{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:23:11Z","timestamp":1792174991228,"version":"4.4.0"},"reference-count":25,"publisher":"The Endocrine Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,1]]},"DOI":"10.1210\/jc.2018-01532","type":"journal-article","created":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T14:01:01Z","timestamp":1540994461000},"page":"312-318","source":"Crossref","is-referenced-by-count":120,"title":["CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma"],"prefix":"10.1210","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4995-8108","authenticated-orcid":false,"given":"Letizia","family":"Canu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands"},{"name":"Department of Experimental and Clinical Biomedical Sciences University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janna A W","family":"Van Hemert","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiel N","family":"Kerstens","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P","family":"Hartman","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakanksha","family":"Khanna","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Kraljevic","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University Hospital Center Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darko","family":"Kastelan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University Hospital Center Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corin","family":"Badiu","sequence":"additional","affiliation":[{"name":"National Institute of Endocrinology C. I. Parhon, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urszula","family":"Ambroziak","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Tabarin","sequence":"additional","affiliation":[{"name":"Service d'Endocrinologie H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magalie","family":"Haissaguerre","sequence":"additional","affiliation":[{"name":"Service d'Endocrinologie H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Buitenwerf","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anneke","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Applied Health Research, University of Groningen, University Medical Center Groningen, GZ Groningen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Mannelli","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Biomedical Sciences University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebke","family":"Arlt","sequence":"additional","affiliation":[{"name":"Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios","family":"Chortis","sequence":"additional","affiliation":[{"name":"Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Bourdeau","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Center Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Gagnon","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Center Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Buchy","sequence":"additional","affiliation":[{"name":"F\u00e9d\u00e9ration d'Endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francoise","family":"Borson-Chazot","sequence":"additional","affiliation":[{"name":"F\u00e9d\u00e9ration d'Endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Deutschbein","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Fassnacht","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany"},{"name":"Comprehensive Cancer Center Mainfranken, University of Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Hubalewska-Dydejczyk","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Motyka","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewelina","family":"Rzepka","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth T","family":"Casey","sequence":"additional","affiliation":[{"name":"Addenbrooke's Hospital, Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge and NIHR Biomedical Research Center, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin G","family":"Challis","sequence":"additional","affiliation":[{"name":"Addenbrooke's Hospital, Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge and NIHR Biomedical Research Center, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Quinkler","sequence":"additional","affiliation":[{"name":"Endocrinology in Charlottenburg, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Vroonen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Center Hospitalier Universitaire de Li\u00e8ge, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadni","family":"Spyroglou","sequence":"additional","affiliation":[{"name":"Medizinische Klinik und Poliklinik IV Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Klinik f\u00fcr Endokrinologie, Diabetologie und Klinische Ern\u00e4hrung, Universit\u00e4tsSpital Z\u00fcrich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Beuschlein","sequence":"additional","affiliation":[{"name":"Medizinische Klinik und Poliklinik IV Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Klinik f\u00fcr Endokrinologie, Diabetologie und Klinische Ern\u00e4hrung, Universit\u00e4tsSpital Z\u00fcrich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Lamas","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Hospital General Universitario de Albacete, Albacete, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F","family":"Young","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Bancos","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri J L M","family":"Timmers","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2018,10,31]]},"reference":[{"issue":"6","key":"key\n\t\t\t\t2018121910131228000_B1","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1210\/jc.2014-1498","article-title":"Pheochromocytoma and paraganglioma: an Endocrine Society clinical practice guideline","volume":"99","author":"Lenders","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2018121910131228000_B2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ejim.2018.01.015","article-title":"Incidence of pheochromocytoma and sympathetic paraganglioma in the Netherlands: a nationwide study and systematic review","volume":"51","author":"Berends","year":"2018","journal-title":"Eur J Intern Med"},{"issue":"21","key":"key\n\t\t\t\t2018121910131228000_B3","doi-asserted-by":"crossref","first-page":"9651","DOI":"10.1158\/0008-5472.CAN-05-1427","article-title":"Novel pheochromocytoma susceptibility loci identified by integrative genomics","volume":"65","author":"Dahia","year":"2005","journal-title":"Cancer Res"},{"issue":"3","key":"key\n\t\t\t\t2018121910131228000_B4","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/MED.0b013e32835fcc45","article-title":"Genetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment options","volume":"20","author":"Vicha","year":"2013","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"issue":"2","key":"key\n\t\t\t\t2018121910131228000_B5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nrendo.2014.188","article-title":"Paraganglioma and phaeochromocytoma: from genetics to personalized medicine","volume":"11","author":"Favier","year":"2015","journal-title":"Nat Rev Endocrinol"},{"issue":"9486","key":"key\n\t\t\t\t2018121910131228000_B6","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0140-6736(05)67139-5","article-title":"Phaeochromocytoma","volume":"366","author":"Lenders","year":"2005","journal-title":"Lancet"},{"issue":"2","key":"key\n\t\t\t\t2018121910131228000_B7","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1530\/EJE-16-0467","article-title":"Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors","volume":"175","author":"Fassnacht","year":"2016","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"key\n\t\t\t\t2018121910131228000_B8","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1530\/EJE-09-0384","article-title":"Frequent incidental discovery of phaeochromocytoma: data from a German cohort of 201 phaeochromocytoma","volume":"161","author":"Kopetschke","year":"2009","journal-title":"Eur J Endocrinol"},{"issue":"1","key":"key\n\t\t\t\t2018121910131228000_B9","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1080\/08998280.2003.11927882","article-title":"Evaluation and management of the incidental adrenal mass","volume":"16","author":"Arnold","year":"2003","journal-title":"Proc Bayl Univ Med Cent"},{"issue":"7","key":"key\n\t\t\t\t2018121910131228000_B10","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1210\/jc.2011-0085","article-title":"Medical and surgical evaluation and treatment of adrenal incidentalomas","volume":"96","author":"Zeiger","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"key\n\t\t\t\t2018121910131228000_B11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.beem.2009.04.001","article-title":"Management of adrenal incidentaloma","volume":"23","author":"Terzolo","year":"2009","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"6","key":"key\n\t\t\t\t2018121910131228000_B12","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1056\/NEJMcp065470","article-title":"Clinical practice. The incidentally discovered adrenal mass","volume":"356","author":"Young","year":"2007","journal-title":"N Engl J Med"},{"issue":"3","key":"key\n\t\t\t\t2018121910131228000_B13","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1046\/j.1365-2796.2002.01028.x","article-title":"Adrenal incidentaloma\u2014experience of a standardized diagnostic programme in the Swedish prospective study","volume":"252","author":"B\u00fclow","year":"2002","journal-title":"J Intern Med"},{"issue":"4","key":"key\n\t\t\t\t2018121910131228000_B14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1530\/eje.0.1490273","article-title":"Prevalence and natural history of adrenal incidentalomas","volume":"149","author":"Barzon","year":"2003","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"key\n\t\t\t\t2018121910131228000_B15","doi-asserted-by":"crossref","first-page":"R51","DOI":"10.1530\/EJE-16-0461","article-title":"anagement of endocrine disease: imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis","volume":"175","author":"Dinnes","year":"2016","journal-title":"Eur J Endocrinol"},{"issue":"6","key":"key\n\t\t\t\t2018121910131228000_B16","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1210\/jc.2012-1061","article-title":"Is biochemical screening for pheochromocytoma in adrenal incidentalomas expressing low unenhanced attenuation on computed tomography necessary","volume":"97","author":"Sane","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"key\n\t\t\t\t2018121910131228000_B17","doi-asserted-by":"crossref","first-page":"481","DOI":"10.3803\/EnM.2015.30.4.481","article-title":"A 5-year prospective follow-up study of lipid-rich adrenal incidentalomas: no tumor growth or development of hormonal hypersecretion","volume":"30","author":"Schalin-J\u00e4ntti","year":"2015","journal-title":"Endocrinol Metab (Seoul)"},{"issue":"6","key":"key\n\t\t\t\t2018121910131228000_B18","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.2214\/ajr.181.6.1811663","article-title":"Low-density pheochromocytoma on CT: a mimicker of adrenal adenoma","volume":"181","author":"Blake","year":"2003","journal-title":"AJR Am J Roentgenol"},{"issue":"45","key":"key\n\t\t\t\t2018121910131228000_B19","doi-asserted-by":"crossref","first-page":"e1948","DOI":"10.1097\/MD.0000000000001948","article-title":"Is preoperative biochemical testing for pheochromocytoma necessary for all adrenal incidentalomas","volume":"94","author":"Jun","year":"2015","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"key\n\t\t\t\t2018121910131228000_B20","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1530\/EJE-18-0006","article-title":"Unenhanced CT imaging is highly sensitive to exclude pheochromocytoma: a multicenter study","volume":"178","author":"Buitenwerf","year":"2018","journal-title":"Eur J Endocrinol"},{"issue":"1","key":"key\n\t\t\t\t2018121910131228000_B21","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1677\/ERC-10-0211","article-title":"Catecholamine metabolomic and secretory phenotypes in phaeochromocytoma","volume":"18","author":"Eisenhofer","year":"2010","journal-title":"Endocr Relat Cancer"},{"key":"key\n\t\t\t\t2018121910131228000_B22","unstructured":"Canu L, Van Hemert JAW., Kerstens M, Hartman RP, Khanna A., Kraljevic I, Kastelan D, Badiu C, Ambroziak U, Tabarin A, Haissaguerre M, Buitenwerf E, Visser A, Mannelli M, Arlt W, Chortis V, Bourdeau I, Gagnon N, Buchy M, Borson-Chazot F, Deutschbein T, Fassnacht M, Hubalewska Dydejczy H. A, Motyka M, Rzepka E, Casey R T, Challis B G, Quinkler M, Vroonen L, Spyroglou A, Beuschlein F, Lamas C, Young W F, Bancos I, Timmers H J L M. Canu_SupdataTab1.pdf."},{"issue":"12","key":"key\n\t\t\t\t2018121910131228000_B23","doi-asserted-by":"crossref","first-page":"3147","DOI":"10.1007\/s00268-017-4110-8","article-title":"Pheochromocytoma with Synchronous Ipsilateral Adrenal Cortical Adenoma","volume":"41","author":"Hasassri","year":"2017","journal-title":"World J Surg"},{"issue":"3","key":"key\n\t\t\t\t2018121910131228000_B24","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1007\/s00330-017-5076-5","article-title":"Pheochromocytoma as a frequent false-positive in adrenal washout CT: A systematic review and meta-analysis","volume":"28","author":"Woo","year":"2018","journal-title":"Eur Radiol"},{"issue":"6","key":"key\n\t\t\t\t2018121910131228000_B25","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.1120\/jacmp.v14i6.4417","article-title":"Scanner and kVp dependence of measured CT numbers in the ACR CT phantom","volume":"14","author":"Cropp","year":"2013","journal-title":"J Appl Clin Med Phys"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/104\/2\/312\/27193116\/jc.2018-01532.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T02:59:42Z","timestamp":1572404382000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/104\/2\/312\/5148137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,31]]},"references-count":25,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,10,31]]},"published-print":{"date-parts":[[2019,2,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2018-01532","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,2]]},"published":{"date-parts":[[2018,10,31]]}}}