{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T04:16:20Z","timestamp":1778991380303,"version":"3.51.4"},"reference-count":43,"publisher":"The Endocrine Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,10,1]]},"DOI":"10.1210\/jc.2006-0684","type":"journal-article","created":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T23:23:50Z","timestamp":1152660230000},"page":"3835-3843","source":"Crossref","is-referenced-by-count":62,"title":["Pamidronate Reduces Bone Loss after Allogeneic Stem Cell Transplantation"],"prefix":"10.1210","volume":"91","author":[{"given":"A. P.","family":"Grigg","sequence":"first","affiliation":[{"name":"Royal Melbourne Hospital (A.P.G., P.S., J.S., P.R.E.), Parkville, Victoria 3050, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Shuttleworth","sequence":"additional","affiliation":[{"name":"Royal Melbourne Hospital (A.P.G., P.S., J.S., P.R.E.), Parkville, Victoria 3050, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Peter MacCallum Cancer Centre (J.R.), East Melbourne, Victoria 3002, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. P.","family":"Schwarer","sequence":"additional","affiliation":[{"name":"Alfred Hospital (A.P.S.), Prahran, Victoria 3181, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Szer","sequence":"additional","affiliation":[{"name":"Royal Melbourne Hospital (A.P.G., P.S., J.S., P.R.E.), Parkville, Victoria 3050, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Bradstock","sequence":"additional","affiliation":[{"name":"Westmead Hospital (K.B.), Westmead, New South Wales 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Hui","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital (C.H.), Adelaide 5000, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Royal Perth Hospital (R.H.), Perth, Western Australia 6000, on behalf of the Australasian Bone Marrow Transplant Cooperative Study Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R.","family":"Ebeling","sequence":"additional","affiliation":[{"name":"Royal Melbourne Hospital (A.P.G., P.S., J.S., P.R.E.), Parkville, Victoria 3050, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114024856100_R1","first-page":"339","article-title":"Bone disease after bone marrow transplantation","author":"Ebeling","year":"2005","journal-title":"In: Compston J, Shane E, eds. Bone disease of organ transplantation, Chap 19. Burlington, MA: Elsevier, Academic Press;"},{"key":"key\n\t\t\t\t2019041114024856100_R2","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1359\/jbmr.1999.14.3.342","article-title":"Mechanisms of bone loss in allogeneic and autologous hematopoietic stem cell transplantation","volume":"14","author":"Ebeling","year":"1999","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t2019041114024856100_R3","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s001980070124","article-title":"Bone loss in long-term survivors after transplantation of hematopoietic stem cells: a prospective study","volume":"11","author":"Schulte","year":"2000","journal-title":"Osteoporos Int"},{"key":"key\n\t\t\t\t2019041114024856100_R4","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1046\/j.1365-2141.2003.04303.x","article-title":"Significant and persistent loss of bone mineral density in the femoral neck after haematopoietic stem cell transplantation: long-term follow-up of a prospective study","volume":"121","author":"Gandhi","year":"2003","journal-title":"Br J Haematol"},{"key":"key\n\t\t\t\t2019041114024856100_R5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1083-8791(00)70039-5","article-title":"Mechanisms of osteoporosis after hematopoietic cell transplantation","volume":"6","author":"Weilbaecher","year":"2000","journal-title":"Biol Blood Marrow Transplant"},{"key":"key\n\t\t\t\t2019041114024856100_R6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1053\/bbmt.2001.v7.pm11400947","article-title":"Bone density loss after allogeneic hematopoietic stem cell transplantation: a prospective study","volume":"7","author":"Stern","year":"2001","journal-title":"Biol Blood Marrow Transplant"},{"key":"key\n\t\t\t\t2019041114024856100_R7","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1038\/sj.leu.2402264","article-title":"Loss of bone mass and vitamin D deficiency after hematopoietic stem cell transplantation: standard prophylactic measures fail to prevent osteoporosis","volume":"15","author":"Massenkeil","year":"2001","journal-title":"Leukemia"},{"key":"key\n\t\t\t\t2019041114024856100_R8","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1200\/JCO.2001.19.14.3306","article-title":"Ovarian failure after adjuvant chemotherapy is associated with rapid bone loss in women with early-stage breast cancer","volume":"19","author":"Shapiro","year":"2001","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019041114024856100_R9","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1002\/1097-0142(20011101)92:9<2419::AID-CNCR1591>3.0.CO;2-K","article-title":"High-dose chemotherapy shows a dose-dependent toxicity to bone marrow osteoprogenitors: a mechanism for post-bone marrow transplantation osteopenia","volume":"92","author":"Banfi","year":"2001","journal-title":"Cancer"},{"key":"key\n\t\t\t\t2019041114024856100_R10","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/S0301-472X(99)00076-4","article-title":"Stromal damage as consequence of high-dose chemo\/radiotherapy in bone marrow transplant recipients","volume":"27","author":"Galotto","year":"1999","journal-title":"Exp Hematol"},{"key":"key\n\t\t\t\t2019041114024856100_R11","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s198-002-8339-5","article-title":"The role of cytokines in the changes in bone turnover following bone marrow transplantation","volume":"13","author":"Lee","year":"2002","journal-title":"Osteoporos Int"},{"key":"key\n\t\t\t\t2019041114024856100_R12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1210\/jcem.87.1.8135","article-title":"The effect of bone marrow transplantation on the osteoblastic differentiation of human bone marrow stromal cells","volume":"87","author":"Lee","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114024856100_R13","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1359\/jbmr.2000.15.6.993","article-title":"Use of oral corticosteroids and risk of fractures","volume":"15","author":"Van Staa","year":"2000","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t2019041114024856100_R14","first-page":"1780","article-title":"Vertebral fracture risk with long-term corticosteroid therapy: prevalence and relation to age, bone density, and corticosteroid use","volume":"161","author":"Naganathan","year":"2001","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t2019041114024856100_R15","first-page":"302","volume-title":"Primer on the metabolic bone diseases and disorders of mineral metabolism","author":"Cohen","edition":"6"},{"key":"key\n\t\t\t\t2019041114024856100_R16","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/sj.bmt.1701586","article-title":"A prospective study of bone loss and turnover after allogeneic bone marrow transplantation: effect of calcium supplementation with or without calcitonin","volume":"23","author":"Valimaki","year":"1999","journal-title":"Bone Marrow Transplant"},{"key":"key\n\t\t\t\t2019041114024856100_R17","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1385\/JCD:5:3:267","article-title":"Dramatic improvement of BMD following vitamin D therapy in a bone marrow transplant recipient","volume":"5","author":"Arekat","year":"2002","journal-title":"J Clin Densitom"},{"key":"key\n\t\t\t\t2019041114024856100_R18","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/sj.bmt.1704448","article-title":"Variations in 1\u03b1,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 serum levels during allogeneic bone marrow transplantation","volume":"33","author":"Kreutz","year":"2004","journal-title":"Bone Marrow Transplant"},{"key":"key\n\t\t\t\t2019041114024856100_R19","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0378-5122(95)00991-4","article-title":"The effect of hormone replacement therapy on bone mass in patients with ovarian failure due to bone marrow transplantation","volume":"23","author":"Castelo-Branco","year":"1996","journal-title":"Maturitas"},{"key":"key\n\t\t\t\t2019041114024856100_R20","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1073\/pnas.96.1.133","article-title":"Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro","volume":"96","author":"Fisher","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t2019041114024856100_R21","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1056\/NEJM199708073370603","article-title":"Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis","volume":"337","author":"Adachi","year":"1997","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114024856100_R22","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2165\/00003495-199141020-00009","article-title":"Pamidronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease","volume":"41","author":"Fitton","year":"1991","journal-title":"Drugs"},{"key":"key\n\t\t\t\t2019041114024856100_R23","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1200\/JCO.1998.16.2.593","article-title":"Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group","volume":"16","author":"Berenson","year":"1998","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019041114024856100_R24","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1002\/jbmr.5650091002","article-title":"Universal standardization for dual x-ray absorptiometry: patient and phantom cross-calibration results","volume":"9","author":"Genant","year":"1994","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t2019041114024856100_R25","doi-asserted-by":"crossref","first-page":"3877","DOI":"10.1210\/jc.2004-2161","article-title":"Prevention of bone loss after allogeneic stem cell transplantation by calcium, vitamin D, and sex hormone replacement with or without pamidronate","volume":"90","author":"Kananen","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114024856100_R26","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.1210\/jc.2005-1079","article-title":"Is defective osteoblast function responsible for bone loss from the proximal femur despite pamidronate therapy?","volume":"90","author":"Ebeling","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114024856100_R27","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1046\/j.1523-1755.2000.00890.x","article-title":"Pamidronate therapy as prevention of bone loss following renal transplantation","volume":"57","author":"Fan","year":"2000","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t2019041114024856100_R28","first-page":"1089","article-title":"Prevention of bone loss after heart transplantation with antiresorptive therapy: a pilot study","volume":"17","author":"Shane","year":"1998","journal-title":"J Heart Lung Transplant"},{"key":"key\n\t\t\t\t2019041114024856100_R29","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1046\/j.1445-5994.2004.00551.x","article-title":"Intravenous pamidronate in the treatment and prevention of osteoporosis","volume":"34","author":"Chan","year":"2004","journal-title":"Intern Med J"},{"key":"key\n\t\t\t\t2019041114024856100_R30","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1056\/NEJMoa010845","article-title":"Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer","volume":"345","author":"Smith","year":"2001","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114024856100_R31","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1056\/NEJMoa011807","article-title":"Intravenous zoledronic acid in postmenopausal women with low bone mineral density","volume":"346","author":"Reid","year":"2002","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114024856100_R32","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/sj.bmt.1704618","article-title":"Bone metabolism in patients more than five years after bone marrow transplantation","volume":"34","author":"Kerschan-Schindl","year":"2004","journal-title":"Bone Marrow Transplant"},{"key":"key\n\t\t\t\t2019041114024856100_R33","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1007\/s00198-003-1520-2","article-title":"Beneficial treatment with risedronate in long-term survivors after allogeneic stem cell transplantation for hematological malignancies","volume":"14","author":"Tauchmanova","year":"2003","journal-title":"Osteoporos Int"},{"key":"key\n\t\t\t\t2019041114024856100_R34","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1210\/jc.2004-0509","article-title":"Short-term zoledronic acid treatment increases bone mineral density and marrow clonogenic fibroblast progenitors after allogeneic stem cell transplantation","volume":"90","author":"Tauchmanova","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114024856100_R35","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1445-5994.2006.01154.x","article-title":"Zoledronic acid prevents bone loss after allogeneic stem cell transplantation","volume":"36","author":"D\u2019Souza","year":"2006","journal-title":"Intern Med J"},{"key":"key\n\t\t\t\t2019041114024856100_R36","doi-asserted-by":"crossref","first-page":"239","DOI":"10.7326\/0003-4819-144-4-200602210-00005","article-title":"Zoledronic acid prevents bone loss after liver transplantation","volume":"144","author":"Crawford","year":"2006","journal-title":"Ann Int Med"},{"key":"key\n\t\t\t\t2019041114024856100_R37","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1056\/NEJM200304103481521","article-title":"Severe hypocalcemia after intravenous bisphosphonate therapy in occult vitamin D deficiency","volume":"348","author":"Rosen","year":"2003","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114024856100_R38","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.joms.2005.07.010","article-title":"Bisphosphonate-induced exposed bone (osteonecrosis\/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment","volume":"63","author":"Marx","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"key\n\t\t\t\t2019041114024856100_R39","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1056\/NEJMoa023110","article-title":"Bisphosphonate-induced osteopetrosis","volume":"349","author":"Whyte","year":"2003","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114024856100_R40","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1445-5994.1983.tb02676.x","article-title":"Diphosphonates and painful feet","volume":"13","author":"Evans","year":"1983","journal-title":"Aust NZ J Med"},{"key":"key\n\t\t\t\t2019041114024856100_R41","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.1200\/JCO.2001.19.14.3434","article-title":"Safety and efficacy of bisphosphonates beyond 24 months in cancer patients","volume":"19","author":"Ali","year":"2001","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019041114024856100_R42","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1002\/cncr.11373","article-title":"Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: a single center experience and a review","volume":"97","author":"Tauchmanova","year":"2003","journal-title":"Cancer"},{"key":"key\n\t\t\t\t2019041114024856100_R43","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1056\/NEJMoa035617","article-title":"Alendronate versus calcitriol for the prevention of bone loss after cardiac transplantation","volume":"350","author":"Shane","year":"2004","journal-title":"N Engl J Med"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/91\/10\/3835\/9061554\/jcem3835.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T19:58:16Z","timestamp":1555703896000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/91\/10\/3835\/2656406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,1]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2006-0684","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,1]]}}}