{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T19:24:30Z","timestamp":1769109870221,"version":"3.49.0"},"reference-count":20,"publisher":"The Endocrine Society","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,9,1]]},"DOI":"10.1210\/jc.2014-2288","type":"journal-article","created":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T15:49:24Z","timestamp":1405093764000},"page":"E1732-E1737","source":"Crossref","is-referenced-by-count":27,"title":["Effects of Escitalopram on Markers of Bone Turnover: A Randomized Clinical Trial"],"prefix":"10.1210","volume":"99","author":[{"given":"Susan J.","family":"Diem","sequence":"first","affiliation":[{"name":"University of Minnesota (S.J.D., K.E.E.), Minneapolis, Minnesota 55415"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadine","family":"Joffe","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital and Dana Farber Cancer Institute (H.J.), Boston, Massachusetts 02115"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph C.","family":"Larson","sequence":"additional","affiliation":[{"name":"Fred Hutchinson Cancer Research Center (J.C.L., A.Z.L.), Seattle, Washington 98109"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joy N.","family":"Tsai","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital (J.N.T., B.Z.L.), Boston, Massachusetts 02114"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine A.","family":"Guthrie","sequence":"additional","affiliation":[{"name":"University of Minnesota (S.J.D., K.E.E.), Minneapolis, Minnesota 55415"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Z.","family":"LaCroix","sequence":"additional","affiliation":[{"name":"Fred Hutchinson Cancer Research Center (J.C.L., A.Z.L.), Seattle, Washington 98109"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristine E.","family":"Ensrud","sequence":"additional","affiliation":[{"name":"University of Minnesota (S.J.D., K.E.E.), Minneapolis, Minnesota 55415"},{"name":"Minneapolis Veterans Affairs Health Care System (K.E.E.), Minneapolis, Minnesota 55417"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen W.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine (E.W.F.), University of Pennsylvania, Philadelphia, Pennsylvania 19104"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin Z.","family":"Leder","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital (J.N.T., B.Z.L.), Boston, Massachusetts 02114"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041114160962500_B1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.bone.2009.07.083","article-title":"Effects of selective serotonin reuptake inhibitors on bone health in adults: time for recommendations about screening, prevention and management?","volume":"46","author":"Haney","year":"2010","journal-title":"Bone"},{"key":"key\n\t\t\t\t2019041114160962500_B2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.bone.2009.06.029","article-title":"The emerging role of serotonin (5-hydroxytryptamine) in the skeleton and its mediation of the skeletal effects of low-density lipoprotein receptor-related protein 5 (LRP5)","volume":"46","author":"Warden","year":"2010","journal-title":"Bone"},{"key":"key\n\t\t\t\t2019041114160962500_B3","doi-asserted-by":"crossref","first-page":"4355","DOI":"10.1210\/jc.2013-1971","article-title":"Rates of bone loss among women initiating antidepressant medication use in midlife","volume":"98","author":"Diem","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114160962500_B4","first-page":"133","article-title":"Skeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: evidence from clinical studies","volume":"8","author":"Haney","year":"2008","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"key\n\t\t\t\t2019041114160962500_B5","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.euroneuro.2009.05.001","article-title":"SSRIs, bone mineral density, and risk of fractures\u2014a review","volume":"19","author":"Schwan","year":"2009","journal-title":"Eur Neuropsychopharmacol"},{"key":"key\n\t\t\t\t2019041114160962500_B6","unstructured":"National Osteoporosis Foundation. Clinician's guide to prevention and treatment of osteoporosis. http:nof.org\/hcp\/clincians-guide. (updated April 1, 2014)Assessed July 21, 2014. http:\/\/nof.org\/files\/nof\/public\/content\/file\/2791\/upload\/919.pdf. Assessed July 21, 2014."},{"key":"key\n\t\t\t\t2019041114160962500_B7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1001\/jama.2010.2016","article-title":"Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial","volume":"305","author":"Freeman","year":"2011","journal-title":"JAMA"},{"key":"key\n\t\t\t\t2019041114160962500_B8","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J Gen Intern Med"},{"key":"key\n\t\t\t\t2019041114160962500_B9","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t2019041114160962500_B10","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1001\/archinte.167.12.1246","article-title":"Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men","volume":"167","author":"Haney","year":"2007","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t2019041114160962500_B11","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1001\/archinte.167.12.1240","article-title":"Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures","volume":"167","author":"Diem","year":"2007","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t2019041114160962500_B12","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s00198-011-1778-8","article-title":"Selective serotonin reuptake inhibitor treatment and risk of fractures: a meta-analysis of cohort and case-control studies","volume":"23","author":"Wu","year":"2012","journal-title":"Osteoporos Int"},{"key":"key\n\t\t\t\t2019041114160962500_B13","first-page":"121","article-title":"Skeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: evidence from in vitro and animal-based studies","volume":"8","author":"Warden","year":"2008","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"key\n\t\t\t\t2019041114160962500_B14","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/j.1532-5415.2007.01194.x","article-title":"Depressive symptoms and rates of bone loss at the hip in older women","volume":"55","author":"Diem","year":"2007","journal-title":"J Am Geriatr Soc"},{"key":"key\n\t\t\t\t2019041114160962500_B15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00198-007-0449-2","article-title":"Depression and osteoporosis: epidemiology and potential mediating pathways","volume":"19","author":"Mezuk","year":"2008","journal-title":"Osteoporos Int"},{"key":"key\n\t\t\t\t2019041114160962500_B16","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.jpsychires.2011.04.005","article-title":"Treatment of a major depression episode suppresses markers of bone turnover in premenopausal women","volume":"45","author":"Aydin","year":"2011","journal-title":"J Psychiatr Res"},{"key":"key\n\t\t\t\t2019041114160962500_B17","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1007\/s00198-012-2170-z","article-title":"Serotonin-norepinephrine reuptake inhibitor therapy in late-life depression is associated with increased marker of bone resorption","volume":"24","author":"Shea","year":"2013","journal-title":"Osteoporos Int"},{"key":"key\n\t\t\t\t2019041114160962500_B18","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1056\/NEJMoa044459","article-title":"Denosumab in postmenopausal women with low bone mineral density","volume":"354","author":"McClung","year":"2006","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041114160962500_B19","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1210\/jc.2007-2814","article-title":"Effects of denosumab on bone mineral density and bone turnover in postmenopausal women","volume":"93","author":"Bone","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041114160962500_B20","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s11606-008-0525-0","article-title":"Depressive symptoms, bone loss, and fractures in postmenopausal women","volume":"23","author":"Spangler","year":"2008","journal-title":"J Gen Intern Med"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/99\/9\/E1732\/9046891\/jcem1732.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T18:51:06Z","timestamp":1565635866000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/99\/9\/E1732\/2537579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,1]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2014-2288","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,1]]}}}