{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:25:16Z","timestamp":1756463116729},"reference-count":5,"publisher":"The Endocrine Society","issue":"1","funder":[{"name":"Sichuan Provincial Innovation Team of Science and Technology","award":["2017TD0004"],"award-info":[{"award-number":["2017TD0004"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,1,1]]},"abstract":"Abstract<\/jats:title>\n \n Context<\/jats:title>\n Catecholamine-related factors are the most popular explanation for the occurrence of Takotsubo syndrome. An aldosterone-related mechanism, however, has not been proposed.<\/jats:p>\n <\/jats:sec>\n \n Case Description<\/jats:title>\n A 45-year-old male patient presenting with ST-segment elevation myocardial infarction was diagnosed with primary aldosteronism, severe hypokalemia, and Takotsubo syndrome. After excluding the known conditions of apical ballooning and the factors of vasospasm, primary aldosteronism is considered as the major contributor to the development of Takotsubo syndrome. The potential mechanisms are discussed.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The case suggests a possible hyperaldosteronism-induced and vasoconstriction-mediated mechanism in the development of Takotsubo syndrome.<\/jats:p>\n <\/jats:sec>","DOI":"10.1210\/jc.2017-01117","type":"journal-article","created":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T18:08:49Z","timestamp":1509473329000},"page":"12-15","source":"Crossref","is-referenced-by-count":6,"title":["An Unusual Case of Takotsubo Syndrome With Hyperaldosteronism as the Potential Cause"],"prefix":"10.1210","volume":"103","author":[{"given":"Yuanweixiang","family":"Ou","sequence":"first","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayyu","family":"Tsauo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Licheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2017,10,31]]},"reference":[{"issue":"7","key":"2020071621220863100_B1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/nrcardio.2015.39","article-title":"Epidemiology and pathophysiology of Takotsubo syndrome","volume":"12","author":"Akashi","year":"2015","journal-title":"Nat Rev Cardiol"},{"issue":"11","key":"2020071621220863100_B2","doi-asserted-by":"crossref","first-page":"4339","DOI":"10.1210\/jc.2015-2752","article-title":"Aldosterone impairs vascular smooth muscle function: from clinical to bench research","volume":"100","author":"Chou","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2020071621220863100_B3","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/ki.2009.490","article-title":"Endothelial cells as vascular salt sensors","volume":"77","author":"Oberleithner","year":"2010","journal-title":"Kidney Int"},{"issue":"3","key":"2020071621220863100_B4","doi-asserted-by":"crossref","first-page":"H978","DOI":"10.1152\/ajpheart.00538.2005","article-title":"Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension","volume":"290","author":"Rodriguez-Porcel","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"3","key":"2020071621220863100_B5","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.ijcard.2014.04.221","article-title":"Systematic review and meta-analysis of incidence and correlates of recurrence of takotsubo cardiomyopathy","volume":"174","author":"Singh","year":"2014","journal-title":"Int J Cardiol"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/103\/1\/12\/23273117\/jc.2017-01117.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/103\/1\/12\/23273117\/jc.2017-01117.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T07:31:34Z","timestamp":1594971094000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/103\/1\/12\/4583440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,31]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2017-01117","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,1]]},"published":{"date-parts":[[2017,10,31]]}}}