{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T16:41:07Z","timestamp":1787330467035,"version":"build-2736575974"},"reference-count":128,"publisher":"The Endocrine Society","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Obesity is a growing global health challenge associated with major cardiometabolic complications. While bariatric surgery remains the most effective treatment for severe obesity, recent advances in incretin-based pharmacotherapy, multireceptor agonists, and endoscopic bariatric procedures have substantially expanded therapeutic options. Beyond mechanical restriction, these interventions exert their effects through complex hormonal and neurophysiological mechanisms involving gut\u2013brain signaling, gastric motility, and enteroendocrine adaptations. Gut-derived hormones, including ghrelin, glucagon-like peptide-1 (GLP-1), peptide YY, amylin, and leptin, play a central role in the regulation of hunger, satiation, and satiety by integrating nutrient sensing, vagal afferent signaling, and central hypothalamic pathways. Surgical procedures, such as laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass, induce profound and durable hormonal remodeling, whereas endoscopic sleeve gastroplasty primarily modulates gastric physiology with more modest and heterogeneous endocrine effects. Intragastric balloons induce a transient delay in gastric emptying and achieve moderate short-term weight loss, although their metabolic and weight-loss effects appear limited in durability. In parallel, GLP-1 receptor agonists and emerging multiagonist therapies reproduce several postbariatric hormonal adaptations and achieve clinically meaningful weight loss. In this review, we summarize current knowledge on digestive hormone physiology and provide an updated overview of the hormonal mechanisms underlying pharmacologic, endoscopic, and surgical bariatric interventions, highlighting their respective roles within a continuum of obesity treatment strategies.<\/jats:p>","DOI":"10.1210\/endrev\/bnag032","type":"journal-article","created":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T11:33:49Z","timestamp":1786275229000},"source":"Crossref","is-referenced-by-count":0,"title":["Digestive hormones and their impact on bariatric and pharmacologic weight-loss therapies"],"prefix":"10.1210","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6682-2283","authenticated-orcid":false,"given":"Maxime","family":"Amoyel","sequence":"first","affiliation":[{"name":"Service d\u2019H\u00e9pato-gastro-ent\u00e9rologie, H\u00f4pital Bichat-Claude-Bernard, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 Paris Cit\u00e9 , Paris 75018 ,","place":["France"]},{"name":"Inserm Universit\u00e9 Paris Cit\u00e9 UMRS 1149 Centre de Recherche sur l\u2019Inflammation , Paris 75018 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8175-0369","authenticated-orcid":false,"given":"Claire","family":"Carette","sequence":"additional","affiliation":[{"name":"Inserm Universit\u00e9 Paris Cit\u00e9 UMRS 1149 Centre de Recherche sur l\u2019Inflammation , Paris 75018 ,","place":["France"]},{"name":"Service de Nutrition, H\u00f4pital Europ\u00e9en Georges Pompidou, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 Paris Cit\u00e9 , Paris 75015 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7103-1088","authenticated-orcid":false,"given":"Tigran","family":"Poghosyan","sequence":"additional","affiliation":[{"name":"Inserm Universit\u00e9 Paris Cit\u00e9 UMRS 1149 Centre de Recherche sur l\u2019Inflammation , Paris 75018 ,","place":["France"]},{"name":"Service de Chirurgie Digestive, \u0152sogastrique et Bariatrique, H\u00f4pital Bichat-Claude-Bernard, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 Paris Cit\u00e9 , Paris 75018 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanne","family":"Le Beyec-Le Bihan","sequence":"additional","affiliation":[{"name":"Inserm Universit\u00e9 Paris Cit\u00e9 UMRS 1149 Centre de Recherche sur l\u2019Inflammation , Paris 75018 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5372-4585","authenticated-orcid":false,"given":"Maude","family":"Le Gall","sequence":"additional","affiliation":[{"name":"Inserm Universit\u00e9 Paris Cit\u00e9 UMRS 1149 Centre de Recherche sur l\u2019Inflammation , Paris 75018 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"2026082112065600400_bnag032-B1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.metabol.2018.09.005","article-title":"The epidemiology of obesity","volume":"92","author":"Chooi","year":"2019","journal-title":"Metabolism"},{"key":"2026082112065600400_bnag032-B2","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2022.155217","article-title":"A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on","volume":"133","author":"Boutari","year":"2022","journal-title":"Metabolism"},{"issue":"1","key":"2026082112065600400_bnag032-B3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1001\/jama.2012.113905","article-title":"Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis","volume":"309","author":"Flegal","year":"2013","journal-title":"JAMA"},{"issue":"2","key":"2026082112065600400_bnag032-B4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1001\/jamasurg.2020.5666","article-title":"Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss and quality of life at 7 years in patients with morbid obesity: the SLEEVEPASS randomized clinical trial","volume":"156","author":"Gr\u00f6nroos","year":"2021","journal-title":"JAMA Surg"},{"issue":"8","key":"2026082112065600400_bnag032-B5","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1001\/jamasurg.2022.2229","article-title":"Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss, comorbidities, and reflux at 10 years in adult patients with obesity: the SLEEVEPASS randomized clinical trial","volume":"157","author":"Salminen","year":"2022","journal-title":"JAMA Surg"},{"issue":"3","key":"2026082112065600400_bnag032-B6","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/00000658-199509000-00011","article-title":"Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus","volume":"222","author":"Pories","year":"1995","journal-title":"Ann Surg"},{"issue":"8","key":"2026082112065600400_bnag032-B7","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1056\/NEJMoa066254","article-title":"Effects of bariatric surgery on mortality in Swedish obese subjects","volume":"357","author":"Sj\u00f6str\u00f6m","year":"2007","journal-title":"N Engl J Med"},{"issue":"8","key":"2026082112065600400_bnag032-B8","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1056\/NEJMoa066603","article-title":"Long-term mortality after gastric bypass surgery","volume":"357","author":"Adams","year":"2007","journal-title":"N Engl J Med"},{"issue":"17","key":"2026082112065600400_bnag032-B9","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1056\/NEJMoa1200225","article-title":"Bariatric surgery versus intensive medical therapy in obese patients with diabetes","volume":"366","author":"Schauer","year":"2012","journal-title":"N Engl J Med"},{"issue":"7","key":"2026082112065600400_bnag032-B10","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1381\/0960892054621242","article-title":"Laparoscopic sleeve gastrectomy as an initial bariatric operation for high-risk patients: initial results in 10 patients","volume":"15","author":"Mognol","year":"2005","journal-title":"Obes Surg"},{"issue":"2","key":"2026082112065600400_bnag032-B11","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/SLA.0b013e3181e90b31","article-title":"Long-term results of laparoscopic sleeve gastrectomy for obesity","volume":"252","author":"Himpens","year":"2010","journal-title":"Ann Surg"},{"issue":"3","key":"2026082112065600400_bnag032-B12","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1001\/jama.2017.20897","article-title":"Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity: the SM-BOSS randomized clinical trial","volume":"319","author":"Peterli","year":"2018","journal-title":"JAMA"},{"issue":"3","key":"2026082112065600400_bnag032-B13","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/jama.2017.20313","article-title":"Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the SLEEVEPASS randomized clinical trial","volume":"319","author":"Salminen","year":"2018","journal-title":"JAMA"},{"issue":"1","key":"2026082112065600400_bnag032-B14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1411892","article-title":"A randomized, controlled trial of 3.0\u2005mg of liraglutide in weight management","volume":"373","author":"Pi-Sunyer","year":"2015","journal-title":"N Engl J Med"},{"issue":"10278","key":"2026082112065600400_bnag032-B15","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0140-6736(21)00213-0","article-title":"Semaglutide 2\u00b74\u2005mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial","volume":"397","author":"Davies","year":"2021","journal-title":"Lancet"},{"issue":"1","key":"2026082112065600400_bnag032-B16","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1001\/jama.2023.24945","article-title":"Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: the SURMOUNT-4 randomized clinical trial","volume":"331","author":"Aronne","year":"2024","journal-title":"JAMA"},{"issue":"7","key":"2026082112065600400_bnag032-B17","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1056\/NEJMoa2502082","article-title":"Cagrilintide\u2013semaglutide in adults with overweight or obesity and type 2 diabetes","volume":"393","author":"Davies","year":"2025","journal-title":"N Engl J Med"},{"issue":"6","key":"2026082112065600400_bnag032-B18","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1056\/NEJMoa2301972","article-title":"Triple\u2013hormone-receptor agonist retatrutide for obesity\u2014a phase 2 trial","volume":"389","author":"Jastreboff","year":"2023","journal-title":"N Engl J Med"},{"issue":"10350","key":"2026082112065600400_bnag032-B19","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0140-6736(22)01280-6","article-title":"Endoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity (MERIT): a prospective, multicentre, randomised trial","volume":"400","author":"Abu Dayyeh","year":"2022","journal-title":"Lancet"},{"issue":"5","key":"2026082112065600400_bnag032-B20","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.cgh.2019.08.022","article-title":"Efficacy and safety of endoscopic sleeve gastroplasty: a systematic review and meta-analysis","volume":"18","author":"Hedjoudje","year":"2020","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"6","key":"2026082112065600400_bnag032-B21","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.gie.2020.10.016","article-title":"Endoscopic sleeve gastroplasty plus liraglutide versus endoscopic sleeve gastroplasty alone for weight loss","volume":"93","author":"Badurdeen","year":"2021","journal-title":"Gastrointest Endosc"},{"issue":"4","key":"2026082112065600400_bnag032-B22","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1381\/0960892053723411","article-title":"Effects of intragastric balloon on gastric emptying and plasma ghrelin levels in non-morbid obese patients","volume":"15","author":"Mion","year":"2005","journal-title":"Obes Surg"},{"issue":"5","key":"2026082112065600400_bnag032-B23","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1053\/j.gastro.2021.03.003","article-title":"AGA clinical practice guidelines on intragastric balloons in the management of obesity","volume":"160","author":"Muniraj","year":"2021","journal-title":"Gastroenterology"},{"issue":"7121","key":"2026082112065600400_bnag032-B24","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/nature05484","article-title":"Gut hormones and the regulation of energy homeostasis","volume":"444","author":"Murphy","year":"2006","journal-title":"Nature"},{"issue":"1","key":"2026082112065600400_bnag032-B25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1172\/JCI30227","article-title":"Gastrointestinal regulation of food intake","volume":"117","author":"Cummings","year":"2007","journal-title":"J Clin Invest"},{"issue":"8","key":"2026082112065600400_bnag032-B26","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.2337\/diabetes.50.8.1714","article-title":"A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans","volume":"50","author":"Cummings","year":"2001","journal-title":"Diabetes"},{"issue":"6762","key":"2026082112065600400_bnag032-B27","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/45230","article-title":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach","volume":"402","author":"Kojima","year":"1999","journal-title":"Nature"},{"issue":"6806","key":"2026082112065600400_bnag032-B28","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1038\/35038090","article-title":"Ghrelin induces adiposity in rodents","volume":"407","author":"Tsch\u00f6p","year":"2000","journal-title":"Nature"},{"issue":"12","key":"2026082112065600400_bnag032-B29","doi-asserted-by":"crossref","first-page":"3564","DOI":"10.1172\/JCI26002","article-title":"Mice lacking ghrelin receptors resist the development of diet-induced obesity","volume":"115","author":"Zigman","year":"2005","journal-title":"J Clin Invest"},{"issue":"5424","key":"2026082112065600400_bnag032-B30","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/245323a0","article-title":"Cholecystokinin elicits satiety in rats with open gastric fistulas","volume":"245","author":"Gibbs","year":"1973","journal-title":"Nature"},{"issue":"2","key":"2026082112065600400_bnag032-B31","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/ajcn\/34.2.154","article-title":"C-terminal octapeptide of cholecystokinin decreases food intake in man","volume":"34","author":"Kissileff","year":"1981","journal-title":"Am J Clin Nutr"},{"issue":"5910","key":"2026082112065600400_bnag032-B32","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/302703a0","article-title":"Rapid development of tolerance to the behavioural actions of cholecystokinin","volume":"302","author":"Crawley","year":"1983","journal-title":"Nature"},{"issue":"1","key":"2026082112065600400_bnag032-B33","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1749-6632.1985.tb29936.x","article-title":"The satiety effect of cholecystokinin recent progress and current problems","volume":"448","author":"Smith","year":"1985","journal-title":"Ann N Y Acad Sci"},{"key":"2026082112065600400_bnag032-B34","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2024.101945","article-title":"Stimulating intestinal GIP release reduces food intake and body weight in mice","volume":"84","author":"Lewis","year":"2024","journal-title":"Mol Metab"},{"key":"2026082112065600400_bnag032-B35","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/B978-0-12-571131-9.50017-7","volume-title":"Proceedings of the 1974 Laurentian Hormone Conference","author":"Brown","year":"1975"},{"issue":"2","key":"2026082112065600400_bnag032-B36","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1210\/jcem-39-2-223","article-title":"Gastric inhibitory polypeptide (GIP) stimulation by oral glucose in man","volume":"39","author":"Cataland","year":"1974","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"2026082112065600400_bnag032-B37","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0002-9610(75)90360-8","article-title":"Release of immunoreactive gastric inhibitory polypeptide (IR-GIP) by oral ingestion of food substances","volume":"130","author":"Cleator","year":"1975","journal-title":"Am J Surg"},{"issue":"2","key":"2026082112065600400_bnag032-B38","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1365-2362.1979.tb01678.x","article-title":"Impaired feedback control of fat induced gastric inhibitory polypeptide (GIP) secretion by insulin in obesity and glucose intolerance","volume":"9","author":"Ebert","year":"1979","journal-title":"Eur J Clin Invest"},{"issue":"6","key":"2026082112065600400_bnag032-B39","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1053\/j.gastro.2007.03.054","article-title":"Biology of incretins: GLP-1 and GIP","volume":"132","author":"Baggio","year":"2007","journal-title":"Gastroenterology"},{"issue":"5764","key":"2026082112065600400_bnag032-B40","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/285417a0","article-title":"Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides","volume":"285","author":"Tatemoto","year":"1980","journal-title":"Nature"},{"issue":"6898","key":"2026082112065600400_bnag032-B41","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/nature00887","article-title":"Gut hormone PYY3-36 physiologically inhibits food intake","volume":"418","author":"Batterham","year":"2002","journal-title":"Nature"},{"issue":"10","key":"2026082112065600400_bnag032-B42","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1056\/NEJMoa030204","article-title":"Inhibition of food intake in obese subjects by peptide YY3\u201336","volume":"349","author":"Batterham","year":"2003","journal-title":"N Engl J Med"},{"issue":"5910","key":"2026082112065600400_bnag032-B43","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1038\/302716a0","article-title":"Hamster preproglucagon contains the sequence of glucagon and two related peptides","volume":"302","author":"Bell","year":"1983","journal-title":"Nature"},{"issue":"2","key":"2026082112065600400_bnag032-B44","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1172\/JCI112855","article-title":"Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas","volume":"79","author":"Mojsov","year":"1987","journal-title":"J Clin Invest"},{"issue":"3","key":"2026082112065600400_bnag032-B45","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1172\/JCI990","article-title":"Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans","volume":"101","author":"Flint","year":"1998","journal-title":"J Clin Invest"},{"issue":"8","key":"2026082112065600400_bnag032-B46","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/BF00401145","article-title":"Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients","volume":"36","author":"Nauck","year":"1993","journal-title":"Diabetologia"},{"issue":"7","key":"2026082112065600400_bnag032-B47","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1210\/jc.2002-021545","article-title":"Synthetic exendin-4 (Exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes","volume":"88","author":"Kolterman","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"2026082112065600400_bnag032-B48","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/bph.15603","article-title":"Reappraising the role of the vagus nerve in GLP-1-mediated regulation of eating","volume":"179","author":"Brierley","year":"2022","journal-title":"Br J Pharmacol"},{"issue":"15","key":"2026082112065600400_bnag032-B49","doi-asserted-by":"crossref","first-page":"7911","DOI":"10.1073\/pnas.93.15.7911","article-title":"Induction of intestinal epithelial proliferation by glucagon-like peptide 2","volume":"93","author":"Drucker","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"2026082112065600400_bnag032-B50","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1073\/pnas.96.4.1569","article-title":"Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2","volume":"96","author":"Munroe","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"2026082112065600400_bnag032-B51","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1136\/gut.2010.218271","article-title":"Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and\/or intravenous fluid requirements in patients with short bowel syndrome","volume":"60","author":"Jeppesen","year":"2011","journal-title":"Gut"},{"issue":"3","key":"2026082112065600400_bnag032-B52","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1210\/jcem-57-3-488","article-title":"Molecular forms of human enteroglucagon in tissue and plasma: plasma responses to nutrient stimuli in health and in disorders of the upper gastrointestinal tract*","volume":"57","author":"Ghatei","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2026082112065600400_bnag032-B53","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/BF01119301","article-title":"Oxyntomodulin (glucagon-37 or bioactive enteroglucagon): a potent inhibitor of pentagastrin-stimulated acid secretion in rats","volume":"2","author":"Dubrasquet","year":"1982","journal-title":"Biosci Rep"},{"issue":"9","key":"2026082112065600400_bnag032-B54","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1007\/BF01538078","article-title":"Oxyntomodulin from distal gut: role in regulation of gastric and pancreatic functions","volume":"34","author":"Schjoldager","year":"1989","journal-title":"Dig Dis Sci"},{"issue":"6","key":"2026082112065600400_bnag032-B55","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1210\/en.2003-1338","article-title":"Peripheral oxyntomodulin reduces food intake and body weight gain in rats","volume":"145","author":"Dakin","year":"2004","journal-title":"Endocrinology"},{"issue":"24","key":"2026082112065600400_bnag032-B56","doi-asserted-by":"crossref","first-page":"9369","DOI":"10.1016\/S0021-9258(19)40653-4","article-title":"Isolation and characterization of a new pancreatic polypeptide hormone","volume":"250","author":"Kimmel","year":"1975","journal-title":"J Biol Chem"},{"issue":"8","key":"2026082112065600400_bnag032-B57","doi-asserted-by":"crossref","first-page":"3989","DOI":"10.1210\/jc.2003-030630","article-title":"Pancreatic polypeptide reduces appetite and food intake in humans","volume":"88","author":"Batterham","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"2026082112065600400_bnag032-B58","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.mce.2015.06.028","article-title":"The role of pancreatic polypeptide in the regulation of energy homeostasis","volume":"418 Pt 1","author":"Khandekar","year":"2015","journal-title":"Mol Cell Endocrinol"},{"issue":"3","key":"2026082112065600400_bnag032-B59","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0006-291X(86)90708-4","article-title":"A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas","volume":"140","author":"Westermark","year":"1986","journal-title":"Biochem Biophys Res Commun"},{"issue":"23","key":"2026082112065600400_bnag032-B60","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.23.8628","article-title":"Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients","volume":"84","author":"Cooper","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"2026082112065600400_bnag032-B61","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/BF00285291","article-title":"Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets","volume":"32","author":"Lukinius","year":"1989","journal-title":"Diabetologia"},{"issue":"8802","key":"2026082112065600400_bnag032-B62","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/0140-6736(92)90785-2","article-title":"Amylin concentrations and glucose control","volume":"339","author":"Koda","year":"1992","journal-title":"The Lancet"},{"issue":"2","key":"2026082112065600400_bnag032-B63","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/dmrr.263","article-title":"Role of amylin in insulin secretion and action in humans: antagonist studies across the spectrum of insulin sensitivity","volume":"18","author":"Mather","year":"2002","journal-title":"Diabetes Metab Res Rev"},{"key":"2026082112065600400_bnag032-B64","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s42255-026-01465-4","article-title":"The story of amylin: from physiology to therapy","volume":"8","author":"Secher","year":"2026","journal-title":"Nat Metab"},{"issue":"4","key":"2026082112065600400_bnag032-B65","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1753-4887.1987.tb07442.x","article-title":"Nutrition classics. The Journal of Laboratory and Clinical Medicine, Vol. VII, 1922: The internal secretion of the pancreas","volume":"45","author":"Banting","year":"2009","journal-title":"Nutr Rev"},{"issue":"5738","key":"2026082112065600400_bnag032-B66","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/282503a0","article-title":"Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons","volume":"282","author":"Woods","year":"1979","journal-title":"Nature"},{"issue":"5","key":"2026082112065600400_bnag032-B67","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1210\/endo-128-5-2645","article-title":"Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa\/Fa) but not obese (fa\/fa) zucker rats","volume":"128","author":"Schwartz","year":"1991","journal-title":"Endocrinology"},{"issue":"7121","key":"2026082112065600400_bnag032-B68","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nature05482","article-title":"Mechanisms linking obesity to insulin resistance and type 2 diabetes","volume":"444","author":"Kahn","year":"2006","journal-title":"Nature"},{"issue":"3","key":"2026082112065600400_bnag032-B69","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0031-9384(84)90160-4","article-title":"Effect of intracerebroventricularly infused glucagon on feeding behavior","volume":"33","author":"Inokuchi","year":"1984","journal-title":"Physiol Behav"},{"issue":"16","key":"2026082112065600400_bnag032-B70","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20163905","article-title":"Glucagon control on food intake and energy balance","volume":"20","author":"Al-Massadi","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"2","key":"2026082112065600400_bnag032-B71","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.neulet.2007.02.011","article-title":"Central administration of glucagon suppresses food intake in chicks","volume":"416","author":"Honda","year":"2007","journal-title":"Neurosci Lett"},{"issue":"8","key":"2026082112065600400_bnag032-B72","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1007\/s00125-023-05947-y","article-title":"100 years of glucagon and 100 more","volume":"66","author":"Wewer Albrechtsen","year":"2023","journal-title":"Diabetologia"},{"issue":"6695","key":"2026082112065600400_bnag032-B73","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/29547","article-title":"The stomach is a source of leptin","volume":"394","author":"Bado","year":"1998","journal-title":"Nature"},{"issue":"2","key":"2026082112065600400_bnag032-B74","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1136\/gut.47.2.178","article-title":"Leptin secretion and leptin receptor in the human stomach","volume":"47","author":"Sobhani","year":"2000","journal-title":"Gut"},{"issue":"6505","key":"2026082112065600400_bnag032-B75","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/372425a0","article-title":"Positional cloning of the mouse obese gene and its human homologue","volume":"372","author":"Zhang","year":"1994","journal-title":"Nature"},{"issue":"5223","key":"2026082112065600400_bnag032-B76","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1126\/science.7624778","article-title":"Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks","volume":"269","author":"Campfield","year":"1995","journal-title":"Science"},{"issue":"7","key":"2026082112065600400_bnag032-B77","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0092-8674(95)90151-5","article-title":"Identification and expression cloning of a leptin receptor, OB-R","volume":"83","author":"Tartaglia","year":"1995","journal-title":"Cell"},{"issue":"5","key":"2026082112065600400_bnag032-B78","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1056\/NEJM199602013340503","article-title":"Serum immunoreactive-leptin concentrations in normal-weight and obese humans","volume":"334","author":"Considine","year":"1996","journal-title":"N Engl J Med"},{"issue":"12","key":"2026082112065600400_bnag032-B79","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1038\/nm1295-1311","article-title":"Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action","volume":"1","author":"Frederich","year":"1995","journal-title":"Nat Med"},{"issue":"6704","key":"2026082112065600400_bnag032-B80","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/27376","article-title":"Leptin and the regulation of body weight in mammals","volume":"395","author":"Friedman","year":"1998","journal-title":"Nature"},{"issue":"6636","key":"2026082112065600400_bnag032-B81","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/43185","article-title":"Congenital leptin deficiency is associated with severe early-onset obesity in humans","volume":"387","author":"Montague","year":"1997","journal-title":"Nature"},{"issue":"2","key":"2026082112065600400_bnag032-B82","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/jmcb\/mjw011","article-title":"Adiponectin, the past two decades","volume":"8","author":"Wang","year":"2016","journal-title":"J Mol Cell Biol"},{"issue":"1","key":"2026082112065600400_bnag032-B83","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1146\/annurev-nutr-071816-064800","article-title":"Fibroblast growth factor 21: a versatile regulator of metabolic homeostasis","volume":"38","author":"BonDurant","year":"2018","journal-title":"Annu Rev Nutr"},{"issue":"25","key":"2026082112065600400_bnag032-B84","doi-asserted-by":"crossref","first-page":"15043","DOI":"10.1073\/pnas.95.25.15043","article-title":"The neuropeptide Y\/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice","volume":"95","author":"Broberger","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6778","key":"2026082112065600400_bnag032-B85","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/35007534","article-title":"Central nervous system control of food intake","volume":"404","author":"Schwartz","year":"2000","journal-title":"Nature"},{"issue":"7109","key":"2026082112065600400_bnag032-B86","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/nature05026","article-title":"Central nervous system control of food intake and body weight","volume":"443","author":"Morton","year":"2006","journal-title":"Nature"},{"issue":"1471","key":"2026082112065600400_bnag032-B87","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1098\/rstb.2006.1856","article-title":"Gastrointestinal hormones regulating appetite","volume":"361","author":"Chaudhri","year":"2006","journal-title":"Philos Trans R Soc B Biol Sci"},{"key":"2026082112065600400_bnag032-B88","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1002\/cphy.c200007","volume-title":"Comprehensive Physiology","author":"Schalla","year":"2021","edition":"1st ed"},{"issue":"10","key":"2026082112065600400_bnag032-B89","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqaf125","article-title":"Glucagon-like peptide 1 (GLP-1) action on hypothalamic feeding circuits","volume":"166","author":"Hwang","year":"2025","journal-title":"Endocrinology"},{"issue":"6","key":"2026082112065600400_bnag032-B90","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0896-6273(00)80656-X","article-title":"Leptin activates hypothalamic CART neurons projecting to the spinal cord","volume":"21","author":"Elias","year":"1998","journal-title":"Neuron"},{"issue":"3","key":"2026082112065600400_bnag032-B91","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1172\/JCI200522081","article-title":"Leptin action in the forebrain regulates the hindbrain response to satiety signals","volume":"115","author":"Morton","year":"2005","journal-title":"J Clin Invest"},{"issue":"1","key":"2026082112065600400_bnag032-B92","doi-asserted-by":"crossref","DOI":"10.1007\/s13679-026-00687-7","article-title":"Gut peptide alterations in type 2 diabetes and obesity: a narrative review","volume":"15","author":"Tzeravini","year":"2026","journal-title":"Curr Obes Rep"},{"issue":"1","key":"2026082112065600400_bnag032-B93","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s11684-013-0262-6","article-title":"Mechanisms of insulin resistance in obesity","volume":"7","author":"Ye","year":"2013","journal-title":"Front Med"},{"issue":"7","key":"2026082112065600400_bnag032-B94","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1001\/jama.2015.9676","article-title":"Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial","volume":"314","author":"Davies","year":"2015","journal-title":"JAMA"},{"issue":"22","key":"2026082112065600400_bnag032-B95","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1056\/NEJMoa1916038","article-title":"A randomized, controlled trial of liraglutide for adolescents with obesity","volume":"382","author":"Kelly","year":"2020","journal-title":"N Engl J Med"},{"issue":"11","key":"2026082112065600400_bnag032-B96","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1056\/NEJMoa2032183","article-title":"Once-weekly semaglutide in adults with overweight or obesity","volume":"384","author":"Wilding","year":"2021","journal-title":"N Engl J Med"},{"issue":"14","key":"2026082112065600400_bnag032-B97","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1001\/jama.2021.3224","article-title":"Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the STEP 4 randomized clinical trial","volume":"325","author":"Rubino","year":"2021","journal-title":"JAMA"},{"issue":"10","key":"2026082112065600400_bnag032-B98","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1038\/s41591-022-02026-4","article-title":"Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial","volume":"28","author":"Garvey","year":"2022","journal-title":"Nat Med"},{"issue":"24","key":"2026082112065600400_bnag032-B99","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1056\/NEJMoa2307563","article-title":"Semaglutide and cardiovascular outcomes in obesity without diabetes","volume":"389","author":"Lincoff","year":"2023","journal-title":"N Engl J Med"},{"issue":"1","key":"2026082112065600400_bnag032-B100","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/s41591-024-03355-2","article-title":"Proteomic changes upon treatment with semaglutide in individuals with obesity","volume":"31","author":"Maretty","year":"2025","journal-title":"Nat Med"},{"issue":"3","key":"2026082112065600400_bnag032-B101","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1056\/NEJMoa2206038","article-title":"Tirzepatide once weekly for the treatment of obesity","volume":"387","author":"Jastreboff","year":"2022","journal-title":"N Engl J Med"},{"issue":"10402","key":"2026082112065600400_bnag032-B102","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0140-6736(23)01200-X","article-title":"Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial","volume":"402","author":"Garvey","year":"2023","journal-title":"The Lancet"},{"issue":"11","key":"2026082112065600400_bnag032-B103","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1038\/s41591-023-02597-w","article-title":"Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial","volume":"29","author":"Wadden","year":"2023","journal-title":"Nat Med"},{"issue":"10403","key":"2026082112065600400_bnag032-B104","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/S0140-6736(23)01163-7","article-title":"Efficacy and safety of co-administered once-weekly cagrilintide 2\u00b74\u2005mg with once-weekly semaglutide 2\u00b74\u2005mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial","volume":"402","author":"Frias","year":"2023","journal-title":"Lancet"},{"key":"2026082112065600400_bnag032-B105","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1382814","article-title":"Semaglutide for weight loss: unanswered questions","volume":"15","author":"Tzoulis","year":"2024","journal-title":"Front Endocrinol"},{"issue":"9","key":"2026082112065600400_bnag032-B106","doi-asserted-by":"crossref","first-page":"5064","DOI":"10.1111\/dom.16554","article-title":"Weight reduction over time in tirzepatide-treated participants by early weight loss response: post hoc analysis in SURMOUNT-1","volume":"27","author":"Ard","year":"2025","journal-title":"Diabetes Obes Metab"},{"issue":"3","key":"2026082112065600400_bnag032-B107","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/SLA.0b013e318156f012","article-title":"Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study","volume":"247","author":"Karamanakos","year":"2008","journal-title":"Ann Surg"},{"issue":"6","key":"2026082112065600400_bnag032-B108","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1007\/s11695-016-2505-5","article-title":"Changes in fasting and prandial gut and adiposity hormones following vertical sleeve gastrectomy or Roux-en-Y-gastric bypass: an 18-month prospective study","volume":"27","author":"Alamuddin","year":"2017","journal-title":"Obes Surg"},{"key":"2026082112065600400_bnag032-B109","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.clnu.2025.09.014","article-title":"Meal-induced PYY and GLP1 secretions differently predict long-term weight loss after sleeve gastrectomy","volume":"54","author":"Janot","year":"2025","journal-title":"Clin Nutr"},{"issue":"1","key":"2026082112065600400_bnag032-B110","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/SLA.0000000000003614","article-title":"Effect of sleeve gastrectomy on ghrelin, GLP-1, PYY, and GIP gut hormones: a systematic review and meta-analysis","volume":"272","author":"McCarty","year":"2020","journal-title":"Ann Surg"},{"issue":"12","key":"2026082112065600400_bnag032-B111","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1007\/s11695-017-2779-2","article-title":"Metabolic effects of sleeve gastrectomy and laparoscopic greater curvature plication: an 18-month prospective, observational, open-label study","volume":"27","author":"Bu\u017ega","year":"2017","journal-title":"Obes Surg"},{"issue":"21","key":"2026082112065600400_bnag032-B112","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1056\/NEJMoa012908","article-title":"Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery","volume":"346","author":"Cummings","year":"2002","journal-title":"N Engl J Med"},{"issue":"7","key":"2026082112065600400_bnag032-B113","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/ijo.2009.79","article-title":"Prospective study of gut hormone and metabolic changes after adjustable gastric banding and Roux-en-Y gastric bypass","volume":"33","author":"Korner","year":"2009","journal-title":"Int J Obes"},{"issue":"4","key":"2026082112065600400_bnag032-B114","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1007\/s11695-018-03686-3","article-title":"Systematic review and meta-analysis of the change in ghrelin levels after Roux-en-Y gastric bypass","volume":"29","author":"Xu","year":"2019","journal-title":"Obes Surg"},{"issue":"5","key":"2026082112065600400_bnag032-B115","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13702","article-title":"Gut peptides before and following Roux-En-Y gastric bypass: a systematic review and meta-analysis","volume":"25","author":"Simoneau","year":"2024","journal-title":"Obes Rev"},{"issue":"3","key":"2026082112065600400_bnag032-B116","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s11695-017-2913-1","article-title":"A meta-analysis of GLP-1 after Roux-En-Y gastric bypass: impact of surgical technique and measurement strategy","volume":"28","author":"Jirapinyo","year":"2018","journal-title":"Obes Surg"},{"issue":"2","key":"2026082112065600400_bnag032-B117","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1053\/j.gastro.2015.10.009","article-title":"Differences in alimentary glucose absorption and intestinal disposal of blood glucose after Roux-en-Y gastric bypass vs sleeve gastrectomy","volume":"150","author":"Cavin","year":"2016","journal-title":"Gastroenterology"},{"issue":"1","key":"2026082112065600400_bnag032-B118","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.soard.2022.08.020","article-title":"Mucosal and hormonal adaptations after Roux-en-Y gastric bypass","volume":"19","author":"Feris","year":"2023","journal-title":"Surg Obes Relat Dis"},{"issue":"12","key":"2026082112065600400_bnag032-B119","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.2337\/dc12-0197","article-title":"Alterations in gastrointestinal, endocrine, and metabolic processes after bariatric Roux-en-Y gastric bypass surgery","volume":"35","author":"Anderwald","year":"2012","journal-title":"Diabetes Care"},{"issue":"2","key":"2026082112065600400_bnag032-B120","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s11695-016-2296-8","article-title":"Efficacy of first-time intragastric balloon in weight loss: a systematic review and meta-analysis of randomized controlled trials","volume":"27","author":"Saber","year":"2017","journal-title":"Obes Surg"},{"issue":"7","key":"2026082112065600400_bnag032-B121","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1007\/s11695-020-04558-5","article-title":"Efficacy of intragastric balloons for weight loss in overweight and obese adults: a systematic review and meta-analysis of randomized controlled trials","volume":"30","author":"Kotinda","year":"2020","journal-title":"Obes Surg"},{"issue":"5","key":"2026082112065600400_bnag032-B122","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s11695-012-0834-6","article-title":"Fasting and meal-induced CCK and PP secretion following intragastric balloon treatment for obesity","volume":"23","author":"Mathus-Vliegen","year":"2013","journal-title":"Obes Surg"},{"issue":"5","key":"2026082112065600400_bnag032-B123","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1210\/jc.2008-1083","article-title":"The effect of intragastric balloon on plasma ghrelin, leptin, and adiponectin levels in patients with morbid obesity","volume":"94","author":"Konopko-Zubrzycka","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2026082112065600400_bnag032-B124","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s11695-013-1053-5","article-title":"Fasting and meal-suppressed ghrelin levels before and after intragastric balloons and balloon-induced weight loss","volume":"24","author":"Mathus-Vliegen","year":"2014","journal-title":"Obes Surg"},{"issue":"6","key":"2026082112065600400_bnag032-B125","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1007\/s11695-025-07907-4","article-title":"Comparative analysis of laparoscopic sleeve gastrectomy with and without prior endoscopic intragastric balloon insertion: examining stomach volumetry, histopathologic changes, hormonal levels, and postoperative outcomes","volume":"35","author":"Hany","year":"2025","journal-title":"Obes Surg"},{"issue":"1","key":"2026082112065600400_bnag032-B126","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cgh.2015.12.030","article-title":"Endoscopic sleeve gastroplasty alters gastric physiology and induces loss of body weight in obese individuals","volume":"15","author":"Abu Dayyeh","year":"2017","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"7","key":"2026082112065600400_bnag032-B127","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1007\/s11695-020-04541-0","article-title":"Gut and metabolic hormones changes after endoscopic sleeve gastroplasty (ESG) vs. laparoscopic sleeve gastrectomy (LSG)","volume":"30","author":"Lopez-Nava","year":"2020","journal-title":"Obes Surg"},{"issue":"17","key":"2026082112065600400_bnag032-B128","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJMoa1105816","article-title":"Long-term persistence of hormonal adaptations to weight loss","volume":"365","author":"Sumithran","year":"2011","journal-title":"N Engl J Med"}],"container-title":["Endocrine Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/edrv\/advance-article-pdf\/doi\/10.1210\/endrev\/bnag032\/70617669\/bnag032.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/edrv\/advance-article-pdf\/doi\/10.1210\/endrev\/bnag032\/70617669\/bnag032.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T16:07:19Z","timestamp":1787328439000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/edrv\/advance-article\/doi\/10.1210\/endrev\/bnag032\/8759529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,12]]},"references-count":128,"URL":"https:\/\/doi.org\/10.1210\/endrev\/bnag032","relation":{},"ISSN":["0163-769X","1945-7189"],"issn-type":[{"value":"0163-769X","type":"print"},{"value":"1945-7189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,12]]},"article-number":"bnag032"}}