{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:16:12Z","timestamp":1793333772658,"version":"4.5.0"},"reference-count":39,"publisher":"The Endocrine Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,5,1]]},"abstract":"<jats:p>Subacute thyroiditis (SAT), or granulomatous thyroiditis, is an inflammatory thyroid condition associated with pain and systemic symptoms. Few community studies are available. We studied the 160 patients with SAT in Olmsted County, Minnesota, seen between January 1, 1960, and December 30, 1997. Subjects were identified through the medical diagnostic index of the Rochester Epidemiology Project. The overall age- and sex-adjusted incidence from 1960 through 1997 was 4.9 cases per 100,000\/yr. In the most recent 28-yr period (1970\u20131997), 94 patients were identified. In this group, pain was the presenting symptom in 96%. SAT recurred in 4% of the patients 6\u201321 yr after the initial episode. Corticosteroid therapy was given to 36%. Early-onset hypothyroidism occurred both in patients receiving corticosteroid therapy (29%) and in those not receiving corticosteroid therapy (37%). At latest follow-up, significantly more patients who had received corticosteroid therapy had a diagnosis of hypothyroidism than the group without corticosteroid therapy (25% vs. 10%, P &amp;lt; 0.05; overall rate of hypothyroidism, 15%). Early transient hypothyroidism is common in SAT. Permanent hypothyroidism is less common, and only 15% of the patients are receiving T4 therapy after 28 yr of follow-up. Symptomatic relief is achieved with corticosteroid therapy, but such therapy does not prevent early- and late-onset thyroid dysfunction.<\/jats:p>","DOI":"10.1210\/jc.2002-021799","type":"journal-article","created":{"date-parts":[[2003,5,1]],"date-time":"2003-05-01T22:14:18Z","timestamp":1051827258000},"page":"2100-2105","source":"Crossref","is-referenced-by-count":331,"title":["Clinical Features and Outcome of Subacute Thyroiditis in an Incidence Cohort: Olmsted County, Minnesota, Study"],"prefix":"10.1210","volume":"88","author":[{"given":"Vahab","family":"Fatourechi","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Diabetes, Metabolism, Nutrition and Internal Medicine (V.F., J.P.A., G.Z.E.F.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslaw P.","family":"Aniszewski","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, Metabolism, Nutrition and Internal Medicine (V.F., J.P.A., G.Z.E.F.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiti Z. Eghbali","family":"Fatourechi","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, Metabolism, Nutrition and Internal Medicine (V.F., J.P.A., G.Z.E.F.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Atkinson","sequence":"additional","affiliation":[{"name":"Division of Biostatistics (E.J.A.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Division of Epidemiology (S.J.J.), Mayo Clinic, Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"2020071618582762200_R1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0300-595X(79)80011-0","article-title":"Subacute (de Quervain\u2019s) thyroiditis.","volume":"8","author":"Volpe","year":"1979","journal-title":"Clin Endocrinol Metab"},{"key":"2020071618582762200_R2","first-page":"117","article-title":"Thyroiditis.","volume":"6","author":"Walfish","year":"1997","journal-title":"Curr Ther Endocrinol Metab"},{"key":"2020071618582762200_R3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0889-8529(05)70305-4","article-title":"Syndromes of thyrotoxicosis with low radioactive iodine uptake.","volume":"27","author":"Ross","year":"1998","journal-title":"Endocrinol Metab Clin North Am"},{"key":"2020071618582762200_R4","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1097\/00003072-199304000-00007","article-title":"Clinical, laboratory, and scintigraphic manifestations of subacute and chronic thyroiditis.","volume":"18","author":"Intenzo","year":"1993","journal-title":"Clin Nucl Med"},{"key":"2020071618582762200_R5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0025-7125(16)30472-2","article-title":"Thyroiditis: acute, subacute, and chronic.","volume":"75","author":"Singer","year":"1991","journal-title":"Med Clin North Am"},{"key":"2020071618582762200_R6","first-page":"115","article-title":"Subacute thyroiditis.","volume":"74","author":"Volpe","year":"1981","journal-title":"Prog Clin Biol Res"},{"key":"2020071618582762200_R7","first-page":"1047","article-title":"Thyroiditis: differential diagnosis and management.","volume":"61","author":"Slatosky","year":"2000","journal-title":"Am Fam Physician"},{"key":"2020071618582762200_R8","doi-asserted-by":"crossref","first-page":"292","DOI":"10.2169\/internalmedicine.40.292","article-title":"Evaluation of recurrence in 36 subacute thyroiditis patients managed with prednisolone.","volume":"40","author":"Mizukoshi","year":"2001","journal-title":"Intern Med"},{"key":"2020071618582762200_R9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1097\/00003072-198906000-00010","article-title":"Subacute thyroiditis: a review of 105 cases.","volume":"14","author":"Kitchener","year":"1989","journal-title":"Clin Nucl Med"},{"key":"2020071618582762200_R10","first-page":"113","article-title":"Subacute thyroiditis\u201461 cases: review.","volume":"43","author":"Hwang","year":"1989","journal-title":"Zhonghua Yi Xue Za Zhi (Taipei)"},{"key":"2020071618582762200_R11","first-page":"687","article-title":"Cytomorphologic aspects of thyroiditis. 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