{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T23:40:00Z","timestamp":1781566800888,"version":"3.54.5"},"reference-count":42,"publisher":"The Endocrine Society","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,11,1]]},"DOI":"10.1210\/jc.2003-030956","type":"journal-article","created":{"date-parts":[[2003,11,6]],"date-time":"2003-11-06T13:11:05Z","timestamp":1068124265000},"page":"5387-5391","source":"Crossref","is-referenced-by-count":35,"title":["Opposite Changes in Circulating Adiponectin in Women With Bulimia Nervosa or Binge Eating Disorder"],"prefix":"10.1210","volume":"88","author":[{"given":"Palmiero","family":"Monteleone","sequence":"first","affiliation":[{"name":"Departments of Psychiatry (P.M., M.F., V.M., A.F., C.S., M.M.), 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Fabrazzo","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry (P.M., M.F., V.M., A.F., C.S., M.M.), 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassilis","family":"Martiadis","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry (P.M., M.F., V.M., A.F., C.S., M.M.), 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Fuschino","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry (P.M., M.F., V.M., A.F., C.S., M.M.), 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Serritella","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry (P.M., M.F., V.M., A.F., C.S., M.M.), 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Milici","sequence":"additional","affiliation":[{"name":"Biochemistry and Biophysics (N.M.), University of Naples SUN, 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Maj","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry (P.M., M.F., V.M., A.F., C.S., M.M.), 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114143496000_R1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1079\/PNS200194","article-title":"Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ.","volume":"60","author":"Trayhum","year":"2001","journal-title":"Proc Nutr Soc"},{"key":"key\n\t\t\t\t2019041114143496000_R2","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S1043-2760(01)00524-0","article-title":"ACRP30\/adiponectin: an adipokine regulating glucose and lipid metabolism.","volume":"13","author":"Berg","year":"2002","journal-title":"Trends Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114143496000_R3","first-page":"947","article-title":"The adipocyte-secreted protein Acrp30 enhances hepatic insulin action.","volume":"7","author":"Berg","year":"2001","journal-title":"Nat Med 2001"},{"key":"key\n\t\t\t\t2019041114143496000_R4","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1161\/01.CIR.102.11.1296","article-title":"Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-\u03baB signaling trough a cAMP-dependent pathway.","volume":"102","author":"Ouchi","year":"2000","journal-title":"Circulation"},{"key":"key\n\t\t\t\t2019041114143496000_R5","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1073\/pnas.98.4.2005","article-title":"Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice.","volume":"98","author":"Fruebis","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t2019041114143496000_R6","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/90984","article-title":"The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.","volume":"7","author":"Yamauchi","year":"2001","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t2019041114143496000_R7","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/bbrc.1999.0255","article-title":"Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.","volume":"257","author":"Arita","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114143496000_R8","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1161\/01.ATV.20.6.1595","article-title":"Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.","volume":"20","author":"Hotta","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key\n\t\t\t\t2019041114143496000_R9","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.2337\/diabetes.50.5.1126","article-title":"Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys.","volume":"50","author":"Hotta","year":"2001","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114143496000_R10","doi-asserted-by":"crossref","first-page":"2764","DOI":"10.1210\/jcem.87.6.8550","article-title":"Decreased plasma adiponectin concentration in women with dyslipidemia.","volume":"87","author":"Matsubara","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114143496000_R11","first-page":"355","article-title":"Metabolic and endocrine investigations in women of normal weight with the bulimia syndrome.","volume":"18","author":"Mitchell","year":"1983","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t2019041114143496000_R12","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S0026-0495(97)90181-5","article-title":"Intravenous glucose tolerance test-derived glucose effectiveness in bulimia nervosa.","volume":"46","author":"Taniguchi","year":"1997","journal-title":"Metabolism"},{"key":"key\n\t\t\t\t2019041114143496000_R13","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0006-3223(89)90248-5","article-title":"The effect of bingeing and vomiting on hormonal secretion.","volume":"25","author":"Kaye","year":"1989","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t2019041114143496000_R14","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/1098-108X(198707)6:4<551::AID-EAT2260060412>3.0.CO;2-7","article-title":"Altered insulin responses to a balanced test meal in bulimic patients.","volume":"6","author":"Schweiger","year":"1986","journal-title":"Int J Eat Disord"},{"key":"key\n\t\t\t\t2019041114143496000_R15","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1600-0447.1990.tb06487.x","article-title":"Insulin sensitivity in patients with anorexia and bulimia.","volume":"81","author":"Kiriike","year":"1990","journal-title":"Acta Psychiatr Scand"},{"key":"key\n\t\t\t\t2019041114143496000_R16","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/(SICI)1098-108X(199611)20:3<307::AID-EAT10>3.0.CO;2-X","article-title":"Insulin response in bulimia nervosa as a marker of nutritional depletion.","volume":"20","author":"Russell","year":"1996","journal-title":"Int J Eat Disord"},{"key":"key\n\t\t\t\t2019041114143496000_R17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1177\/000456328702400104","article-title":"Biochemical abnormalities in anorexia and bulimia.","volume":"24","author":"Mira","year":"1987","journal-title":"Ann Clin Biochem"},{"key":"key\n\t\t\t\t2019041114143496000_R18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/1098-108X(199404)15:3<293::AID-EAT2260150315>3.0.CO;2-U","article-title":"Hypercholesterolemia in bulimia nervosa.","volume":"15","author":"Vize","year":"1994","journal-title":"Int J Eat Disord"},{"key":"key\n\t\t\t\t2019041114143496000_R19","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/(SICI)1098-108X(199805)23:4<425::AID-EAT10>3.0.CO;2-V","article-title":"Elevated total cholesterol in bulimia nervosa.","volume":"23","author":"Sullivan","year":"1998","journal-title":"Int J Eat Disord"},{"key":"key\n\t\t\t\t2019041114143496000_R20","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/eat.1087","article-title":"Serum cholesterol in bulimia nervosa.","volume":"30","author":"Pauporte","year":"2001","journal-title":"Int J Eat Disord"},{"key":"key\n\t\t\t\t2019041114143496000_R21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/(SICI)1098-108X(199903)25:2<187::AID-EAT8>3.0.CO;2-9","article-title":"Elevated plasma lipids in patients with binge eating disorders are found only in those who are anorexic.","volume":"25","author":"Case","year":"1999","journal-title":"Int J Eat Disord"},{"key":"key\n\t\t\t\t2019041114143496000_R22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S1471-0153(01)00028-9","article-title":"Disordered eating behaviours in women with type 2 diabetes mellitus.","volume":"2","author":"Kenardy","year":"2001","journal-title":"Eat Behav"},{"key":"key\n\t\t\t\t2019041114143496000_R23","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0165-1781(00)00144-X","article-title":"Circulating leptin in patients with anorexia nervosa, bulimia nervosa or binge-eating disorder: relationship to body weight, eating patterns, psychopathology and endocrine changes.","volume":"94","author":"Monteleone","year":"2000","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t2019041114143496000_R24","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/sj.mp.4001043","article-title":"Opposite modifications in circulating leptin and soluble leptin receptor across the eating disorder spectrum.","volume":"7","author":"Monteleone","year":"2002","journal-title":"Mol Psychiatry"},{"key":"key\n\t\t\t\t2019041114143496000_R25","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1210\/jcem.85.7.6673","article-title":"Plasma leptin response to acute fasting and refeeding in untreated women with bulimia nervosa.","volume":"85","author":"Monteleone","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114143496000_R26","first-page":"4511","article-title":"Decreased serum leptin in bulimia nervosa.","volume":"85","author":"Jimerson","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114143496000_R27","volume-title":"Diagnostic and statistical manual of mental disorders, 4th ed","year":"1990"},{"key":"key\n\t\t\t\t2019041114143496000_R28"},{"key":"key\n\t\t\t\t2019041114143496000_R29","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0924-9338(97)83296-8","article-title":"The Mini International Neuropsychiatric Interview (M.I.N.I.). A short diagnostic structured interview: reliability and validity according to the CIDI.","volume":"12","author":"Lecrubier","year":"1997","journal-title":"Eur Psychiatry"},{"key":"key\n\t\t\t\t2019041114143496000_R30","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1001\/archpsyc.1977.01770220111013","article-title":"The family history method using diagnostic criteria: reliability and validity.","volume":"34","author":"Andreasen","year":"1997","journal-title":"Arch Gen Psychiatry"},{"key":"key\n\t\t\t\t2019041114143496000_R31","volume-title":"BMDP statistical software","author":"Dixon","year":"1985"},{"key":"key\n\t\t\t\t2019041114143496000_R32","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1001\/archinte.1988.00380010040006","article-title":"Report of the National Cholesterol Education Program Expert Panel on the detection, evaluation, treatment of high blood cholesterol in adults.","volume":"148","year":"1988","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t2019041114143496000_R33","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1530\/eje.0.1470173","article-title":"Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese woman.","volume":"147","author":"Matsubara","year":"2002","journal-title":"Eur J Endocrinol"},{"key":"key\n\t\t\t\t2019041114143496000_R34","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1006\/bbrc.2001.5904","article-title":"Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue.","volume":"288","author":"Halleux","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114143496000_R35","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1046\/j.1365-2265.2003.01702.x","article-title":"Hyperadiponectinaemia in anorexia nervosa.","volume":"58","author":"Delporte","year":"2003","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114143496000_R36","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1210\/jc.2002-021215","article-title":"Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism.","volume":"88","author":"Pannacciulli","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114143496000_R37","first-page":"139","article-title":"Physical complications and physiological aberrations in eating disorders: a review","author":"Brambilla","year":"2003","journal-title":"In: Maj M, Halmi K, Lo\u0300pez-Ibor JJ, Sartorius N, eds. Eating disorders. Hoboken, NJ: John Wiley & Sons Ltd.;"},{"key":"key\n\t\t\t\t2019041114143496000_R38","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/00006842-200101000-00008","article-title":"Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa.","volume":"63","author":"Monteleone","year":"2001","journal-title":"Psychosom Med"},{"key":"key\n\t\t\t\t2019041114143496000_R39"},{"key":"key\n\t\t\t\t2019041114143496000_R40","first-page":"428","article-title":"Impact of binge eating on metabolic and leptin dynamics in normal young women.","volume":"84","author":"Taylor","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114143496000_R41","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2337\/diacare.17.10.1197","article-title":"A comparison of eating behaviors in newly diagnosed non-insulin-dependent diabetes mellitus and case-matched controls.","volume":"17","author":"Kenardy","year":"1994","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114143496000_R42","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.2337\/diacare.21.7.1110","article-title":"Does diabetes control reflect disturbed eating behavior?","volume":"21","author":"Herpertz","year":"1998","journal-title":"Diabetes Care"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/88\/11\/5387\/9062780\/jcem5387.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T15:56:09Z","timestamp":1585238169000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/88\/11\/5387\/2656686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,1]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2003,11,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2003-030956","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,11,1]]}}}