{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:51:19Z","timestamp":1761742279815},"reference-count":20,"publisher":"The Endocrine Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We reported the outcomes of computed tomography (CT)-guided percutaneous acetic acid injection therapy for functioning adrenocortical adenomas. With the patient in a prone position, the puncture needle was inserted vertically downward into the adenoma with frequent CT scanning. After confirmation by pilot injection with contrast medium, a small aliquot of 40\u201350% acetic acid was injected and repeated. Between 1997 and 2002, 18 sessions of CT-guided injection therapy, including one session of ethanol injection, were performed on 10 patients (five patients with primary aldosteronism and five patients with Cushing\u2019s or subclinical Cushing\u2019s syndrome) without any complications except transient upper abdominal pain during the acetic acid injection. The follow-up period ranged from 5\u201369 months. The treatment resulted in almost an extirpation of the adrenocortical hyperfunction in seven patients after one or two sessions. CT-guided percutaneous acetic acid injection might be a simple, cost-effective, and far less invasive treatment for small functioning adrenocortical adenomas.<\/jats:p>","DOI":"10.1210\/jc.2003-030530","type":"journal-article","created":{"date-parts":[[2003,12,11]],"date-time":"2003-12-11T22:23:51Z","timestamp":1071181431000},"page":"5814-5817","source":"Crossref","is-referenced-by-count":15,"title":["Computed Tomography-Guided Percutaneous Acetic Acid Injection Therapy for Functioning Adrenocortical Adenoma"],"prefix":"10.1210","volume":"88","author":[{"given":"Shigeru","family":"Minowada","sequence":"first","affiliation":[{"name":"Departments of Urology (S.M., T.F., H.K.), Tokyo 162-8655, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Fujimura","sequence":"additional","affiliation":[{"name":"Departments of Urology (S.M., T.F., H.K.), Tokyo 162-8655, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Radiology (N.T., K.H.), International Medical Center of Japan, Tokyo 162-8655, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroichi","family":"Kishi","sequence":"additional","affiliation":[{"name":"Departments of Urology (S.M., T.F., H.K.), Tokyo 162-8655, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanehiro","family":"Hasuo","sequence":"additional","affiliation":[{"name":"Departments of Urology (S.M., T.F., H.K.), Tokyo 162-8655, Japan"},{"name":"Radiology (N.T., K.H.), International Medical Center of Japan, Tokyo 162-8655, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Minami","sequence":"additional","affiliation":[{"name":"Department of Radiology (M.M.), Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","reference":[{"key":"2020071616563409200_R1","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/j.1440-1746.1990.tb01115.x","article-title":"Percutaneous ethanol injection for the treatment of small hepatocellular carcinoma: study of 95 patients.","volume":"5","author":"Ebara","year":"1990","journal-title":"J Gastroenterol Hepatol"},{"key":"2020071616563409200_R2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1148\/radiology.197.1.7568806","article-title":"Hepatocellular carcinoma and cirrhosis in 746 patients: long-term results of percutaneous ethanol injection.","volume":"197","author":"Livraghi","year":"1995","journal-title":"Radiology"},{"key":"2020071616563409200_R3","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1530\/eje.0.1360240","article-title":"Percutaneous ethanol injection therapy in the treatment of thyroid and parathyroid diseases.","volume":"136","author":"Bennedbc\u0301k","year":"1997","journal-title":"Eur J Endocrinol"},{"key":"2020071616563409200_R4","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.1210\/jcem.83.11.5257","article-title":"Treatment of large cold benign thyroid nodules not eligible for surgery with percutaneous ethanol injection.","volume":"83","author":"Zingrillo","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"2020071616563409200_R5","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/hep.510270112","article-title":"Prospective randomized controlled trial comparing percutaneous acetic acid injection and percutaneous ethanol injection for small hepatocellular carcinoma.","volume":"27","author":"Ohnishi","year":"1998","journal-title":"Hepatology"},{"key":"2020071616563409200_R6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/01.SLA.0000048443.71734.BF","article-title":"Percutaneous local ablative therapy for hepatocellular carcinoma. 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