{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:37:02Z","timestamp":1791218222221,"version":"4.1.0"},"reference-count":20,"publisher":"The Endocrine Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,1,1]]},"DOI":"10.1210\/jc.2006-1748","type":"journal-article","created":{"date-parts":[[2006,10,10]],"date-time":"2006-10-10T22:53:07Z","timestamp":1160520787000},"page":"203-207","source":"Crossref","is-referenced-by-count":307,"title":["Detection of Thyroid Dysfunction in Early Pregnancy: Universal Screening or Targeted High-Risk Case Finding?"],"prefix":"10.1210","volume":"92","author":[{"given":"Bijay","family":"Vaidya","sequence":"first","affiliation":[{"name":"Department of Endocrinology (B.V., B.S.), Peninsula Medical School, Royal Devon & Exeter Hospital, Exeter EX2 5DW, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sony","family":"Anthony","sequence":"additional","affiliation":[{"name":"Departments of Endocrinology (S.A., M.B., R.B.), James Cook University Hospital, Middlesbrough TS4 3BW, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Bilous","sequence":"additional","affiliation":[{"name":"Departments of Endocrinology (S.A., M.B., R.B.), James Cook University Hospital, Middlesbrough TS4 3BW, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverley","family":"Shields","sequence":"additional","affiliation":[{"name":"Department of Endocrinology (B.V., B.S.), Peninsula Medical School, Royal Devon & Exeter Hospital, Exeter EX2 5DW, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Drury","sequence":"additional","affiliation":[{"name":"Clinical Biochemistry (J.D.), James Cook University Hospital, Middlesbrough TS4 3BW, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stewart","family":"Hutchison","sequence":"additional","affiliation":[{"name":"Obstetrics (S.H.), James Cook University Hospital, Middlesbrough TS4 3BW, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy","family":"Bilous","sequence":"additional","affiliation":[{"name":"Departments of Endocrinology (S.A., M.B., R.B.), James Cook University Hospital, Middlesbrough TS4 3BW, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114163992900_R1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJM199908193410801","article-title":"Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.","volume":"341","author":"Haddow","year":"1999","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114163992900_R2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/jms.7.3.127","article-title":"Maternal thyroid deficiency and pregnancy complications: implications for population screening.","volume":"7","author":"Allan","year":"2000","journal-title":"J Med Screen"},{"key":"key\n\t\t\t\t2019041114163992900_R3","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1046\/j.1365-2265.2003.01822.x","article-title":"Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study.","volume":"59","author":"Pop","year":"2003","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114163992900_R4","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/j.1471-0528.2004.00213.x","article-title":"Low concentrations of maternal thyroxin during early gestation: a risk factor of breech presentation?","volume":"111","author":"Pop","year":"2004","journal-title":"BJOG"},{"key":"key\n\t\t\t\t2019041114163992900_R5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/01.AOG.0000152345.99421.22","article-title":"Subclinical hypothyroidism and pregnancy outcomes.","volume":"105","author":"Casey","year":"2005","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t2019041114163992900_R6","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1001\/jama.291.2.228","article-title":"Subclinical thyroid disease: scientific review and guidelines for diagnosis and management.","volume":"291","author":"Surks","year":"2004","journal-title":"JAMA"},{"key":"key\n\t\t\t\t2019041114163992900_R7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1089\/105072503321086962","article-title":"Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease.","volume":"13","author":"Baloch","year":"2003","journal-title":"Thyroid"},{"key":"key\n\t\t\t\t2019041114163992900_R8","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1089\/thy.2005.15.44","article-title":"Are detection and treatment of thyroid insufficiency in pregnancy feasible?","volume":"15","author":"Mandel","year":"2005","journal-title":"Thyroid"},{"key":"key\n\t\t\t\t2019041114163992900_R9","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2265.1991.tb03494.x","article-title":"Prevalence of thyroid deficiency in pregnant women.","volume":"35","author":"Klein","year":"1991","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114163992900_R10","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/jc.2004-1231","article-title":"Subclinical thyroid dysfunction: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and the Endocrine Society.","volume":"90","author":"Gharib","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114163992900_R11","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1210\/jc.2004-2173","article-title":"Subclinical thyroid dysfunction\u2014can there be a consensus about the consensus?","volume":"90","author":"Ringel","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114163992900_R12","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1210\/jc.2004-1869","article-title":"Subclinical thyroid dysfunction: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and The Endocrine Society.","volume":"90","author":"Surks","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114163992900_R13","doi-asserted-by":"crossref","first-page":"599","DOI":"10.7861\/clinmedicine.2-6-599a","article-title":"Screening for thyroid disease in pregnancy: an audit.","volume":"2","author":"Vaidya","year":"2002","journal-title":"Clin Med"},{"key":"key\n\t\t\t\t2019041114163992900_R14","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1056\/NEJM199410203311608","article-title":"Maternal and fetal thyroid function.","volume":"331","author":"Burrow","year":"1994","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114163992900_R15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF03350244","article-title":"Thyroid function evaluation by different commercially available free thyroid hormone measurement kits in term pregnant women and their newborns.","volume":"14","author":"Roti","year":"1991","journal-title":"J Endocrinol Invest"},{"key":"key\n\t\t\t\t2019041114163992900_R16","first-page":"3975","article-title":"Is neuropsychological development related to maternal hypothyroidism or to maternal hypothyroxinemia?","volume":"85","author":"Morreale de Escobar","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114163992900_R17","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/S0140-6736(05)66489-6","article-title":"Maternal hypothyroxinaemia during (early) gestation.","volume":"365","author":"Pop","year":"2005","journal-title":"Lancet"},{"issue":"Suppl 3","key":"key\n\t\t\t\t2019041114163992900_R18","doi-asserted-by":"crossref","first-page":"U25","DOI":"10.1530\/eje.0.151u025","article-title":"Role of thyroid hormone during early brain development","volume":"151","author":"Morreale de Escobar","year":"2004","journal-title":"Eur J Endocrinol"},{"key":"key\n\t\t\t\t2019041114163992900_R19","doi-asserted-by":"crossref","first-page":"F436","DOI":"10.1136\/adc.2003.029306","article-title":"Prevalence of maternal dietary iodine insufficiency in the north east of England: implications for the fetus","volume":"89","author":"Kibirige","year":"2004","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"key\n\t\t\t\t2019041114163992900_R20","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1056\/NEJMoa040079","article-title":"Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism.","volume":"351","author":"Alexander","year":"2004","journal-title":"N Engl J Med"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/92\/1\/203\/11059379\/jcem0203.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T11:54:53Z","timestamp":1555847693000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/92\/1\/203\/2598479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2006-1748","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1049294.501204","asserted-by":"object"}]},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,1]]}}}