{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:17:02Z","timestamp":1792459022461,"version":"4.5.0"},"reference-count":384,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>An adrenal incidentaloma is now established as a common endocrine diagnosis that requires a multidisciplinary approach for effective management. The majority of patients can be reassured and discharged, but a personalized approach based upon image analysis, endocrine workup, and clinical symptoms and signs are required in every case. Adrenocortical carcinoma remains a real concern but is restricted to &amp;lt;2% of all cases. Functional adrenal incidentaloma lesions are commoner (but still probably &amp;lt;10% of total) and the greatest challenge remains the diagnosis and optimum management of autonomous cortisol secretion. Modern-day surgery has improved outcomes and novel radiological and urinary biomarkers will improve early detection and patient stratification in future years to come.<\/jats:p>","DOI":"10.1210\/endrev\/bnaa008","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T04:01:06Z","timestamp":1586318466000},"page":"775-820","source":"Crossref","is-referenced-by-count":322,"title":["Adrenal Incidentaloma"],"prefix":"10.1210","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4078-624X","authenticated-orcid":false,"given":"Mark","family":"Sherlock","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Beaumont Hospital, Dublin, Ireland"},{"name":"Royal College of Surgeons in Ireland, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Scarsbrook","sequence":"additional","affiliation":[{"name":"Department of Radiology, Leeds Teaching Hospitals NHS Trust, St James University Hospital, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2497-6887","authenticated-orcid":false,"given":"Afroze","family":"Abbas","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, St James University Hospital, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Fraser","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery, Leeds Teaching Hospitals NHS Trust, St James University Hospital, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padiporn","family":"Limumpornpetch","sequence":"additional","affiliation":[{"name":"Faculty of Medicine & Health, University of Leeds, Worsley Building, Clarendon Way, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9740-7621","authenticated-orcid":false,"given":"Rosemary","family":"Dineen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beaumont Hospital, Dublin, Ireland"},{"name":"Royal College of Surgeons in Ireland, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1749-9640","authenticated-orcid":false,"given":"Paul M","family":"Stewart","sequence":"additional","affiliation":[{"name":"Faculty of Medicine & Health, University of Leeds, Worsley Building, Clarendon Way, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2020,4,8]]},"reference":[{"issue":"10","key":"2021121110265556700_CIT0001","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1001\/jama.2018.1150","article-title":"Health care spending in the united states and other high-income countries","volume":"319","author":"Papanicolas","year":"2018","journal-title":"JAMA."},{"issue":"22","key":"2021121110265556700_CIT0002","doi-asserted-by":"crossref","first-page":"2400","DOI":"10.1001\/jama.2012.5960","article-title":"Use of diagnostic imaging studies and associated radiation exposure for patients enrolled in large integrated health care systems, 1996-2010","volume":"307","author":"Smith-Bindman","year":"2012","journal-title":"JAMA."},{"key":"2021121110265556700_CIT0003","volume-title":". 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