{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:12:46Z","timestamp":1792080766639,"version":"4.4.0"},"reference-count":29,"publisher":"The Endocrine Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,6,1]]},"DOI":"10.1210\/jc.2006-2350","type":"journal-article","created":{"date-parts":[[2007,4,3]],"date-time":"2007-04-03T23:56:55Z","timestamp":1175644615000},"page":"2100-2106","source":"Crossref","is-referenced-by-count":85,"title":["Letrozole Treatment of Precocious Puberty in Girls with the McCune-Albright Syndrome: A Pilot Study"],"prefix":"10.1210","volume":"92","author":[{"given":"Penelope","family":"Feuillan","sequence":"first","affiliation":[{"name":"National Human Genome Research Institute (P.F.), National Institutes of Health, Bethesda, Maryland 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Calis","sequence":"additional","affiliation":[{"name":"Clinical Center (K.C., S.H., T.S.), National Institutes of Health, Bethesda, Maryland 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvimol","family":"Hill","sequence":"additional","affiliation":[{"name":"Clinical Center (K.C., S.H., T.S.), National Institutes of Health, Bethesda, Maryland 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Shawker","sequence":"additional","affiliation":[{"name":"Clinical Center (K.C., S.H., T.S.), National Institutes of Health, Bethesda, Maryland 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela Gehron","family":"Robey","sequence":"additional","affiliation":[{"name":"National Institute of Dental and Craniofacial Research (P.G.R., M.T.C.), National Institutes of Health, Bethesda, Maryland 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael T.","family":"Collins","sequence":"additional","affiliation":[{"name":"National Institute of Dental and Craniofacial Research (P.G.R., M.T.C.), National Institutes of Health, Bethesda, Maryland 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114005637800_R1","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1056\/NEJM199112123252403","article-title":"Activating mutations of the stimulatory G protein in the McCune-Albright syndrome.","volume":"325","author":"Weinstein","year":"1991","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114005637800_R2","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1210\/jc.2003-031225","article-title":"Activating Gs\u03b1 mutations: analysis of 113 patients with signs of McCune-Albright syndrome\u2014a European collaborative study.","volume":"89","author":"Lumbroso","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R3","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1210\/jcem-59-4-801","article-title":"Variable response to a long-acting agonist of luteinizing hormone releasing hormone in girls with McCune-Albright syndrome.","volume":"59","author":"Foster","year":"1984","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R4","first-page":"647","volume":"77","author":"Feuillan","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R5","doi-asserted-by":"crossref","first-page":"5104","DOI":"10.1210\/jc.2001-012022","article-title":"Characterization of gsp-mediated growth hormone excess in the context of McCune-Albright syndrome.","volume":"87","author":"Akintoye","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R6","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/(SICI)1096-9896(199901)187:2<249::AID-PATH222>3.0.CO;2-J","article-title":"The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs\u03b1 gene: site-specific patterns and recurrent histologic hallmarks.","volume":"187","author":"Riminucci","year":"1999","journal-title":"J Pathol"},{"key":"key\n\t\t\t\t2019041114005637800_R7","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1359\/JBMR.0301262","article-title":"Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome.","volume":"19","author":"Leet","year":"2004","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t2019041114005637800_R8","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00223-001-1098-7","article-title":"Bone turnover in children and adolescents with McCune-Albright syndrome treated with pamidronate for bone fibrous dysplasia.","volume":"71","author":"Isaia","year":"2002","journal-title":"Calcif Tiss Int"},{"key":"key\n\t\t\t\t2019041114005637800_R9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1359\/JBMR.041111","article-title":"An instrument to measure skeletal burden and predict functional outcome in fibrous dysplasia of bone.","volume":"20","author":"Collins","year":"2005","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t2019041114005637800_R10","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1359\/jbmr.2001.16.5.806","article-title":"Renal phosphate wasting in fibrous dysplasia of bone is part of a generalized renal tubular dysfunction similar to that seen in tumor-induced osteomalacia.","volume":"16","author":"Collins","year":"2001","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t2019041114005637800_R11","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1056\/NEJM198808183190707","article-title":"Estrogen receptors in bone in a patient with polyostotic fibrous dysplasia (McCune-Albright syndrome).","volume":"319","author":"Kaplan","year":"1988","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114005637800_R12","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1159\/000085535","article-title":"Accelerated bone turnover in pregnant women with McCune-Albright syndrome.","volume":"60","author":"Osada","year":"2005","journal-title":"Gynecol Obstet Invest"},{"key":"key\n\t\t\t\t2019041114005637800_R13","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.1210\/jc.2003-030864","article-title":"Lack of efficacy of fadrozole in treating precocious puberty in girls with the McCune-Albright syndrome.","volume":"88","author":"Nunez","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R14","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0022-3476(03)00128-8","article-title":"Tamoxifen treatment for precocious puberty in McCune-Albright syndrome: a multicenter trial.","volume":"143","author":"Eugster","year":"2003","journal-title":"J Pediatr"},{"key":"key\n\t\t\t\t2019041114005637800_R15","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0960-0760(90)90460-3","article-title":"Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new, nonsteroidal aromatase inhibitor.","volume":"37","author":"Bhatnagar","year":"1990","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key\n\t\t\t\t2019041114005637800_R16"},{"key":"key\n\t\t\t\t2019041114005637800_R17","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1359\/jbmr.2003.18.7.1235","article-title":"Osteomalacic and hyperparathyroid changes in fibrous dysplasia of bone: core biopsy studies and clinical correlations.","volume":"18","author":"Corsi","year":"2003","journal-title":"J Bone Mineral Res"},{"key":"key\n\t\t\t\t2019041114005637800_R18","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1148\/125.2.477","article-title":"Grey scale ultrasonography of the normal female pelvis.","volume":"125","author":"Sample","year":"1977","journal-title":"Radiology"},{"key":"key\n\t\t\t\t2019041114005637800_R19","author":"Greulich","year":"1950"},{"key":"key\n\t\t\t\t2019041114005637800_R20","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0009-8981(77)90059-6","article-title":"A simple slide rule method for the assessment of renal tubular reabsorption of phosphate in man.","volume":"81","author":"Walton","year":"1977","journal-title":"Clin Chim Acta"},{"key":"key\n\t\t\t\t2019041114005637800_R21","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0378-4347(96)00118-1","article-title":"High-performance liquid chromatography of the aromatase inhibitor letrozole, and its metabolite in biological fluids with automated liquid-solid extraction and fluorescence detection.","volume":"683","author":"Marfil","year":"1996","journal-title":"J Chromatog"},{"key":"key\n\t\t\t\t2019041114005637800_R22","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/bdd.273","article-title":"Effect of age and single versus multiple dose pharmacokinetics of letrozole (Femara) in breast cancer patients.","volume":"22","author":"Pfister","year":"2001","journal-title":"Biopharm Drug Dispos"},{"key":"key\n\t\t\t\t2019041114005637800_R23","first-page":"661","article-title":"Biochemical markers of bone metabolism: application to understanding bone remodeling in children and adolescents.","volume":"16","author":"Levine","year":"2003","journal-title":"J Pediatr Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R24","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.1365-2265.2002.01573.x","article-title":"Bone metabolism markers and bone mass in healthy pubertal boys and girls.","volume":"57","author":"Van Coeverden","year":"2002","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114005637800_R25","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/j.1365-2265.1994.tb03019.x","article-title":"Biochemical markers of bone turnover in girls during puberty.","volume":"40","author":"Blumsohn","year":"1994","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041114005637800_R26","first-page":"1474","article-title":"McCune-Albright syndrome: the patterns of scintigraphic abnormalities.","volume":"31","author":"Pfeffer","year":"1990","journal-title":"J Nucl Med"},{"key":"key\n\t\t\t\t2019041114005637800_R27","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1210\/jc.2005-2661","article-title":"Pegvisomant for the treatment of gsp-mediated growth hormone excess in patients with McCune-Albright syndrome.","volume":"91","author":"Akintoye","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114005637800_R28","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.fertnstert.2005.07.1283","article-title":"A randomized trial of superovulation with two different doses of letrozole.","volume":"85","author":"Al-Fadhli","year":"2006","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019041114005637800_R29","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1093\/humrep\/deg310","article-title":"The dawning of the non-cancer uses of aromatase inhibitors in gynaecology.","volume":"18","author":"deZiegler","year":"2003","journal-title":"Hum Rep"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/92\/6\/2100\/10780301\/jcem2100.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T22:57:57Z","timestamp":1556319477000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/92\/6\/2100\/2597374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,1]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2006-2350","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,1]]}}}