{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T11:40:03Z","timestamp":1792669203838,"version":"4.5.0"},"reference-count":823,"publisher":"The Endocrine Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Two major functions of the mammalian ovary are the production of germ cells (oocytes), which allow continuation of the species, and the generation of bioactive molecules, primarily steroids (mainly estrogens and progestins) and peptide growth factors, which are critical for ovarian function, regulation of the hypothalamic-pituitary-ovarian axis, and development of secondary sex characteristics. The female germline is created during embryogenesis when the precursors of primordial germ cells differentiate from somatic lineages of the embryo and take a unique route to reach the urogenital ridge. This undifferentiated gonad will differentiate along a female pathway, and the newly formed oocytes will proliferate and subsequently enter meiosis. At this point, the oocyte has two alternative fates: die, a common destiny of millions of oocytes, or be fertilized, a fate of at most approximately 100 oocytes, depending on the species. At every step from germline development and ovary formation to oogenesis and ovarian development and differentiation, there are coordinated interactions of hundreds of proteins and small RNAs. These studies have helped reproductive biologists to understand not only the normal functioning of the ovary but also the pathophysiology and genetics of diseases such as infertility and ovarian cancer. Over the last two decades, parallel progress has been made in the assisted reproductive technology clinic including better hormonal preparations, prenatal genetic testing, and optimal oocyte and embryo analysis and cryopreservation. Clearly, we have learned much about the mammalian ovary and manipulating its most important cargo, the oocyte, since the birth of Louise Brown over 30 yr ago.<\/jats:p>","DOI":"10.1210\/er.2009-0012","type":"journal-article","created":{"date-parts":[[2009,10,12]],"date-time":"2009-10-12T18:09:52Z","timestamp":1255370992000},"page":"624-712","source":"Crossref","is-referenced-by-count":729,"title":["The Mammalian Ovary from Genesis to Revelation"],"prefix":"10.1210","volume":"30","author":[{"given":"Mark A.","family":"Edson","sequence":"first","affiliation":[{"name":"Departments of Pathology (M.A.E., A.K.N., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"},{"name":"Molecular and Cellular Biology (M.A.E., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur K.","family":"Nagaraja","sequence":"first","affiliation":[{"name":"Departments of Pathology (M.A.E., A.K.N., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"},{"name":"Molecular and Human Genetics (A.K.N., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin M.","family":"Matzuk","sequence":"first","affiliation":[{"name":"Departments of Pathology (M.A.E., A.K.N., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"},{"name":"Molecular and Cellular Biology (M.A.E., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"},{"name":"Molecular and Human Genetics (A.K.N., M.M.M.), Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"2020071611592878700_R1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/ar.1091180202","article-title":"The identification, origin and migration of the primordial germ cells in the mouse embryo.","volume":"118","author":"Chiquoine","year":"1954","journal-title":"Anat Rec"},{"key":"2020071611592878700_R2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/jez.1401340202","article-title":"Gene-induced embryological modifications of primordial germ cells in the mouse.","volume":"134","author":"Mintz","year":"1957","journal-title":"J Exp Zool"},{"key":"2020071611592878700_R3","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/BF01932475","article-title":"A study of the primordial germ cells during their migratory phase in Steel mutant mice.","volume":"31","author":"McCoshen","year":"1975","journal-title":"Experientia"},{"key":"2020071611592878700_R4","first-page":"367","article-title":"Observations on the origin of the primordial germ cells in the mouse.","volume":"17","author":"Ozdzenski","year":"1967","journal-title":"Zool Polon"},{"key":"2020071611592878700_R5","first-page":"97","article-title":"A light- and electron-microscopic study of primordial germ cells in the early mouse embryo.","volume":"30","author":"Spiegelman","year":"1973","journal-title":"J Embryol Exp Morphol"},{"key":"2020071611592878700_R6","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/0012-1606(75)90269-9","article-title":"Fine structural observations on the origin and associations of primordial germ cells of the mouse.","volume":"47","author":"Clark","year":"1975","journal-title":"Dev Biol"},{"key":"2020071611592878700_R7","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1242\/dev.110.2.521","article-title":"Primordial germ cells in the mouse embryo during gastrulation.","volume":"110","author":"Ginsburg","year":"1990","journal-title":"Development"},{"key":"2020071611592878700_R8","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1242\/dev.121.5.1487","article-title":"Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells.","volume":"121","author":"MacGregor","year":"1995","journal-title":"Development"},{"key":"2020071611592878700_R9","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1210\/er.2002-0003","article-title":"Genetic analysis of the mammalian TGF-\u03b2 superfamily.","volume":"23","author":"Chang","year":"2002","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R10","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1126\/science.1137545","article-title":"Germ cell specification in mice.","volume":"316","author":"Hayashi","year":"2007","journal-title":"Science"},{"key":"2020071611592878700_R11","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.gde.2008.06.003","article-title":"Mouse germ cell development during embryogenesis.","volume":"18","author":"Saga","year":"2008","journal-title":"Curr Opin Genet Dev"},{"key":"2020071611592878700_R12","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1101\/gad.13.4.424","article-title":"Bmp4 is required for the generation of primordial germ cells in the mouse embryo.","volume":"13","author":"Lawson","year":"1999","journal-title":"Genes Dev"},{"key":"2020071611592878700_R13","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1210\/mend.14.7.0479","article-title":"Requirement of BMP8b for the generation of primordial germ cells in the mouse.","volume":"14","author":"Ying","year":"2000","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R14","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1006\/dbio.2001.0173","article-title":"Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.","volume":"232","author":"Ying","year":"2001","journal-title":"Dev Biol"},{"key":"2020071611592878700_R15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0925-4773(01)00367-7","article-title":"Smad5 is required for mouse primordial germ cell development.","volume":"104","author":"Chang","year":"2001","journal-title":"Mech Dev"},{"key":"2020071611592878700_R16","doi-asserted-by":"crossref","first-page":"3609","DOI":"10.1242\/dev.128.18.3609","article-title":"Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation.","volume":"128","author":"Tremblay","year":"2001","journal-title":"Development"},{"key":"2020071611592878700_R17","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0925-4773(02)00237-X","article-title":"SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast.","volume":"118","author":"Hayashi","year":"2002","journal-title":"Mech Dev"},{"key":"2020071611592878700_R18","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1242\/dev.01248","article-title":"Differential requirements for Smad4 in TGF\u03b2-dependent patterning of the early mouse embryo.","volume":"131","author":"Chu","year":"2004","journal-title":"Development"},{"key":"2020071611592878700_R19","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ydbio.2006.04.442","article-title":"Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.","volume":"296","author":"Arnold","year":"2006","journal-title":"Dev Biol"},{"key":"2020071611592878700_R20","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/1471-213X-7-140","article-title":"Proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors.","volume":"7","author":"Lopes","year":"2007","journal-title":"BMC Dev Biol"},{"key":"2020071611592878700_R21","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/nature00927","article-title":"A molecular programme for the specification of germ cell fate in mice.","volume":"418","author":"Saitou","year":"2002","journal-title":"Nature"},{"key":"2020071611592878700_R22","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1128\/MCB.02064-07","article-title":"Degradation of a polyadenylated rRNA maturation by-product involves one of the three RRP6-like proteins in Arabidopsis thaliana.","volume":"28","author":"Lange","year":"2008","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R23","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nature03813","article-title":"Blimp1 is a critical determinant of the germ cell lineage in mice.","volume":"436","author":"Ohinata","year":"2005","journal-title":"Nature"},{"key":"2020071611592878700_R24","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1016\/j.cub.2003.11.026","article-title":"Stella is a maternal effect gene required for normal early development in mice.","volume":"13","author":"Payer","year":"2003","journal-title":"Curr Biol"},{"key":"2020071611592878700_R25","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-213X-4-2","article-title":"Dppa3\/Pgc7\/stella is a maternal factor and is not required for germ cell specification in mice.","volume":"4","author":"Bortvin","year":"2004","journal-title":"BMC Dev Biol"},{"key":"2020071611592878700_R26","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1242\/dev.01711","article-title":"The zinc finger transcriptional repressor Blimp1\/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse.","volume":"132","author":"Vincent","year":"2005","journal-title":"Development"},{"key":"2020071611592878700_R27","doi-asserted-by":"crossref","first-page":"4335","DOI":"10.1242\/dev.012047","article-title":"Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice.","volume":"134","author":"Robertson","year":"2007","journal-title":"Development"},{"key":"2020071611592878700_R28","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1095\/biolreprod.106.053686","article-title":"Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling.","volume":"75","author":"Yabuta","year":"2006","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R29","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1038\/ng.186","article-title":"Critical function of Prdm14 for the establishment of the germ cell lineage in mice.","volume":"40","author":"Yamaji","year":"2008","journal-title":"Nat Genet"},{"key":"2020071611592878700_R30","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/nature08210","article-title":"A role for Lin28 in primordial germ-cell development and germ-cell malignancy.","volume":"460","author":"West","year":"2009","journal-title":"Nature"},{"key":"2020071611592878700_R31","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.molcel.2008.09.014","article-title":"Lin28 mediates the terminal uridylation of let-7 precursor microRNA.","volume":"32","author":"Heo","year":"2008","journal-title":"Mol Cell"},{"key":"2020071611592878700_R32","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1261\/rna.1155108","article-title":"Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing.","volume":"14","author":"Newman","year":"2008","journal-title":"RNA"},{"key":"2020071611592878700_R33","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/ncb1759","article-title":"A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.","volume":"10","author":"Rybak","year":"2008","journal-title":"Nat Cell Biol"},{"key":"2020071611592878700_R34","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1126\/science.1154040","article-title":"Selective blockade of microRNA processing by Lin28.","volume":"320","author":"Viswanathan","year":"2008","journal-title":"Science"},{"key":"2020071611592878700_R35","doi-asserted-by":"crossref","first-page":"21310","DOI":"10.1074\/jbc.C800108200","article-title":"Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.","volume":"283","author":"Piskounova","year":"2008","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R36","doi-asserted-by":"crossref","first-page":"9649","DOI":"10.1158\/0008-5472.CAN-06-4111","article-title":"Gene amplification and overexpression of PRDM14 in breast cancers.","volume":"67","author":"Nishikawa","year":"2007","journal-title":"Cancer Res"},{"key":"2020071611592878700_R37","doi-asserted-by":"crossref","first-page":"e3823","DOI":"10.1371\/journal.pone.0003823","article-title":"The zinc finger SET domain gene Prdm14 is overexpressed in lymphoblastic lymphomas with retroviral insertions at Evi32","volume":"3","author":"Dettman","year":"2008","journal-title":"PLoS ONE"},{"key":"2020071611592878700_R38","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.bbrc.2007.12.189","article-title":"PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells.","volume":"367","author":"Tsuneyoshi","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"2020071611592878700_R39","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/ni1046","article-title":"PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing.","volume":"5","author":"Gyory","year":"2004","journal-title":"Nat Immunol"},{"key":"2020071611592878700_R40","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1242\/dev.005611","article-title":"Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice.","volume":"134","author":"Seki","year":"2007","journal-title":"Development"},{"key":"2020071611592878700_R41","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1038\/nature06714","article-title":"Chromatin dynamics during epigenetic reprogramming in the mouse germ line.","volume":"452","author":"Hajkova","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R42","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ydbio.2005.05.019","article-title":"Altered primordial germ cell migration in the absence of transforming growth factor \u03b2 signaling via ALK5.","volume":"284","author":"Chuva de Sousa Lopes","year":"2005","journal-title":"Dev Biol"},{"key":"2020071611592878700_R43","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ydbio.2007.03.031","article-title":"Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells.","volume":"306","author":"Farini","year":"2007","journal-title":"Dev Biol"},{"key":"2020071611592878700_R44","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1126\/science.1085222","article-title":"Conserved role of nanos proteins in germ cell development.","volume":"301","author":"Tsuda","year":"2003","journal-title":"Science"},{"key":"2020071611592878700_R45","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/nature03595","article-title":"The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.","volume":"435","author":"Youngren","year":"2005","journal-title":"Nature"},{"key":"2020071611592878700_R46","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/ncb1413","article-title":"Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.","volume":"8","author":"Ancelin","year":"2006","journal-title":"Nat Cell Biol"},{"key":"2020071611592878700_R47","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1371\/journal.pgen.0040030","article-title":"A X chromosome activity in mouse XX primordial germ cells","volume":"4","author":"Chuva de Sousa Lopes","year":"2008","journal-title":"PLoS Genet"},{"key":"2020071611592878700_R48","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1242\/dev.124.9.1653","article-title":"Defects of urogenital development in mice lacking Emx2.","volume":"124","author":"Miyamoto","year":"1997","journal-title":"Development"},{"key":"2020071611592878700_R49","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/ng1297-467","article-title":"Donor splice-site mutations in WT1 are responsible for Frasier syndrome.","volume":"17","author":"Barbaux","year":"1997","journal-title":"Nat Genet"},{"key":"2020071611592878700_R50","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1002\/ajmg.a.31997","article-title":"Complete sex reversal in a WAGR syndrome patient","volume":"143A","author":"Le Caignec","year":"2007","journal-title":"Am J Med Genet A"},{"key":"2020071611592878700_R51","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0092-8674(93)90515-R","article-title":"WT-1 is required for early kidney development.","volume":"74","author":"Kreidberg","year":"1993","journal-title":"Cell"},{"key":"2020071611592878700_R52","doi-asserted-by":"crossref","first-page":"11932","DOI":"10.1073\/pnas.97.22.11932","article-title":"Molecular basis for modulation of biological function by alternate splicing of the Wilms\u2019 tumor suppressor protein.","volume":"97","author":"Laity","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R53","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0092-8674(01)00453-6","article-title":"Two splice variants of the Wilms\u2019 tumor 1 gene have distinct functions during sex determination and nephron formation.","volume":"106","author":"Hammes","year":"2001","journal-title":"Cell"},{"key":"2020071611592878700_R54","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1101\/gad.220102","article-title":"The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1.","volume":"16","author":"Wilhelm","year":"2002","journal-title":"Genes Dev"},{"key":"2020071611592878700_R55","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1471-2199-9-44","article-title":"A GATA4\/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation.","volume":"9","author":"Miyamoto","year":"2008","journal-title":"BMC Mol Biol"},{"key":"2020071611592878700_R56","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/35002622","article-title":"The LIM homeobox gene Lhx9 is essential for mouse gonad formation.","volume":"403","author":"Birk","year":"2000","journal-title":"Nature"},{"key":"2020071611592878700_R57","first-page":"271","article-title":"Recherches sur la differenciation sexuelle de l\u2019 embryon de lapin.","volume":"36","author":"Jost","year":"1947","journal-title":"Arch Anat Microsci Morphol Exp"},{"key":"2020071611592878700_R58","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1471-213X-8-67","article-title":"GATA4\/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development.","volume":"8","author":"Smagulova","year":"2008","journal-title":"BMC Dev Biol"},{"key":"2020071611592878700_R59","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/0092-8674(94)90211-9","article-title":"A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.","volume":"77","author":"Luo","year":"1994","journal-title":"Cell"},{"key":"2020071611592878700_R60","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/9629","article-title":"A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans.","volume":"22","author":"Achermann","year":"1999","journal-title":"Nat Genet"},{"key":"2020071611592878700_R61","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1210\/jcem.87.4.8376","article-title":"Gonadal determination and adrenal development are regulated by the orphan nuclear receptor steroidogenic factor-1, in a dose-dependent manner.","volume":"87","author":"Achermann","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R62","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1210\/jc.2003-031240","article-title":"A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency.","volume":"89","author":"Correa","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R63","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1002\/ajmg.a.31685","article-title":"Ovotestes and XY sex reversal in a female with an interstitial 9q33.3-q34.1 deletion encompassing NR5A1 and LMX1B causing features of Genitopatellar syndrome","volume":"143A","author":"Schlaubitz","year":"2007","journal-title":"Am J Med Genet A"},{"key":"2020071611592878700_R64","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1210\/jc.2006-1672","article-title":"Heterozygous missense mutations in steroidogenic factor 1 (SF1\/Ad4BP, NR5A1) are associated with 46,XY disorders of sex development with normal adrenal function.","volume":"92","author":"Lin","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R65","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/31482","article-title":"Male-to-female sex reversal in M33 mutant mice.","volume":"393","author":"Katoh-Fukui","year":"1998","journal-title":"Nature"},{"key":"2020071611592878700_R66","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1182\/blood-2004-08-3367","article-title":"Mouse Polycomb M33 is required for splenic vascular and adrenal gland formation through regulating Ad4BP\/SF1 expression.","volume":"106","author":"Katoh-Fukui","year":"2005","journal-title":"Blood"},{"key":"2020071611592878700_R67","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.ajhg.2009.03.016","article-title":"Ovaries and female phenotype in a girl with 46,XY karyotype and mutations in the CBX2 gene.","volume":"84","author":"Biason-Lauber","year":"2009","journal-title":"Am J Hum Genet"},{"key":"2020071611592878700_R68","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1242\/dev.01266","article-title":"Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.","volume":"131","author":"Cui","year":"2004","journal-title":"Development"},{"key":"2020071611592878700_R69","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/jez.1400370303","article-title":"Studies in mammalian spermatogenesis. II. The spermatogenesis of man.","volume":"37","author":"Painter","year":"1923","journal-title":"J Exp Zool"},{"key":"2020071611592878700_R70","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0140-6736(59)91893-8","article-title":"A sex-chromosome anomaly in a case of gonadal dysgenesis (Turner\u2019s syndrome).","volume":"1","author":"Ford","year":"1959","journal-title":"The Lancet"},{"key":"2020071611592878700_R71","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/183302a0","article-title":"A case of human intersexuality having a possible XXY sex-determining mechanism.","volume":"183","author":"Jacobs","year":"1959","journal-title":"Nature"},{"key":"2020071611592878700_R72","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/346240a0","article-title":"A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif.","volume":"346","author":"Sinclair","year":"1990","journal-title":"Nature"},{"key":"2020071611592878700_R73","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/346245a0","article-title":"A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.","volume":"346","author":"Gubbay","year":"1990","journal-title":"Nature"},{"key":"2020071611592878700_R74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00009.2006","article-title":"Sex determination and gonadal development in mammals.","volume":"87","author":"Wilhelm","year":"2007","journal-title":"Physiol Rev"},{"key":"2020071611592878700_R75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1210\/me.2007-0250","article-title":"SRY and the standoff in sex determination.","volume":"22","author":"DiNapoli","year":"2008","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R76","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.tig.2008.10.008","article-title":"Sex determination and SRY: down to a wink and a nudge?","volume":"25","author":"Sekido","year":"2009","journal-title":"Trends Genet"},{"key":"2020071611592878700_R77","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ydbio.2004.07.011","article-title":"SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.","volume":"274","author":"Sekido","year":"2004","journal-title":"Dev Biol"},{"key":"2020071611592878700_R78","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1038\/nature06944","article-title":"Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.","volume":"453","author":"Sekido","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R79","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/372525a0","article-title":"Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene.","volume":"372","author":"Foster","year":"1994","journal-title":"Nature"},{"key":"2020071611592878700_R80","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/0092-8674(94)90041-8","article-title":"Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9.","volume":"79","author":"Wagner","year":"1994","journal-title":"Cell"},{"key":"2020071611592878700_R81","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/(SICI)1096-8628(19991203)87:4<349::AID-AJMG13>3.0.CO;2-N","article-title":"Autosomal XX sex reversal caused by duplication of SOX9.","volume":"87","author":"Huang","year":"1999","journal-title":"Am J Med Genet"},{"key":"2020071611592878700_R82","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1210\/mend.16.3.0782","article-title":"Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins.","volume":"16","author":"Shen","year":"2002","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R83","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0092-8674(01)00284-7","article-title":"Male-to-female sex reversal in mice lacking fibroblast growth factor 9.","volume":"104","author":"Colvin","year":"2001","journal-title":"Cell"},{"key":"2020071611592878700_R84","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1242\/dev.01239","article-title":"Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.","volume":"131","author":"Schmahl","year":"2004","journal-title":"Development"},{"key":"2020071611592878700_R85","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1371\/journal.pbio.0040187","article-title":"Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination","volume":"4","author":"Kim","year":"2006","journal-title":"PLoS Biol"},{"key":"2020071611592878700_R86","doi-asserted-by":"crossref","first-page":"16558","DOI":"10.1073\/pnas.0702581104","article-title":"Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination.","volume":"104","author":"Kim","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R87","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ydbio.2007.11.010","article-title":"Loss of Fgfr2 leads to partial XY sex reversal.","volume":"314","author":"Bagheri-Fam","year":"2008","journal-title":"Dev Biol"},{"key":"2020071611592878700_R88","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1111\/j.1432-1033.1993.tb18432.x","article-title":"Control of sex determination in animals.","volume":"218","author":"McElreavey","year":"1993","journal-title":"Eur J Biochem"},{"key":"2020071611592878700_R89","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev.ge.27.120193.000443","article-title":"SRY and sex determination in mammals.","volume":"27","author":"Goodfellow","year":"1993","journal-title":"Annu Rev Genet"},{"key":"2020071611592878700_R90","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1038\/ng1907","article-title":"R-spondin1 is essential in sex determination, skin differentiation and malignancy.","volume":"38","author":"Parma","year":"2006","journal-title":"Nat Genet"},{"key":"2020071611592878700_R91","doi-asserted-by":"crossref","first-page":"14700","DOI":"10.1073\/pnas.0702305104","article-title":"R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6.","volume":"104","author":"Binnerts","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R92","doi-asserted-by":"crossref","first-page":"15903","DOI":"10.1074\/jbc.M701927200","article-title":"R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and \u03b2-catenin signaling.","volume":"282","author":"Wei","year":"2007","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R93","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/hmg\/ddn016","article-title":"Activation of \u03b2-catenin signaling by Rspo1 controls differentiation of the mammalian ovary.","volume":"17","author":"Chassot","year":"2008","journal-title":"Hum Mol Genet"},{"key":"2020071611592878700_R94","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1093\/hmg\/ddn036","article-title":"R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling.","volume":"17","author":"Tomizuka","year":"2008","journal-title":"Hum Mol Genet"},{"key":"2020071611592878700_R95","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/17068","article-title":"Female development in mammals is regulated by Wnt-4 signalling.","volume":"397","author":"Vainio","year":"1999","journal-title":"Nature"},{"key":"2020071611592878700_R96","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/hmg\/ddn193","article-title":"Stabilization of \u03b2-catenin in XY gonads causes male-to-female sex-reversal.","volume":"17","author":"Maatouk","year":"2008","journal-title":"Hum Mol Genet"},{"key":"2020071611592878700_R97","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/hmg\/ddn362","article-title":"Sex-specific roles of \u03b2-catenin in mouse gonadal development.","volume":"18","author":"Liu","year":"2009","journal-title":"Hum Mol Genet"},{"key":"2020071611592878700_R98","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/dvdy.20042","article-title":"Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.","volume":"230","author":"Yao","year":"2004","journal-title":"Dev Dyn"},{"key":"2020071611592878700_R99","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1242\/dev.024653","article-title":"Ovarian development in mice requires the GATA4-FOG2 transcription complex.","volume":"135","author":"Manuylov","year":"2008","journal-title":"Development"},{"key":"2020071611592878700_R100","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S1567-133X(02)00022-4","article-title":"Sexually dimorphic gene expression in the developing mouse gonad.","volume":"2","author":"Menke","year":"2002","journal-title":"Gene Expr Patterns"},{"key":"2020071611592878700_R101","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1016\/j.biocel.2008.06.006","article-title":"Human SRY inhibits \u03b2-catenin-mediated transcription.","volume":"40","author":"Bernard","year":"2008","journal-title":"Int J Biochem Cell Biol"},{"key":"2020071611592878700_R102","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1086\/320125","article-title":"Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.","volume":"68","author":"Jordan","year":"2001","journal-title":"Am J Hum Genet"},{"key":"2020071611592878700_R103","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1006\/bbrc.1998.8530","article-title":"The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.","volume":"245","author":"Seligman","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"2020071611592878700_R104","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1126\/science.1166340","article-title":"Germ cell-intrinsic and -extrinsic factors govern meiotic initiation in mouse embryos.","volume":"322","author":"Lin","year":"2008","journal-title":"Science"},{"key":"2020071611592878700_R105","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1126\/science.1125691","article-title":"Retinoid signaling determines germ cell fate in mice.","volume":"312","author":"Bowles","year":"2006","journal-title":"Science"},{"key":"2020071611592878700_R106","doi-asserted-by":"crossref","first-page":"14976","DOI":"10.1073\/pnas.0807297105","article-title":"Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.","volume":"105","author":"Anderson","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R107","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1261\/rna.465507","article-title":"Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.","volume":"13","author":"Reynolds","year":"2007","journal-title":"RNA"},{"key":"2020071611592878700_R108","doi-asserted-by":"crossref","first-page":"4560","DOI":"10.1210\/en.2007-0492","article-title":"Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice.","volume":"148","author":"MacLean","year":"2007","journal-title":"Endocrinology"},{"key":"2020071611592878700_R109","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0012-1606(03)00391-9","article-title":"Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave.","volume":"262","author":"Menke","year":"2003","journal-title":"Dev Biol"},{"key":"2020071611592878700_R110","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1038\/ng1919","article-title":"In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication.","volume":"38","author":"Baltus","year":"2006","journal-title":"Nat Genet"},{"key":"2020071611592878700_R111","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1101\/gad.1612708","article-title":"Nanos2 suppresses meiosis and promotes male germ cell differentiation.","volume":"22","author":"Suzuki","year":"2008","journal-title":"Genes Dev"},{"key":"2020071611592878700_R112","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1098\/rspb.1963.0055","article-title":"A quantitative and cytological study of germ cells in human ovaries.","volume":"158","author":"Baker","year":"1963","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"2020071611592878700_R113","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0074-7696(08)61524-7","article-title":"Development of follicles in the mammalian ovary.","volume":"124","author":"Hirshfield","year":"1991","journal-title":"Int Rev Cytol"},{"key":"2020071611592878700_R114","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1530\/rep.0.1220829","article-title":"Oocyte control of ovarian follicular development and function in mammals.","volume":"122","author":"Eppig","year":"2001","journal-title":"Reproduction"},{"key":"2020071611592878700_R115","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1126\/science.1071965","article-title":"Intercellular communication in the mammalian ovary: oocytes carry the conversation.","volume":"296","author":"Matzuk","year":"2002","journal-title":"Science"},{"key":"2020071611592878700_R116","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1242\/dev.125.17.3323","article-title":"Female mouse germ cells form synchronously dividing cysts.","volume":"125","author":"Pepling","year":"1998","journal-title":"Development"},{"key":"2020071611592878700_R117","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/dbio.2001.0269","article-title":"Mouse ovarian germ cell cysts undergo programmed breakdown to form primordial follicles.","volume":"234","author":"Pepling","year":"2001","journal-title":"Dev Biol"},{"key":"2020071611592878700_R118","doi-asserted-by":"crossref","first-page":"4982","DOI":"10.1073\/pnas.0505123103","article-title":"TEX14 is essential for intercellular bridges and fertility in male mice.","volume":"103","author":"Greenbaum","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R119","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1095\/biolreprod.108.070649","article-title":"Mouse TEX14 is required for embryonic germ cell intercellular bridges but not female fertility.","volume":"80","author":"Greenbaum","year":"2009","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R120","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/91039","article-title":"Eggs in the balance.","volume":"28","author":"Matzuk","year":"2001","journal-title":"Nat Genet"},{"key":"2020071611592878700_R121","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1210\/endo.136.8.7628407","article-title":"Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the postnatal female mouse gonad.","volume":"136","author":"Ratts","year":"1995","journal-title":"Endocrinology"},{"key":"2020071611592878700_R122","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1210\/mend.14.7.0465","article-title":"Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis.","volume":"14","author":"Rucker 3rd","year":"2000","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R123","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1530\/REP-06-0270","article-title":"BAX regulates follicular endowment in mice.","volume":"133","author":"Greenfeld","year":"2007","journal-title":"Reproduction"},{"key":"2020071611592878700_R124","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/5985","article-title":"Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency.","volume":"21","author":"Perez","year":"1999","journal-title":"Nat Genet"},{"key":"2020071611592878700_R125","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/ng575","article-title":"Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals.","volume":"28","author":"Matikainen","year":"2001","journal-title":"Nat Genet"},{"key":"2020071611592878700_R126","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/toxsci\/56.2.382","article-title":"Physiological role of the aryl hydrocarbon receptor in mouse ovary development.","volume":"56","author":"Benedict","year":"2000","journal-title":"Toxicol Sci"},{"key":"2020071611592878700_R127","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1210\/endo.141.1.7374","article-title":"The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse.","volume":"141","author":"Robles","year":"2000","journal-title":"Endocrinology"},{"key":"2020071611592878700_R128","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1101\/gad.12.9.1304","article-title":"Defects in regulation of apoptosis in caspase-2-deficient mice.","volume":"12","author":"Bergeron","year":"1998","journal-title":"Genes Dev"},{"key":"2020071611592878700_R129","doi-asserted-by":"crossref","first-page":"4645","DOI":"10.1242\/dev.127.21.4645","article-title":"FIG\u03b1, a germ cell-specific transcription factor required for ovarian follicle formation.","volume":"127","author":"Soyal","year":"2000","journal-title":"Development"},{"key":"2020071611592878700_R130","doi-asserted-by":"crossref","first-page":"4939","DOI":"10.1242\/dev.124.24.4939","article-title":"FIG\u03b1, a germ cell specific transcription factor involved in the coordinate expression of the zona pellucida genes.","volume":"124","author":"Liang","year":"1997","journal-title":"Development"},{"key":"2020071611592878700_R131","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1242\/dev.128.7.1119","article-title":"Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development.","volume":"128","author":"Rankin","year":"2001","journal-title":"Development"},{"key":"2020071611592878700_R132","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1242\/dev.126.17.3847","article-title":"Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss.","volume":"126","author":"Rankin","year":"1999","journal-title":"Development"},{"key":"2020071611592878700_R133","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1242\/dev.122.9.2903","article-title":"Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile.","volume":"122","author":"Rankin","year":"1996","journal-title":"Development"},{"key":"2020071611592878700_R134","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/molehr\/gah056","article-title":"Increased expression of the FIGLA transcription factor is associated with primordial follicle formation in the human fetal ovary.","volume":"10","author":"Bayne","year":"2004","journal-title":"Mol Hum Reprod"},{"key":"2020071611592878700_R135","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1093\/molehr\/8.12.1087","article-title":"Isolation, characterization and expression of the human factor in the germline \u03b1 (FIGLA) gene in ovarian follicles and oocytes.","volume":"8","author":"Huntriss","year":"2002","journal-title":"Mol Hum Reprod"},{"key":"2020071611592878700_R136","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1471-213X-7-67","article-title":"Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor.","volume":"7","author":"Joshi","year":"2007","journal-title":"BMC Dev Biol"},{"key":"2020071611592878700_R137","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/(SICI)1521-1878(199809)20:9<722::AID-BIES5>3.0.CO;2-I","article-title":"In line with our ancestors: Oct-4 and the mammalian germ.","volume":"20","author":"Pesce","year":"1998","journal-title":"Bioessays"},{"key":"2020071611592878700_R138","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/81547","article-title":"Mater, a maternal effect gene required for early embryonic development in mice.","volume":"26","author":"Tong","year":"2000","journal-title":"Nat Genet"},{"key":"2020071611592878700_R139","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1095\/biolreprod43.3.478","article-title":"Polyovular follicles in mouse ovaries exposed neonatally to diethylstilbestrol in vivo and in vitro.","volume":"43","author":"Iguchi","year":"1990","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R140","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/tera.1420340105","article-title":"Frequent occurrence of polyovular follicles in ovaries of mice exposed neonatally to diethylstilbestrol.","volume":"34","author":"Iguchi","year":"1986","journal-title":"Teratology"},{"key":"2020071611592878700_R141","doi-asserted-by":"crossref","first-page":"3580","DOI":"10.1210\/en.2007-0088","article-title":"Estradiol, progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo.","volume":"148","author":"Chen","year":"2007","journal-title":"Endocrinology"},{"key":"2020071611592878700_R142","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1210\/en.2002-0131","article-title":"Regulation of ovarian primordial follicle assembly and development by estrogen and progesterone: endocrine model of follicle assembly.","volume":"144","author":"Kezele","year":"2003","journal-title":"Endocrinology"},{"key":"2020071611592878700_R143","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1095\/biolreprod.104.028175","article-title":"Estrogen actions on follicle formation and early follicle development.","volume":"71","author":"Britt","year":"2004","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R144","doi-asserted-by":"crossref","first-page":"6965","DOI":"10.1073\/pnas.95.12.6965","article-title":"Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene.","volume":"95","author":"Fisher","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R145","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1101\/gad.9.18.2266","article-title":"Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.","volume":"9","author":"Lydon","year":"1995","journal-title":"Genes Dev"},{"key":"2020071611592878700_R146","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1095\/biolreprod67.4.1148","article-title":"Developmental regulation of baboon fetal ovarian maturation by estrogen.","volume":"67","author":"Zachos","year":"2002","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R147","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nrm2009","article-title":"Notch signalling: a simple pathway becomes complex.","volume":"7","author":"Bray","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2020071611592878700_R148","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1210\/en.2008-0213","article-title":"Suppression of Notch signaling in the neonatal mouse ovary decreases primordial follicle formation.","volume":"150","author":"Trombly","year":"2009","journal-title":"Endocrinology"},{"key":"2020071611592878700_R149","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1242\/dev.01601","article-title":"Lunatic fringe null female mice are infertile due to defects in meiotic maturation.","volume":"132","author":"Hahn","year":"2005","journal-title":"Development"},{"key":"2020071611592878700_R150","first-page":"200","article-title":"Initial and cyclic recruitment of ovarian follicles.","volume":"21","author":"McGee","year":"2000","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R151","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0015-0282(01)01966-5","article-title":"Discovery of germ cell-specific transcripts by expressed sequence tag database analysis.","volume":"76","author":"Rajkovic","year":"2001","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R152","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.modgep.2006.04.007","article-title":"Sohlh2 is a germ cell-specific bHLH transcription factor.","volume":"6","author":"Ballow","year":"2006","journal-title":"Gene Expr Patterns"},{"key":"2020071611592878700_R153","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1095\/biolreprod.108.071217","article-title":"Germ cell-specific transcriptional regulator sohlh2 is essential for early mouse folliculogenesis and oocyte-specific gene expression.","volume":"79","author":"Choi","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R154","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1634\/stemcells.2007-0502","article-title":"Sohlh2 knockout mice are male-sterile because of degeneration of differentiating type A spermatogonia.","volume":"26","author":"Hao","year":"2008","journal-title":"Stem Cells"},{"key":"2020071611592878700_R155","doi-asserted-by":"crossref","first-page":"8090","DOI":"10.1073\/pnas.0601083103","article-title":"Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8.","volume":"103","author":"Pangas","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R156","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1126\/science.1099755","article-title":"NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.","volume":"305","author":"Rajkovic","year":"2004","journal-title":"Science"},{"key":"2020071611592878700_R157","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1095\/biolreprod.107.060459","article-title":"Microarray analyses of newborn mouse ovaries lacking Nobox.","volume":"77","author":"Choi","year":"2007","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R158","doi-asserted-by":"crossref","first-page":"35747","DOI":"10.1074\/jbc.M604008200","article-title":"Characterization of NOBOX DNA binding specificity and its regulation of Gdf9 and Pou5f1 promoters.","volume":"281","author":"Choi","year":"2006","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R159","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1095\/biolreprod.108.069393","article-title":"Lim homeobox gene, lhx8, is essential for mouse oocyte differentiation and survival.","volume":"79","author":"Choi","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R160","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.ydbio.2008.10.019","article-title":"Sohlh2 affects differentiation of KIT positive oocytes and spermatogonia.","volume":"325","author":"Toyoda","year":"2009","journal-title":"Dev Biol"},{"key":"2020071611592878700_R161","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1095\/biolreprod45.4.547","article-title":"The expression of c-kit protein during oogenesis and early embryonic development.","volume":"45","author":"Horie","year":"1991","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R162","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1006\/dbio.1999.9437","article-title":"Oocyte regulation of kit ligand expression in mouse ovarian follicles.","volume":"214","author":"Joyce","year":"1999","journal-title":"Dev Biol"},{"key":"2020071611592878700_R163","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1006\/dbio.1993.1114","article-title":"The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia.","volume":"157","author":"Manova","year":"1993","journal-title":"Dev Biol"},{"key":"2020071611592878700_R164","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1242\/dev.110.4.1057","article-title":"Gonadal expression of c-kit encoded at the W locus of the mouse.","volume":"110","author":"Manova","year":"1990","journal-title":"Development"},{"key":"2020071611592878700_R165","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1006\/dbio.1997.8503","article-title":"Stepwise requirement of c-kit tyrosine kinase in mouse ovarian follicle development.","volume":"184","author":"Yoshida","year":"1997","journal-title":"Dev Biol"},{"key":"2020071611592878700_R166","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1101\/gad.9.4.455","article-title":"DNA rearrangements located over 100 kb 5\u2032 of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development.","volume":"9","author":"Bedell","year":"1995","journal-title":"Genes Dev"},{"key":"2020071611592878700_R167","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/dbio.1993.1115","article-title":"The murine steel panda mutation affects kit ligand expression and growth of early ovarian follicles.","volume":"157","author":"Huang","year":"1993","journal-title":"Dev Biol"},{"key":"2020071611592878700_R168","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0012-1606(88)90240-0","article-title":"Infertility due to growth arrest of ovarian follicles in Sl\/Slt mice.","volume":"126","author":"Kuroda","year":"1988","journal-title":"Dev Biol"},{"key":"2020071611592878700_R169","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.1210\/endo.140.9.6994","article-title":"Kit-ligand\/stem cell factor induces primordial follicle development and initiates folliculogenesis.","volume":"140","author":"Parrott","year":"1999","journal-title":"Endocrinology"},{"key":"2020071611592878700_R170","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0092-8674(04)00452-0","article-title":"FoxOs at the crossroads of cellular metabolism, differentiation, and transformation.","volume":"117","author":"Accili","year":"2004","journal-title":"Cell"},{"key":"2020071611592878700_R171","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ydbio.2005.02.013","article-title":"Activation of Akt (PKB) and suppression of FKHRL1 in mouse and rat oocytes by stem cell factor during follicular activation and development.","volume":"281","author":"Reddy","year":"2005","journal-title":"Dev Biol"},{"key":"2020071611592878700_R172","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1126\/science.1086336","article-title":"Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a.","volume":"301","author":"Castrillon","year":"2003","journal-title":"Science"},{"key":"2020071611592878700_R173","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1073\/pnas.0400093101","article-title":"Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification.","volume":"101","author":"Hosaka","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R174","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1210\/mend.16.3.0806","article-title":"Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins.","volume":"16","author":"Richards","year":"2002","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R175","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1210\/me.2008-0412","article-title":"FSH and FOXO1 regulate genes in the sterol\/steroid and lipid biosynthetic pathways in granulosa cells.","volume":"23","author":"Liu","year":"2009","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R176","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1242\/dev.02667","article-title":"Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a.","volume":"134","author":"Liu","year":"2007","journal-title":"Development"},{"key":"2020071611592878700_R177","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ydbio.2008.06.017","article-title":"Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth.","volume":"321","author":"John","year":"2008","journal-title":"Dev Biol"},{"key":"2020071611592878700_R178","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1126\/science.1152257","article-title":"Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool.","volume":"319","author":"Reddy","year":"2008","journal-title":"Science"},{"key":"2020071611592878700_R179","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1093\/emboj\/19.6.1312","article-title":"Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses.","volume":"19","author":"Kissel","year":"2000","journal-title":"EMBO J"},{"key":"2020071611592878700_R180","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.molmed.2003.09.003","article-title":"FoxO3a eggs on fertility and aging.","volume":"9","author":"Brenkman","year":"2003","journal-title":"Trends Mol Med"},{"key":"2020071611592878700_R181","doi-asserted-by":"crossref","first-page":"9138","DOI":"10.1128\/MCB.20.24.9138-9148.2000","article-title":"Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).","volume":"20","author":"Dijkers","year":"2000","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R182","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1210\/me.2007-0172","article-title":"p27kip1 (cyclin-dependent kinase inhibitor 1B) controls ovarian development by suppressing follicle endowment and activation and promoting follicle atresia in mice.","volume":"21","author":"Rajareddy","year":"2007","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R183","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.semcdb.2003.12.022","article-title":"PDK1, the master regulator of AGC kinase signal transduction.","volume":"15","author":"Mora","year":"2004","journal-title":"Semin Cell Dev Biol"},{"key":"2020071611592878700_R184","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1093\/hmg\/ddp217","article-title":"PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles.","volume":"18","author":"Reddy","year":"2009","journal-title":"Hum Mol Genet"},{"key":"2020071611592878700_R185","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1126\/science.288.5473.2045","article-title":"Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6.","volume":"288","author":"Volarevic","year":"2000","journal-title":"Science"},{"key":"2020071611592878700_R186","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/84781","article-title":"The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis\/ptosis\/epicanthus inversus syndrome.","volume":"27","author":"Crisponi","year":"2001","journal-title":"Nat Genet"},{"key":"2020071611592878700_R187","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1242\/dev.00969","article-title":"The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance.","volume":"131","author":"Schmidt","year":"2004","journal-title":"Development"},{"key":"2020071611592878700_R188","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/hmg\/ddh124","article-title":"Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development.","volume":"13","author":"Uda","year":"2004","journal-title":"Hum Mol Genet"},{"key":"2020071611592878700_R189","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0092-8674(94)90251-8","article-title":"Mullerian-inhibiting substance function during mammalian sexual development.","volume":"79","author":"Behringer","year":"1994","journal-title":"Cell"},{"key":"2020071611592878700_R190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1530\/rep.1.00529","article-title":"Anti-Mullerian hormone: a new marker for ovarian function.","volume":"131","author":"Visser","year":"2006","journal-title":"Reproduction"},{"key":"2020071611592878700_R191","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1101\/gad.10.20.2577","article-title":"Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation.","volume":"10","author":"Mishina","year":"1996","journal-title":"Genes Dev"},{"key":"2020071611592878700_R192","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.1210\/endo.140.12.7204","article-title":"Control of primordial follicle recruitment by anti-Mullerian hormone in the mouse ovary.","volume":"140","author":"Durlinger","year":"1999","journal-title":"Endocrinology"},{"key":"2020071611592878700_R193","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1210\/endo.143.3.8691","article-title":"Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary.","volume":"143","author":"Durlinger","year":"2002","journal-title":"Endocrinology"},{"key":"2020071611592878700_R194","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0015-0282(01)02993-4","article-title":"Antimullerian hormone serum levels: a putative marker for ovarian aging.","volume":"77","author":"Vet","year":"2002","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R195","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1210\/en.2005-1588","article-title":"Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice.","volume":"147","author":"Kevenaar","year":"2006","journal-title":"Endocrinology"},{"key":"2020071611592878700_R196","doi-asserted-by":"crossref","first-page":"4681","DOI":"10.1210\/endo.136.10.7664689","article-title":"Expression of neurotrophins and their receptors in the mammalian ovary is developmentally regulated: changes at the time of folliculogenesis.","volume":"136","author":"Dissen","year":"1995","journal-title":"Endocrinology"},{"key":"2020071611592878700_R197","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1055\/s-0028-1108007","article-title":"Role of neurotrophic factors in early ovarian development.","volume":"27","author":"Dissen","year":"2009","journal-title":"Semin Reprod Med"},{"key":"2020071611592878700_R198","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1210\/endo.142.5.8126","article-title":"Nerve growth factor is required for early follicular development in the mammalian ovary.","volume":"142","author":"Dissen","year":"2001","journal-title":"Endocrinology"},{"key":"2020071611592878700_R199","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/0092-8674(92)90286-L","article-title":"Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system.","volume":"69","author":"Lee","year":"1992","journal-title":"Cell"},{"key":"2020071611592878700_R200","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1073\/pnas.040562597","article-title":"Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice.","volume":"97","author":"Liebl","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R201","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/368246a0","article-title":"Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk\/NGF receptor gene.","volume":"368","author":"Smeyne","year":"1994","journal-title":"Nature"},{"key":"2020071611592878700_R202","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.ydbio.2003.12.001","article-title":"TrkB receptors are required for follicular growth and oocyte survival in the mammalian ovary.","volume":"267","author":"Paredes","year":"2004","journal-title":"Dev Biol"},{"key":"2020071611592878700_R203","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1530\/REP-07-0405","article-title":"Glial-derived neurotrophic factor promotes ovarian primordial follicle development and cell-cell interactions during folliculogenesis.","volume":"135","author":"Dole","year":"2008","journal-title":"Reproduction"},{"key":"2020071611592878700_R204","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1530\/rep.1.00978","article-title":"Platelet-derived growth factor modulates the primordial to primary follicle transition.","volume":"131","author":"Nilsson","year":"2006","journal-title":"Reproduction"},{"key":"2020071611592878700_R205","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1093\/humupd\/dmi020","article-title":"Regulation of primordial follicle assembly and development.","volume":"11","author":"Skinner","year":"2005","journal-title":"Hum Reprod Update"},{"key":"2020071611592878700_R206","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1095\/biolreprod65.4.994","article-title":"Effect of bone morphogenetic protein-7 on folliculogenesis and ovulation in the rat.","volume":"65","author":"Lee","year":"2001","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R207","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0303-7207(01)00746-8","article-title":"Leukemia inhibitory factor (LIF) promotes the primordial to primary follicle transition in rat ovaries.","volume":"188","author":"Nilsson","year":"2002","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R208","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.ydbio.2006.02.012","article-title":"CXCR4\/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary.","volume":"293","author":"Holt","year":"2006","journal-title":"Dev Biol"},{"key":"2020071611592878700_R209","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.1242\/dev.00640","article-title":"The chemokine SDF1\/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival.","volume":"130","author":"Molyneaux","year":"2003","journal-title":"Development"},{"key":"2020071611592878700_R210","doi-asserted-by":"crossref","first-page":"5672","DOI":"10.1073\/pnas.95.10.5672","article-title":"Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2.","volume":"95","author":"Ortega","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R211","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1101\/gad.10.2.165","article-title":"Keratinocyte growth factor is required for hair development but not for wound healing.","volume":"10","author":"Guo","year":"1996","journal-title":"Genes Dev"},{"key":"2020071611592878700_R212","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/359076a0","article-title":"Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor.","volume":"359","author":"Stewart","year":"1992","journal-title":"Nature"},{"key":"2020071611592878700_R213","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1056\/NEJMcp0808697","article-title":"Clinical practice. Primary ovarian insufficiency.","volume":"360","author":"Nelson","year":"2009","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R214","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1086\/519496","article-title":"NOBOX homeobox mutation causes premature ovarian failure.","volume":"81","author":"Qin","year":"2007","journal-title":"Am J Hum Genet"},{"key":"2020071611592878700_R215","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.ajhg.2008.04.018","article-title":"Transcription factor FIGLA is mutated in patients with premature ovarian failure.","volume":"82","author":"Zhao","year":"2008","journal-title":"Am J Hum Genet"},{"key":"2020071611592878700_R216","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/ng0297-201","article-title":"Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility.","volume":"15","author":"Kumar","year":"1997","journal-title":"Nat Genet"},{"key":"2020071611592878700_R217","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1210\/endo.141.5.7456","article-title":"The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction.","volume":"141","author":"Abel","year":"2000","journal-title":"Endocrinology"},{"key":"2020071611592878700_R218","doi-asserted-by":"crossref","first-page":"13612","DOI":"10.1073\/pnas.95.23.13612","article-title":"Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance.","volume":"95","author":"Dierich","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R219","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/269338a0","article-title":"Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism.","volume":"269","author":"Cattanach","year":"1977","journal-title":"Nature"},{"key":"2020071611592878700_R220","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.1073\/pnas.052658699","article-title":"The mammalian oocyte orchestrates the rate of ovarian follicular development.","volume":"99","author":"Eppig","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R221","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1210\/mend.13.6.0310","article-title":"Paracrine actions of growth differentiation factor-9 in the mammalian ovary.","volume":"13","author":"Elvin","year":"1999","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R222","first-page":"131","article-title":"Oocyte-specific expression of growth\/differentiation factor-9.","volume":"9","author":"McGrath","year":"1995","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R223","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/383531a0","article-title":"Growth differentiation factor-9 is required during early ovarian folliculogenesis.","volume":"383","author":"Dong","year":"1996","journal-title":"Nature"},{"key":"2020071611592878700_R224","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/dbio.1998.9087","article-title":"Characterization of oocyte and follicle development in growth differentiation factor-9-deficient mice.","volume":"204","author":"Carabatsos","year":"1998","journal-title":"Dev Biol"},{"key":"2020071611592878700_R225","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1210\/mend.13.6.0309","article-title":"Molecular characterization of the follicle defects in the growth differentiation factor 9-deficient ovary.","volume":"13","author":"Elvin","year":"1999","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R226","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1210\/me.2003-0399","article-title":"Interrelationship of growth differentiation factor 9 and inhibin in early folliculogenesis and ovarian tumorigenesis in mice.","volume":"18","author":"Wu","year":"2004","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R227","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1006\/dbio.1994.1020","article-title":"The ligand of the c-kit receptor promotes oocyte growth.","volume":"161","author":"Packer","year":"1994","journal-title":"Dev Biol"},{"key":"2020071611592878700_R228","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1095\/biolreprod63.6.1669","article-title":"Comparison of recombinant growth differentiation factor-9 and oocyte regulation of KIT ligand messenger ribonucleic acid expression in mouse ovarian follicles.","volume":"63","author":"Joyce","year":"2000","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R229","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1210\/mend.12.12.0206","article-title":"The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes.","volume":"12","author":"Dube","year":"1998","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R230","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1210\/mend.15.6.0662","article-title":"Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function.","volume":"15","author":"Yan","year":"2001","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R231","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1095\/biolreprod.103.023093","article-title":"Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries).","volume":"70","author":"Hanrahan","year":"2004","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R232","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mce.2004.08.013","article-title":"Oocyte-expressed genes affecting ovulation rate.","volume":"234","author":"McNatty","year":"2005","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R233","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1095\/biolreprod49.5.895","article-title":"Ovaries of ewes homozygous for the X-linked Inverdale gene (FecXI) are devoid of secondary and tertiary follicles but contain many abnormal structures.","volume":"49","author":"Braw-Tal","year":"1993","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R234","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/77033","article-title":"Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner.","volume":"25","author":"Galloway","year":"2000","journal-title":"Nat Genet"},{"key":"2020071611592878700_R235","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.1074\/jbc.M210598200","article-title":"Effect of intracellular interactions on the processing and secretion of bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9. Implication of the aberrant ovarian phenotype of BMP-15 mutant sheep.","volume":"278","author":"Liao","year":"2003","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R236","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1086\/422103","article-title":"Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene.","volume":"75","author":"Di Pasquale","year":"2004","journal-title":"Am J Hum Genet"},{"key":"2020071611592878700_R237","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.fertnstert.2006.05.079","article-title":"Growth differentiating factor-9 mutations may be associated with premature ovarian failure.","volume":"87","author":"Kovanci","year":"2007","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R238","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1530\/eje.1.02135","article-title":"Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure.","volume":"154","author":"Laissue","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"2020071611592878700_R239","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1002\/humu.20961","article-title":"BMP15 mutations associated with primary ovarian insufficiency cause a defective production of bioactive protein.","volume":"30","author":"Rossetti","year":"2009","journal-title":"Hum Mutat"},{"key":"2020071611592878700_R240","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.fertnstert.2007.01.021","article-title":"Analyses of GDF9 mutation in 100 Chinese women with premature ovarian failure.","volume":"88","author":"Zhao","year":"2007","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R241","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1210\/jcem.87.2.8221","article-title":"Neurotropins and their receptors are expressed in the human fetal ovary.","volume":"87","author":"Anderson","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R242","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.mce.2007.11.001","article-title":"Gap junctions in the ovary: expression, localization and function.","volume":"282","author":"Gershon","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R243","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1530\/rep.0.1230613","article-title":"Gap junctions and ovarian folliculogenesis.","volume":"123","author":"Kidder","year":"2002","journal-title":"Reproduction"},{"key":"2020071611592878700_R244","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1095\/biolreprod60.5.1263","article-title":"Defects in the germ line and gonads of mice lacking connexin43.","volume":"60","author":"Juneja","year":"1999","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R245","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/385525a0","article-title":"Female infertility in mice lacking connexin 37.","volume":"385","author":"Simon","year":"1997","journal-title":"Nature"},{"key":"2020071611592878700_R246","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1126\/science.7892609","article-title":"Cardiac malformation in neonatal mice lacking connexin43.","volume":"267","author":"Reaume","year":"1995","journal-title":"Science"},{"key":"2020071611592878700_R247","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1006\/dbio.2001.0216","article-title":"Intercellular communication via connexin43 gap junctions is required for ovarian folliculogenesis in the mouse.","volume":"233","author":"Ackert","year":"2001","journal-title":"Dev Biol"},{"key":"2020071611592878700_R248","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1006\/dbio.2000.9863","article-title":"Oocyte-granulosa cell heterologous gap junctions are required for the coordination of nuclear and cytoplasmic meiotic competence.","volume":"226","author":"Carabatsos","year":"2000","journal-title":"Dev Biol"},{"key":"2020071611592878700_R249","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.biocel.2005.01.016","article-title":"Ovarian theca cell.","volume":"37","author":"Magoffin","year":"2005","journal-title":"Int J Biochem Cell Biol"},{"key":"2020071611592878700_R250","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1095\/biolreprod44.6.1157","article-title":"Theca cells may be present at the outset of follicular growth.","volume":"44","author":"Hirshfield","year":"1991","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R251","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1095\/biolreprod55.2.416","article-title":"Developmental and hormonal regulation of rat theca-cell differentiation factor secretion in ovarian follicles.","volume":"55","author":"Magarelli","year":"1996","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R252","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1095\/biolreprod64.2.451","article-title":"Stem cell factor and insulin-like growth factor-I stimulate luteinizing hormone-independent differentiation of rat ovarian theca cells.","volume":"64","author":"Huang","year":"2001","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R253","doi-asserted-by":"crossref","first-page":"32281","DOI":"10.1074\/jbc.M403212200","article-title":"Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin.","volume":"279","author":"Pangas","year":"2004","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R254","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1210\/mend.16.6.0859","article-title":"Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility.","volume":"16","author":"Varani","year":"2002","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R255","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1095\/biolreprod.104.036400","article-title":"Long-term culture of mouse male germline stem cells under serum- or feeder-free conditions.","volume":"72","author":"Kanatsu-Shinohara","year":"2005","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R256","doi-asserted-by":"crossref","first-page":"12389","DOI":"10.1073\/pnas.0703787104","article-title":"Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells.","volume":"104","author":"Honda","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R257","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1677\/JOE-08-0161","article-title":"Hedgehog signalling in endocrine development and disease.","volume":"198","author":"King","year":"2008","journal-title":"J Endocrinol"},{"key":"2020071611592878700_R258","doi-asserted-by":"crossref","first-page":"3558","DOI":"10.1210\/en.2005-0311","article-title":"Hedgehog signaling in mouse ovary: Indian hedgehog and desert hedgehog from granulosa cells induce target gene expression in developing theca cells.","volume":"146","author":"Wijgerde","year":"2005","journal-title":"Endocrinology"},{"key":"2020071611592878700_R259","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/34201","article-title":"Activating Smoothened mutations in sporadic basal-cell carcinoma.","volume":"391","author":"Xie","year":"1998","journal-title":"Nature"},{"key":"2020071611592878700_R260","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1038\/ng1003","article-title":"Requirement of Bmpr1a for Mullerian duct regression during male sexual development.","volume":"32","author":"Jamin","year":"2002","journal-title":"Nat Genet"},{"key":"2020071611592878700_R261","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1210\/me.2003-0301","article-title":"Granulosa cell-specific inactivation of follistatin causes female fertility defects.","volume":"18","author":"Jorgez","year":"2004","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R262","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1210\/me.2008-0391","article-title":"Dominant activation of the hedgehog signaling pathway in the ovary alters theca development and prevents ovulation.","volume":"23","author":"Ren","year":"2009","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R263","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/cr.2008.302","article-title":"Signaling cross-talk between TGF-\u03b2\/BMP and other pathways.","volume":"19","author":"Guo","year":"2009","journal-title":"Cell Res"},{"key":"2020071611592878700_R264","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1242\/dev.020560","article-title":"Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation.","volume":"135","author":"Fan","year":"2008","journal-title":"Development"},{"key":"2020071611592878700_R265","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1210\/jcem-72-6-1206","article-title":"Effect of recombinant activin on androgen synthesis in cultured human thecal cells.","volume":"72","author":"Hillier","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R266","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1095\/biolreprod53.4.758","article-title":"Granulosa cell modulation of luteinizing hormone-dependent androgen production by ovarian theca-interstitial cells: a temporal switch from suppression to augmentation stimulated by follicle-stimulating hormone in vitro.","volume":"53","author":"Zachow","year":"1995","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R267","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1023\/A:1012700802220","article-title":"perspective.","volume":"3","author":"Magoffin","year":"2001","journal-title":"Rev Endocr Metab Disord"},{"key":"2020071611592878700_R268","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1210\/en.2008-1536","article-title":"Growth differentiation factor 9 promotes rat preantral follicle growth by up-regulating follicular androgen biosynthesis.","volume":"150","author":"Orisaka","year":"2009","journal-title":"Endocrinology"},{"key":"2020071611592878700_R269","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1095\/biolreprod63.4.1214","article-title":"Growth differentiation factor-9 stimulates rat theca-interstitial cell androgen biosynthesis.","volume":"63","author":"Solovyeva","year":"2000","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R270","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1095\/biolreprod.107.063446","article-title":"Growth differentiation factor 9 (GDF9) stimulates proliferation and inhibits steroidogenesis by bovine theca cells: influence of follicle size on responses to GDF9.","volume":"78","author":"Spicer","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R271","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.fertnstert.2008.06.035","article-title":"The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report.","volume":"91","author":"Azziz","year":"2009","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R272","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1210\/er.2008-0030","article-title":"Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review.","volume":"30","author":"Palomba","year":"2009","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R273","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1210\/er.2004-0004","article-title":"The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome.","volume":"26","author":"Escobar-Morreale","year":"2005","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R274","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1242\/jcs.000968","article-title":"Oocytes determine cumulus cell lineage in mouse ovarian follicles.","volume":"120","author":"Diaz","year":"2007","journal-title":"J Cell Sci"},{"key":"2020071611592878700_R275","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1210\/endo.137.4.8625923","article-title":"Hormonal regulation of apoptosis in early antral follicles: follicle-stimulating hormone as a major survival factor.","volume":"137","author":"Chun","year":"1996","journal-title":"Endocrinology"},{"key":"2020071611592878700_R276","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1210\/edrv-15-6-725","article-title":"Hormonal control of gene expression in the ovary.","volume":"15","author":"Richards","year":"1994","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R277","author":"Bernard","year":"2001"},{"key":"2020071611592878700_R278","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1101\/gad.9.16.2007","article-title":"Targeted disruption of the pituitary glycoprotein hormone \u03b1-subunit produces hypogonadal and hypothyroid mice.","volume":"9","author":"Kendall","year":"1995","journal-title":"Genes Dev"},{"key":"2020071611592878700_R279","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/0092-8674(95)90275-9","article-title":"Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure.","volume":"82","author":"Aittom\u00e4ki","year":"1995","journal-title":"Cell"},{"key":"2020071611592878700_R280","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1210\/jcem.87.3.8319","article-title":"A Novel mutation in the FSH receptor inhibiting signal transduction and causing primary ovarian failure.","volume":"87","author":"Doherty","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R281","first-page":"4338","article-title":"The frequency of an inactivating point mutation (566C\u2192T) of the human follicle-stimulating hormone receptor gene in four populations using allele-specific hybridization and time-resolved fluorometry.","volume":"83","author":"Jiang","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R282","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1056\/NEJM199708283370905","article-title":"Delayed puberty and hypogonadism caused by mutations in the follicle-stimulating hormone \u03b2-subunit gene.","volume":"337","author":"Layman","year":"1997","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R283","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/ng0993-83","article-title":"Primary amenorrhoea and infertility due to a mutation in the \u03b2-subunit of follicle-stimulating hormone.","volume":"5","author":"Matthews","year":"1993","journal-title":"Nat Genet"},{"key":"2020071611592878700_R284","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1210\/edrv.21.5.0409","article-title":"Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.","volume":"21","author":"Themmen","year":"2000","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R285","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1210\/endo.139.7.6111","article-title":"Genetic rescue of follicle-stimulating hormone \u03b2-deficient mice.","volume":"139","author":"Kumar","year":"1998","journal-title":"Endocrinology"},{"key":"2020071611592878700_R286","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1210\/rp.57.1.195","article-title":"Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization.","volume":"57","author":"Richards","year":"2002","journal-title":"Recent Prog Horm Res"},{"key":"2020071611592878700_R287","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s12020-008-9041-6","article-title":"Multiple facets of follicle-stimulating hormone receptor function.","volume":"32","author":"Ulloa-Aguirre","year":"2007","journal-title":"Endocrine"},{"key":"2020071611592878700_R288","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1210\/mend.14.8.0500","article-title":"Follicle-stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB\/Akt) and serum and glucocorticoid-induced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells.","volume":"14","author":"Gonzalez-Robayna","year":"2000","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R289","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1210\/me.2007-0020","article-title":"Follicle-stimulating hormone induces multiple signaling cascades: evidence that activation of Rous sarcoma oncogene, RAS, and the epidermal growth factor receptor are critical for granulosa cell differentiation.","volume":"21","author":"Wayne","year":"2007","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R290","first-page":"903","article-title":"Effects of an Igf1 gene null mutation on mouse reproduction.","volume":"10","author":"Baker","year":"1996","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R291","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1210\/mend.11.13.0032","article-title":"Insulin-like growth factor I regulates gonadotropin responsiveness in the murine ovary.","volume":"11","author":"Zhou","year":"1997","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R292","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/384470a0","article-title":"Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.","volume":"384","author":"Sicinski","year":"1996","journal-title":"Nature"},{"key":"2020071611592878700_R293","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1210\/endo.142.7.8279","article-title":"Analysis of ovarian gene expression in follicle-stimulating hormone \u03b2 knockout mice.","volume":"142","author":"Burns","year":"2001","journal-title":"Endocrinology"},{"key":"2020071611592878700_R294","doi-asserted-by":"crossref","first-page":"9135","DOI":"10.1074\/jbc.M409486200","article-title":"Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad.","volume":"280","author":"Park","year":"2005","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R295","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1210\/endo.141.7.7578","article-title":"An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene.","volume":"141","author":"Britt","year":"2000","journal-title":"Endocrinology"},{"key":"2020071611592878700_R296","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1677\/joe.0.1700099","article-title":"Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17\u03b2-oestradiol.","volume":"170","author":"Toda","year":"2001","journal-title":"J Endocrinol"},{"key":"2020071611592878700_R297","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1146\/annurev.physiol.70.113006.100518","article-title":"Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.","volume":"70","author":"Prossnitz","year":"2008","journal-title":"Annu Rev Physiol"},{"key":"2020071611592878700_R298","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1210\/en.2007-1663","article-title":"Estrogen signaling characteristics of Atlantic croaker G protein-coupled receptor 30 (GPR30) and evidence it is involved in maintenance of oocyte meiotic arrest.","volume":"149","author":"Pang","year":"2008","journal-title":"Endocrinology"},{"key":"2020071611592878700_R299","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1095\/biolreprod.108.071175","article-title":"GPR30 does not mediate estrogenic responses in reproductive organs in mice.","volume":"80","author":"Otto","year":"2009","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R300","doi-asserted-by":"crossref","first-page":"11162","DOI":"10.1073\/pnas.90.23.11162","article-title":"Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.","volume":"90","author":"Lubahn","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R301","doi-asserted-by":"crossref","first-page":"15677","DOI":"10.1073\/pnas.95.26.15677","article-title":"Generation and reproductive phenotypes of mice lacking estrogen receptor \u03b2.","volume":"95","author":"Krege","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R302","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1126\/science.286.5448.2328","article-title":"Postnatal sex reversal of the ovaries in mice lacking estrogen receptors \u03b1 and \u03b2.","volume":"286","author":"Couse","year":"1999","journal-title":"Science"},{"key":"2020071611592878700_R303","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1242\/dev.127.19.4277","article-title":"Effect of single and compound knockouts of estrogen receptors \u03b1 (ER\u03b1) and \u03b2 (ER\u03b2) on mouse reproductive phenotypes.","volume":"127","author":"Dupont","year":"2000","journal-title":"Development"},{"key":"2020071611592878700_R304","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0303-7207(03)00055-8","article-title":"Regulation of the phenotype of ovarian somatic cells by estrogen.","volume":"202","author":"Britt","year":"2003","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R305","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1096\/fj.06-6681com","article-title":"Estrogen receptor-\u03b1 mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17\u03b1-hydroxylase\/17,20 lyase) expression.","volume":"21","author":"Taniguchi","year":"2007","journal-title":"FASEB J"},{"key":"2020071611592878700_R306","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1210\/en.2005-0213","article-title":"Estrogen receptor-\u03b2 is critical to granulosa cell differentiation and the ovulatory response to gonadotropins.","volume":"146","author":"Couse","year":"2005","journal-title":"Endocrinology"},{"key":"2020071611592878700_R307","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1210\/endo-99-6-1562","article-title":"Ovarian follicular development in the rat: hormone receptor regulation by estradiol, follicle stimulating hormone and luteinizing hormone.","volume":"99","author":"Richards","year":"1976","journal-title":"Endocrinology"},{"key":"2020071611592878700_R308","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1126\/science.1061935","article-title":"Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.","volume":"293","author":"Freiman","year":"2001","journal-title":"Science"},{"key":"2020071611592878700_R309","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.ydbio.2006.12.011","article-title":"Ovarian granulosa cell survival and proliferation requires the gonad-selective TFIID subunit TAF4b.","volume":"303","author":"Voronina","year":"2007","journal-title":"Dev Biol"},{"key":"2020071611592878700_R310","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.ydbio.2005.09.038","article-title":"TAF4b, a TBP associated factor, is required for oocyte development and function.","volume":"288","author":"Falender","year":"2005","journal-title":"Dev Biol"},{"key":"2020071611592878700_R311","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1073\/pnas.0510764103","article-title":"Cell-type-selective induction of c-jun by TAF4b directs ovarian-specific transcription networks.","volume":"103","author":"Geles","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R312","doi-asserted-by":"crossref","first-page":"33718","DOI":"10.1074\/jbc.M003555200","article-title":"Regulation of AP1 (Jun\/Fos) factor expression and activation in ovarian granulosa cells. Relation of JunD and Fra2 to terminal differentiation.","volume":"275","author":"Sharma","year":"2000","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R313","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/jcb.20577","article-title":"Cyclic AMP-dependent modification of gonad-selective TAF(II)105 in a human ovarian granulosa cell line.","volume":"96","author":"Wu","year":"2005","journal-title":"J Cell Biochem"},{"key":"2020071611592878700_R314","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.mce.2007.08.004","article-title":"The TATA binding protein associated factor 4b (TAF4b) mediates FSH stimulation of the IGFBP-3 promoter in cultured porcine ovarian granulosa cells.","volume":"278","author":"Ongeri","year":"2007","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R315","doi-asserted-by":"crossref","first-page":"11209","DOI":"10.1073\/pnas.0404372101","article-title":"Subfertility and defective folliculogenesis in female mice lacking androgen receptor.","volume":"101","author":"Hu","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R316","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1073\/pnas.0506736102","article-title":"Premature ovarian failure in androgen receptor-deficient mice.","volume":"103","author":"Shiina","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R317","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1210\/jcem.84.8.5929","article-title":"Androgen and follicle-stimulating hormone interactions in primate ovarian follicle development.","volume":"84","author":"Weil","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R318","doi-asserted-by":"crossref","first-page":"17294","DOI":"10.1073\/pnas.0404743101","article-title":"Targeted disruption of luteinizing hormone \u03b2-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility.","volume":"101","author":"Ma","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R319","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1210\/mend.15.1.0586","article-title":"Targeted disruption of luteinizing hormone\/human chorionic gonadotropin receptor gene.","volume":"15","author":"Lei","year":"2001","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R320","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1210\/mend.15.1.0582","article-title":"Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice.","volume":"15","author":"Zhang","year":"2001","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R321","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1210\/endo.143.6.8845","article-title":"Mitogen-activated protein kinase activity in cumulus cells is essential for gonadotropin-induced oocyte meiotic resumption and cumulus expansion in the mouse.","volume":"143","author":"Su","year":"2002","journal-title":"Endocrinology"},{"key":"2020071611592878700_R322","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1126\/science.1171396","article-title":"MAPK3\/1 (ERK1\/2) in ovarian granulosa cells are essential for female fertility.","volume":"324","author":"Fan","year":"2009","journal-title":"Science"},{"key":"2020071611592878700_R323","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/0012-1606(90)90172-F","article-title":"FSH-induced expansion of the mouse cumulus oophorus in vitro is dependent upon a specific factor (s) secreted by the oocyte.","volume":"138","author":"Buccione","year":"1990","journal-title":"Dev Biol"},{"key":"2020071611592878700_R324","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.mce.2005.01.004","article-title":"Ovulation: new factors that prepare the oocyte for fertilization.","volume":"234","author":"Richards","year":"2005","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R325","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1210\/me.2005-0420","article-title":"Gene expression profiles of cumulus cell oocyte complexes during ovulation reveal cumulus cells express neuronal and immune-related genes: does this expand their role in the ovulation process?","volume":"20","author":"Hernandez-Gonzalez","year":"2006","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R326","doi-asserted-by":"crossref","first-page":"11119","DOI":"10.1074\/jbc.M313471200","article-title":"Specificity of the tumor necrosis factor-induced protein 6-mediated heavy chain transfer from inter-\u03b1-trypsin inhibitor to hyaluronan: implications for the assembly of the cumulus extracellular matrix.","volume":"279","author":"Mukhopadhyay","year":"2004","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R327","doi-asserted-by":"crossref","first-page":"30161","DOI":"10.1074\/jbc.M703738200","article-title":"PTX3 interacts with inter-\u03b1-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansion.","volume":"282","author":"Scarchilli","year":"2007","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R328","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1210\/en.2002-220435","article-title":"Decreased expression of tumor necrosis factor-\u03b1-stimulated gene 6 in cumulus cells of the cyclooxygenase-2 and EP2 null mice.","volume":"144","author":"Ochsner","year":"2003","journal-title":"Endocrinology"},{"key":"2020071611592878700_R329","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/378406a0","article-title":"Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.","volume":"378","author":"Dinchuk","year":"1995","journal-title":"Nature"},{"key":"2020071611592878700_R330","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0092-8674(00)80402-X","article-title":"Multiple female reproductive failures in cyclooxygenase 2-deficient mice.","volume":"91","author":"Lim","year":"1997","journal-title":"Cell"},{"key":"2020071611592878700_R331","doi-asserted-by":"crossref","first-page":"10501","DOI":"10.1073\/pnas.96.18.10501","article-title":"Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2).","volume":"96","author":"Hizaki","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R332","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/5583","article-title":"Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor.","volume":"5","author":"Kennedy","year":"1999","journal-title":"Nat Med"},{"key":"2020071611592878700_R333","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1172\/JCI6579","article-title":"Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor.","volume":"103","author":"Tilley","year":"1999","journal-title":"J Clin Invest"},{"key":"2020071611592878700_R334","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1242\/dev.00422","article-title":"Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice.","volume":"130","author":"F\u00fcl\u00f6p","year":"2003","journal-title":"Development"},{"key":"2020071611592878700_R335","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1172\/JCI10272","article-title":"Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme.","volume":"106","author":"Camenisch","year":"2000","journal-title":"J Clin Invest"},{"key":"2020071611592878700_R336","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/mrd.20971","article-title":"Targeted suppression of Has2 mRNA in mouse cumulus cell-oocyte complexes by adenovirus-mediated short-hairpin RNA expression.","volume":"76","author":"Sugiura","year":"2009","journal-title":"Mol Reprod Dev"},{"key":"2020071611592878700_R337","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1006\/bbrc.2001.4475","article-title":"Impaired fertility in female mice lacking urinary trypsin inhibitor.","volume":"281","author":"Sato","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"2020071611592878700_R338","doi-asserted-by":"crossref","first-page":"7693","DOI":"10.1074\/jbc.C000899200","article-title":"Defect in SHAP-hyaluronan complex causes severe female infertility. A study by inactivation of the bikunin gene in mice.","volume":"276","author":"Zhuo","year":"2001","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R339","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1210\/en.2002-220434","article-title":"Hormone-regulated expression and localization of versican in the rodent ovary.","volume":"144","author":"Russell","year":"2003","journal-title":"Endocrinology"},{"key":"2020071611592878700_R340","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1006\/dbio.1998.9001","article-title":"The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation.","volume":"202","author":"Mjaatvedt","year":"1998","journal-title":"Dev Biol"},{"key":"2020071611592878700_R341","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1172\/JCI8635","article-title":"ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.","volume":"105","author":"Shindo","year":"2000","journal-title":"J Clin Invest"},{"key":"2020071611592878700_R342","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1095\/biolreprod.103.023911","article-title":"Adamts-1 is essential for the development and function of the urogenital system.","volume":"70","author":"Mittaz","year":"2004","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R343","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.1210\/endo-129-6-3200","article-title":"Localization of luteinizing hormone receptor messenger ribonucleic acid expression in ovarian cell types during follicle development and ovulation.","volume":"129","author":"Peng","year":"1991","journal-title":"Endocrinology"},{"key":"2020071611592878700_R344","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1126\/science.1092463","article-title":"EGF-like growth factors as mediators of LH action in the ovulatory follicle.","volume":"303","author":"Park","year":"2004","journal-title":"Science"},{"key":"2020071611592878700_R345","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1128\/MCB.01919-06","article-title":"Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation.","volume":"27","author":"Hsieh","year":"2007","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R346","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1055\/s-0028-1108010","article-title":"Epidermal growth factor-like growth factors in the follicular fluid: role in oocyte development and maturation.","volume":"27","author":"Hsieh","year":"2009","journal-title":"Semin Reprod Med"},{"key":"2020071611592878700_R347","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.fertnstert.2008.01.014","article-title":"Amphiregulin is much more abundantly expressed than transforming growth factor-\u03b1 and epidermal growth factor in human follicular fluid obtained from patients undergoing in vitro fertilization-embryo transfer.","volume":"91","author":"Inoue","year":"2009","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R348","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1096\/fj.06-7688com","article-title":"Low expression of COX-2, reduced cumulus expansion, and impaired ovulation in SULT1E1-deficient mice.","volume":"21","author":"Gershon","year":"2007","journal-title":"FASEB J"},{"key":"2020071611592878700_R349","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1210\/me.2009-0030","article-title":"ERK signaling in the pituitary is required for female but not male fertility.","volume":"23","author":"Bliss","year":"2009","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R350","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0012-1606(90)90173-G","article-title":"Mouse oocytes regulate hyaluronic acid synthesis and mucification by FSH-stimulated cumulus cells.","volume":"138","author":"Salustri","year":"1990","journal-title":"Dev Biol"},{"key":"2020071611592878700_R351","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1095\/biolreprod.104.033357","article-title":"RNA interference evidence that growth differentiation factor-9 mediates oocyte regulation of cumulus expansion in mice.","volume":"72","author":"Gui","year":"2005","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R352","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/humupd\/dml014","article-title":"Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein\/growth differentiation factor ligands.","volume":"12","author":"Mazerbourg","year":"2006","journal-title":"Hum Reprod Update"},{"key":"2020071611592878700_R353","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1095\/biolreprod.106.057471","article-title":"Oocyte-secreted factor activation of SMAD 2\/3 signaling enables initiation of mouse cumulus cell expansion.","volume":"76","author":"Dragovic","year":"2007","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R354","doi-asserted-by":"crossref","first-page":"7001","DOI":"10.1128\/MCB.00732-08","article-title":"Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo.","volume":"28","author":"Li","year":"2008","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R355","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1095\/biolreprod.105.042127","article-title":"The art and artifact of GDF9 activity: cumulus expansion and the cumulus expansion-enabling factor.","volume":"73","author":"Pangas","year":"2005","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R356","doi-asserted-by":"crossref","first-page":"10678","DOI":"10.1073\/pnas.0600507103","article-title":"A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse.","volume":"103","author":"Yoshino","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R357","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ydbio.2004.08.020","article-title":"Synergistic roles of BMP15 and GDF9 in the development and function of the oocyte-cumulus cell complex in mice: genetic evidence for an oocyte-granulosa cell regulatory loop.","volume":"276","author":"Su","year":"2004","journal-title":"Dev Biol"},{"key":"2020071611592878700_R358","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1074\/jbc.M207362200","article-title":"Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells.","volume":"278","author":"Moore","year":"2003","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R359","doi-asserted-by":"crossref","first-page":"7994","DOI":"10.1073\/pnas.141002798","article-title":"The type I BMP receptor BmprIB is essential for female reproductive function.","volume":"98","author":"Yi","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R360","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/humrep\/dem029","article-title":"High bone morphogenetic protein-15 level in follicular fluid is associated with high quality oocyte and subsequent embryonic development.","volume":"22","author":"Wu","year":"2007","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R361","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1093\/humrep\/deh535","article-title":"Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF.","volume":"19","author":"McKenzie","year":"2004","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R362","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1530\/REP-07-0182","article-title":"Association between human oocyte developmental competence and expression levels of some cumulus genes.","volume":"134","author":"Cillo","year":"2007","journal-title":"Reproduction"},{"key":"2020071611592878700_R363","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1093\/humrep\/del065","article-title":"The human cumulus\u2013oocyte complex gene-expression profile.","volume":"21","author":"Assou","year":"2006","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R364","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.tem.2008.03.001","article-title":"Immune-like mechanisms in ovulation.","volume":"19","author":"Richards","year":"2008","journal-title":"Trends Endocrinol Metab"},{"key":"2020071611592878700_R365","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1210\/endo.133.2.8344215","article-title":"Hormonal regulation, localization, and functional activity of the progesterone receptor in granulosa cells of rat preovulatory follicles.","volume":"133","author":"Natraj","year":"1993","journal-title":"Endocrinology"},{"key":"2020071611592878700_R366","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1210\/mend-5-7-967","article-title":"Transient expression of progesterone receptor messenger RNA in ovarian granulosa cells after the preovulatory luteinizing hormone surge.","volume":"5","author":"Park","year":"1991","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R367","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1530\/rep.1.00189","article-title":"Reproductive tissue selective actions of progesterone receptors.","volume":"128","author":"Mulac-Jericevic","year":"2004","journal-title":"Reproduction"},{"key":"2020071611592878700_R368","doi-asserted-by":"crossref","first-page":"4689","DOI":"10.1073\/pnas.080073497","article-title":"Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases.","volume":"97","author":"Robker","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R369","doi-asserted-by":"crossref","first-page":"9744","DOI":"10.1073\/pnas.1732707100","article-title":"Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform.","volume":"100","author":"Mulac-Jericevic","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R370","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1126\/science.289.5485.1751","article-title":"Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform.","volume":"289","author":"Mulac-Jericevic","year":"2000","journal-title":"Science"},{"key":"2020071611592878700_R371","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1055\/s-2007-980217","article-title":"Genetics of ovulation.","volume":"25","author":"Richards","year":"2007","journal-title":"Semin Reprod Med"},{"key":"2020071611592878700_R372","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.physiol.64.081501.131029","article-title":"Ovulation: new dimensions and new regulators of the inflammatory-like response.","volume":"64","author":"Richards","year":"2002","journal-title":"Annu Rev Physiol"},{"key":"2020071611592878700_R373","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1210\/me.2006-0093","article-title":"A novel pathway involving progesterone receptor, endothelin-2, and endothelin receptor B controls ovulation in mice.","volume":"20","author":"Palanisamy","year":"2006","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R374","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1210\/en.2005-1228","article-title":"Endothelin-2 in ovarian follicle rupture.","volume":"147","author":"Ko","year":"2006","journal-title":"Endocrinology"},{"key":"2020071611592878700_R375","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1210\/me.2005-0317","article-title":"Cyclic guanosine 5\u2032-monophosphate-dependent protein kinase II is induced by luteinizing hormone and progesterone receptor-dependent mechanisms in granulosa cells and cumulus oocyte complexes of ovulating follicles.","volume":"20","author":"Sriraman","year":"2006","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R376","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/gene.20098","article-title":"Cre-mediated recombination in cell lineages that express the progesterone receptor.","volume":"41","author":"Soyal","year":"2005","journal-title":"Genesis"},{"key":"2020071611592878700_R377","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1128\/MCB.01556-07","article-title":"Peroxisome proliferator-activated receptor \u03b3 is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice.","volume":"28","author":"Kim","year":"2008","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R378","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1210\/me.2007-0042","article-title":"Synaptosomal-associated protein 25 gene expression is hormonally regulated during ovulation and is involved in cytokine\/chemokine exocytosis from granulosa cells.","volume":"21","author":"Shimada","year":"2007","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R379","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1101\/gad.11.17.2153","article-title":"An essential role for C\/EBP\u03b2 in female reproduction.","volume":"11","author":"Sterneck","year":"1997","journal-title":"Genes Dev"},{"key":"2020071611592878700_R380","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1210\/en.2004-0842","article-title":"Repression of the inhibin \u03b1-subunit gene by the transcription factor CCAAT\/enhancer-binding protein-\u03b2.","volume":"146","author":"Burkart","year":"2005","journal-title":"Endocrinology"},{"key":"2020071611592878700_R381","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1101\/gad.472008","article-title":"Liver receptor homolog 1 is essential for ovulation.","volume":"22","author":"Duggavathi","year":"2008","journal-title":"Genes Dev"},{"key":"2020071611592878700_R382","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1095\/biolreprod.108.069435","article-title":"Impaired follicle development and infertility in female mice lacking steroidogenic factor 1 in ovarian granulosa cells.","volume":"79","author":"Pelusi","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R383","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0960-0760(96)00008-8","article-title":"Nitric oxide inhibits aromatase activity: mechanisms of action.","volume":"58","author":"Snyder","year":"1996","journal-title":"J Steroid Biochem Mol Biol"},{"key":"2020071611592878700_R384","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1093\/molehr\/5.5.396","article-title":"Inhibitory effects of nitric oxide on the expression and activity of aromatase in human granulosa cells.","volume":"5","author":"Kagabu","year":"1999","journal-title":"Mol Hum Reprod"},{"key":"2020071611592878700_R385","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1038\/82183","article-title":"The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility.","volume":"6","author":"White","year":"2000","journal-title":"Nat Med"},{"key":"2020071611592878700_R386","doi-asserted-by":"crossref","first-page":"15058","DOI":"10.1073\/pnas.0405700101","article-title":"Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4.","volume":"101","author":"Collins","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R387","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1210\/me.2007-0181","article-title":"Subfertility with defective folliculogenesis in female mice lacking testicular orphan nuclear receptor 4.","volume":"22","author":"Chen","year":"2008","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R388","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1210\/er.2006-0022","article-title":"The molecular control of corpus luteum formation, function, and regression.","volume":"28","author":"Stocco","year":"2007","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R389","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.fertnstert.2008.07.1745","article-title":"The human corpus luteum: life cycle and function in natural cycles.","volume":"92","author":"Devoto","year":"2009","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R390","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1210\/mend.12.7.0138","article-title":"Hormone-induced proliferation and differentiation of granulosa cells: a coordinated balance of the cell cycle regulators cyclin D2 and p27Kip1.","volume":"12","author":"Robker","year":"1998","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R391","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0092-8674(00)81239-8","article-title":"A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice.","volume":"85","author":"Fero","year":"1996","journal-title":"Cell"},{"key":"2020071611592878700_R392","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S0092-8674(00)81238-6","article-title":"Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).","volume":"85","author":"Kiyokawa","year":"1996","journal-title":"Cell"},{"key":"2020071611592878700_R393","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0092-8674(00)81237-4","article-title":"Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.","volume":"85","author":"Nakayama","year":"1996","journal-title":"Cell"},{"key":"2020071611592878700_R394","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1038\/377552a0","article-title":"Radiation-induced cell cycle arrest compromised by p21 deficiency.","volume":"377","author":"Brugarolas","year":"1995","journal-title":"Nature"},{"key":"2020071611592878700_R395","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0092-8674(95)90039-X","article-title":"Mice lacking p21CIP1\/WAF1 undergo normal development, but are defective in G1 checkpoint control.","volume":"82","author":"Deng","year":"1995","journal-title":"Cell"},{"key":"2020071611592878700_R396","doi-asserted-by":"crossref","first-page":"17021","DOI":"10.1074\/jbc.M301206200","article-title":"The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells.","volume":"278","author":"Jirawatnotai","year":"2003","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R397","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/8751","article-title":"Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in \u03b2-islet cell hyperplasia.","volume":"22","author":"Rane","year":"1999","journal-title":"Nat Genet"},{"key":"2020071611592878700_R398","doi-asserted-by":"crossref","first-page":"7011","DOI":"10.1128\/MCB.19.10.7011","article-title":"Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.","volume":"19","author":"Tsutsui","year":"1999","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R399","doi-asserted-by":"crossref","first-page":"51100","DOI":"10.1074\/jbc.M409080200","article-title":"Cdk4 is indispensable for postnatal proliferation of the anterior pituitary.","volume":"279","author":"Jirawatnotai","year":"2004","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R400","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1210\/mend.13.12.0389","article-title":"Differentiation-dependent prolactin responsiveness and STAT (signal transducers and activators of transcription) signaling in rat ovarian cells.","volume":"13","author":"Russell","year":"1999","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R401","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1101\/gad.11.2.167","article-title":"Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.","volume":"11","author":"Ormandy","year":"1997","journal-title":"Genes Dev"},{"key":"2020071611592878700_R402","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1477-7827-1-12","article-title":"Effects of deletion of the prolactin receptor on ovarian gene expression.","volume":"1","author":"Grosdemouge","year":"2003","journal-title":"Reprod Biol Endocrinol"},{"key":"2020071611592878700_R403","doi-asserted-by":"crossref","first-page":"6926","DOI":"10.1093\/emboj\/16.23.6926","article-title":"Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene.","volume":"16","author":"Horseman","year":"1997","journal-title":"EMBO J"},{"key":"2020071611592878700_R404","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0092-8674(00)81444-0","article-title":"Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.","volume":"93","author":"Teglund","year":"1998","journal-title":"Cell"},{"key":"2020071611592878700_R405","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1095\/biolreprod.105.042739","article-title":"Mice null for Frizzled4 (Fzd4\u2212\/\u2212) are infertile and exhibit impaired corpora lutea formation and function.","volume":"73","author":"Hsieh","year":"2005","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R406","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1210\/me.2008-0095","article-title":"Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells.","volume":"22","author":"Fan","year":"2008","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R407","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.ydbio.2007.02.019","article-title":"Oocytes are required for the preantral granulosa cell to cumulus cell transition in mice.","volume":"305","author":"Diaz","year":"2007","journal-title":"Dev Biol"},{"key":"2020071611592878700_R408","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1210\/me.2005-0462","article-title":"Premature luteinization and cumulus cell defects in ovarian-specific Smad4 knockout mice.","volume":"20","author":"Pangas","year":"2006","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R409","author":"Eppig","year":"2004"},{"key":"2020071611592878700_R410","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1530\/rep.1.00793","article-title":"Stops and starts in mammalian oocytes: recent advances in understanding the regulation of meiotic arrest and oocyte maturation.","volume":"130","author":"Mehlmann","year":"2005","journal-title":"Reproduction"},{"key":"2020071611592878700_R411","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/208349a0","article-title":"Maturation in vitro of mouse, sheep, cow, pig, rhesus monkey and human ovarian oocytes.","volume":"208","author":"Edwards","year":"1965","journal-title":"Nature"},{"key":"2020071611592878700_R412","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1084\/jem.62.5.665","article-title":"The comparative behavior of mammalian eggs in vivo and in vitro. I. The activation of ovarian eggs.","volume":"62","author":"Pincus","year":"1935","journal-title":"J Exp Med"},{"key":"2020071611592878700_R413","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.tibs.2005.09.005","article-title":"Mammalian cyclin-dependent kinases.","volume":"30","author":"Malumbres","year":"2005","journal-title":"Trends Biochem Sci"},{"key":"2020071611592878700_R414","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/j.cub.2005.07.056","article-title":"Wee1B is an oocyte-specific kinase involved in the control of meiotic arrest in the mouse.","volume":"15","author":"Han","year":"2005","journal-title":"Curr Biol"},{"key":"2020071611592878700_R415","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1172\/JCI21804","article-title":"Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility.","volume":"114","author":"Masciarelli","year":"2004","journal-title":"J Clin Invest"},{"key":"2020071611592878700_R416","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/dbio.1995.1207","article-title":"The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis.","volume":"170","author":"Wu","year":"1995","journal-title":"Dev Biol"},{"key":"2020071611592878700_R417","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/ng856","article-title":"Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation.","volume":"30","author":"Lincoln","year":"2002","journal-title":"Nat Genet"},{"key":"2020071611592878700_R418","doi-asserted-by":"crossref","first-page":"3853","DOI":"10.1128\/MCB.21.12.3853-3861.2001","article-title":"Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase.","volume":"21","author":"Chen","year":"2001","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R419","doi-asserted-by":"crossref","first-page":"6605","DOI":"10.1158\/0008-5472.CAN-06-4815","article-title":"Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice.","volume":"67","author":"Ray","year":"2007","journal-title":"Cancer Res"},{"key":"2020071611592878700_R420","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ydbio.2008.02.028","article-title":"CDC25A phosphatase controls meiosis I progression in mouse oocytes.","volume":"317","author":"Solc","year":"2008","journal-title":"Dev Biol"},{"key":"2020071611592878700_R421","doi-asserted-by":"crossref","first-page":"16794","DOI":"10.1073\/pnas.222661299","article-title":"G2 arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A.","volume":"99","author":"Duckworth","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R422","doi-asserted-by":"crossref","first-page":"665","DOI":"10.4161\/cc.8.4.7846","article-title":"Protein kinase A regulates resumption of meiosis by phosphorylation of Cdc25B in mammalian oocytes.","volume":"8","author":"Pirino","year":"2009","journal-title":"Cell Cycle"},{"key":"2020071611592878700_R423","doi-asserted-by":"crossref","first-page":"3777","DOI":"10.1002\/dvdy.21799","article-title":"Protein kinase A modulates Cdc25B activity during meiotic resumption of mouse oocytes.","volume":"237","author":"Zhang","year":"2008","journal-title":"Dev Dyn"},{"key":"2020071611592878700_R424","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/0012-1606(83)90085-4","article-title":"Regulation of mouse oocyte meiotic maturation: implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis.","volume":"97","author":"Schultz","year":"1983","journal-title":"Dev Biol"},{"key":"2020071611592878700_R425","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1210\/endo-113-3-1170","article-title":"Inhibition of denuded mouse oocyte meiotic maturation by forskolin, an activator of adenylate cyclase.","volume":"113","author":"Urner","year":"1983","journal-title":"Endocrinology"},{"key":"2020071611592878700_R426","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0045-6039(83)90023-4","article-title":"Meiotic resumption and intracellular cAMP levels in mouse oocytes treated with compounds which act on cAMP metabolism.","volume":"12","author":"Vivarelli","year":"1983","journal-title":"Cell Differ"},{"key":"2020071611592878700_R427","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1126\/science.1073978","article-title":"Meiotic arrest in the mouse follicle maintained by a Gs protein in the oocyte.","volume":"297","author":"Mehlmann","year":"2002","journal-title":"Science"},{"key":"2020071611592878700_R428","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1126\/science.1103974","article-title":"The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes.","volume":"306","author":"Mehlmann","year":"2004","journal-title":"Science"},{"key":"2020071611592878700_R429","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/S0898-6568(02)00041-4","article-title":"Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors.","volume":"14","author":"Uhlenbrock","year":"2002","journal-title":"Cell Signal"},{"key":"2020071611592878700_R430","doi-asserted-by":"crossref","first-page":"8922","DOI":"10.1073\/pnas.0503840102","article-title":"Premature ovarian aging in mice deficient for Gpr3.","volume":"102","author":"Ledent","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R431","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1083\/jcb.200506194","article-title":"Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein.","volume":"171","author":"Freudzon","year":"2005","journal-title":"J Cell Biol"},{"key":"2020071611592878700_R432","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0012-1606(03)00134-9","article-title":"Rodent oocytes express an active adenylyl cyclase required for meiotic arrest.","volume":"258","author":"Horner","year":"2003","journal-title":"Dev Biol"},{"key":"2020071611592878700_R433","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0896-6273(00)00060-X","article-title":"Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice.","volume":"27","author":"Wong","year":"2000","journal-title":"Neuron"},{"key":"2020071611592878700_R434","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1210\/mend-5-12-1947","article-title":"Inhibitors of phosphodiesterase III block stimulation of Xenopus laevis oocyte ribosomal S6 kinase activity by insulin-like growth factor-I.","volume":"5","author":"Sadler","year":"1991","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R435","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1095\/biolreprod65.1.188","article-title":"Cloning and characterization of the cyclic guanosine monophosphate-inhibited phosphodiesterase PDE3A expressed in mouse oocyte.","volume":"65","author":"Shitsukawa","year":"2001","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R436","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1095\/biolreprod65.5.1444","article-title":"Role of phosphodiesterase type 3A in rat oocyte maturation.","volume":"65","author":"Richard","year":"2001","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R437","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1095\/biolreprod.103.015982","article-title":"Human oocytes reversibly arrested in prophase I by phosphodiesterase type 3 inhibitor in vitro.","volume":"69","author":"Nogueira","year":"2003","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R438","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.cub.2005.12.031","article-title":"Dynamic anchoring of PKA is essential during oocyte maturation.","volume":"16","author":"Newhall","year":"2006","journal-title":"Curr Biol"},{"key":"2020071611592878700_R439","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1210\/en.2005-1011","article-title":"Disruption of gap junctional communication within the ovarian follicle induces oocyte maturation.","volume":"147","author":"Sela-Abramovich","year":"2006","journal-title":"Endocrinology"},{"key":"2020071611592878700_R440","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1242\/dev.025494","article-title":"Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption.","volume":"135","author":"Norris","year":"2008","journal-title":"Development"},{"key":"2020071611592878700_R441","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/jez.1402450113","article-title":"Induction of maturation in cumulus cell-enclosed mouse oocytes by follicle-stimulating hormone and epidermal growth factor: evidence for a positive stimulus of somatic cell origin.","volume":"245","author":"Downs","year":"1988","journal-title":"J Exp Zool"},{"key":"2020071611592878700_R442","doi-asserted-by":"crossref","first-page":"16257","DOI":"10.1073\/pnas.0508521102","article-title":"Epidermal growth factor receptor signaling is required for normal ovarian steroidogenesis and oocyte maturation.","volume":"102","author":"Jamnongjit","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R443","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0012-1606(83)90198-7","article-title":"Inhibition of oocyte maturation in the mouse: participation of cAMP, steroid hormones, and a putative maturation-inhibitory factor.","volume":"100","author":"Eppig","year":"1983","journal-title":"Dev Biol"},{"key":"2020071611592878700_R444","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/jez.1402430316","article-title":"Inhibition of mouse oocyte cyclic AMP phosphodiesterase by steroid hormones: a possible mechanism for steroid hormone inhibition of oocyte maturation.","volume":"243","author":"Kaji","year":"1987","journal-title":"J Exp Zool"},{"key":"2020071611592878700_R445","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/374559a0","article-title":"Chemical structure of sterols that activate oocyte meiosis.","volume":"374","author":"Byskov","year":"1995","journal-title":"Nature"},{"key":"2020071611592878700_R446","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/oxfordjournals.humrep.a137351","article-title":"Regulation of oocyte maturation by changes in ovarian levels of cyclic nucleotides.","volume":"6","author":"T\u00f6rnell","year":"1991","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R447","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1748-1716.1990.tb08953.x","article-title":"Resumption of rat oocyte meiosis is paralleled by a decrease in guanosine 3\u2032,5\u2032-cyclic monophosphate (cGMP) and is inhibited by microinjection of cGMP.","volume":"139","author":"T\u00f6rnell","year":"1990","journal-title":"Acta Physiol Scand"},{"key":"2020071611592878700_R448","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1095\/biolreprod.107.065490","article-title":"Inhibition of rat oocyte maturation and ovulation by nitric oxide: mechanism of action.","volume":"78","author":"Sela-Abramovich","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R449","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1095\/biolreprod.109.077768","article-title":"Cyclic GMP signaling is involved in the luteinizing hormone-dependent meiotic maturation of mouse oocytes.","volume":"81","author":"Vaccari","year":"2009","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R450","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/jez.1401770202","article-title":"Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes.","volume":"177","author":"Masui","year":"1971","journal-title":"J Exp Zool"},{"key":"2020071611592878700_R451","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/nrm1988","article-title":"The anaphase promoting complex\/cyclosome: a machine designed to destroy.","volume":"7","author":"Peters","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2020071611592878700_R452","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/342512a0","article-title":"The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs.","volume":"342","author":"Sagata","year":"1989","journal-title":"Nature"},{"key":"2020071611592878700_R453","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/370065a0","article-title":"Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs.","volume":"370","author":"Colledge","year":"1994","journal-title":"Nature"},{"key":"2020071611592878700_R454","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/370068a0","article-title":"Parthenogenetic activation of oocytes in c-mos-deficient mice.","volume":"370","author":"Hashimoto","year":"1994","journal-title":"Nature"},{"key":"2020071611592878700_R455","doi-asserted-by":"crossref","first-page":"7032","DOI":"10.1073\/pnas.93.14.7032","article-title":"The Mos\/mitogen-activated protein kinase (MAPK) pathway regulates the size and degradation of the first polar body in maturing mouse oocytes.","volume":"93","author":"Choi","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R456","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1101\/gad.320705","article-title":"Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC\/C activity.","volume":"19","author":"Schmidt","year":"2005","journal-title":"Genes Dev"},{"key":"2020071611592878700_R457","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/sj.emboj.7600953","article-title":"Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20.","volume":"25","author":"Shoji","year":"2006","journal-title":"EMBO J"},{"key":"2020071611592878700_R458","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1083\/jcb.200604140","article-title":"Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis.","volume":"174","author":"Madgwick","year":"2006","journal-title":"J Cell Biol"},{"key":"2020071611592878700_R459","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/embor.2008.22","article-title":"Second meiotic arrest and exit in frogs and mice.","volume":"9","author":"Perry","year":"2008","journal-title":"EMBO Rep"},{"key":"2020071611592878700_R460","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1126\/science.286.5443.1362","article-title":"The protein kinase p90 rsk as an essential mediator of cytostatic factor activity.","volume":"286","author":"Bhatt","year":"1999","journal-title":"Science"},{"key":"2020071611592878700_R461","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1126\/science.286.5443.1365","article-title":"Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90Rsk.","volume":"286","author":"Gross","year":"1999","journal-title":"Science"},{"key":"2020071611592878700_R462","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/nature05688","article-title":"A direct link of the Mos-MAPK pathway to Erp1\/Emi2 in meiotic arrest of Xenopus laevis eggs.","volume":"446","author":"Inoue","year":"2007","journal-title":"Nature"},{"key":"2020071611592878700_R463","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/nature05696","article-title":"Phosphorylation of Erp1 by p90rsk is required for cytostatic factor arrest in Xenopus laevis eggs.","volume":"446","author":"Nishiyama","year":"2007","journal-title":"Nature"},{"key":"2020071611592878700_R464","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1083\/jcb.200501027","article-title":"p90Rsk is not involved in cytostatic factor arrest in mouse oocytes.","volume":"169","author":"Dumont","year":"2005","journal-title":"J Cell Biol"},{"key":"2020071611592878700_R465","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1242\/dev.129.15.3533","article-title":"PLC \u03b6: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development.","volume":"129","author":"Saunders","year":"2002","journal-title":"Development"},{"key":"2020071611592878700_R466","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0960-9822(02)00811-4","article-title":"Ca(2+) oscillations promote APC\/C-dependent cyclin B1 degradation during metaphase arrest and completion of meiosis in fertilizing mouse eggs.","volume":"12","author":"Nixon","year":"2002","journal-title":"Curr Biol"},{"key":"2020071611592878700_R467","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3322\/CA.2007.0010","article-title":"Cancer statistics, 2008.","volume":"58","author":"Jemal","year":"2008","journal-title":"CA Cancer J Clin"},{"key":"2020071611592878700_R468","first-page":"1066","author":"Crum","year":"1999"},{"key":"2020071611592878700_R469","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/01.pgp.0000101080.35393.16","article-title":"The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin.","volume":"23","author":"Seidman","year":"2004","journal-title":"Int J Gynecol Pathol"},{"issue":"Suppl 2","key":"2020071611592878700_R470","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1038\/modpathol.3800306","article-title":"Origins and molecular pathology of ovarian cancer","volume":"18","author":"Bell","year":"2005","journal-title":"Mod Pathol"},{"key":"2020071611592878700_R471","first-page":"255","article-title":"Ovarian surface epithelium: biology, endocrinology, and pathology.","volume":"22","author":"Auersperg","year":"2001","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R472","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0140-6736(71)92335-X","article-title":"Incessant ovulation\u2014a factor in ovarian neoplasia?","volume":"2","author":"Fathalla","year":"1971","journal-title":"Lancet"},{"key":"2020071611592878700_R473","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1093\/jnci\/84.8.592","article-title":"Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer.","volume":"84","author":"Godwin","year":"1992","journal-title":"J Natl Cancer Inst"},{"key":"2020071611592878700_R474","first-page":"2778","article-title":"Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexity.","volume":"54","author":"Testa","year":"1994","journal-title":"Cancer Res"},{"key":"2020071611592878700_R475","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1046\/j.1365-2559.2001.01042.x","article-title":"Precursor lesions of ovarian epithelial malignancy.","volume":"38","author":"Feeley","year":"2001","journal-title":"Histopathology"},{"key":"2020071611592878700_R476","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1006\/gyno.1998.5275","article-title":"The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes?","volume":"72","author":"Dubeau","year":"1999","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R477","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S1470-2045(08)70308-5","article-title":"The cell of origin of ovarian epithelial tumours.","volume":"9","author":"Dubeau","year":"2008","journal-title":"Lancet Oncol"},{"key":"2020071611592878700_R478","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ygyno.2005.06.065","article-title":"Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers.","volume":"100","author":"Finch","year":"2006","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R479","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/01.pas.0000213335.40358.47","article-title":"Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.","volume":"31","author":"Kindelberger","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"2020071611592878700_R480","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3121\/cmr.2007.702","article-title":"Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer.","volume":"5","author":"Crum","year":"2007","journal-title":"Clin Med Res"},{"key":"2020071611592878700_R481","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.bpobgyn.2003.03.001","article-title":"Endometriosis and the development of malignant tumours of the pelvis. A review of literature.","volume":"18","author":"Van Gorp","year":"2004","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2020071611592878700_R482","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.ygyno.2005.11.033","article-title":"Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence.","volume":"101","author":"Somigliana","year":"2006","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R483","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1016\/j.fertnstert.2008.08.007","article-title":"The relationship of endometriosis and ovarian malignancy: a review.","volume":"90","author":"Nezhat","year":"2008","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R484","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1146\/annurev.pathol.4.110807.092246","article-title":"Ovarian cancer.","volume":"4","author":"Cho","year":"2009","journal-title":"Annu Rev Pathol"},{"key":"2020071611592878700_R485","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1158\/1541-7786.MCR-08-0193","article-title":"Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.","volume":"6","author":"Anglesio","year":"2008","journal-title":"Mol Cancer Res"},{"key":"2020071611592878700_R486","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S0002-9440(10)63708-X","article-title":"Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis.","volume":"164","author":"Shih IeM, Kurman","year":"2004","journal-title":"Am J Pathol"},{"key":"2020071611592878700_R487","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/01.pas.0000146025.91953.8d","article-title":"Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation.","volume":"29","author":"Singer","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"2020071611592878700_R488","first-page":"151","article-title":"Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications.","volume":"27","author":"Kurman","year":"2008","journal-title":"Int J Gynecol Pathol"},{"key":"2020071611592878700_R489","first-page":"2063","article-title":"Transformation of cultured rat ovarian surface epithelial cells by Kirsten murine sarcoma virus.","volume":"41","author":"Adams","year":"1981","journal-title":"Cancer Res"},{"key":"2020071611592878700_R490","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/carcin\/21.4.585","article-title":"Development of a syngeneic mouse model for events related to ovarian cancer.","volume":"21","author":"Roby","year":"2000","journal-title":"Carcinogenesis"},{"key":"2020071611592878700_R491","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nrc795","article-title":"Modelling the molecular circuitry of cancer.","volume":"2","author":"Hahn","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"2020071611592878700_R492","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0002-9378(11)91579-8","article-title":"Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix.","volume":"167","author":"Maines-Bandiera","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"2020071611592878700_R493","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1290\/1071-2690(2001)037<0515:DAGPOH>2.0.CO;2","article-title":"Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen.","volume":"37","author":"Leung","year":"2001","journal-title":"In Vitro Cell Dev Biol Anim"},{"key":"2020071611592878700_R494","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1006\/gyno.2000.6084","article-title":"Characterization and tumorigenicity of human ovarian surface epithelial cells immortalized by SV40 large T antigen.","volume":"81","author":"Nitta","year":"2001","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R495","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/S0014-4827(03)00218-0","article-title":"Immortalisation of human ovarian surface epithelium with telomerase and temperature-sensitive SV40 large T antigen.","volume":"288","author":"Davies","year":"2003","journal-title":"Exp Cell Res"},{"key":"2020071611592878700_R496","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1158\/0008-5472.CAN-03-3380","article-title":"A genetically defined model for human ovarian cancer.","volume":"64","author":"Liu","year":"2004","journal-title":"Cancer Res"},{"key":"2020071611592878700_R497","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/(SICI)1097-0215(20000201)85:3<430::AID-IJC21>3.0.CO;2-Q","article-title":"An ovarian adenocarcinoma line derived from SV40\/E-cadherin-transfected normal human ovarian surface epithelium.","volume":"85","author":"Ong","year":"2000","journal-title":"Int J Cancer"},{"key":"2020071611592878700_R498","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1038\/sj.bjc.6601423","article-title":"C-erbB-2 or mutant Ha-ras induced malignant transformation of immortalized human ovarian surface epithelial cells in vitro.","volume":"89","author":"Kusakari","year":"2003","journal-title":"Br J Cancer"},{"key":"2020071611592878700_R499","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1006\/excr.1995.1184","article-title":"Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs).","volume":"218","author":"Tsao","year":"1995","journal-title":"Exp Cell Res"},{"key":"2020071611592878700_R500","first-page":"4280","article-title":"Spontaneous malignant transformation of human ovarian surface epithelial cells in vitro.","volume":"7","author":"Gregoire","year":"2001","journal-title":"Clin Cancer Res"},{"key":"2020071611592878700_R501","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/path.1697","article-title":"Advances in imaging mouse tumour models in vivo.","volume":"205","author":"Lyons","year":"2005","journal-title":"J Pathol"},{"key":"2020071611592878700_R502","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.ymthe.2004.08.013","article-title":"Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer.","volume":"10","author":"Shaw","year":"2004","journal-title":"Mol Ther"},{"key":"2020071611592878700_R503","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S1535-6108(01)00002-2","article-title":"Induction of ovarian cancer by defined multiple genetic changes in a mouse model system.","volume":"1","author":"Orsulic","year":"2002","journal-title":"Cancer Cell"},{"key":"2020071611592878700_R504","first-page":"1389","article-title":"Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.","volume":"63","author":"Connolly","year":"2003","journal-title":"Cancer Res"},{"key":"2020071611592878700_R505","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1210\/me.2003-0404","article-title":"Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function.","volume":"18","author":"Jeyasuria","year":"2004","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R506","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ydbio.2007.04.036","article-title":"Essential roles of mesenchyme-derived \u03b2-catenin in mouse Mullerian duct morphogenesis.","volume":"307","author":"Deutscher","year":"2007","journal-title":"Dev Biol"},{"key":"2020071611592878700_R507","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1002\/mrd.20858","article-title":"A mesenchymal perspective of Mullerian duct differentiation and regression in Amhr2-lacZ mice.","volume":"75","author":"Arango","year":"2008","journal-title":"Mol Reprod Dev"},{"key":"2020071611592878700_R508","first-page":"3488","article-title":"Human ovarian cancer, cell lines, and primary ascites cells express the human Mullerian inhibiting substance (MIS) type II receptor, bind, and are responsive to MIS.","volume":"5","author":"Masiakos","year":"1999","journal-title":"Clin Cancer Res"},{"key":"2020071611592878700_R509","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.mce.2005.03.019","article-title":"Models of ovarian cancer\u2013are we there yet?","volume":"239","author":"Garson","year":"2005","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R510","first-page":"3459","article-title":"Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.","volume":"63","author":"Flesken-Nikitin","year":"2003","journal-title":"Cancer Res"},{"key":"2020071611592878700_R511","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/nm1173","article-title":"Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer.","volume":"11","author":"Dinulescu","year":"2005","journal-title":"Nat Med"},{"key":"2020071611592878700_R512","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/nm0105-24","article-title":"Gynecologic diseases get their genes.","volume":"11","author":"Matzuk","year":"2005","journal-title":"Nat Med"},{"key":"2020071611592878700_R513","doi-asserted-by":"crossref","first-page":"6463","DOI":"10.1158\/0008-5472.CAN-08-3363","article-title":"Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells.","volume":"69","author":"Fan","year":"2009","journal-title":"Cancer Res"},{"key":"2020071611592878700_R514","first-page":"7052","article-title":"Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary.","volume":"60","author":"Sato","year":"2000","journal-title":"Cancer Res"},{"key":"2020071611592878700_R515","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ccr.2007.02.016","article-title":"Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt\/\u03b2-catenin and PI3K\/Pten signaling pathways.","volume":"11","author":"Wu","year":"2007","journal-title":"Cancer Cell"},{"key":"2020071611592878700_R516","doi-asserted-by":"crossref","first-page":"11221","DOI":"10.1074\/jbc.M611871200","article-title":"Phosphorylation of \u03b2-catenin by AKT promotes \u03b2-catenin transcriptional activity.","volume":"282","author":"Fang","year":"2007","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R517","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.critrevonc.2008.06.003","article-title":"Hereditary ovarian cancer.","volume":"69","author":"Russo","year":"2009","journal-title":"Crit Rev Oncol Hematol"},{"key":"2020071611592878700_R518","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1126\/science.1088759","article-title":"Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2.","volume":"302","author":"King","year":"2003","journal-title":"Science"},{"key":"2020071611592878700_R519","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1200\/JCO.2007.11.3902","article-title":"Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway.","volume":"26","author":"Weberpals","year":"2008","journal-title":"J Clin Oncol"},{"key":"2020071611592878700_R520","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1093\/jnci\/88.24.1810","article-title":"Microscopic benign and invasive malignant neoplasms and a cancer-prone phenotype in prophylactic oophorectomies.","volume":"88","author":"Salazar","year":"1996","journal-title":"J Natl Cancer Inst"},{"key":"2020071611592878700_R521","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0046-8177(99)90269-1","article-title":"Altered surface and cyst epithelium of ovaries removed prophylactically from women with a family history of ovarian cancer.","volume":"30","author":"Werness","year":"1999","journal-title":"Hum Pathol"},{"key":"2020071611592878700_R522","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1002\/cncr.11848","article-title":"Prophylactic oophorectomy: a morphologic and immunohistochemical study.","volume":"98","author":"Schlosshauer","year":"2003","journal-title":"Cancer"},{"key":"2020071611592878700_R523","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.yexcr.2006.09.026","article-title":"Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.","volume":"313","author":"Clark-Knowles","year":"2007","journal-title":"Exp Cell Res"},{"key":"2020071611592878700_R524","doi-asserted-by":"crossref","first-page":"8949","DOI":"10.1158\/0008-5472.CAN-06-1495","article-title":"A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.","volume":"66","author":"Xing","year":"2006","journal-title":"Cancer Res"},{"key":"2020071611592878700_R525","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/(SICI)1098-2264(199906)25:2<91::AID-GCC3>3.0.CO;2-5","article-title":"Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours.","volume":"25","author":"Ramus","year":"1999","journal-title":"Genes Chromosomes Cancer"},{"key":"2020071611592878700_R526","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1093\/jnci\/92.13.1088","article-title":"Ovarian carcinoma in situ with germline BRCA1 mutation and loss of heterozygosity at BRCA1 and TP53.","volume":"92","author":"Werness","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"2020071611592878700_R527","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1158\/1078-0432.CCR-0976-03","article-title":"MYC is amplified in BRCA1-associated breast cancers.","volume":"10","author":"Grushko","year":"2004","journal-title":"Clin Cancer Res"},{"key":"2020071611592878700_R528","first-page":"3193","article-title":"Molecular genetic characterization of BRCA1- and BRCA2-linked hereditary ovarian cancers.","volume":"58","author":"Rhei","year":"1998","journal-title":"Cancer Res"},{"key":"2020071611592878700_R529","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1200\/JCO.2007.11.1005","article-title":"Management of ovarian stromal cell tumors.","volume":"25","author":"Colombo","year":"2007","journal-title":"J Clin Oncol"},{"key":"2020071611592878700_R530","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S1701-2163(16)30464-9","article-title":"Granulosa cell tumour: a recurrence 40 years after initial diagnosis.","volume":"27","author":"East","year":"2005","journal-title":"J Obstet Gynaecol Can"},{"key":"2020071611592878700_R531","first-page":"5575","article-title":"Spontaneous malignant granulosa cell tumors in ovaries of young SWR mice.","volume":"45","author":"Beamer","year":"1985","journal-title":"Cancer Res"},{"key":"2020071611592878700_R532","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1158\/0008-5472.CAN-04-2992","article-title":"Distal Chr 4 harbors a genetic locus (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model.","volume":"65","author":"Dorward","year":"2005","journal-title":"Cancer Res"},{"key":"2020071611592878700_R533","first-page":"5092","article-title":"Gene for ovarian granulosa cell tumor susceptibility, Gct, in SWXJ recombinant inbred strains of mice revealed by dehydroepiandrosterone.","volume":"48","author":"Beamer","year":"1988","journal-title":"Cancer Res"},{"key":"2020071611592878700_R534","first-page":"1059","article-title":"Genetic susceptibility for C19 androgen induction of ovarian granulosa cell tumorigenesis in SWXJ strains of mice.","volume":"53","author":"Tennent","year":"1993","journal-title":"Cancer Res"},{"key":"2020071611592878700_R535","first-page":"3694","article-title":"Multigenic and imprinting control of ovarian granulosa cell tumorigenesis in mice.","volume":"58","author":"Beamer","year":"1998","journal-title":"Cancer Res"},{"key":"2020071611592878700_R536","first-page":"8197","article-title":"High-resolution genetic map of X-linked juvenile-type granulosa cell tumor susceptibility genes in mouse.","volume":"63","author":"Dorward","year":"2003","journal-title":"Cancer Res"},{"key":"2020071611592878700_R537","first-page":"1589","article-title":"Genetic determinants of malignancy in a mouse model for oligodendroglioma.","volume":"63","author":"Weiss","year":"2003","journal-title":"Cancer Res"},{"key":"2020071611592878700_R538","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1038\/sj.onc.1205146","article-title":"Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2\/neu define mouse mammary gland adenocarcinomas induced by mutant HER2\/neu.","volume":"21","author":"Montagna","year":"2002","journal-title":"Oncogene"},{"key":"2020071611592878700_R539","first-page":"7048","article-title":"Sporadic and familial pheochromocytomas are associated with loss of at least two discrete intervals on chromosome 1p.","volume":"60","author":"Benn","year":"2000","journal-title":"Cancer Res"},{"key":"2020071611592878700_R540","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0165-4608(02)00653-2","article-title":"A consistent region of deletion on 1p36 in meningiomas: identification and relation to malignant progression.","volume":"140","author":"Murakami","year":"2003","journal-title":"Cancer Genet Cytogenet"},{"key":"2020071611592878700_R541","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S0165-4608(02)00740-9","article-title":"Detection by fluorescence in situ hybridization of microdeletions at 1p36 in lymphomas, unidentified on cytogenetic analysis.","volume":"142","author":"Rajgopal","year":"2003","journal-title":"Cancer Genet Cytogenet"},{"key":"2020071611592878700_R542","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/360313a0","article-title":"\u03b1-Inhibin is a tumour-suppressor gene with gonadal specificity in mice.","volume":"360","author":"Matzuk","year":"1992","journal-title":"Nature"},{"key":"2020071611592878700_R543","first-page":"123","article-title":"Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development.","volume":"51","author":"Matzuk","year":"1996","journal-title":"Recent Prog Horm Res"},{"key":"2020071611592878700_R544","doi-asserted-by":"crossref","first-page":"8817","DOI":"10.1073\/pnas.91.19.8817","article-title":"Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice.","volume":"91","author":"Matzuk","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R545","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1210\/endo.137.10.8828479","article-title":"Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice.","volume":"137","author":"Kumar","year":"1996","journal-title":"Endocrinology"},{"key":"2020071611592878700_R546","first-page":"3741","article-title":"Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors.","volume":"53","author":"Beamer","year":"1993","journal-title":"Cancer Res"},{"key":"2020071611592878700_R547","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1677\/erc.1.01232","article-title":"LH analog and dietary isoflavones support ovarian granulosa cell tumor development in a spontaneous mouse model.","volume":"14","author":"Dorward","year":"2007","journal-title":"Endocr Relat Cancer"},{"key":"2020071611592878700_R548","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1210\/er.2006-0036","article-title":"Gonadotropins and ovarian cancer.","volume":"28","author":"Choi","year":"2007","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R549","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1210\/mend.13.6.0297","article-title":"Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis.","volume":"13","author":"Kumar","year":"1999","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R550","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1073\/pnas.92.5.1322","article-title":"Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.","volume":"92","author":"Risma","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R551","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1073\/pnas.97.1.383","article-title":"Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition.","volume":"97","author":"Keri","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R552","first-page":"616","article-title":"Gonadal tumorigenesis in transgenic mice bearing the mouse inhibin \u03b1-subunit promoter\/simian virus T-antigen fusion gene: characterization of ovarian tumors and establishment of gonadotropin-responsive granulosa cell lines.","volume":"9","author":"Kananen","year":"1995","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R553","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1038\/sj.onc.1206518","article-title":"High levels of luteinizing hormone analog stimulate gonadal and adrenal tumorigenesis in mice transgenic for the mouse inhibin-\u03b1-subunit promoter\/Simian virus 40 T-antigen fusion gene.","volume":"22","author":"Mikola","year":"2003","journal-title":"Oncogene"},{"key":"2020071611592878700_R554","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1095\/biolreprod.102.013953","article-title":"Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.","volume":"69","author":"Matzuk","year":"2003","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R555","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.mce.2008.06.019","article-title":"Luteinizing hormone promotes gonadal tumorigenesis in inhibin-deficient mice.","volume":"294","author":"Nagaraja","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"2020071611592878700_R556","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/gcc.10108","article-title":"Evidence of a role for the INK4 family of cyclin-dependent kinase inhibitors in ovarian granulosa cell tumors.","volume":"35","author":"Arcellana-Panlilio","year":"2002","journal-title":"Genes Chromosomes Cancer"},{"key":"2020071611592878700_R557","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1210\/mend.15.6.0650","article-title":"Inhibin and p27 interact to regulate gonadal tumorigenesis.","volume":"15","author":"Cipriano","year":"2001","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R558","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1210\/me.2003-0039","article-title":"Sexually dimorphic roles of steroid hormone receptor signaling in gonadal tumorigenesis.","volume":"17","author":"Burns","year":"2003","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R559","first-page":"2788","article-title":"Induction of ovarian granulosa cell tumors in SWXJ-9 mice with dehydroepiandrosterone.","volume":"48","author":"Beamer","year":"1988","journal-title":"Cancer Res"},{"key":"2020071611592878700_R560","first-page":"1200","article-title":"Estrogen receptor isoform gene expression in ovarian stromal and epithelial tumors.","volume":"85","author":"Chu","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R561","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1210\/me.2002-0398","article-title":"Characterization of the hypothalamic-pituitary-gonadal axis in estrogen receptor (ER) null mice reveals hypergonadism and endocrine sex reversal in females lacking ER\u03b1 but not ER\u03b2.","volume":"17","author":"Couse","year":"2003","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R562","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1210\/me.2003-0038","article-title":"Cyclin D2 and p27 are tissue-specific regulators of tumorigenesis in inhibin \u03b1 knockout mice.","volume":"17","author":"Burns","year":"2003","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R563","doi-asserted-by":"crossref","first-page":"3837","DOI":"10.1210\/en.2006-1590","article-title":"Effects of granulosa cell-specific deletion of Rb in Inha-\u03b1 null female mice.","volume":"148","author":"Andreu-Vieyra","year":"2007","journal-title":"Endocrinology"},{"key":"2020071611592878700_R564","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrc2399","article-title":"Cellular mechanisms of tumour suppression by the retinoblastoma gene.","volume":"8","author":"Burkhart","year":"2008","journal-title":"Nat Rev Cancer"},{"key":"2020071611592878700_R565","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.molcel.2004.09.029","article-title":"An Rb-Skp2\u2013p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant.","volume":"16","author":"Ji","year":"2004","journal-title":"Mol Cell"},{"key":"2020071611592878700_R566","doi-asserted-by":"crossref","first-page":"373","DOI":"10.4161\/cc.4.3.1535","article-title":"Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression.","volume":"4","author":"Ji","year":"2005","journal-title":"Cell Cycle"},{"key":"2020071611592878700_R567","first-page":"534","article-title":"Activin signaling through activin receptor type II causes the cachexia-like symptoms in inhibin-deficient mice.","volume":"10","author":"Coerver","year":"1996","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R568","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/hep.1840180219","article-title":"Activin induces cell death in hepatocytes in vivo and in vitro.","volume":"18","author":"Schwall","year":"1993","journal-title":"Hepatology"},{"key":"2020071611592878700_R569","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/hep.1840200413","article-title":"Induction of apoptosis in the murine liver with recombinant human activin A.","volume":"20","author":"Hully","year":"1994","journal-title":"Hepatology"},{"key":"2020071611592878700_R570","first-page":"983","article-title":"Characterization of gonadal sex cord-stromal tumor cell lines from inhibin-\u03b1 and p53-deficient mice: the role of activin as an autocrine growth factor.","volume":"8","author":"Shikone","year":"1994","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R571","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1210\/endo.141.7.7535","article-title":"Follistatin is a modulator of gonadal tumor progression and the activin-induced wasting syndrome in inhibin-deficient mice.","volume":"141","author":"Cipriano","year":"2000","journal-title":"Endocrinology"},{"key":"2020071611592878700_R572","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1093\/molehr\/gam055","article-title":"Prevention of cachexia-like syndrome development and reduction of tumor progression in inhibin-deficient mice following administration of a chimeric activin receptor type II-murine Fc protein.","volume":"13","author":"Li","year":"2007","journal-title":"Mol Hum Reprod"},{"key":"2020071611592878700_R573","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1210\/me.2007-0147","article-title":"SMAD3 regulates gonadal tumorigenesis.","volume":"21","author":"Li","year":"2007","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R574","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1210\/me.2006-0402","article-title":"Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery.","volume":"21","author":"Looyenga","year":"2007","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R575","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1210\/me.2003-0414","article-title":"Ovarian follicle development requires Smad3.","volume":"18","author":"Tomic","year":"2004","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R576","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1128\/MCB.01404-07","article-title":"Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.","volume":"28","author":"Pangas","year":"2008","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R577","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1006\/gyno.1997.4635","article-title":"Hormone synthesis and responsiveness of spontaneous granulosa cell tumors in (SWR \u00d7 SWXJ-9) F1 mice.","volume":"65","author":"Gocze","year":"1997","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R578","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1056\/NEJM198909213211204","article-title":"Inhibin as a marker for granulosa-cell tumors.","volume":"321","author":"Lapp\u00f6hn","year":"1989","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R579","first-page":"187","article-title":"Is potential to produce inhibins related to prognosis in ovarian granulosa cell tumors?","volume":"21","author":"Ala-Fossi","year":"2000","journal-title":"Eur J Gynaecol Oncol"},{"key":"2020071611592878700_R580","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1210\/endo.143.3.8684","article-title":"Regulated expression of Wnts and Frizzleds at specific stages of follicular development in the rodent ovary.","volume":"143","author":"Hsieh","year":"2002","journal-title":"Endocrinology"},{"key":"2020071611592878700_R581","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1210\/endo.143.7.8908","article-title":"Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs.","volume":"143","author":"Ricken","year":"2002","journal-title":"Endocrinology"},{"key":"2020071611592878700_R582","doi-asserted-by":"crossref","first-page":"4597","DOI":"10.1210\/en.2003-0048","article-title":"Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells.","volume":"144","author":"Hsieh","year":"2003","journal-title":"Endocrinology"},{"key":"2020071611592878700_R583","doi-asserted-by":"crossref","first-page":"9206","DOI":"10.1158\/0008-5472.CAN-05-1024","article-title":"Misregulated Wnt\/\u03b2-catenin signaling leads to ovarian granulosa cell tumor development.","volume":"65","author":"Boerboom","year":"2005","journal-title":"Cancer Res"},{"key":"2020071611592878700_R584","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1158\/0008-5472.CAN-05-3493","article-title":"Dominant-stable \u03b2-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model.","volume":"66","author":"Boerboom","year":"2006","journal-title":"Cancer Res"},{"key":"2020071611592878700_R585","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1093\/carcin\/bgn186","article-title":"Synergistic effects of Pten loss and WNT\/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.","volume":"29","author":"Lagu\u00eb","year":"2008","journal-title":"Carcinogenesis"},{"key":"2020071611592878700_R586","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.cellsig.2006.02.011","article-title":"FSH signaling pathways in immature granulosa cells that regulate target gene expression: branching out from protein kinase A.","volume":"18","author":"Hunzicker-Dunn","year":"2006","journal-title":"Cell Signal"},{"key":"2020071611592878700_R587","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1056\/NEJMoa0902542","article-title":"Mutation of FOXL2 in granulosa-cell tumors of the ovary.","volume":"360","author":"Shah","year":"2009","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R588","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.ctrv.2008.02.002","article-title":"Germ cell tumors of the ovary.","volume":"34","author":"Pectasides","year":"2008","journal-title":"Cancer Treat Rev"},{"key":"2020071611592878700_R589","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1097\/01.AOG.0000216004.22588.ce","article-title":"Incidence and survival rates for female malignant germ cell tumors.","volume":"107","author":"Smith","year":"2006","journal-title":"Obstet Gynecol"},{"key":"2020071611592878700_R590","first-page":"635","article-title":"Genetics and biology of human ovarian teratomas. I. Cytogenetic analysis and mechanism of origin.","volume":"47","author":"Surti","year":"1990","journal-title":"Am J Hum Genet"},{"key":"2020071611592878700_R591","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0165-4608(92)90040-F","article-title":"Genetics and biology of human ovarian teratomas. III. Cytogenetics and origins of malignant ovarian germ cell tumors.","volume":"62","author":"Hoffner","year":"1992","journal-title":"Cancer Genet Cytogenet"},{"key":"2020071611592878700_R592","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0012-1606(74)90155-9","article-title":"The development of teratomas from parthenogenetically activated ovarian mouse eggs.","volume":"37","author":"Stevens","year":"1974","journal-title":"Dev Biol"},{"key":"2020071611592878700_R593","first-page":"5047","article-title":"Genetic regulation of traits essential for spontaneous ovarian teratocarcinogenesis in strain LT\/Sv mice: aberrant meiotic cell cycle, oocyte activation, and parthenogenetic development.","volume":"56","author":"Eppig","year":"1996","journal-title":"Cancer Res"},{"key":"2020071611592878700_R594","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/(SICI)1098-2795(199711)48:3<391::AID-MRD13>3.0.CO;2-Z","article-title":"Parthenogenetic development of Mos-deficient mouse oocytes.","volume":"48","author":"Hirao","year":"1997","journal-title":"Mol Reprod Dev"},{"key":"2020071611592878700_R595","first-page":"590","article-title":"Genetic dissection of susceptibility to murine ovarian teratomas that originate from parthenogenetic oocytes.","volume":"57","author":"Lee","year":"1997","journal-title":"Cancer Res"},{"key":"2020071611592878700_R596","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/269517a0","article-title":"Ovarian teratomas in mice are derived from oocytes that have completed the first meiotic division.","volume":"269","author":"Eppig","year":"1977","journal-title":"Nature"},{"key":"2020071611592878700_R597","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/0012-1606(78)90195-1","article-title":"Developmental potential of LT\/Sv parthenotes derived from oocytes matured in vivo and in vitro.","volume":"65","author":"Eppig","year":"1978","journal-title":"Dev Biol"},{"key":"2020071611592878700_R598","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1095\/biolreprod.108.069609","article-title":"Metaphase I arrest in LT\/Sv mouse oocytes involves the spindle assembly checkpoint.","volume":"79","author":"Hupalowska","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R599","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1242\/dev.121.4.925","article-title":"Analysis of the mechanism(s) of metaphase I arrest in maturing mouse oocytes.","volume":"121","author":"Hampl","year":"1995","journal-title":"Development"},{"key":"2020071611592878700_R600","doi-asserted-by":"crossref","first-page":"5107","DOI":"10.1242\/dev.124.24.5107","article-title":"Analysis of the mechanism(s) of metaphase I arrest in strain LT mouse oocytes: participation of MOS.","volume":"124","author":"Hirao","year":"1997","journal-title":"Development"},{"key":"2020071611592878700_R601","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1006\/dbio.1998.8930","article-title":"Cytostatic activity develops during meiosis I in oocytes of LT\/Sv mice.","volume":"200","author":"Ciemerych","year":"1998","journal-title":"Dev Biol"},{"key":"2020071611592878700_R602","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1098-2795(199911)54:3<311::AID-MRD12>3.0.CO;2-X","article-title":"Analysis of the mechanism(s) of metaphase I-arrest in strain LT mouse oocytes: delay in the acquisition of competence to undergo the metaphase I\/anaphase transition.","volume":"54","author":"Hirao","year":"1999","journal-title":"Mol Reprod Dev"},{"key":"2020071611592878700_R603","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/370020a0","article-title":"Embryology. On the loss of Mos.","volume":"370","author":"Vande Woude","year":"1994","journal-title":"Nature"},{"key":"2020071611592878700_R604","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1349-7006.1995.tb02432.x","article-title":"Ovarian teratomas in mice lacking the protooncogene c-mos.","volume":"86","author":"Furuta","year":"1995","journal-title":"Jpn J Cancer Res"},{"key":"2020071611592878700_R605","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1006\/dbio.2000.9764","article-title":"Metaphase I arrest and spontaneous parthenogenetic activation of strain LTXBO oocytes: chimeric reaggregated ovaries establish primary lesion in oocytes.","volume":"224","author":"Eppig","year":"2000","journal-title":"Dev Biol"},{"key":"2020071611592878700_R606","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1432-0436.1979.tb00996.x","article-title":"Granulosa cell deficient follicles: occurrence, structure, and relationship to ovarian teratocarcinogenesis in strain LT\/Sv mice.","volume":"12","author":"Eppig","year":"1978","journal-title":"Differentiation"},{"key":"2020071611592878700_R607","doi-asserted-by":"crossref","first-page":"4837","DOI":"10.1210\/endo.137.11.8895354","article-title":"Targeted overexpression of Bcl-2 in ovaries of transgenic mice leads to decreased follicle apoptosis, enhanced folliculogenesis, and increased germ cell tumorigenesis.","volume":"137","author":"Hsu","year":"1996","journal-title":"Endocrinology"},{"key":"2020071611592878700_R608","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1210\/mend.13.6.0306","article-title":"Targeted expression of Bcl-2 in mouse oocytes inhibits ovarian follicle atresia and prevents spontaneous and chemotherapy-induced oocyte apoptosis in vitro.","volume":"13","author":"Morita","year":"1999","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R609","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molcel.2007.12.010","article-title":"Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs.","volume":"29","author":"Wu","year":"2008","journal-title":"Mol Cell"},{"key":"2020071611592878700_R610","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1126\/science.1149460","article-title":"Switching from repression to activation: microRNAs can up-regulate translation.","volume":"318","author":"Vasudevan","year":"2007","journal-title":"Science"},{"key":"2020071611592878700_R611","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1101\/gr.082701.108","article-title":"Most mammalian mRNAs are conserved targets of microRNAs.","volume":"19","author":"Friedman","year":"2009","journal-title":"Genome Res"},{"key":"2020071611592878700_R612","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nature04916","article-title":"A novel class of small RNAs bind to MILI protein in mouse testes.","volume":"442","author":"Aravin","year":"2006","journal-title":"Nature"},{"key":"2020071611592878700_R613","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nature04917","article-title":"A germline-specific class of small RNAs binds mammalian Piwi proteins.","volume":"442","author":"Girard","year":"2006","journal-title":"Nature"},{"key":"2020071611592878700_R614","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1101\/gad.1434406","article-title":"A novel class of small RNAs in mouse spermatogenic cells.","volume":"20","author":"Grivna","year":"2006","journal-title":"Genes Dev"},{"key":"2020071611592878700_R615","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1126\/science.1130164","article-title":"Characterization of the piRNA complex from rat testes.","volume":"313","author":"Lau","year":"2006","journal-title":"Science"},{"key":"2020071611592878700_R616","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1101\/gad.1425706","article-title":"Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes.","volume":"20","author":"Watanabe","year":"2006","journal-title":"Genes Dev"},{"key":"2020071611592878700_R617","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1126\/science.1137543","article-title":"piRNAs in the germ line.","volume":"316","author":"Lin","year":"2007","journal-title":"Science"},{"key":"2020071611592878700_R618","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cell.2007.03.028","article-title":"Mighty Piwis defend the germline against genome intruders.","volume":"129","author":"O'Donnell","year":"2007","journal-title":"Cell"},{"key":"2020071611592878700_R619","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/nrm2347","article-title":"Small non-coding RNAs in animal development.","volume":"9","author":"Stefani","year":"2008","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2020071611592878700_R620","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/nrm2321","article-title":"Argonaute proteins: key players in RNA silencing.","volume":"9","author":"Hutvagner","year":"2008","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2020071611592878700_R621","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S1534-5807(02)00165-X","article-title":"miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis.","volume":"2","author":"Deng","year":"2002","journal-title":"Dev Cell"},{"key":"2020071611592878700_R622","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1242\/dev.00973","article-title":"Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.","volume":"131","author":"Kuramochi-Miyagawa","year":"2004","journal-title":"Development"},{"key":"2020071611592878700_R623","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.devcel.2007.03.001","article-title":"MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline.","volume":"12","author":"Carmell","year":"2007","journal-title":"Dev Cell"},{"key":"2020071611592878700_R624","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1126\/science.1142612","article-title":"Developmentally regulated piRNA clusters implicate MILI in transposon control.","volume":"316","author":"Aravin","year":"2007","journal-title":"Science"},{"key":"2020071611592878700_R625","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1261\/rna.754207","article-title":"Cloning and expression profiling of small RNAs expressed in the mouse ovary.","volume":"13","author":"Ro","year":"2007","journal-title":"RNA"},{"key":"2020071611592878700_R626","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/nature06908","article-title":"Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes.","volume":"453","author":"Watanabe","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R627","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/nature06904","article-title":"Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes.","volume":"453","author":"Tam","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R628","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1101\/gad.1521307","article-title":"Critical roles for Dicer in the female germline.","volume":"21","author":"Murchison","year":"2007","journal-title":"Genes Dev"},{"key":"2020071611592878700_R629","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1101\/gad.418707","article-title":"Maternal microRNAs are essential for mouse zygotic development.","volume":"21","author":"Tang","year":"2007","journal-title":"Genes Dev"},{"key":"2020071611592878700_R630","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1530\/rep.1.00364","article-title":"Cytoskeleton and cell cycle control during meiotic maturation of the mouse oocyte: integrating time and space.","volume":"130","author":"Brunet","year":"2005","journal-title":"Reproduction"},{"key":"2020071611592878700_R631","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1210\/me.2008-0142","article-title":"Deletion of Dicer in somatic cells of the female reproductive tract causes sterility.","volume":"22","author":"Nagaraja","year":"2008","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R632","doi-asserted-by":"crossref","first-page":"6207","DOI":"10.1210\/en.2008-0294","article-title":"Dicer1 is essential for female fertility and normal development of the female reproductive system.","volume":"149","author":"Hong","year":"2008","journal-title":"Endocrinology"},{"key":"2020071611592878700_R633","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1002\/mrd.21010","article-title":"Dicer is required for female reproductive tract development and fertility in the mouse.","volume":"76","author":"Gonzalez","year":"2009","journal-title":"Mol Reprod Dev"},{"key":"2020071611592878700_R634","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s00335-008-9169-y","article-title":"Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.","volume":"20","author":"Pastorelli","year":"2009","journal-title":"Mamm Genome"},{"key":"2020071611592878700_R635","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1095\/biolreprod.108.069690","article-title":"Hormonal regulation of microRNA expression in periovulatory mouse mural granulosa cells.","volume":"79","author":"Fiedler","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R636","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1172\/JCI33680","article-title":"Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice.","volume":"118","author":"Otsuka","year":"2008","journal-title":"J Clin Invest"},{"key":"2020071611592878700_R637","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature03702","article-title":"MicroRNA expression profiles classify human cancers.","volume":"435","author":"Lu","year":"2005","journal-title":"Nature"},{"key":"2020071611592878700_R638","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/ng2003","article-title":"Impaired microRNA processing enhances cellular transformation and tumorigenesis.","volume":"39","author":"Kumar","year":"2007","journal-title":"Nat Genet"},{"key":"2020071611592878700_R639","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1073\/pnas.0307323101","article-title":"Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.","volume":"101","author":"Calin","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R640","doi-asserted-by":"crossref","first-page":"9136","DOI":"10.1073\/pnas.0508889103","article-title":"microRNAs exhibit high frequency genomic alterations in human cancer.","volume":"103","author":"Zhang","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R641","doi-asserted-by":"crossref","first-page":"7004","DOI":"10.1073\/pnas.0801615105","article-title":"Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.","volume":"105","author":"Zhang","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R642","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1002\/ijc.23325","article-title":"MicroRNA epigenetic alterations in human cancer: one step forward in diagnosis and treatment.","volume":"122","author":"Yang","year":"2008","journal-title":"Int J Cancer"},{"key":"2020071611592878700_R643","doi-asserted-by":"crossref","first-page":"8535","DOI":"10.1158\/0008-5472.CAN-08-2129","article-title":"A SNP in a let-7 microRNA complementary site in the KRAS 3\u2032 untranslated region increases non-small cell lung cancer risk.","volume":"68","author":"Chin","year":"2008","journal-title":"Cancer Res"},{"key":"2020071611592878700_R644","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.4161\/cc.7.17.6597","article-title":"Mechanisms of microRNA deregulation in human cancer.","volume":"7","author":"Deng","year":"2008","journal-title":"Cell Cycle"},{"key":"2020071611592878700_R645","doi-asserted-by":"crossref","first-page":"8699","DOI":"10.1158\/0008-5472.CAN-07-1936","article-title":"MicroRNA signatures in human ovarian cancer.","volume":"67","author":"Iorio","year":"2007","journal-title":"Cancer Res"},{"key":"2020071611592878700_R646","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1158\/1078-0432.CCR-07-1731","article-title":"MicroRNA expression profiles in serous ovarian carcinoma.","volume":"14","author":"Nam","year":"2008","journal-title":"Clin Cancer Res"},{"key":"2020071611592878700_R647","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1158\/0008-5472.CAN-07-2488","article-title":"MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN.","volume":"68","author":"Yang","year":"2008","journal-title":"Cancer Res"},{"key":"2020071611592878700_R648","first-page":"4575","article-title":"Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells.","volume":"62","author":"Alfonso-De Matte","year":"2002","journal-title":"Cancer Res"},{"key":"2020071611592878700_R649","doi-asserted-by":"crossref","first-page":"e2436","DOI":"10.1371\/journal.pone.0002436","article-title":"MicroRNA expression and identification of putative miRNA targets in ovarian cancer","volume":"3","author":"Dahiya","year":"2008","journal-title":"PLoS ONE"},{"key":"2020071611592878700_R650","first-page":"4811","article-title":"Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies.","volume":"9","author":"Zorn","year":"2003","journal-title":"Clin Cancer Res"},{"key":"2020071611592878700_R651","doi-asserted-by":"crossref","first-page":"8433","DOI":"10.1158\/0008-5472.CAN-07-1585","article-title":"MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth.","volume":"67","author":"Corney","year":"2007","journal-title":"Cancer Res"},{"key":"2020071611592878700_R652","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.cub.2007.06.068","article-title":"p53-mediated activation of miRNA34 candidate tumor-suppressor genes.","volume":"17","author":"Bommer","year":"2007","journal-title":"Curr Biol"},{"key":"2020071611592878700_R653","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.molcel.2007.05.010","article-title":"Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.","volume":"26","author":"Chang","year":"2007","journal-title":"Mol Cell"},{"key":"2020071611592878700_R654","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1038\/nature05939","article-title":"A microRNA component of the p53 tumour suppressor network.","volume":"447","author":"He","year":"2007","journal-title":"Nature"},{"key":"2020071611592878700_R655","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.molcel.2007.05.017","article-title":"Transcriptional activation of miR-34a contributes to p53-mediated apoptosis.","volume":"26","author":"Raver-Shapira","year":"2007","journal-title":"Mol Cell"},{"key":"2020071611592878700_R656","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.4161\/cc.6.13.4436","article-title":"Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.","volume":"6","author":"Tarasov","year":"2007","journal-title":"Cell Cycle"},{"key":"2020071611592878700_R657","doi-asserted-by":"crossref","first-page":"11099","DOI":"10.1158\/0008-5472.CAN-07-2672","article-title":"The guardian\u2019s little helper: microRNAs in the p53 tumor suppressor network.","volume":"67","author":"He","year":"2007","journal-title":"Cancer Res"},{"key":"2020071611592878700_R658","doi-asserted-by":"crossref","first-page":"5017","DOI":"10.1038\/sj.onc.1210293","article-title":"MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells.","volume":"26","author":"Welch","year":"2007","journal-title":"Oncogene"},{"key":"2020071611592878700_R659","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1101\/gad.1640608","article-title":"The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.","volume":"22","author":"Park","year":"2008","journal-title":"Genes Dev"},{"key":"2020071611592878700_R660","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.tcb.2008.05.005","article-title":"Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition.","volume":"18","author":"Cano","year":"2008","journal-title":"Trends Cell Biol"},{"key":"2020071611592878700_R661","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1002\/cncr.20946","article-title":"Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.","volume":"103","author":"Elloul","year":"2005","journal-title":"Cancer"},{"key":"2020071611592878700_R662","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/ncb1722","article-title":"The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.","volume":"10","author":"Gregory","year":"2008","journal-title":"Nat Cell Biol"},{"key":"2020071611592878700_R663","doi-asserted-by":"crossref","first-page":"14910","DOI":"10.1074\/jbc.C800074200","article-title":"The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.","volume":"283","author":"Korpal","year":"2008","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R664","first-page":"2095","article-title":"Frequent PTEN\/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors.","volume":"58","author":"Obata","year":"1998","journal-title":"Cancer Res"},{"key":"2020071611592878700_R665","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1016\/S0002-9440(10)64681-0","article-title":"Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.","volume":"158","author":"Kurose","year":"2001","journal-title":"Am J Pathol"},{"key":"2020071611592878700_R666","doi-asserted-by":"crossref","first-page":"10307","DOI":"10.1158\/0008-5472.CAN-08-1954","article-title":"MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer.","volume":"68","author":"Yang","year":"2008","journal-title":"Cancer Res"},{"key":"2020071611592878700_R667","doi-asserted-by":"crossref","first-page":"4712","DOI":"10.1038\/onc.2008.112","article-title":"Regulation of IKK\u03b2 by miR-199a affects NF-\u03baB activity in ovarian cancer cells.","volume":"27","author":"Chen","year":"2008","journal-title":"Oncogene"},{"key":"2020071611592878700_R668","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.ygyno.2008.08.017","article-title":"Role of microRNAs in drug-resistant ovarian cancer cells.","volume":"111","author":"Sorrentino","year":"2008","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R669","first-page":"999","article-title":"Overexpression of epithelial macrophage colony-stimulating factor (CSF-1) and CSF-1 receptor: a poor prognostic factor in epithelial ovarian cancer, contrasted with a protective effect of stromal CSF-1.","volume":"3","author":"Chambers","year":"1997","journal-title":"Clin Cancer Res"},{"key":"2020071611592878700_R670","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1006\/gyno.2000.6070","article-title":"The activated macrophage colony-stimulating factor (CSF-1) receptor as a predictor of poor outcome in advanced epithelial ovarian carcinoma.","volume":"80","author":"Toy","year":"2001","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R671","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/(SICI)1098-2795(199701)46:1<71::AID-MRD11>3.0.CO;2-6","article-title":"CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract.","volume":"46","author":"Kacinski","year":"1997","journal-title":"Mol Reprod Dev"},{"key":"2020071611592878700_R672","doi-asserted-by":"crossref","first-page":"4349","DOI":"10.1158\/0008-5472.CAN-05-3523","article-title":"Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts.","volume":"66","author":"Paulus","year":"2006","journal-title":"Cancer Res"},{"key":"2020071611592878700_R673","first-page":"1578","article-title":"Macrophage colony-stimulating factor mediates invasion of ovarian cancer cells through urokinase.","volume":"55","author":"Chambers","year":"1995","journal-title":"Cancer Res"},{"key":"2020071611592878700_R674","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1593\/neo.81150","article-title":"Enhanced ovarian cancer tumorigenesis and metastasis by the macrophage colony-stimulating factor.","volume":"11","author":"Toy","year":"2009","journal-title":"Neoplasia"},{"key":"2020071611592878700_R675","doi-asserted-by":"crossref","first-page":"3762","DOI":"10.1158\/0008-5472.CAN-04-3954","article-title":"Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-rich 3\u2032 untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype.","volume":"65","author":"Bonafe\u0301","year":"2005","journal-title":"Cancer Res"},{"key":"2020071611592878700_R676","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1158\/1541-7786.MCR-07-2170","article-title":"The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.","volume":"6","author":"Zhou","year":"2008","journal-title":"Mol Cancer Res"},{"key":"2020071611592878700_R677","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.cell.2005.01.014","article-title":"RAS is regulated by the let-7 microRNA family.","volume":"120","author":"Johnson","year":"2005","journal-title":"Cell"},{"key":"2020071611592878700_R678","doi-asserted-by":"crossref","first-page":"9762","DOI":"10.1158\/0008-5472.CAN-07-2462","article-title":"MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.","volume":"67","author":"Sampson","year":"2007","journal-title":"Cancer Res"},{"key":"2020071611592878700_R679","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1126\/science.1137999","article-title":"Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation.","volume":"315","author":"Mayr","year":"2007","journal-title":"Science"},{"key":"2020071611592878700_R680","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1101\/gad.1540407","article-title":"The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.","volume":"21","author":"Lee","year":"2007","journal-title":"Genes Dev"},{"key":"2020071611592878700_R681","doi-asserted-by":"crossref","first-page":"11400","DOI":"10.1073\/pnas.0704372104","article-title":"Let-7 expression defines two differentiation stages of cancer.","volume":"104","author":"Shell","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R682","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.4161\/cc.6.21.4845","article-title":"Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.","volume":"6","author":"Park","year":"2007","journal-title":"Cell Cycle"},{"key":"2020071611592878700_R683","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/ijc.23491","article-title":"HMGA2 gene is a promising target for ovarian cancer silencing therapy.","volume":"123","author":"Malek","year":"2008","journal-title":"Int J Cancer"},{"key":"2020071611592878700_R684","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.cell.2007.10.054","article-title":"Let-7 regulates self renewal and tumorigenicity of breast cancer cells.","volume":"131","author":"Yu","year":"2007","journal-title":"Cell"},{"key":"2020071611592878700_R685","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1016\/j.ejca.2009.05.003","article-title":"Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.","volume":"45","author":"Lu","year":"2009","journal-title":"Eur J Cancer"},{"key":"2020071611592878700_R686","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1056\/NEJMoa0803785","article-title":"Dicer, Drosha, and outcomes in patients with ovarian cancer.","volume":"359","author":"Merritt","year":"2008","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R687","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/modpathol.2008.33","article-title":"Altered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients.","volume":"21","author":"Flavin","year":"2008","journal-title":"Mod Pathol"},{"key":"2020071611592878700_R688","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/nature05841","article-title":"MicroRNA silencing through RISC recruitment of eIF6.","volume":"447","author":"Chendrimada","year":"2007","journal-title":"Nature"},{"key":"2020071611592878700_R689","doi-asserted-by":"crossref","first-page":"10513","DOI":"10.1073\/pnas.0804549105","article-title":"Circulating microRNAs as stable blood-based markers for cancer detection.","volume":"105","author":"Mitchell","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R690","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/cr.2008.282","article-title":"Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases.","volume":"18","author":"Chen","year":"2008","journal-title":"Cell Res"},{"key":"2020071611592878700_R691","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/ncb1596","article-title":"Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.","volume":"9","author":"Valadi","year":"2007","journal-title":"Nat Cell Biol"},{"key":"2020071611592878700_R692","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ygyno.2008.04.033","article-title":"MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.","volume":"110","author":"Taylor","year":"2008","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R693","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ygyno.2008.08.036","article-title":"The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform.","volume":"112","author":"Resnick","year":"2009","journal-title":"Gynecol Oncol"},{"key":"2020071611592878700_R694","first-page":"S41","article-title":"Genetic dissection of mammalian fertility pathways","volume":"Suppl","author":"Matzuk","year":"2002","journal-title":"Nat Cell Biol 4"},{"key":"2020071611592878700_R695","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1038\/nm.f.1895","article-title":"The biology of infertility: research advances and clinical challenges.","volume":"14","author":"Matzuk","year":"2008","journal-title":"Nat Med"},{"key":"2020071611592878700_R696","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/humrep\/dem046","article-title":"International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care.","volume":"22","author":"Boivin","year":"2007","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R697","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1093\/humupd\/dmh044","article-title":"Historical perspectives in gonadotrophin therapy.","volume":"10","author":"Lunenfeld","year":"2004","journal-title":"Hum Reprod Update"},{"key":"2020071611592878700_R698","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1210\/er.2005-0015","article-title":"The science behind 25 years of ovarian stimulation for in vitro fertilization.","volume":"27","author":"Macklon","year":"2006","journal-title":"Endocr Rev"},{"key":"2020071611592878700_R699","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0140-6736(78)92957-4","article-title":"Birth after the reimplantation of a human embryo.","volume":"2","author":"Steptoe","year":"1978","journal-title":"Lancet"},{"key":"2020071611592878700_R700","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1126\/science.7221557","article-title":"Pregnancies in humans by fertilization in vitro and embryo transfer in the controlled ovulatory cycle.","volume":"212","author":"Trounson","year":"1981","journal-title":"Science"},{"key":"2020071611592878700_R701","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1073\/pnas.89.10.4304","article-title":"Design of a long-acting follitropin agonist by fusing the C-terminal sequence of the chorionic gonadotropin \u03b2 subunit to the follitropin \u03b2 subunit.","volume":"89","author":"Fares","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R702","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.fertnstert.2004.12.027","article-title":"Effects of long-acting recombinant human follicle-stimulating hormone analogs containing N-linked glycosylation on murine folliculogenesis.","volume":"83(Suppl 1)","author":"Ruman","year":"2005","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R703","doi-asserted-by":"crossref","first-page":"10445","DOI":"10.1074\/jbc.271.18.10445","article-title":"Expression of biologically active fusion genes encoding the common \u03b1 subunit and the follicle-stimulating hormone \u03b2 subunit. Role of a linker sequence.","volume":"271","author":"Sugahara","year":"1996","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R704","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1210\/jc.2003-031766","article-title":"Induction of multiple follicular development by a single dose of long-acting recombinant follicle-stimulating hormone (FSH-CTP, corifollitropin alfa) for controlled ovarian stimulation before in vitro fertilization.","volume":"89","author":"Devroey","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071611592878700_R705","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1093\/humrep\/den288","article-title":"A randomized dose-response trial of a single injection of corifollitropin alfa to sustain multifollicular growth during controlled ovarian stimulation.","volume":"23","year":"2008","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R706","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/humupd\/dmn065","article-title":"Advances in recombinant DNA technology: corifollitropin alfa, a hybrid molecule with sustained follicle-stimulating activity and reduced injection frequency.","volume":"15","author":"Fauser","year":"2009","journal-title":"Hum Reprod Update"},{"key":"2020071611592878700_R707","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12020-008-9098-2","article-title":"Allosteric modulators of glycoprotein hormone receptors: discovery and therapeutic potential.","volume":"34","author":"Arey","year":"2008","journal-title":"Endocrine"},{"key":"2020071611592878700_R708","doi-asserted-by":"crossref","first-page":"13226","DOI":"10.1074\/jbc.M600601200","article-title":"Allosteric activation of the follicle-stimulating hormone (FSH) receptor by selective, nonpeptide agonists.","volume":"281","author":"Yanofsky","year":"2006","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R709","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1016\/j.bmcl.2006.12.062","article-title":"Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists.","volume":"17","author":"Jorand-Lebrun","year":"2007","journal-title":"Bioorg Med Chem Lett"},{"key":"2020071611592878700_R710","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/humrep\/den412","article-title":"Induction of ovulation by a potent, orally active, low molecular weight agonist (Org 43553) of the luteinizing hormone receptor.","volume":"24","author":"Lagemaat","year":"2009","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R711","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1124\/mol.107.039875","article-title":"[3H]Org 43553, the first low-molecular-weight agonistic and allosteric radioligand for the human luteinizing hormone receptor.","volume":"73","author":"Heitman","year":"2008","journal-title":"Mol Pharmacol"},{"key":"2020071611592878700_R712","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.ucl.2008.01.004","article-title":"Intracytoplasmic sperm injection (ICSI)\u2014what are the risks?","volume":"35","author":"Alukal","year":"2008","journal-title":"Urol Clin North Am"},{"key":"2020071611592878700_R713","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.fertnstert.2009.01.002","article-title":"Imprinting disorders and assisted reproductive technology.","volume":"91","author":"Manipalviratn","year":"2009","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R714","doi-asserted-by":"crossref","first-page":"S182","DOI":"10.1016\/j.fertnstert.2008.08.048","article-title":"Genetic considerations related to intracytoplasmic sperm injection (ICSI)","volume":"90","year":"2008","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R715","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/humrep\/den387","article-title":"Assisted reproductive technology and major structural birth defects in the United States.","volume":"24","author":"Reefhuis","year":"2009","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R716","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0041-008X(80)90424-X","article-title":"Morphology of oocyte and follicle destruction by polycyclic aromatic hydrocarbons in mice.","volume":"53","author":"Mattison","year":"1980","journal-title":"Toxicol Appl Pharmacol"},{"key":"2020071611592878700_R717","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/S0140-6736(86)90989-X","article-title":"Pregnancy after human oocyte cryopreservation.","volume":"1","author":"Chen","year":"1986","journal-title":"Lancet"},{"key":"2020071611592878700_R718","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.theriogenology.2006.09.012","article-title":"Analysis of oocyte physiology to improve cryopreservation procedures.","volume":"67","author":"Gardner","year":"2007","journal-title":"Theriogenology"},{"key":"2020071611592878700_R719","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S1472-6483(10)60837-1","article-title":"Highly efficient vitrification method for cryopreservation of human oocytes.","volume":"11","author":"Kuwayama","year":"2005","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R720","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S1472-6483(10)61091-7","article-title":"Are programmable freezers still needed in the embryo laboratory? Review on vitrification.","volume":"12","author":"Vajta","year":"2006","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R721","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.fertnstert.2005.09.013","article-title":"Successful ongoing pregnancies after vitrification of oocytes.","volume":"85","author":"Lucena","year":"2006","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R722","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S1472-6483(10)60766-3","article-title":"Cryotop vitrification of human oocytes results in high survival rate and healthy deliveries.","volume":"14","author":"Antinori","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R723","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.fertnstert.2006.04.052","article-title":"Report of four donor-recipient oocyte cryopreservation cycles resulting in high pregnancy and implantation rates.","volume":"87","author":"Barritt","year":"2007","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R724","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S1472-6483(10)60594-9","article-title":"Two successful pregnancies obtained following oocyte vitrification and embryo re-vitrification.","volume":"16","author":"Chang","year":"2008","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R725","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S1472-6483(10)60316-1","article-title":"Human oocyte vitrification: in-vivo and in-vitro maturation outcomes.","volume":"17","author":"Chang","year":"2008","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R726","author":"Cao","year":"20 2008"},{"key":"2020071611592878700_R727","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/S1472-6483(10)60537-8","article-title":"Maintenance of the meiotic spindle during vitrification in human and mouse oocytes.","volume":"15","author":"Larman","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R728","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1016\/j.fertnstert.2008.03.013","article-title":"Meiotic spindle recovery is faster in vitrification of human oocytes compared to slow freezing.","volume":"91","author":"Ciotti","year":"2009","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R729","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/humrep\/deh605","article-title":"Aseptic technology of vitrification of human pronuclear oocytes using open-pulled straws.","volume":"20","author":"Isachenko","year":"2005","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R730","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S1472-6483(10)60982-0","article-title":"Vitrification of mouse pronuclear oocytes with no direct liquid nitrogen contact.","volume":"12","author":"Larman","year":"2006","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R731","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1093\/humrep\/den222","article-title":"A randomized controlled study of human day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.","volume":"23","author":"Balaban","year":"2008","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R732","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S1472-6483(10)60670-0","article-title":"Production of the first offspring from oocytes derived from fresh and cryopreserved pre-antral follicles of adult mice.","volume":"14","author":"Kagawa","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R733","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1159\/000086891","article-title":"Effect of maternal age on the frequency of cytogenetic abnormalities in human oocytes.","volume":"111","author":"Pellestor","year":"2005","journal-title":"Cytogenet Genome Res"},{"key":"2020071611592878700_R734","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1472-6483(10)61724-5","article-title":"Imaging meiotic spindles by polarization light microscopy: principles and applications to IVF.","volume":"7","author":"Keefe","year":"2003","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R735","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0015-0282(00)01692-7","article-title":"The spindle observation and its relationship with fertilization after intracytoplasmic sperm injection in living human oocytes.","volume":"75","author":"Wang","year":"2001","journal-title":"Fertil Steril"},{"key":"2020071611592878700_R736","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1093\/humrep\/16.7.1464","article-title":"Developmental ability of human oocytes with or without birefringent spindles imaged by polscope before insemination.","volume":"16","author":"Wang","year":"2001","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R737","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S1472-6483(10)60784-5","article-title":"Meiotic spindle and zona pellucida characteristics as predictors of embryonic development: a preliminary study using PolScope imaging.","volume":"14","author":"Rama Raju","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R738","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S1472-6483(10)60261-1","article-title":"Relationship between visualization of meiotic spindle in human oocytes and ICSI outcomes: a meta-analysis.","volume":"18","author":"Petersen","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R739","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S1472-6483(10)60109-5","article-title":"Polar body biopsy: a viable alternative to preimplantation genetic diagnosis and screening.","volume":"18(Suppl 1)","author":"Montag","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"2020071611592878700_R740","author":"Keskintepe","year":"20 2008"},{"key":"2020071611592878700_R741","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1093\/humrep\/den048","article-title":"Identification of differentially expressed markers in human follicular cells associated with competent oocytes.","volume":"23","author":"Hamel","year":"2008","journal-title":"Hum Reprod"},{"key":"2020071611592878700_R742","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/molehr\/gan067","article-title":"A non-invasive test for assessing embryo potential by gene expression profiles of human cumulus cells: a proof of concept study.","volume":"14","author":"Assou","year":"2008","journal-title":"Mol Hum Reprod"},{"key":"2020071611592878700_R743","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1126\/science.1083452","article-title":"Derivation of oocytes from mouse embryonic stem cells.","volume":"300","author":"H\u00fcbner","year":"2003","journal-title":"Science"},{"key":"2020071611592878700_R744","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0092-8674(92)90317-6","article-title":"Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture.","volume":"70","author":"Matsui","year":"1992","journal-title":"Cell"},{"key":"2020071611592878700_R745","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/359550a0","article-title":"Long-term proliferation of mouse primordial germ cells in culture.","volume":"359","author":"Resnick","year":"1992","journal-title":"Nature"},{"key":"2020071611592878700_R746","doi-asserted-by":"crossref","first-page":"e3531","DOI":"10.1371\/journal.pone.0003531","article-title":"Reprogramming primordial germ cells into pluripotent stem cells","volume":"3","author":"Durcova-Hills","year":"2008","journal-title":"PLoS ONE"},{"key":"2020071611592878700_R747","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1634\/stemcells.2005-0424","article-title":"The role of exogenous fibroblast growth factor-2 on the reprogramming of primordial germ cells into pluripotent stem cells.","volume":"24","author":"Durcova-Hills","year":"2006","journal-title":"Stem Cells"},{"key":"2020071611592878700_R748","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/nature04697","article-title":"Pluripotency of spermatogonial stem cells from adult mouse testis.","volume":"440","author":"Guan","year":"2006","journal-title":"Nature"},{"key":"2020071611592878700_R749","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.cell.2004.11.011","article-title":"Generation of pluripotent stem cells from neonatal mouse testis.","volume":"119","author":"Kanatsu-Shinohara","year":"2004","journal-title":"Cell"},{"key":"2020071611592878700_R750","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/nature07404","article-title":"Generation of pluripotent stem cells from adult human testis.","volume":"456","author":"Conrad","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R751","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nature06534","article-title":"Reprogramming of human somatic cells to pluripotency with defined factors.","volume":"451","author":"Park","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R752","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1126\/science.1151526","article-title":"Induced pluripotent stem cell lines derived from human somatic cells.","volume":"318","author":"Yu","year":"2007","journal-title":"Science"},{"key":"2020071611592878700_R753","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/385810a0","article-title":"Viable offspring derived from fetal and adult mammalian cells.","volume":"385","author":"Wilmut","year":"1997","journal-title":"Nature"},{"key":"2020071611592878700_R754","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1071\/RD08218","article-title":"Nuclear transfer and oocyte cryopreservation.","volume":"21","author":"Chang","year":"2009","journal-title":"Reprod Fertil Dev"},{"key":"2020071611592878700_R755","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.tem.2006.03.010","article-title":"Mining the oocyte transcriptome.","volume":"17","author":"Andreu-Vieyra","year":"2006","journal-title":"Trends Endocrinol Metab"},{"key":"2020071611592878700_R756","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1210\/endo.141.9.7679","article-title":"The Ovarian Kaleidoscope database: an online resource for the ovarian research community.","volume":"141","author":"Leo","year":"2000","journal-title":"Endocrinology"},{"key":"2020071611592878700_R757","first-page":"604","article-title":"Incidence of premature ovarian failure.","volume":"67","author":"Coulam","year":"1986","journal-title":"Obstet Gynecol"},{"key":"2020071611592878700_R758","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/1096-8628(200023)97:3<189::AID-AJMG1036>3.0.CO;2-J","article-title":"Premature ovarian failure in the fragile X syndrome.","volume":"97","author":"Sherman","year":"2000","journal-title":"Am J Med Genet"},{"key":"2020071611592878700_R759","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/nature02168","article-title":"The International HapMap Project.","volume":"426","year":"2003","journal-title":"Nature"},{"key":"2020071611592878700_R760","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/jbiol84","article-title":"Appetite for reproduction: dietary restriction, aging and the mammalian gonad.","volume":"7","author":"Nalam","year":"2008","journal-title":"J Biol"},{"key":"2020071611592878700_R761","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1741-7007-6-24","article-title":"Effects of aging and calorie restriction on the global gene expression profiles of mouse testis and ovary.","volume":"6","author":"Sharov","year":"2008","journal-title":"BMC Biol"},{"key":"2020071611592878700_R762","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1095\/biolreprod.108.073619","article-title":"Female mice delay reproductive aging in males.","volume":"80","author":"Schmidt","year":"2009","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R763","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/nature04303","article-title":"Silencing of microRNAs in vivo with \u2018antagomirs.\u2019","volume":"438","author":"Kr\u00fctzfeldt","year":"2005","journal-title":"Nature"},{"key":"2020071611592878700_R764","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cmet.2006.01.005","article-title":"miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.","volume":"3","author":"Esau","year":"2006","journal-title":"Cell Metab"},{"key":"2020071611592878700_R765","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/nar\/gkm1113","article-title":"Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver.","volume":"36","author":"Elme\u0301n","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"2020071611592878700_R766","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/nature06783","article-title":"LNA-mediated microRNA silencing in non-human primates.","volume":"452","author":"Elme\u0301n","year":"2008","journal-title":"Nature"},{"key":"2020071611592878700_R767","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1126\/science.1113329","article-title":"Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA.","volume":"309","author":"Jopling","year":"2005","journal-title":"Science"},{"key":"2020071611592878700_R768","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1530\/jrf.0.0170555","article-title":"Proposal for a classification of oocytes and follicles in the mouse ovary.","volume":"17","author":"Pedersen","year":"1968","journal-title":"J Reprod Fertil"},{"key":"2020071611592878700_R769","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1056\/NEJMoa0900136","article-title":"Isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation.","volume":"360","author":"Bouligand","year":"2009","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R770","doi-asserted-by":"crossref","first-page":"11703","DOI":"10.1073\/pnas.0903449106","article-title":"GNRH1 mutations in patients with idiopathic hypogonadotropic hypogonadism.","volume":"106","author":"Chan","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R771","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1056\/NEJMoa0806228","article-title":"Mutations in NR5A1 associated with ovarian insufficiency.","volume":"360","author":"Lourenc\u0327o","year":"2009","journal-title":"N Engl J Med"},{"key":"2020071611592878700_R772","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1242\/dev.122.10.2977","article-title":"Mice deficient for BMP2 are nonviable and have defects in amnion\/chorion and cardiac development.","volume":"122","author":"Zhang","year":"1996","journal-title":"Development"},{"key":"2020071611592878700_R773","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1101\/gad.9.17.2105","article-title":"Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.","volume":"9","author":"Winnier","year":"1995","journal-title":"Genes Dev"},{"key":"2020071611592878700_R774","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1101\/gad.10.13.1657","article-title":"The gene encoding bone morphogeneetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.","volume":"10","author":"Zhao","year":"1996","journal-title":"Genes Dev"},{"key":"2020071611592878700_R775","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/dbio.2001.0469","article-title":"Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion.","volume":"240","author":"Lechleider","year":"2001","journal-title":"Dev Biol"},{"key":"2020071611592878700_R776","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1242\/dev.126.8.1631","article-title":"Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects.","volume":"126","author":"Chang","year":"1999","journal-title":"Development"},{"key":"2020071611592878700_R777","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1242\/dev.126.8.1571","article-title":"Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5.","volume":"126","author":"Yang","year":"1999","journal-title":"Development"},{"key":"2020071611592878700_R778","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1101\/gad.12.1.107","article-title":"The tumor suppressor gene Smad4\/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo.","volume":"12","author":"Sirard","year":"1998","journal-title":"Genes Dev"},{"key":"2020071611592878700_R779","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1073\/pnas.95.7.3667","article-title":"The tumor suppressor SMAD4\/DPC4 is essential for epiblast proliferation and mesoderm induction in mice.","volume":"95","author":"Yang","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R780","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1002\/j.1460-2075.1989.tb08392.x","article-title":"A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor.","volume":"8","author":"Sch\u00f6ler","year":"1989","journal-title":"EMBO J"},{"key":"2020071611592878700_R781","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.cell.2005.08.020","article-title":"Core transcriptional regulatory circuitry in human embryonic stem cells.","volume":"122","author":"Boyer","year":"2005","journal-title":"Cell"},{"key":"2020071611592878700_R782","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0092-8674(03)00392-1","article-title":"Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.","volume":"113","author":"Chambers","year":"2003","journal-title":"Cell"},{"key":"2020071611592878700_R783","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0092-8674(03)00393-3","article-title":"The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.","volume":"113","author":"Mitsui","year":"2003","journal-title":"Cell"},{"key":"2020071611592878700_R784","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1101\/gad.12.13.2073","article-title":"New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2.","volume":"12","author":"Botquin","year":"1998","journal-title":"Genes Dev"},{"key":"2020071611592878700_R785","author":"Donovan","year":"2001"},{"key":"2020071611592878700_R786","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1093\/emboj\/20.7.1663","article-title":"Abnormal angiogenesis but intact hematopoietic potential in TGF-\u03b2 type I receptor-deficient mice.","volume":"20","author":"Larsson","year":"2001","journal-title":"EMBO J"},{"key":"2020071611592878700_R787","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/90046","article-title":"Sox9 induces testis development in XX transgenic mice.","volume":"28","author":"Vidal","year":"2001","journal-title":"Nat Genet"},{"key":"2020071611592878700_R788","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/351117a0","article-title":"Male development of chromosomally female mice transgenic for Sry.","volume":"351","author":"Koopman","year":"1991","journal-title":"Nature"},{"key":"2020071611592878700_R789","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1101\/gad.1052503","article-title":"Pdgfr-\u03b1 mediates testis cord organization and fetal Leydig cell development in the XY gonad.","volume":"17","author":"Brennan","year":"2003","journal-title":"Genes Dev"},{"key":"2020071611592878700_R790","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ydbio.2006.02.027","article-title":"Sohlh1 is essential for spermatogonial differentiation.","volume":"294","author":"Ballow","year":"2006","journal-title":"Dev Biol"},{"key":"2020071611592878700_R791","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1210\/me.2007-0310","article-title":"A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Drd2, in the mouse.","volume":"22","author":"Kano","year":"2008","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R792","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1210\/endo.143.7.8921","article-title":"Deletion of exon 6 of the neuronal nitric oxide synthase gene in mice results in hypogonadism and infertility.","volume":"143","author":"Gyurko","year":"2002","journal-title":"Endocrinology"},{"key":"2020071611592878700_R793","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1128\/MCB.24.11.4720-4733.2004","article-title":"Disruption of CCT\u03b22 expression leads to gonadal dysfunction.","volume":"24","author":"Jackowski","year":"2004","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R794","doi-asserted-by":"crossref","first-page":"3066","DOI":"10.1128\/MCB.22.9.3066-3077.2002","article-title":"SH2-B is required for both male and female reproduction.","volume":"22","author":"Ohtsuka","year":"2002","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R795","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1385\/ENDO:26:2:169","article-title":"Alterations in reproductive function in SRC tyrosine kinase knockout mice.","volume":"26","author":"Roby","year":"2005","journal-title":"Endocrine"},{"key":"2020071611592878700_R796","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/jcp.20904","article-title":"Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).","volume":"210","author":"Greenaway","year":"2007","journal-title":"J Cell Physiol"},{"key":"2020071611592878700_R797","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1128\/MCB.22.2.525-535.2002","article-title":"Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction.","volume":"22","author":"Smith","year":"2002","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R798","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1095\/biolreprod.107.065987","article-title":"A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice.","volume":"78","author":"Lu","year":"2008","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R799","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/35030105","article-title":"IRS-2 pathways integrate femal reproduction and energy homeostasis.","volume":"407","author":"Burks","year":"2000","journal-title":"Nature"},{"key":"2020071611592878700_R800","doi-asserted-by":"crossref","first-page":"4008","DOI":"10.1210\/endo.139.9.6289","article-title":"Ovarian function in superoxide dismutase 1 and 2 knockout mice.","volume":"139","author":"Matzuk","year":"1998","journal-title":"Endocrinology"},{"key":"2020071611592878700_R801","doi-asserted-by":"crossref","first-page":"7765","DOI":"10.1074\/jbc.273.13.7765","article-title":"Reduced fertility in female mice lacking copper-zinc superoxide dismutase.","volume":"273","author":"Ho","year":"1998","journal-title":"J Biol Chem"},{"key":"2020071611592878700_R802","doi-asserted-by":"crossref","first-page":"8084","DOI":"10.1128\/MCB.23.22.8084-8091.2003","article-title":"Sox3 is required for gonadal function, but not sex determination, in males and females.","volume":"23","author":"Weiss","year":"2003","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R803","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1095\/biolreprod61.6.1616","article-title":"Alterations of events related to ovarian function in tumor necrosis factor receptor type I knockout mice.","volume":"61","author":"Roby","year":"1999","journal-title":"Biol Reprod"},{"key":"2020071611592878700_R804","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1242\/dev.01056","article-title":"PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.","volume":"131","author":"Salustri","year":"2004","journal-title":"Development"},{"key":"2020071611592878700_R805","doi-asserted-by":"crossref","first-page":"4287","DOI":"10.1242\/dev.00650","article-title":"GP130, the shared receptor for the LIF\/IL6 cytokine family in the mouse, is not required for early germ cell differentiation, but is required cell-autonomously in oocytes for ovulation.","volume":"130","author":"Molyneaux","year":"2003","journal-title":"Development"},{"key":"2020071611592878700_R806","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1210\/endo.139.6.6054","article-title":"The role of nitric oxide in oocyte meiotic maturation and ovulation: meiotic abnormalities of endothelial nitric oxide synthase knock-out mouse oocytes.","volume":"139","author":"Jablonka-Shariff","year":"1998","journal-title":"Endocrinology"},{"key":"2020071611592878700_R807","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.1128\/MCB.25.11.4615-4624.2005","article-title":"Mice deficient in oocyte-specific oligoadenylate synthase-like protein, OAS1D display reduced fertility.","volume":"25","author":"Yan","year":"2005","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R808","doi-asserted-by":"crossref","first-page":"11998","DOI":"10.1073\/pnas.96.21.11998","article-title":"Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D- deficient mice.","volume":"96","author":"Jin","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R809","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1128\/MCB.23.1.38-54.2003","article-title":"The mammalian SIR2\u03b1 protein has a role in embryogenesis and gametogenesis.","volume":"23","author":"McBurney","year":"2003","journal-title":"Mol Cell Biol"},{"key":"2020071611592878700_R810","doi-asserted-by":"crossref","first-page":"5342","DOI":"10.1210\/endo.142.12.8540","article-title":"Targeted disruption of the mouse estrogen sulfotransferase gene reveals a role of estrogen metabolism in intracrine and paracrine estrogen regulation.","volume":"142","author":"Qian","year":"2001","journal-title":"Endocrinology"},{"key":"2020071611592878700_R811","doi-asserted-by":"crossref","first-page":"5755","DOI":"10.1073\/pnas.0408718102","article-title":"Absence of the DNA-\/RNA-binding protein MSY2 results in male and female infertility.","volume":"102","author":"Yang","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"2020071611592878700_R812","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1210\/en.2009-0214","article-title":"Phospholipase C-\u03b21 signaling affects reproductive behavior, ovulation, and implantation.","volume":"150","author":"Filis","year":"2009","journal-title":"Endocrinology"},{"key":"2020071611592878700_R813","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1210\/mend.12.1.0049","article-title":"Multiple pituitary and ovarian defects in Krox-24 (NGFI-A, Egr-1)-targeted mice.","volume":"12","author":"Topilko","year":"1998","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R814","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1126\/science.273.5279.1219","article-title":"Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1).","volume":"273","author":"Lee","year":"1996","journal-title":"Science"},{"key":"2020071611592878700_R815","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1210\/mend.15.6.0644","article-title":"Puromycin-sensitive aminopeptidase is essential for the maternal recognition of pregnancy in mice.","volume":"15","author":"Osada","year":"2001","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R816","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1126\/science.277.5326.681","article-title":"Failure of parturition in mice lacking the prostaglandin F receptor.","volume":"277","author":"Sugimoto","year":"1997","journal-title":"Science"},{"key":"2020071611592878700_R817","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1210\/endo.142.8.8320","article-title":"Ovarian pathology and high incidence of sex cord tumors in follitropin receptor knockout (FORKO) mice.","volume":"142","author":"Danilovich","year":"2001","journal-title":"Endocrinology"},{"key":"2020071611592878700_R818","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1210\/me.2003-0154","article-title":"Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1.","volume":"17","author":"Bertolino","year":"2003","journal-title":"Mol Endocrinol"},{"key":"2020071611592878700_R819","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/ijc.22288","article-title":"Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1.","volume":"120","author":"Loffler","year":"2007","journal-title":"Int J Cancer"},{"key":"2020071611592878700_R820","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/ijc.24057","article-title":"Global expression profiling of sex cord stromal tumors from Men1 heterozygous mice identifies altered TGF-\u03b2 signaling, decreased Gata6 and increased Csf1r expression.","volume":"124","author":"Mould","year":"2009","journal-title":"Int J Cancer"},{"key":"2020071611592878700_R821","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S1071-5576(03)00073-X","article-title":"Generation of tumors in transgenic mice expressing the SV40 T antigen under the control of ovarian-specific promoter 1.","volume":"10","author":"Garson","year":"2003","journal-title":"J Soc Gynecol Investig"},{"key":"2020071611592878700_R822","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/s003359900052","article-title":"Ovarian teratomas associated with the insertion of an imprinted transgene.","volume":"7","author":"Fafalios","year":"1996","journal-title":"Mamm Genome"},{"key":"2020071611592878700_R823","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.mce.2004.10.013","article-title":"Multiple sites of tumorigenesis in transgenic mice overproducing hCG.","volume":"234","author":"Huhtaniemi","year":"2005","journal-title":"Mol Cell Endocrinol"}],"container-title":["Endocrine Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/edrv\/article-pdf\/30\/6\/624\/10334763\/edrv0624.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/edrv\/article-pdf\/30\/6\/624\/10334763\/edrv0624.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T13:25:15Z","timestamp":1739366715000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/edrv\/article\/30\/6\/624\/2355078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,1]]},"references-count":823,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/er.2009-0012","relation":{},"ISSN":["0163-769X","1945-7189"],"issn-type":[{"value":"0163-769X","type":"print"},{"value":"1945-7189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,1]]}}}