{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:13:33Z","timestamp":1791220413946,"version":"4.1.0"},"reference-count":101,"publisher":"The Endocrine Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,10,1]]},"DOI":"10.1210\/jc.2006-0624","type":"journal-article","created":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:34:51Z","timestamp":1153269291000},"page":"3718-3724","source":"Crossref","is-referenced-by-count":235,"title":["Consequences of Fetal Exposure to Maternal Diabetes in Offspring"],"prefix":"10.1210","volume":"91","author":[{"given":"Lila-Sabrina","family":"Fetita","sequence":"first","affiliation":[{"name":"Assistance Publique-Hopitaux de Paris (L.-S.F., E.S., J.-F.G.), Department of Endocrinology and Diabetes, Saint-Louis Hospital, University Paris 7, 75475 Paris Cedex 10, France"},{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale CIC9504 (L.-S.F., E.S., F.C., J.-F.G.), University Paris 7, Assistance Publique-Hopitaux de Paris, Saint-Louis Hospital, 75475 Paris Cedex 10, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Euge\u0300ne","family":"Sobngwi","sequence":"additional","affiliation":[{"name":"Assistance Publique-Hopitaux de Paris (L.-S.F., E.S., J.-F.G.), Department of Endocrinology and Diabetes, Saint-Louis Hospital, University Paris 7, 75475 Paris Cedex 10, France"},{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale Unite\u0301 671 (E.S., J.-F.G.), Cordelier Institute of Biomedical Research, 75270 Paris Cedex 06, France"},{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale CIC9504 (L.-S.F., E.S., F.C., J.-F.G.), University Paris 7, Assistance Publique-Hopitaux de Paris, Saint-Louis Hospital, 75475 Paris Cedex 10, France"},{"name":"School of Population and Health Sciences (E.S.), Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Serradas","sequence":"additional","affiliation":[{"name":"Centre National de la Recherche Scientifique Unite\u0301 Mixte de Recherche 7059 (P.S.), Laboratory of Nutrition Physiopathology, University Paris 7, 75005 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Calvo","sequence":"additional","affiliation":[{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale CIC9504 (L.-S.F., E.S., F.C., J.-F.G.), University Paris 7, Assistance Publique-Hopitaux de Paris, Saint-Louis Hospital, 75475 Paris Cedex 10, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Franc\u0327ois","family":"Gautier","sequence":"additional","affiliation":[{"name":"Assistance Publique-Hopitaux de Paris (L.-S.F., E.S., J.-F.G.), Department of Endocrinology and Diabetes, Saint-Louis Hospital, University Paris 7, 75475 Paris Cedex 10, France"},{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale Unite\u0301 671 (E.S., J.-F.G.), Cordelier Institute of Biomedical Research, 75270 Paris Cedex 06, France"},{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale CIC9504 (L.-S.F., E.S., F.C., J.-F.G.), University Paris 7, Assistance Publique-Hopitaux de Paris, Saint-Louis Hospital, 75475 Paris Cedex 10, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114154176400_R1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1046\/j.1464-5491.2002.00675.x","article-title":"Maternal transmission of diabetes","volume":"19","author":"Alcolado","year":"2002","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114154176400_R2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/ajcn\/69.2.179","article-title":"Potential mechanisms of metabolic imprinting that lead to chronic disease","volume":"69","author":"Waterland","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"key\n\t\t\t\t2019041114154176400_R3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/dmr.5610060303","article-title":"Maternal diabetes during pregnancy: consequences for the offspring","volume":"6","author":"Aerts","year":"1990","journal-title":"Diabetes Metab Rev"},{"key":"key\n\t\t\t\t2019041114154176400_R4","doi-asserted-by":"crossref","first-page":"734","DOI":"10.2337\/diab.39.6.734","article-title":"Inheritance of diabetes mellitus as consequence of gestational hyperglycemia in rats","volume":"39","author":"Gauguier","year":"1990","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R5","doi-asserted-by":"crossref","first-page":"622","DOI":"10.2337\/diab.37.5.622","article-title":"Congenital susceptibility to NIDDM. Role of intrauterine environment","volume":"37","author":"Pettitt","year":"1988","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R6","first-page":"225","article-title":"On possible genetic and epigenetic modes of diabetes transmission","volume":"66","author":"Do\u0308rner","year":"1975","journal-title":"Endokrinologie"},{"key":"key\n\t\t\t\t2019041114154176400_R7","first-page":"121","article-title":"Further evidence for a predominantly maternal transmission of maturity-onset type diabetes","volume":"68","author":"Dorner","year":"1976","journal-title":"Endokrinologie"},{"key":"key\n\t\t\t\t2019041114154176400_R8","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0002-9378(85)90272-8","article-title":"Frequency of diabetes mellitus in mothers of probands with gestational diabetes: possible maternal influence on the predisposition to gestational diabetes","volume":"151","author":"Martin","year":"1985","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t2019041114154176400_R9","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1159\/000052916","article-title":"Maternal and paternal family history of diabetes in women with gestational diabetes or insulin-dependent diabetes mellitus type I","volume":"51","author":"Harder","year":"2001","journal-title":"Gynecol Obstet Invest"},{"key":"key\n\t\t\t\t2019041114154176400_R10","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.2337\/diacare.16.9.1262","article-title":"Differences in the prevalence of diabetes and impaired glucose tolerance according to maternal or paternal history of diabetes","volume":"16","author":"Mitchell","year":"1993","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114154176400_R11","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/(SICI)1096-9136(199605)13:5<420::AID-DIA97>3.0.CO;2-W","article-title":"Evaluation of the importance of maternal history of diabetes and of mitochondrial variation in the development of NIDDM","volume":"13","author":"McCarthy","year":"1996","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114154176400_R12","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/(SICI)1096-9136(199603)13:3<232::AID-DIA27>3.0.CO;2-7","article-title":"Familial aggregation of type 2 (non-insulin-dependent) diabetes mellitus in south India; absence of excess maternal transmission","volume":"13","author":"Viswanathan","year":"1996","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114154176400_R13","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.2337\/diabetes.48.12.2475","article-title":"Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes","volume":"48","author":"Frayling","year":"1999","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R14","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.diabres.2003.11.020","article-title":"Lack of excess maternal transmission of type 2 diabetes in a Korean population","volume":"65","author":"Kim","year":"2004","journal-title":"Diabetes Res Clin Pract"},{"key":"key\n\t\t\t\t2019041114154176400_R15","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1136\/bmj.302.6786.1178","article-title":"Importance of maternal history of non-insulin dependent diabetic patients","volume":"302","author":"Alcolado","year":"1991","journal-title":"BMJ"},{"key":"key\n\t\t\t\t2019041114154176400_R16","doi-asserted-by":"crossref","first-page":"63","DOI":"10.2337\/diab.43.1.63","article-title":"Maternal effect and familial aggregation in NIDDM. The CODIAB Study. CODIAB-INSERM-ZENECA Study Group","volume":"43","author":"Thomas","year":"1994","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R17","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.2337\/diabetes.49.12.2201","article-title":"Parental transmission of type 2 diabetes: the Framingham Offspring Study","volume":"49","author":"Meigs","year":"2000","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R18","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/oxfordjournals.aje.a112648","article-title":"Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota","volume":"108","author":"Knowler","year":"1978","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t2019041114154176400_R19","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1056\/NEJM199312303292703","article-title":"Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians","volume":"329","author":"Lillioja","year":"1993","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114154176400_R20","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2337\/diabetes.49.3.445","article-title":"Type 2 diabetes and low birth weight: the role of paternal inheritance in the association of low birth weight and diabetes","volume":"49","author":"Lindsay","year":"2000","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R21","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/(SICI)1520-6661(200001\/02)9:1<83::AID-MFM17>3.0.CO;2-O","article-title":"Effect of diabetes in pregnancy on offspring: follow-up research in the Pima Indians","volume":"9","author":"Dabelea","year":"2000","journal-title":"J Matern Fetal Med"},{"key":"key\n\t\t\t\t2019041114154176400_R22","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2337\/diabetes.55.02.06.db05-0823","article-title":"Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring","volume":"55","author":"Franks","year":"2006","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R23","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJM198302033080502","article-title":"Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy","volume":"308","author":"Pettitt","year":"1983","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114154176400_R24","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.2337\/diabetes.49.12.2208","article-title":"Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships","volume":"49","author":"Dabelea","year":"2000","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R25","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1007\/s001250050792","article-title":"Glucose tolerance and insulin secretion in children of mothers with pregestational IDDM or gestational diabetes","volume":"40","author":"Plagemann","year":"1997","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019041114154176400_R26","doi-asserted-by":"crossref","first-page":"611","DOI":"10.2337\/diacare.18.5.611","article-title":"Impaired glucose tolerance in adolescent offspring of diabetic mothers. Relationship to fetal hyperinsulinism","volume":"18","author":"Silverman","year":"1995","journal-title":"Diabetes Care"},{"issue":"Suppl 2","key":"key\n\t\t\t\t2019041114154176400_R27","first-page":"B142","article-title":"Long-term effects of the intrauterine environment","volume":"21","author":"Silverman","year":"1998","journal-title":"The Northwestern University Diabetes in Pregnancy Center. Diabetes Care"},{"key":"key\n\t\t\t\t2019041114154176400_R28","doi-asserted-by":"crossref","first-page":"905","DOI":"10.2337\/diacare.23.7.905","article-title":"Long-term follow-up of infants of mothers with type 1 diabetes: evidence for hereditary and nonhereditary transmission of diabetes and precursors","volume":"23","author":"Weiss","year":"2000","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114154176400_R29","first-page":"459","article-title":"Metabolic abnormalities in the development of non-insulin-dependent diabetes mellitus","author":"Bogardus","year":"1996","journal-title":"In: LeRoith D, Taylor SI, Olefsky JM, eds. Diabetes mellitus. Philadelphia: Lippincott-Raven;"},{"key":"key\n\t\t\t\t2019041114154176400_R30","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.2337\/diacare.27.5.1148","article-title":"Insulin sensitivity in the offspring of women with type 1 and type 2 diabetes","volume":"27","author":"Hunter","year":"2004","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114154176400_R31","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.2337\/diabetes.50.8.1828","article-title":"Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes","volume":"50","author":"Gautier","year":"2001","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R32","first-page":"160","article-title":"Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: evidence for a major-gene effect","volume":"57","author":"Hanson","year":"1995","journal-title":"Am J Hum Genet"},{"key":"key\n\t\t\t\t2019041114154176400_R33","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/S0140-6736(03)13505-2","article-title":"Effect of a diabetic environment in utero on predisposition to type 2 diabetes","volume":"361","author":"Sobngwi","year":"2003","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019041114154176400_R34","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0168-8227(97)00080-6","article-title":"The endocrine pancreas in virgin and pregnant offspring of diabetic pregnant rats","volume":"38","author":"Aerts","year":"1997","journal-title":"Diabetes Res Clin Pract"},{"issue":"Suppl 2","key":"key\n\t\t\t\t2019041114154176400_R35","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2337\/diab.40.2.S109","article-title":"Insulin secretion in adult rats after intrauterine exposure to mild hyperglycemia during late gestation","volume":"40","author":"Gauguier","year":"1991","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R36","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/0026-0495(88)90192-8","article-title":"Maternal hyperglycemia in pregnant rats: its effect on growth and carbohydrate metabolism in the offspring","volume":"37","author":"Oh","year":"1988","journal-title":"Metabolism"},{"key":"key\n\t\t\t\t2019041114154176400_R37","first-page":"E86","article-title":"Effect of gestational hyperglycemia on insulin secretion in vivo and in vitro by fetal rat pancreas","volume":"251","author":"Bihoreau","year":"1986","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t2019041114154176400_R38","doi-asserted-by":"crossref","first-page":"979","DOI":"10.2337\/diab.35.9.979","article-title":"Impaired glucose homeostasis in adult rats from hyperglycemic mothers","volume":"35","author":"Bihoreau","year":"1986","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R39","first-page":"219","article-title":"Is gestational diabetes an acquired condition?","volume":"1","author":"Aerts","year":"1979","journal-title":"J Dev Physiol"},{"key":"key\n\t\t\t\t2019041114154176400_R40","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/BF01219648","article-title":"The endocrine pancreas of the fetus from diabetic pregnant rat","volume":"15","author":"Kervran","year":"1978","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019041114154176400_R41","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/0002-9378(88)90465-6","article-title":"The diabetic intrauterine milieu has a long-lasting effect on insulin secretion by B cells and on insulin uptake by target tissues","volume":"159","author":"Aerts","year":"1988","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t2019041114154176400_R42","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1677\/joe.0.0730339","article-title":"Rat foetal endocrine pancreas in experimental diabetes","volume":"73","author":"Aerts","year":"1977","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t2019041114154176400_R43","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00500377","article-title":"Evidence for an insulin resistance in the adult offspring of pregnant streptozotocin-diabetic rats","volume":"34","author":"Holemans","year":"1991","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019041114154176400_R44","doi-asserted-by":"crossref","first-page":"530","DOI":"10.2337\/diab.42.4.530","article-title":"In vivo glucose utilization by individual tissues in virgin and pregnant offspring of severely diabetic rats","volume":"42","author":"Holemans","year":"1993","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R45","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2183\/pjab1945.51.80","article-title":"Spontaneous diabetes produced by selective breeding of normal Wistar rats","volume":"51","author":"Goto","year":"1975","journal-title":"Proc Jpn Acad"},{"key":"key\n\t\t\t\t2019041114154176400_R46","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/dmrr.566","article-title":"Programmed disorders of \u03b2 cell development and function as one cause for type 2 diabetes? The GK rat paradigm","volume":"21","author":"Portha","year":"2005","journal-title":"Diabetes Metab Res Rev"},{"key":"key\n\t\t\t\t2019041114154176400_R47","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1172\/JCI368","article-title":"Impaired pancreatic \u03b2 cell function in the fetal GK rat. Impact of diabetic inheritance","volume":"101","author":"Serradas","year":"1998","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2019041114154176400_R48","doi-asserted-by":"crossref","first-page":"220","DOI":"10.2337\/diab.43.2.220","article-title":"Higher maternal than paternal inheritance of diabetes in GK rats","volume":"43","author":"Gauguier","year":"1994","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R49","doi-asserted-by":"crossref","first-page":"281","DOI":"10.2337\/diab.43.2.281","article-title":"Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats","volume":"43","author":"Abdel-Halim","year":"1994","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R50","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1464-5491.2004.01225.x","article-title":"Is human type 2 diabetes maternally inherited? Insights from an animal model","volume":"21","author":"Gill-Randall","year":"2004","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114154176400_R51","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1007\/s00125-004-1464-x","article-title":"Type 2 diabetes mellitus\u2014genes or intrauterine environment? An embryo transfer paradigm in rats","volume":"47","author":"Gill-Randall","year":"2004","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019041114154176400_R52","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.2337\/diabetes.50.10.2279","article-title":"Intrauterine growth retardation leads to the development of type 2 diabetes in the rat","volume":"50","author":"Simmons","year":"2001","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R53","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.2337\/diabetes.51.5.1499","article-title":"Gestational diabetes leads to the development of diabetes in adulthood in the rat","volume":"51","author":"Boloker","year":"2002","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R54","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.2337\/diab.29.12.1023","article-title":"Banting Lecture 1980. Of pregnancy and progeny","volume":"29","author":"Freinkel","year":"1980","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R55","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1046\/j.1464-5491.2002.00700.x","article-title":"Congenital anomalies in the offspring of women with type 1, type 2 and gestational diabetes","volume":"19","author":"Farrell","year":"2002","journal-title":"Diabet Med"},{"key":"key\n\t\t\t\t2019041114154176400_R56","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/00008480-199908000-00014","article-title":"Diabetic embryopathy","volume":"11","author":"Kousseff","year":"1999","journal-title":"Curr Opin Pediatr"},{"key":"key\n\t\t\t\t2019041114154176400_R57","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jsgi.2005.09.007","article-title":"Advances in understanding the molecular causes of diabetes-induced birth defects","volume":"13","author":"Loeken","year":"2006","journal-title":"J Soc Gynecol Investig"},{"key":"key\n\t\t\t\t2019041114154176400_R58","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jsgi.2005.07.005","article-title":"Experimental mechanisms of diabetic embryopathy and strategies for developing therapeutic interventions","volume":"12","author":"Zhao","year":"2005","journal-title":"J Soc Gynecol Investig"},{"key":"key\n\t\t\t\t2019041114154176400_R59","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/bdra.20056","article-title":"Activation of the hexosamine pathway causes oxidative stress and abnormal embryo gene expression: involvement in diabetic teratogenesis","volume":"70","author":"Horal","year":"2004","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"key\n\t\t\t\t2019041114154176400_R60","doi-asserted-by":"crossref","first-page":"E591","DOI":"10.1152\/ajpendo.00441.2004","article-title":"Hypoxic stress in diabetic pregnancy contributes to impaired embryo gene expression and defective development by inducing oxidative stress","volume":"289","author":"Li","year":"2005","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114154176400_R61","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1056\/NEJMoa042973","article-title":"Effect of treatment of gestational diabetes mellitus on pregnancy outcomes","volume":"352","author":"Crowther","year":"2005","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114154176400_R62","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0378-3782(00)00125-0","article-title":"Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes","volume":"61","author":"Aberg","year":"2001","journal-title":"Early Hum Dev"},{"key":"key\n\t\t\t\t2019041114154176400_R63","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2337\/diabetes.49.2.225","article-title":"Early pattern of differentiation in the human pancreas","volume":"49","author":"Polak","year":"2000","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R64","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/bmb\/60.1.123","article-title":"Intra-uterine programming of the endocrine pancreas","volume":"60","author":"Fowden","year":"2001","journal-title":"Br Med Bull"},{"key":"key\n\t\t\t\t2019041114154176400_R65","first-page":"55","article-title":"[Possible contribution of hyperglycemia in utero to glucose homeostasis disorders in the adult]","author":"Ktorza","year":"1997","journal-title":"Journ Annu Diabetol Hotel Dieu"},{"key":"key\n\t\t\t\t2019041114154176400_R66","doi-asserted-by":"crossref","first-page":"392","DOI":"10.2337\/diabetes.51.2.392","article-title":"Fetal insulin-like growth factor-2 production is impaired in the GK rat model of type 2 diabetes","volume":"51","author":"Serradas","year":"2002","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R67","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/00008480-199904000-00007","article-title":"Recent advances in renal development","volume":"11","author":"Gomez","year":"1999","journal-title":"Curr Opin Pediatr"},{"key":"key\n\t\t\t\t2019041114154176400_R68","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.2337\/diabetes.48.11.2240","article-title":"Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies","volume":"48","author":"Amri","year":"1999","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R69","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.2337\/diabetes.50.5.1069","article-title":"Altered nephrogenesis due to maternal diabetes is associated with increased expression of IGF-II\/mannose-6-phosphate receptor in the fetal kidney","volume":"50","author":"Amri","year":"2001","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R70","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.2337\/diabetes.47.9.1489","article-title":"Intrauterine diabetes exposure and the risk of renal disease in diabetic Pima Indians","volume":"47","author":"Nelson","year":"1998","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R71","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s001250051681","article-title":"Intra-uterine environment influences glomerular number and the acute renal adaptation to experimental diabetes","volume":"44","author":"Jones","year":"2001","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019041114154176400_R72","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/ajh\/1.4.335","article-title":"Glomeruli and blood pressure. Less of one, more the other?","volume":"1","author":"Brenner","year":"1988","journal-title":"Am J Hypertens"},{"key":"key\n\t\t\t\t2019041114154176400_R73","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1056\/NEJMoa020549","article-title":"Nephron number in patients with primary hypertension","volume":"348","author":"Keller","year":"2003","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114154176400_R74","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1126\/science.1064344","article-title":"Induction of pancreatic differentiation by signals from blood vessels","volume":"294","author":"Lammert","year":"2001","journal-title":"Science"},{"key":"key\n\t\t\t\t2019041114154176400_R75","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0925-4773(02)00332-5","article-title":"Role of endothelial cells in early pancreas and liver development","volume":"120","author":"Lammert","year":"2003","journal-title":"Mech Dev"},{"key":"key\n\t\t\t\t2019041114154176400_R76","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/S0960-9822(03)00378-6","article-title":"Role of VEGF-A in vascularization of pancreatic islets","volume":"13","author":"Lammert","year":"2003","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t2019041114154176400_R77","doi-asserted-by":"crossref","first-page":"752","DOI":"10.2337\/diabetes.53.3.752","article-title":"Hyperglycemia-induced defects in angiogenesis in the chicken chorioallantoic membrane model","volume":"53","author":"Larger","year":"2004","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R78","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0002-9440(10)65391-6","article-title":"Hyperglycemia-induced vasculopathy in the murine vitelline vasculature: correlation with PECAM-1\/CD31 tyrosine phosphorylation state","volume":"154","author":"Pinter","year":"1999","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t2019041114154176400_R79","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S0002-9440(10)64069-2","article-title":"Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation","volume":"158","author":"Pinter","year":"2001","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t2019041114154176400_R80","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1159\/000017367","article-title":"Malformations of hypothalamic nuclei in hyperinsulinemic offspring of rats with gestational diabetes","volume":"21","author":"Plagemann","year":"1999","journal-title":"Dev Neurosci"},{"key":"key\n\t\t\t\t2019041114154176400_R81","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0304-3940(01)01495-1","article-title":"Pancreatic islet transplantation in diabetic pregnant rats prevents acquired malformation of the ventromedial hypothalamic nucleus in their offspring","volume":"299","author":"Harder","year":"2001","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t2019041114154176400_R82","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.neulet.2003.08.066","article-title":"Prevention by maternal pancreatic islet transplantation of hypothalamic malformation in offspring of diabetic mother rats is already detectable at weaning","volume":"352","author":"Harder","year":"2003","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t2019041114154176400_R83","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1515\/JPM.2004.055","article-title":"\u201cFetal programming\u201d and \u201cfunctional teratogenesis\u201d: on epigenetic mechanisms and prevention of perinatally acquired lasting health risks","volume":"32","author":"Plagemann","year":"2004","journal-title":"J Perinat Med"},{"key":"key\n\t\t\t\t2019041114154176400_R84","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3181\/00379727-194-43080","article-title":"Impaired insulin secretion in the neonatal rhesus monkey after chronic hyperinsulinemia in utero","volume":"194","author":"Susa","year":"1990","journal-title":"Proc Soc Exp Biol Med"},{"key":"key\n\t\t\t\t2019041114154176400_R85","first-page":"265","article-title":"Persistence of impaired insulin secretion in infant rhesus monkeys that had been hyperinsulinemic in utero","volume":"75","author":"Susa","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114154176400_R86","first-page":"38","article-title":"Programming by early nutrition in man","author":"Lucas","year":"1991","journal-title":"In: Bock G, Whelan J. eds. The childhood environment, and adult disease. CIBA fundation Symposium. Chichester, UK: John Wiley;"},{"key":"key\n\t\t\t\t2019041114154176400_R87","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF00399095","article-title":"Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth","volume":"36","author":"Barker","year":"1993","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019041114154176400_R88","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1375\/twin.4.5.307","article-title":"Imprinting of genes and the Barker hypothesis","volume":"4","author":"Young","year":"2001","journal-title":"Twin Res"},{"key":"key\n\t\t\t\t2019041114154176400_R89","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/0092-8674(91)90513-X","article-title":"Parental imprinting of the mouse insulin-like growth factor II gene","volume":"64","author":"DeChiara","year":"1991","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019041114154176400_R90","first-page":"145","article-title":"Igf2 imprinting in development and disease","volume":"44","author":"Reik","year":"2000","journal-title":"Int J Dev Biol"},{"key":"key\n\t\t\t\t2019041114154176400_R91","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2337\/diabetes.50.1.199","article-title":"Evidence that insulin is imprinted in the human yolk sac","volume":"50","author":"Moore","year":"2001","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R92","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/372464a0","article-title":"Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2\/Mpr gene","volume":"372","author":"Wang","year":"1994","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019041114154176400_R93","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1136\/jmg.39.12.872","article-title":"Transient neonatal diabetes, a disorder of imprinting","volume":"39","author":"Temple","year":"2002","journal-title":"J Med Genet"},{"key":"key\n\t\t\t\t2019041114154176400_R94","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.2337\/diabetes.49.8.1359","article-title":"Transient neonatal diabetes: widening the understanding of the etiopathogenesis of diabetes","volume":"49","author":"Temple","year":"2000","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R95","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1172\/JCI200419876","article-title":"Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM","volume":"114","author":"Ma","year":"2004","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2019041114154176400_R96","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.2337\/diacare.25.12.2287","article-title":"Intrauterine hyperglycemia is associated with an earlier diagnosis of diabetes in HNF-1\u03b1 gene mutation carriers","volume":"25","author":"Stride","year":"2002","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114154176400_R97","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.2337\/diabetes.53.10.2719","article-title":"Kir6.2 mutations are a common cause of permanent neonatal diabetes in a large cohort of French patients","volume":"53","author":"Vaxillaire","year":"2004","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114154176400_R98","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1056\/NEJM200105243442104","article-title":"Neonatal diabetes mellitus due to complete glucokinase deficiency","volume":"344","author":"Njolstad","year":"2001","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114154176400_R99","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1262-3636(07)70025-3","article-title":"Marital status and family size of type 1 diabetic patients in a French cohort","volume":"29","author":"Sobngwi","year":"2003","journal-title":"Diabetes Metab"},{"issue":"Suppl 1","key":"key\n\t\t\t\t2019041114154176400_R100","doi-asserted-by":"crossref","first-page":"S76","DOI":"10.2337\/diacare.27.2007.S76","article-title":"Preconception care of women with diabetes","volume":"27","author":"American Diabetes Association","year":"2004","journal-title":"Diabetes Care"},{"issue":"Suppl 2","key":"key\n\t\t\t\t2019041114154176400_R101","first-page":"B161","article-title":"Summary and recommendations of the Fourth International Workshop-Conference on Gestational Diabetes Mellitus","volume":"21","author":"Metzger","year":"1998","journal-title":"The Organizing Committee. Diabetes Care"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/91\/10\/3718\/9059608\/jcem3718.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T04:11:30Z","timestamp":1683519090000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/91\/10\/3718\/2656251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,1]]},"references-count":101,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2006-0624","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,1]]}}}