{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:47:03Z","timestamp":1787021223874,"version":"build-2736575974"},"reference-count":33,"publisher":"The Endocrine Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,7,1]]},"DOI":"10.1210\/jc.2005-2115","type":"journal-article","created":{"date-parts":[[2006,4,11]],"date-time":"2006-04-11T21:34:11Z","timestamp":1144791251000},"page":"2755-2760","source":"Crossref","is-referenced-by-count":104,"title":["High Plasma Resistin Level Is Associated with Enhanced Highly Sensitive C-Reactive Protein and Leukocytes"],"prefix":"10.1210","volume":"91","author":[{"given":"Anne","family":"Kunnari","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Biocenter Oulu (A.K., O.U., Y.A.K.) Oulu, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olavi","family":"Ukkola","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Biocenter Oulu (A.K., O.U., Y.A.K.) Oulu, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markku","family":"Pa\u0308iva\u0308nsalo","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology (M.P.), 90014 University of Oulu, Oulu, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. Antero","family":"Kesa\u0308niemi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Biocenter Oulu (A.K., O.U., Y.A.K.) Oulu, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114180823900_R1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/35053000","article-title":"The hormone resistin links obesity to diabetes","volume":"409","author":"Steppan","year":"2001","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019041114180823900_R2","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.bbrc.2003.09.093","article-title":"Comparative studies of resistin expression and phylogenomics in human and mouse","volume":"310","author":"Yang","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114180823900_R3","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0006-291X(02)02841-3","article-title":"Resistin is expressed in human macrophages and directly regulated by PPAR\u03b3 activators","volume":"300","author":"Patel","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114180823900_R4","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1055\/s-2002-38241","article-title":"Plasma resistin levels in patients with type 1 and type 2 diabetes mellitus and in healthy controls","volume":"34","author":"Fehmann","year":"2002","journal-title":"Horm Metab Res"},{"key":"key\n\t\t\t\t2019041114180823900_R5","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1210\/jc.2003-030519","article-title":"Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects","volume":"88","author":"Lee","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114180823900_R6","doi-asserted-by":"crossref","first-page":"6098","DOI":"10.1210\/jc.2003-030898","article-title":"Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes","volume":"88","author":"McTernan","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114180823900_R7","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1210\/jc.2003-031121","article-title":"Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus","volume":"89","author":"Youn","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114180823900_R8","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1210\/jc.2002-021604","article-title":"Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans","volume":"88","author":"Yannakoulia","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114180823900_R9","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.cccn.2003.09.009","article-title":"Enzyme-linked immunosorbent assay for circulating human resistin: resistin concentrations in normal subjects and patients with type 2 diabetes","volume":"339","author":"Fujinami","year":"2004","journal-title":"Clin Chim Acta"},{"key":"key\n\t\t\t\t2019041114180823900_R10","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.2337\/diabetes.53.5.1279","article-title":"High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians","volume":"53","author":"Volarova de Courten","year":"2004","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114180823900_R11","doi-asserted-by":"crossref","first-page":"63","DOI":"10.5507\/bp.2003.009","article-title":"Resistin\u2014concentrations in persons with type 2 diabetes mellitus and in individuals with acute inflammatory disease","volume":"147","author":"Stejskal","year":"2003","journal-title":"Biomed Papers"},{"key":"key\n\t\t\t\t2019041114180823900_R12","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0014-5793(02)03450-6","article-title":"Lipopolysaccharide increases resistin gene expression in vivo an in vitro","volume":"530","author":"Lu","year":"2002","journal-title":"FEBS Lett"},{"key":"key\n\t\t\t\t2019041114180823900_R13","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.bbrc.2003.07.003","article-title":"Resistin messenger-RNA expression is increased by proinflammatory cytokines in vitro","volume":"309","author":"Kaser","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114180823900_R14","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1371\/journal.pmed.0010045","article-title":"An inflammatory cascade leading to hyperresistinemia in humans","volume":"1","author":"Lehrke","year":"2004","journal-title":"PLoS Med"},{"key":"key\n\t\t\t\t2019041114180823900_R15","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1161\/01.CIR.0000084503.91330.49","article-title":"Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction","volume":"108","author":"Verma","year":"2003","journal-title":"Circulation"},{"key":"key\n\t\t\t\t2019041114180823900_R16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.bbrc.2003.12.104","article-title":"Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions","volume":"314","author":"Kawanami","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114180823900_R17","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1464-5491.2005.01480.x","article-title":"Resistin polymorphisms are associated with cerebrovascular disease in Finnish type 2 diabetic patients","volume":"22","author":"Kunnari","year":"2005","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114180823900_R18","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1365-2796.1999.00429.x","article-title":"Prevalence of the metabolic syndrome in drug-treated hypertensive patients and control subjects","volume":"245","author":"Rantala","year":"1999","journal-title":"J Intern Med"},{"key":"key\n\t\t\t\t2019041114180823900_R19","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1210\/jcem.85.7.6661","article-title":"Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans","volume":"85","author":"Katz","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114180823900_R20","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1097\/00004872-199612000-00008","article-title":"Prevalence of carotid atherosclerosis in middle-aged hypertensive and control subjects. A cross-sectional systematic study with duplex ultrasound","volume":"14","author":"Pa\u0308iva\u0308nsalo","year":"1996","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t2019041114180823900_R21","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S","article-title":"Definition, diagnosis and classification of diabetes mellitus and its complications. I. Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation","volume":"15","author":"Alberti","year":"1998","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114180823900_R22","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1006\/bbrc.2001.5173","article-title":"Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle","volume":"285","author":"Nagaev","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t2019041114180823900_R23","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.2337\/diacare.27.10.2450","article-title":"Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes","volume":"27","author":"Shetty","year":"2004","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114180823900_R24","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.2337\/diabetes.52.7.1611","article-title":"A promoter genotype and oxidative stress potentially link resistin to human insulin resistance","volume":"52","author":"Smith","year":"2003","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114180823900_R25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3181\/00379727-216-44182","article-title":"Insulin-like growth factor binding protein-1: recent findings and new directions","volume":"216","author":"Lee","year":"1997","journal-title":"Proc Soc Exp Biol Med"},{"key":"key\n\t\t\t\t2019041114180823900_R26","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1046\/j.1365-2265.2003.01789.x","article-title":"Perturbations in adiponectin, leptin and resistin levels in acromegaly: lack of correlation with insulin resistance","volume":"58","author":"Silha","year":"2003","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114180823900_R27","first-page":"761","article-title":"The insulin-like growth factor-binding protein (IGFBP) superfamily","volume":"20","author":"Hwa","year":"1999","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t2019041114180823900_R28","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-2265.2004.02000.x","article-title":"The effects of GH replacement in adult GH-deficient patients: changes in body composition without concomitant changes in the adipokines and insulin resistance","volume":"60","author":"Hana","year":"2004","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114180823900_R29","first-page":"G719","article-title":"Regulation of IGF binding protein-1 in Hep G2 cells by cytokines and reactive oxygen species","volume":"276","author":"Lang","year":"1999","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t2019041114180823900_R30","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0021-9150(00)00681-X","article-title":"The association of C-reactive protein, serum amyloid a and fibrinogen with prevalent coronary heart disease\u2014baseline findings of the PAIS project","volume":"156","author":"Jousilahti","year":"2001","journal-title":"Atherosclerosis"},{"key":"key\n\t\t\t\t2019041114180823900_R31","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1161\/01.CIR.0000155620.10387.43","article-title":"Resistin is an inflammatory marker of atherosclerosis in humans","volume":"111","author":"Reilly","year":"2005","journal-title":"Circulation"},{"key":"key\n\t\t\t\t2019041114180823900_R32","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s005479900119","article-title":"Evaluation of the association between coronary calcification detected by electron beam computed tomography and atherosclerosis of extracranial carotid arteries in vivo","volume":"7","author":"Seese","year":"1998","journal-title":"Int J Angiol"},{"key":"key\n\t\t\t\t2019041114180823900_R33","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.it.2003.10.013","article-title":"Inflammation: the link between insulin resistance, obesity and diabetes","volume":"25","author":"Dandona","year":"2004","journal-title":"Trends Immunol"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/91\/7\/2755\/9063810\/jcem2755.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T20:39:49Z","timestamp":1555533589000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/91\/7\/2755\/2656623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,1]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,7,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2005-2115","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,1]]}}}