski","year":"2013","journal-title":"Neuro Endocrinol Lett"},{"issue":"20","key":"2023020208102742100_bqad012-B30","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1002\/pmic.201400145","article-title":"Effects of GnRH antagonist on endometrial protein profiles in the window of implantation","volume":"14","author":"Meng","year":"2014","journal-title":"Proteomics"},{"key":"2023020208102742100_bqad012-B31","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.3389\/fmicb.2017.01989","article-title":"iTRAQ proteomic analysis reveals that metabolic pathways involving energy metabolism are affected by tea tree oil in Botrytis cinerea","volume":"8","author":"Xu","year":"2017","journal-title":"Front Microbiol"},{"key":"2023020208102742100_bqad012-B32","doi-asserted-by":"crossref","first-page":"587448","DOI":"10.3389\/fphys.2020.587448","article-title":"A novel molecule in human cyclic endometrium: LncRNA TUNAR is involved in embryo implantation","volume":"11","author":"Wang","year":"2020","journal-title":"Front Physiol"},{"issue":"6","key":"2023020208102742100_bqad012-B33","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/cbf.3550","article-title":"CDC20 inhibitor apcin inhibits embryo implantation in vivo and in vitro","volume":"38","author":"Guo","year":"2020","journal-title":"Cell Biochem Funct"},{"issue":"1","key":"2023020208102742100_bqad012-B34","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1530\/JME-11-0094","article-title":"Effect of single post-ovulatory administration of levonorgestrel on gene expression profile during the receptive period of the human endometrium","volume":"48","author":"Vargas","year":"2012","journal-title":"J Mol Endocrinol"},{"issue":"1","key":"2023020208102742100_bqad012-B35","doi-asserted-by":"crossref","first-page":"e83612","DOI":"10.1371\/journal.pone.0083612","article-title":"Genome-wide DNA methylation profiling in cultured eutopic and ectopic endometrial stromal cells","volume":"9","author":"Yamagata","year":"2014","journal-title":"PLoS One"},{"key":"2023020208102742100_bqad012-B36","doi-asserted-by":"crossref","first-page":"785462","DOI":"10.3389\/fendo.2022.785462","article-title":"Integrated analysis of multiple microarrays based on raw data identified novel gene signatures in recurrent implantation failure","volume":"13","author":"Zeng","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"2023020208102742100_bqad012-B37","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1006\/bbrc.2001.5065","article-title":"Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency","volume":"284","author":"Cho","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"issue":"Suppl 2","key":"2023020208102742100_bqad012-B38","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/humrep\/14.suppl_2.17","article-title":"MUC-1 glycosylation in endometrium: possible roles of the apical glycocalyx at implantation","volume":"14","author":"Aplin","year":"1999","journal-title":"Hum Reprod"},{"issue":"12","key":"2023020208102742100_bqad012-B39","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/molehr\/4.12.1089","article-title":"MUC1 and endometrial receptivity","volume":"4","author":"Meseguer","year":"1998","journal-title":"Mol Hum Reprod"},{"key":"2023020208102742100_bqad012-B40","doi-asserted-by":"crossref","first-page":"702590","DOI":"10.3389\/fcell.2021.702590","article-title":"In situ synthesized monosodium urate crystal enhances endometrium decidualization via sterile inflammation during pregnancy","volume":"9","author":"Zhu","year":"2021","journal-title":"Front Cell Dev Biol"},{"issue":"3","key":"2023020208102742100_bqad012-B41","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1093\/molehr\/gaq094","article-title":"Comprehensive expression analysis of prostanoid enzymes and receptors in the human endometrium across the menstrual cycle","volume":"17","author":"Catalano","year":"2011","journal-title":"Mol Hum Reprod"},{"issue":"12","key":"2023020208102742100_bqad012-B42","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1172\/JCI13271","article-title":"Why there are two cyclooxygenase isozymes","volume":"107","author":"Smith","year":"2001","journal-title":"J Clin Invest"},{"issue":"4","key":"2023020208102742100_bqad012-B43","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1530\/REP-11-0438","article-title":"FKBP4 is regulated by HOXA10 during decidualization and in endometriosis","volume":"143","author":"Yang","year":"2012","journal-title":"Reproduction"},{"key":"2023020208102742100_bqad012-B44","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.biocel.2014.12.013","article-title":"The conceptus regulates tryptophanyl-tRNA synthetase and superoxide dismutase 2 in the sheep caruncular endometrium during early pregnancy","volume":"60","author":"Al-Gubory","year":"2015","journal-title":"Int J Biochem Cell Biol"},{"issue":"6","key":"2023020208102742100_bqad012-B45","doi-asserted-by":"crossref","first-page":"5075","DOI":"10.1007\/s11033-021-06502-x","article-title":"Endometrial gene expression profiling of recurrent implantation failure after in vitro fertilization","volume":"48","author":"Albayrak","year":"2021","journal-title":"Mol Biol Rep"},{"issue":"7","key":"2023020208102742100_bqad012-B46","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1177\/1933719118792104","article-title":"Potential marker pathways in the endometrium that may cause recurrent implantation failure","volume":"26","author":"Bastu","year":"2019","journal-title":"Reprod Sci"},{"issue":"6","key":"2023020208102742100_bqad012-B47","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1016\/j.fertnstert.2010.01.068","article-title":"The impact of luteal phase support on gene expression of extracellular matrix protein and adhesion molecules in the human endometrium during the window of implantation following controlled ovarian stimulation with a GnRH antagonist protocol","volume":"94","author":"Zhao","year":"2010","journal-title":"Fertil Steril"},{"issue":"1","key":"2023020208102742100_bqad012-B48","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1177\/1933719118756745","article-title":"Similar characteristics of endometrial and endometriotic epithelial cells","volume":"26","author":"Konrad","year":"2019","journal-title":"Reprod Sci"},{"issue":"11","key":"2023020208102742100_bqad012-B49","doi-asserted-by":"crossref","first-page":"E300","DOI":"10.1210\/jc.2010-0459","article-title":"Altered retinoid uptake and action contributes to cell survival in endometriosis","volume":"95","author":"Pavone","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"2023020208102742100_bqad012-B50","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1530\/REP-16-0592","article-title":"Altered retinoid signaling compromises decidualization in human endometriotic stromal cells","volume":"154","author":"Pavone","year":"2017","journal-title":"Reproduction"},{"issue":"3","key":"2023020208102742100_bqad012-B51","doi-asserted-by":"crossref","first-page":"e0173035","DOI":"10.1371\/journal.pone.0173035","article-title":"Reprogramming of the retinoic acid pathway in decidualizing human endometrial stromal cells","volume":"12","author":"Ozaki","year":"2017","journal-title":"PLoS One"},{"issue":"9","key":"2023020208102742100_bqad012-B52","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1177\/1933719118811643","article-title":"Impaired localization of claudin-11 in endometriotic epithelial cells compared to endometrial cells","volume":"26","author":"Horn\u00e9","year":"2019","journal-title":"Reprod Sci"},{"issue":"6","key":"2023020208102742100_bqad012-B53","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00418-015-1361-z","article-title":"Claudin-3, claudin-7, and claudin-10 show different distribution patterns during decidualization and trophoblast invasion in mouse and human","volume":"144","author":"Schumann","year":"2015","journal-title":"Histochem Cell Biol"},{"issue":"1","key":"2023020208102742100_bqad012-B54","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s43032-019-00041-4","article-title":"Expression of ALDH1A isozymes in human endometrium with and without endometriosis and in ovarian endometrioma","volume":"27","author":"Ma","year":"2020","journal-title":"Reprod Sci"},{"issue":"11","key":"2023020208102742100_bqad012-B55","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1002\/mrd.22112","article-title":"Gene profiling of inflammatory genes in day 18 endometria from pregnant and non-pregnant mares","volume":"79","author":"Patterson","year":"2012","journal-title":"Mol Reprod Dev"},{"issue":"11-12","key":"2023020208102742100_bqad012-B56","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1139\/o94-068","article-title":"Expression of tenascin during carcinogenesis and involution of hormone-dependent tissues","volume":"72","author":"Vollmer","year":"1994","journal-title":"Biochem Cell Biol"},{"issue":"4","key":"2023020208102742100_bqad012-B57","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/molehr\/4.4.407","article-title":"Progesterone receptor subtype B is differentially regulated in human endometrial stroma","volume":"4","author":"Wang","year":"1998","journal-title":"Mol Hum Reprod"},{"issue":"1","key":"2023020208102742100_bqad012-B58","doi-asserted-by":"crossref","first-page":"T1","DOI":"10.1530\/JME-19-0212","article-title":"90 Years of progesterone: new insights into progesterone receptor signaling in the endometrium required for embryo implantation","volume":"65","author":"DeMayo","year":"2020","journal-title":"J Mol Endocrinol"},{"issue":"2","key":"2023020208102742100_bqad012-B59","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1007\/s43032-020-00294-4","article-title":"Endometriosis cell proliferation induced by bone marrow mesenchymal stem cells","volume":"28","author":"Chen","year":"2021","journal-title":"Reprod Sci"},{"issue":"3","key":"2023020208102742100_bqad012-B60","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1095\/biolreprod.103.015933","article-title":"Expression pattern of metalloproteinases and tissue inhibitors of matrix-metalloproteinases in cycling human endometrium","volume":"69","author":"Goffin","year":"2003","journal-title":"Biol Reprod"},{"issue":"3","key":"2023020208102742100_bqad012-B61","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/abbs\/gmaa173","article-title":"Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis","volume":"53","author":"Wang","year":"2021","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"issue":"4","key":"2023020208102742100_bqad012-B62","doi-asserted-by":"crossref","first-page":"83","DOI":"10.14715\/cmb\/2019.65.4.14","article-title":"Nppc\/Npr2\/cGMP signaling cascade maintains oocyte developmental capacity","volume":"65","author":"Celik","year":"2019","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"issue":"474","key":"2023020208102742100_bqad012-B63","doi-asserted-by":"crossref","first-page":"eaaf7533","DOI":"10.1126\/scitranslmed.aaf7533","article-title":"Loss of HDAC3 results in nonreceptive endometrium and female infertility","volume":"11","author":"Kim","year":"2019","journal-title":"Sci Transl Med"},{"issue":"4","key":"2023020208102742100_bqad012-B64","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1095\/biolreprod.115.138115","article-title":"Epigenetic modulation of collagen 1A1: therapeutic implications in fibrosis and endometriosis","volume":"94","author":"Zheng","year":"2016","journal-title":"Biol Reprod"},{"issue":"6788","key":"2023020208102742100_bqad012-B65","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/35015694","article-title":"Protein function in the post-genomic era","volume":"405","author":"Eisenberg","year":"2000","journal-title":"Nature"},{"issue":"4","key":"2023020208102742100_bqad012-B66","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1194\/jlr.M013292","article-title":"Long-chain acyl-CoA synthetase 4 modulates prostaglandin E2 release from human arterial smooth muscle cells","volume":"52","author":"Golej","year":"2011","journal-title":"J Lipid Res"},{"issue":"11","key":"2023020208102742100_bqad012-B67","doi-asserted-by":"crossref","first-page":"e15540","DOI":"10.1371\/journal.pone.0015540","article-title":"Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells","volume":"5","author":"Maloberti","year":"2010","journal-title":"PLoS One"},{"issue":"9","key":"2023020208102742100_bqad012-B68","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.bbadis.2012.02.010","article-title":"Peroxisomal acyl-CoA synthetases","volume":"1822","author":"Watkins","year":"2012","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"2023020208102742100_bqad012-B69","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1677\/jme.1.01691","article-title":"An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and obligatory protein in the signal transduction pathway of steroidogenic hormones","volume":"34","author":"Cornejo Maciel","year":"2005","journal-title":"J Mol Endocrinol"},{"issue":"6","key":"2023020208102742100_bqad012-B70","doi-asserted-by":"crossref","first-page":"101912","DOI":"10.1016\/j.jogoh.2020.101912","article-title":"Anti-phospholipid antibody may reduce endometrial receptivity during the window of embryo implantation","volume":"50","author":"Tan","year":"2021","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"6521","key":"2023020208102742100_bqad012-B71","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/374460a0","article-title":"Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice","volume":"374","author":"Satokata","year":"1995","journal-title":"Nature"},{"issue":"3","key":"2023020208102742100_bqad012-B72","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1055\/s-2007-1016233","article-title":"Implantation in the baboon: endometrial responses","volume":"17","author":"Fazleabas","year":"1999","journal-title":"Semin Reprod Endocrinol"},{"issue":"5","key":"2023020208102742100_bqad012-B73","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1530\/rep.0.1260559","article-title":"Cyclooxygenase enzymes and prostaglandins in pathology of the endometrium","volume":"126","author":"Sales","year":"2003","journal-title":"Reproduction"},{"issue":"18","key":"2023020208102742100_bqad012-B74","doi-asserted-by":"crossref","first-page":"10082.","DOI":"10.3390\/ijms221810082","article-title":"Biomolecular markers of recurrent implantation failure\u2014a review","volume":"22","author":"Mrozikiewicz","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"4","key":"2023020208102742100_bqad012-B75","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.fertnstert.2009.07.1668","article-title":"Defective endometrial prostaglandin synthesis identified in patients with repeated implantation failure undergoing in vitro fertilization","volume":"94","author":"Achache","year":"2010","journal-title":"Fertil Steril"},{"issue":"1","key":"2023020208102742100_bqad012-B76","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.fertnstert.2004.06.057","article-title":"Distribution of cyclooxygenase-1, cyclooxygenase-2, and cytosolic phospholipase A2 in the luteal phase human endometrium and ovary","volume":"83","author":"Stavreus-Evers","year":"2005","journal-title":"Fertil Steril"}],"container-title":["Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/endo\/advance-article-pdf\/doi\/10.1210\/endocr\/bqad012\/48759217\/bqad012.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/endo\/article-pdf\/164\/3\/bqad012\/49042802\/bqad012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/endo\/article-pdf\/164\/3\/bqad012\/49042802\/bqad012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T08:11:56Z","timestamp":1675325516000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/endo\/article\/doi\/10.1210\/endocr\/bqad012\/6991315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,9]]},"references-count":76,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,1,9]]}},"URL":"https:\/\/doi.org\/10.1210\/endocr\/bqad012","relation":{},"ISSN":["1945-7170"],"issn-type":[{"value":"1945-7170","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3,1]]},"published":{"date-parts":[[2023,1,9]]},"article-number":"bqad012"}}