{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:00:37Z","timestamp":1791064837027,"version":"4.1.0"},"reference-count":36,"publisher":"The Endocrine Society","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,9,1]]},"DOI":"10.1210\/jc.2006-0736","type":"journal-article","created":{"date-parts":[[2006,7,6]],"date-time":"2006-07-06T08:53:01Z","timestamp":1152175981000},"page":"3457-3463","source":"Crossref","is-referenced-by-count":223,"title":["Insulin Sensitivity in Patients with Primary Aldosteronism: A Follow-Up Study"],"prefix":"10.1210","volume":"91","author":[{"given":"Cristiana","family":"Catena","sequence":"first","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Lapenna","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Baroselli","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Nadalini","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GianLuca","family":"Colussi","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marileda","family":"Novello","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazia","family":"Favret","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Melis","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Cavarape","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo A.","family":"Sechi","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114122181900_R1","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1172\/JCI111776","article-title":"Hyperinsulinemia: a link between hypertension, obesity and glucose intolerance","volume":"75","author":"Modan","year":"1985","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2019041114122181900_R2","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1056\/NEJM198708063170605","article-title":"Insulin resistance in essential hypertension","volume":"317","author":"Ferrannini","year":"1987","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114122181900_R3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1056\/NEJM199103143241105","article-title":"Racial differences in the relation between blood pressure and insulin resistance","volume":"324","author":"Saad","year":"1991","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114122181900_R4","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1056\/NEJM199604113341504","article-title":"Hyperinsulinemia as an independent risk factor for ischemic heart disease","volume":"334","author":"Despres","year":"1996","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114122181900_R5","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1210\/jc.2003-031337","article-title":"Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents","volume":"89","author":"Mulatero","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114122181900_R6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00004872-200402000-00006","article-title":"The challenge of more robust and reproducible methodology in screening for primary aldosteronism","volume":"22","author":"Gordon","year":"2004","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.7326\/0003-4819-135-4-200108210-00010","article-title":"Primary aldosteronism: factors associated with normalization of blood pressure after surgery","volume":"135","author":"Sawka","year":"2001","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t2019041114122181900_R8","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/ajh\/3.7.521","article-title":"Insulinemia and blood pressure: relationships in patients with primary and secondary hypertension and with and without glucose metabolism impairment","volume":"3","author":"Marigliano","year":"1990","journal-title":"Am J Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/ajh\/5.1.26","article-title":"Insulin resistance in secondary hypertension","volume":"5","author":"Shamiss","year":"1992","journal-title":"Am J Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R10","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/0026-0495(92)90019-7","article-title":"Insulin hypersecretion: a distinctive feature between essential and secondary hypertension","volume":"41","author":"Sechi","year":"1992","journal-title":"Metabolism"},{"key":"key\n\t\t\t\t2019041114122181900_R11","first-page":"755","article-title":"Does insulin resistance participate in an impaired glucose tolerance in primary aldosteronism?","volume":"8","author":"Shimamoto","year":"1994","journal-title":"J Hum Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R12","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1365-2265.1994.tb02573.x","article-title":"Increased insulin sensitivity in patients with aldosterone producing adenoma","volume":"41","author":"Ishimori","year":"1994","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114122181900_R13","doi-asserted-by":"crossref","first-page":"603","DOI":"10.33549\/physiolres.930123","article-title":"Can primary hyperaldosteronism be considered as a specific form of diabetes mellitus?","volume":"50","author":"Widimsky Jr","year":"2001","journal-title":"Physiol Res"},{"key":"key\n\t\t\t\t2019041114122181900_R14","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/sj.jhh.1001292","article-title":"Serum leptin levels in patients with primary hyperaldosteronism before and after treatment: relationships to insulin sensitivity","volume":"16","author":"Haluzik","year":"2002","journal-title":"J Hum Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R15","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1001\/jama.1997.03540450045033","article-title":"Association of serum lipoprotein(a) levels and apolipoprotein(a) size polymorphism with target-organ damage in arterial hypertension","volume":"277","author":"Sechi","year":"1997","journal-title":"JAMA"},{"key":"key\n\t\t\t\t2019041114122181900_R16","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1161\/01.HYP.36.6.978","article-title":"Relationship of fibrinogen levels and hemostatic abnormalities with organ damage in hypertension","volume":"36","author":"Sechi","year":"2000","journal-title":"Hypertension"},{"key":"key\n\t\t\t\t2019041114122181900_R17","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00004872-200402000-00023","article-title":"Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism","volume":"22","author":"Ferrari","year":"2004","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R18","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.2337\/diabetes.51.4.1226","article-title":"Abnormalities of glucose metabolism in patients with early renal failure","volume":"51","author":"Sechi","year":"2002","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t2019041114122181900_R19","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1210\/jc.2003-030087","article-title":"Insulin resistance\/compensatory hyperinsulinemia, essential hypertension, and cardiovascular disease","volume":"88","author":"Reaven","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114122181900_R20","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0140-6736(93)90135-4","article-title":"Insulin sensitivity and body fat distribution in normotensive offspring of hypertensive parents","volume":"341","author":"Allemann","year":"1993","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019041114122181900_R21","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1161\/01.HYP.20.6.797","article-title":"Fasting insulin in relation to subsequent blood pressure changes and hypertension in women","volume":"20","author":"Lissner","year":"1992","journal-title":"Hypertension"},{"key":"key\n\t\t\t\t2019041114122181900_R22","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1056\/NEJM196511182732106","article-title":"Hypertension, the potassium ion and impaired carbohydrate intolerance","volume":"273","author":"Conn","year":"1965","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114122181900_R23","first-page":"S5","article-title":"The Expert Committee on the Diagnosis and Classification on Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification on Diabetes Mellitus","volume":"26(Suppl 1)","year":"2003","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t2019041114122181900_R24","first-page":"21","article-title":"Insulin action in primary aldosteronism before and after surgical or pharmacological treatment","volume":"108","author":"Sindelka","year":"2000","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"key\n\t\t\t\t2019041114122181900_R25","doi-asserted-by":"crossref","first-page":"503","DOI":"10.33549\/physiolres.930298","article-title":"Does the treatment of primary hyperaldosteronism influence glucose tolerance","volume":"52","author":"Strauch","year":"2003","journal-title":"Physiol Res"},{"key":"key\n\t\t\t\t2019041114122181900_R26","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1210\/jc.2002-030024","article-title":"Comparison of the insulin action parameters from hyperinsulinemic clamps with homeostasis model assessment and QUICKI indexes in subjects with different endocrine disorders","volume":"89","author":"Skrha","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114122181900_R27","doi-asserted-by":"crossref","first-page":"241","DOI":"10.33549\/physiolres.930000.49.241","article-title":"Impaired insulin action in primary hyperaldosteronism","volume":"49","author":"Widimsky","year":"2000","journal-title":"Physiol Res"},{"key":"key\n\t\t\t\t2019041114122181900_R28","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1210\/jc.2005-1733","article-title":"Prevalence and characteristics of the metabolic syndrome in primary aldosteronism","volume":"91","author":"Fallo","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114122181900_R29","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1097\/01.hjh.0000222752.67572.61","article-title":"Hypertension prevalence, awareness, control and association with metabolic abnormalities in the San Marino population: the SMOOTH study","volume":"24","author":"Mancia","year":"2006","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t2019041114122181900_R30","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.amjmed.2005.09.010","article-title":"Glucose metabolism in patients with essential hypertension","volume":"119","author":"Garcia-Puig","year":"2006","journal-title":"Am J Med"},{"key":"key\n\t\t\t\t2019041114122181900_R31","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.0954-6820.1983.tb03684.x","article-title":"The effect of spironolactone on lipid, glucose and uric acid levels in blood during long-term administration to hypertensives","volume":"213","author":"Falch","year":"1983","journal-title":"Acta Med Scand"},{"key":"key\n\t\t\t\t2019041114122181900_R32","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.tem.2005.02.003","article-title":"The renin-angiotensin-aldosterone system, glucose metabolism and diabetes","volume":"3","author":"Giacchetti","year":"2005","journal-title":"Trends Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114122181900_R33","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.2337\/diabetes.49.11.1751","article-title":"Triggering and amplifying pathways of regulation of insulin secretion by glucose","volume":"49","author":"Henquin","year":"2000","journal-title":"Diabetes"},{"issue":"Suppl 2","key":"key\n\t\t\t\t2019041114122181900_R34","first-page":"26","article-title":"Hypokalemia, glucose intolerance, and hyperinsulinemia during diuretic therapy","volume":"19","author":"Plavinik","year":"1992","journal-title":"Hypertension"},{"key":"key\n\t\t\t\t2019041114122181900_R35","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s11906-003-0065-2","article-title":"The effect of aldosterone on glucose metabolism","volume":"5","author":"Corry","year":"2003","journal-title":"Curr Hypertens Rep"},{"key":"key\n\t\t\t\t2019041114122181900_R36","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1055\/s-2005-870240","article-title":"Aldosterone inhibits uncoupling protein-1, induces insulin resistance, and stimulates proinflammatory adipokines in adipocytes","volume":"37","author":"Kraus","year":"2005","journal-title":"Horm Metab Res"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/91\/9\/3457\/9063281\/jcem3457.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T19:53:25Z","timestamp":1736452405000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/91\/9\/3457\/2656598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,1]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,9,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2006-0736","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,1]]}}}