{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:04:17Z","timestamp":1791813857732,"version":"4.3.4"},"reference-count":39,"publisher":"The Endocrine Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,6,1]]},"DOI":"10.1210\/jc.2012-3928","type":"journal-article","created":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T15:29:44Z","timestamp":1367422184000},"page":"2376-2382","source":"Crossref","is-referenced-by-count":195,"title":["Childhood Craniopharyngioma: Hypothalamus-Sparing Surgery Decreases the Risk of Obesity"],"prefix":"10.1210","volume":"98","author":[{"given":"E.","family":"Elowe-Gruau","sequence":"first","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Sorbonne Paris Cit\u00e9; and Centre de R\u00e9f\u00e9rence des pathologies Endocriniennes Rares de la Croissance (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Beltrand","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"},{"name":"Sorbonne Paris Cit\u00e9; and Centre de R\u00e9f\u00e9rence des pathologies Endocriniennes Rares de la Croissance (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Brauner","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Unit (R.B.), Fondation Ophtalmologique Adolphe de Rothschild, 75019 Paris, France"},{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Pinto","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Sorbonne Paris Cit\u00e9; and Centre de R\u00e9f\u00e9rence des pathologies Endocriniennes Rares de la Croissance (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Samara-Boustani","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Sorbonne Paris Cit\u00e9; and Centre de R\u00e9f\u00e9rence des pathologies Endocriniennes Rares de la Croissance (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Thalassinos","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Busiah","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"},{"name":"Sorbonne Paris Cit\u00e9; and Centre de R\u00e9f\u00e9rence des pathologies Endocriniennes Rares de la Croissance (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Laborde","sequence":"additional","affiliation":[{"name":"Functional Explorations Unit (K.L.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Boddaert","sequence":"additional","affiliation":[{"name":"Medical Imaging Department (N.B.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Zerah","sequence":"additional","affiliation":[{"name":"Pediatric Neurosurgery Unit (M.Z., C.S.-R., S.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Alapetite","sequence":"additional","affiliation":[{"name":"Radiation Oncology Unit (C.A.), Institut Curie, 75005 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Grill","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adolescent Oncology (J.G.), Gustave Roussy Oncology Institute, 94800 Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Touraine","sequence":"additional","affiliation":[{"name":"Endocrinology and Reproductive Medicine Unit (P.T.), 75013 Paris, France"},{"name":"Groupe Hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, 75013 Paris, France Pierre and Marie Curie University (P.T.); 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Sainte-Rose","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Polak","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Gynecology (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.) and Diabetology Unit, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"},{"name":"Sorbonne Paris Cit\u00e9; and Centre de R\u00e9f\u00e9rence des pathologies Endocriniennes Rares de la Croissance (E.E.-G., J.B., G.P., D.S.-B., C.T., K.B., M.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Puget","sequence":"additional","affiliation":[{"name":"Pediatric Neurosurgery Unit (M.Z., C.S.-R., S.P.), Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, 75015 Paris, France"},{"name":"Universit\u00e9 Paris Descartes (J.B., R.B., K.B., M.Z., C.S.-R., M.P., S.P.), 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041113263636800_B1","first-page":"765","article-title":"[Craniopharyngioma in children. Endocrine evaluation and treatment. Apropos of 37 cases]","volume":"44","author":"Brauner","year":"1987","journal-title":"Arch Fr Pediatr"},{"key":"key\n\t\t\t\t2019041113263636800_B2","first-page":"3","article-title":"Pediatric craniopharyngiomas: classification and treatment according to the degree of hypothalamic involvement","volume":"106","author":"Puget","year":"2007","journal-title":"J Neurosurg"},{"key":"key\n\t\t\t\t2019041113263636800_B3","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1210\/jc.2011-0174","article-title":"Consequences of craniopharyngioma surgery in children","volume":"96","author":"Muller","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B4","first-page":"163","article-title":"Treatment of craniopharyngiomas in children. Retrospective analysis of 50 cases","volume":"45","author":"Pierre-Kahn","year":"1988","journal-title":"Arch Fr Pediatr"},{"key":"key\n\t\t\t\t2019041113263636800_B5","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/s00431-010-1347-8","article-title":"Obesity, metabolic syndrome, and insulin dynamics in children after craniopharyngioma surgery","volume":"170","author":"Sahakitrungruang","year":"2011","journal-title":"Eur J Pediatr"},{"key":"key\n\t\t\t\t2019041113263636800_B6","first-page":"3897","article-title":"Postoperative prognosis in craniopharyngioma with respect to cardiovascular mortality, survival, and tumor recurrence","volume":"83","author":"Bulow","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B7","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1365-2265.2009.03639.x","article-title":"Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma","volume":"72","author":"Simoneau-Roy","year":"2010","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t2019041113263636800_B8","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00381-008-0754-x","article-title":"Craniopharyngioma and hypothalamic obesity in children","volume":"25","author":"Vinchon","year":"2009","journal-title":"Childs Nerv Syst"},{"key":"key\n\t\t\t\t2019041113263636800_B9","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1055\/s-2004-832339","article-title":"Prognosis and sequela in patients with childhood craniopharyngioma\u2014results of HIT-ENDO and update on KRANIOPHARYNGEOM 2000","volume":"216","author":"Muller","year":"2004","journal-title":"Klin Padiatr"},{"key":"key\n\t\t\t\t2019041113263636800_B10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1750-1172-2-18","article-title":"Craniopharyngioma","volume":"2","author":"Garnett","year":"2007","journal-title":"Orphanet J Rare Dis"},{"key":"key\n\t\t\t\t2019041113263636800_B11","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/ajcn\/36.1.178","article-title":"Adiposity indices in children","volume":"36","author":"Rolland-Cachera","year":"1982","journal-title":"Am J Clin Nutr"},{"key":"key\n\t\t\t\t2019041113263636800_B12","first-page":"13","article-title":"Body mass index variations: centiles from birth to 87 years","volume":"45","author":"Rolland-Cachera","year":"1991","journal-title":"Eur J Clin Nutr"},{"key":"key\n\t\t\t\t2019041113263636800_B13","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000327409","article-title":"Testing water regulation","volume-title":"Diagnostics of Endocrine Function in Children and Adolescents","author":"Czernichow","year":"2011"},{"key":"key\n\t\t\t\t2019041113263636800_B14","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1210\/jc.2002-021180","article-title":"Risk factors for the development of obesity in children surviving brain tumors","volume":"88","author":"Lustig","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B15","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1210\/jc.2011-2817","article-title":"Markers of recurrence and long-term morbidity in craniopharyngioma: a systematic analysis of 171 patients","volume":"97","author":"Gautier","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B16","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1471-2431-9-24","article-title":"Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index","volume":"9","author":"Trivin","year":"2009","journal-title":"BMC Pediatr"},{"key":"key\n\t\t\t\t2019041113263636800_B17","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1651-2227.1988.tb10705.x","article-title":"Children with craniopharyngioma. Early growth failure and rapid postoperative weight gain","volume":"77","author":"Sorva","year":"1988","journal-title":"Acta Paediatr Scand"},{"key":"key\n\t\t\t\t2019041113263636800_B18","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s003810050108","article-title":"Long-term results of treatment for craniopharyngioma in children","volume":"13","author":"Villani","year":"1997","journal-title":"Childs Nerv Syst"},{"key":"key\n\t\t\t\t2019041113263636800_B19","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/BF00395090","article-title":"Complications in paediatric craniopharyngioma treatment","volume":"12","author":"Zuccaro","year":"1996","journal-title":"Childs Nerv Syst"},{"key":"key\n\t\t\t\t2019041113263636800_B20","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s11060-010-0265-y","article-title":"Endocrinologic, neurologic, and visual morbidity after treatment for craniopharyngioma","volume":"101","author":"Sughrue","year":"2011","journal-title":"J Neurooncol"},{"key":"key\n\t\t\t\t2019041113263636800_B21","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s00381-009-0978-4","article-title":"Neurosurgical treatment strategies in childhood craniopharyngiomas: is less more?","volume":"25","author":"Schubert","year":"2009","journal-title":"Childs Nerv Syst"},{"key":"key\n\t\t\t\t2019041113263636800_B22","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000284358","article-title":"Analyses of treatment variables for patients with childhood craniopharyngioma\u2014results of the multicenter prospective trial KRANIOPHARYNGEOM 2000 after three years of follow-up","volume":"73","author":"Muller","year":"2010","journal-title":"Horm Res Paediatr"},{"key":"key\n\t\t\t\t2019041113263636800_B23","first-page":"2","article-title":"The consequences of growth hormone deficiency in adults","volume":"128","author":"Bengtsson","year":"1993","journal-title":"Acta Endocrinol (Copenh)"},{"key":"key\n\t\t\t\t2019041113263636800_B24","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/pbc.21936","article-title":"Obesity and metabolic changes are common in young childhood brain tumor survivors","volume":"52","author":"Pietila","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"key\n\t\t\t\t2019041113263636800_B25","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1016\/j.ghir.2006.03.006","article-title":"Beginning to end: cardiovascular implications of growth hormone (GH) deficiency and GH therapy","volume":"16","author":"Colao","year":"2006","journal-title":"Growth Horm IGF Res"},{"key":"key\n\t\t\t\t2019041113263636800_B26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1210\/jc.2003-030442","article-title":"Features of the metabolic syndrome after childhood craniopharyngioma","volume":"89","author":"Srinivasan","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B27","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10143-009-0220-6","article-title":"Optimal treatment strategy for craniopharyngiomas based on long-term functional outcomes of recent and past treatment modalities","volume":"33","author":"Kawamata","year":"2010","journal-title":"Neurosurg Rev"},{"key":"key\n\t\t\t\t2019041113263636800_B28","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s007010050123","article-title":"Management of recurrent craniopharyngioma","volume":"140","author":"Caldarelli","year":"1998","journal-title":"Acta Neurochir (Wien)"},{"key":"key\n\t\t\t\t2019041113263636800_B29","first-page":"2734","article-title":"Obesity in childhood craniopharyngioma: relation to post-operative hypothalamic damage shown by magnetic resonance imaging","volume":"81","author":"de Vile","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B30","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1055\/s-2001-16855","article-title":"Obesity after childhood craniopharyngioma\u2014German multicenter study on pre-operative risk factors and quality of life","volume":"213","author":"Muller","year":"2001","journal-title":"Klin Padiatr"},{"key":"key\n\t\t\t\t2019041113263636800_B31","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s00381-005-1205-6","article-title":"Social and psycho-intellectual outcome following radical removal of craniopharyngiomas in childhood. A prospective series","volume":"21","author":"Pierre-Kahn","year":"2005","journal-title":"Childs Nerv Syst"},{"key":"key\n\t\t\t\t2019041113263636800_B32","first-page":"421","article-title":"Influence of tumor location on the presentation and evolution of craniopharyngiomas","volume":"103","author":"Meuric","year":"2005","journal-title":"J Neurosurg"},{"key":"key\n\t\t\t\t2019041113263636800_B33","first-page":"482","article-title":"Long-term results of gamma knife surgery for the treatment of craniopharyngioma in 98 consecutive cases","volume":"103","author":"Kobayashi","year":"2005","journal-title":"J Neurosurg"},{"key":"key\n\t\t\t\t2019041113263636800_B34","first-page":"987","article-title":"[Craniopharyngiomas: role of radiotherapy]","volume":"94","author":"Chargari","year":"2007","journal-title":"Bull Cancer"},{"key":"key\n\t\t\t\t2019041113263636800_B35","first-page":"439","article-title":"Craniopharyngioma radiotherapy: endocrine and cognitive effects","volume":"19","author":"Merchant","year":"2006","journal-title":"J Pediatr Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B36","first-page":"389","article-title":"Radiation therapy in the management of craniopharyngioma: current concepts and future developments","volume":"19","author":"Habrand","year":"2006","journal-title":"J Pediatr Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113263636800_B37","first-page":"155","article-title":"Fractionated proton radiation treatment for pediatric craniopharyngioma: preliminary report","volume":"12","author":"Luu","year":"2006","journal-title":"Cancer J"},{"key":"key\n\t\t\t\t2019041113263636800_B38","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1227\/00006123-198209000-00008","article-title":"Craniopharyngiomas in children","volume":"11","author":"Carmel","year":"1982","journal-title":"Neurosurgery"},{"key":"key\n\t\t\t\t2019041113263636800_B39","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3171\/jns.1990.73.1.0003","article-title":"Total removal of craniopharyngiomas. Approaches and long-term results in 144 patients","volume":"73","author":"Yasargil","year":"1990","journal-title":"J Neurosurg"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/98\/6\/2376\/10422728\/jcem2376.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T04:16:43Z","timestamp":1595737003000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/98\/6\/2376\/2537070"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,1]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2012-3928","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,1]]}}}