{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:37:14Z","timestamp":1787740634578,"version":"build-2784847793"},"reference-count":62,"publisher":"The Endocrine Society","issue":"4","funder":[{"DOI":"10.13039\/100008052","name":"Fundaci\u00f3n Alfonso Mart\u00edn Escudero","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH103402"],"award-info":[{"award-number":["R01 MH103402"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH103402"],"award-info":[{"award-number":["R01 MH103402"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH103402"],"award-info":[{"award-number":["R01 MH103402"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH083657"],"award-info":[{"award-number":["R01 MH083657"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23 MH092560"],"award-info":[{"award-number":["K23 MH092560"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 DK040561"],"award-info":[{"award-number":["P30 DK040561"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1 UL1 TR001102-01"],"award-info":[{"award-number":["1 UL1 TR001102-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["8 ULI TR000170-05"],"award-info":[{"award-number":["8 ULI TR000170-05"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Oxytocin regulates a range of physiological processes including eating behavior and oxytocin administration reduces caloric intake in males. There are few data on oxytocin and eating behavior in healthy females or on the response of endogenous oxytocin to food intake and its relationship to appetite in humans.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To determine the postprandial pattern of oxytocin levels, the relationship between oxytocin and appetite, and the impact of menstrual cycle phase and age on oxytocin levels in females.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Cross-sectional.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Clinical research center.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>Fifty-five healthy females (age 10 to 45 years).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Interventions<\/jats:title>\n                  <jats:p>A standardized mixed meal was administered.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main Outcome Measurements<\/jats:title>\n                  <jats:p>Blood sampling for oxytocin occurred at fasting and at 30, 60, and 120 minutes postmeal. Appetite was assessed using Visual Analogue Scales pre- and postmeal.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Mean fasting oxytocin levels were 1011.2 \u00b1 52.3 pg\/mL (SEM) and decreased at 30 and 60 minutes postmeal (P = 0.001 and P = 0.003, respectively). Mean oxytocin levels decreased19.6% \u00b1 3.0% from baseline to nadir. Oxytocin area under the curve was lower in the early to midfollicular menstrual cycle phase (P = 0.0003) and higher in younger females (P = 0.002). The percent change in oxytocin (baseline to nadir) was associated with postprandial hunger (rs = -0.291, P = 0.03) and fullness (rs = 0.345, P = 0.009). These relations remained significant after controlling for calories consumed, menstrual cycle status, and age (P = 0.023 and P = 0.0001, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Peripheral oxytocin levels in females decrease after a mixed meal and are associated with appetite independent of menstrual phase, age, and caloric intake, suggesting that endogenous oxytocin levels may play a role in perceived hunger and satiety.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jc.2018-02036","type":"journal-article","created":{"date-parts":[[2019,3,9]],"date-time":"2019-03-09T14:46:07Z","timestamp":1552142767000},"page":"1348-1356","source":"Crossref","is-referenced-by-count":31,"title":["Endogenous Oxytocin Levels in Relation to Food Intake, Menstrual Phase, and Age in Females"],"prefix":"10.1210","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1205-7114","authenticated-orcid":false,"given":"Anna","family":"Aulinas","sequence":"first","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reitumetse L","family":"Pulumo","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Asanza","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J","family":"Mancuso","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Slattery","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Tolley","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Plessow","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J","family":"Thomas","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston Massachusetts"},{"name":"Eating Disorders Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamryn T","family":"Eddy","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston Massachusetts"},{"name":"Eating Disorders Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen K","family":"Miller","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Klibanski","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhusmita","family":"Misra","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston Massachusetts"},{"name":"Pediatric Endocrine Unit, Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A","family":"Lawson","sequence":"additional","affiliation":[{"name":"Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2018,11,16]]},"reference":[{"issue":"12","key":"2020071622420605800_B1","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nrendo.2017.115","article-title":"The effects of oxytocin on eating behaviour and metabolism in humans","volume":"13","author":"Lawson","year":"2017","journal-title":"Nat Rev Endocrinol"},{"issue":"9","key":"2020071622420605800_B2","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1097\/WNR.0b013e3283021ca9","article-title":"Oxytocin receptor-deficient mice developed late-onset obesity","volume":"19","author":"Takayanagi","year":"2008","journal-title":"Neuroreport"},{"issue":"1","key":"2020071622420605800_B3","doi-asserted-by":"crossref","first-page":"E134","DOI":"10.1152\/ajpendo.00296.2011","article-title":"Peripheral oxytocin suppresses food intake and causes weight loss in diet-induced obese rats","volume":"302","author":"Morton","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"12","key":"2020071622420605800_B4","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.18632\/aging.100408","article-title":"Peripheral oxytocin treatment ameliorates obesity by reducing food intake and visceral fat mass","volume":"3","author":"Maejima","year":"2011","journal-title":"Aging (Albany NY)"},{"issue":"4","key":"2020071622420605800_B5","doi-asserted-by":"crossref","first-page":"R357","DOI":"10.1152\/ajpregu.00169.2017","article-title":"Chronic hindbrain administration of oxytocin is sufficient to elicit weight loss in diet-induced obese rats","volume":"313","author":"Roberts","year":"2017","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"3","key":"2020071622420605800_B6","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.neuron.2010.12.036","article-title":"Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance","volume":"69","author":"Zhang","year":"2011","journal-title":"Neuron"},{"issue":"9","key":"2020071622420605800_B7","doi-asserted-by":"crossref","first-page":"R800","DOI":"10.1152\/ajpregu.00534.2014","article-title":"Medial nucleus tractus solitarius oxytocin receptor signaling and food intake control: the role of gastrointestinal satiation signal processing","volume":"308","author":"Ong","year":"2015","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"1","key":"2020071622420605800_B8","doi-asserted-by":"crossref","first-page":"R99","DOI":"10.1152\/ajpregu.00008.2002","article-title":"GLP-1 receptor signaling contributes to anorexigenic effect of centrally administered oxytocin in rats","volume":"283","author":"Rinaman","year":"2002","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"6","key":"2020071622420605800_B9","doi-asserted-by":"crossref","first-page":"R737","DOI":"10.1152\/ajpregu.00118.2014","article-title":"Oxytocin in the ventromedial hypothalamic nucleus reduces feeding and acutely increases energy expenditure","volume":"307","author":"Noble","year":"2014","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"6","key":"2020071622420605800_B10","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1097\/WNR.0000000000001005","article-title":"Oxytocin administration in the basolateral and central nuclei of amygdala moderately suppresses food intake","volume":"29","author":"Klockars","year":"2018","journal-title":"Neuroreport"},{"issue":"8","key":"2020071622420605800_B11","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1210\/en.2014-1148","article-title":"Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats","volume":"155","author":"Ho","year":"2014","journal-title":"Endocrinology"},{"issue":"4","key":"2020071622420605800_B12","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12381","article-title":"Oxytocin acting in the nucleus accumbens core decreases food intake","volume":"28","author":"Herisson","year":"2016","journal-title":"J Neuroendocrinol"},{"key":"2020071622420605800_B13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.brainres.2013.03.026","article-title":"Oxytocin action in the ventral tegmental area affects sucrose intake","volume":"1513","author":"Mullis","year":"2013","journal-title":"Brain Res"},{"issue":"2","key":"2020071622420605800_B14","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0031-9384(97)00021-8","article-title":"Effects of central oxytocin administration on intraoral intake of glucose in deprived and nondeprived rats","volume":"62","author":"Lokrantz","year":"1997","journal-title":"Physiol Behav"},{"issue":"5","key":"2020071622420605800_B15","doi-asserted-by":"crossref","first-page":"R431","DOI":"10.1152\/ajpregu.00441.2014","article-title":"Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys","volume":"308","author":"Blevins","year":"2015","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"5","key":"2020071622420605800_B16","doi-asserted-by":"crossref","first-page":"e61477","DOI":"10.1371\/journal.pone.0061477","article-title":"Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"issue":"9","key":"2020071622420605800_B17","doi-asserted-by":"crossref","first-page":"e25565","DOI":"10.1371\/journal.pone.0025565","article-title":"Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats","volume":"6","author":"Deblon","year":"2011","journal-title":"PLoS One"},{"issue":"11","key":"2020071622420605800_B18","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.1210\/en.2014-1466","article-title":"Divergent effects of oxytocin treatment of obese diabetic mice on adiposity and diabetes","volume":"155","author":"Altirriba","year":"2014","journal-title":"Endocrinology"},{"issue":"4","key":"2020071622420605800_B19","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1210\/en.2014-1718","article-title":"Oxytocin treatment prevents the cardiomyopathy observed in obese diabetic male db\/db mice","volume":"156","author":"Plante","year":"2015","journal-title":"Endocrinology"},{"issue":"5","key":"2020071622420605800_B20","doi-asserted-by":"crossref","first-page":"R360","DOI":"10.1152\/ajpregu.00344.2014","article-title":"Peripheral oxytocin activates vagal afferent neurons to suppress feeding in normal and leptin-resistant mice: a route for ameliorating hyperphagia and obesity","volume":"308","author":"Iwasaki","year":"2015","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"1","key":"2020071622420605800_B21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1159\/000371636","article-title":"Nasal oxytocin administration reduces food intake without affecting locomotor activity and glycemia with c-Fos induction in limited brain areas","volume":"101","author":"Maejima","year":"2015","journal-title":"Neuroendocrinology"},{"issue":"23","key":"2020071622420605800_B22","doi-asserted-by":"crossref","first-page":"4404","DOI":"10.1016\/j.febslet.2014.10.010","article-title":"Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus","volume":"588","author":"Maejima","year":"2014","journal-title":"FEBS Lett"},{"issue":"5","key":"2020071622420605800_B23","doi-asserted-by":"crossref","first-page":"E1004","DOI":"10.1152\/ajpendo.00196.2011","article-title":"Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatment","volume":"301","author":"Zhang","year":"2011","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"7","key":"2020071622420605800_B24","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1210\/me.2008-0067","article-title":"Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice","volume":"22","author":"Kublaoui","year":"2008","journal-title":"Mol Endocrinol"},{"issue":"7","key":"2020071622420605800_B25","doi-asserted-by":"crossref","first-page":"R640","DOI":"10.1152\/ajpregu.00220.2015","article-title":"Chronic CNS oxytocin signaling preferentially induces fat loss in high-fat diet-fed rats by enhancing satiety responses and increasing lipid utilization","volume":"310","author":"Blevins","year":"2016","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"1","key":"2020071622420605800_B26","doi-asserted-by":"crossref","first-page":"8599","DOI":"10.1038\/s41598-017-09318-7","article-title":"Impact of sex, fat distribution and initial body weight on oxytocin\u2019s body weight regulation","volume":"7","author":"Maejima","year":"2017","journal-title":"Sci Rep"},{"issue":"4756","key":"2020071622420605800_B27","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1126\/science.3715453","article-title":"Oxytocin secretion in response to cholecystokinin and food: differentiation of nausea from satiety","volume":"232","author":"Verbalis","year":"1986","journal-title":"Science"},{"issue":"5","key":"2020071622420605800_B28","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1002\/oby.21069","article-title":"Oxytocin reduces caloric intake in men","volume":"23","author":"Lawson","year":"2015","journal-title":"Obesity (Silver Spring)"},{"issue":"11","key":"2020071622420605800_B29","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1038\/ijo.2016.149","article-title":"Oxytocin\u2019s inhibitory effect on food intake is stronger in obese than normal-weight men","volume":"40","author":"Thienel","year":"2016","journal-title":"Int J Obes"},{"key":"2020071622420605800_B30","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.appet.2018.08.003","article-title":"Rapid-onset anorectic effects of intranasal oxytocin in young men","volume":"130","author":"Burmester","year":"2018","journal-title":"Appetite"},{"issue":"2","key":"2020071622420605800_B31","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1210\/jc.2017-02080","article-title":"Oxytocin and Naltrexone Successfully Treat Hypothalamic Obesity in a Boy Post-Craniopharyngioma Resection","volume":"103","author":"Hsu","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2020071622420605800_B32","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-2982.2010.01599.x","article-title":"Oxytocin reduces satiety scores without affecting the volume of nutrient intake or gastric emptying rate in healthy subjects","volume":"23","author":"Borg","year":"2011","journal-title":"Neurogastroenterol Motil"},{"issue":"10","key":"2020071622420605800_B33","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.2337\/db13-0663","article-title":"Oxytocin reduces reward-driven food intake in humans","volume":"62","author":"Ott","year":"2013","journal-title":"Diabetes"},{"issue":"4","key":"2020071622420605800_B34","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1210\/jcem-68-4-837","article-title":"Neurohypophyseal secretion in response to cholecystokinin but not meal-induced gastric distention in humans","volume":"68","author":"Miaskiewicz","year":"1989","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"2020071622420605800_B35","first-page":"213","article-title":"Elevated plasma levels of oxytocin in obese subjects before and after gastric banding","volume":"13","author":"Stock","year":"1989","journal-title":"Int J Obes"},{"issue":"2","key":"2020071622420605800_B36","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1080\/11024150252884340","article-title":"Cholecystokinin stimulation leads to increased oxytocin secretion in women","volume":"168","author":"Ohlsson","year":"2002","journal-title":"Eur J Surg"},{"issue":"1","key":"2020071622420605800_B37","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.psychres.2014.04.031","article-title":"Gender differences in oxytocin-associated disruption of decision bias during emotion perception","volume":"219","author":"Lynn","year":"2014","journal-title":"Psychiatry Res"},{"key":"2020071622420605800_B38","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.psyneuen.2013.09.022","article-title":"Sex differences in the neural and behavioral response to intranasal oxytocin and vasopressin during human social interaction","volume":"39","author":"Rilling","year":"2014","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"2020071622420605800_B39","doi-asserted-by":"crossref","first-page":"4082","DOI":"10.1038\/ncomms5082","article-title":"Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration","volume":"5","author":"Elabd","year":"2014","journal-title":"Nat Commun"},{"key":"2020071622420605800_B40","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3389\/fnhum.2013.00487","article-title":"Oxytocin and socioemotional aging: Current knowledge and future trends","volume":"7","author":"Ebner","year":"2013","journal-title":"Front Hum Neurosci"},{"issue":"1471","key":"2020071622420605800_B41","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1098\/rstb.2006.1860","article-title":"Modulation of appetite by gonadal steroid hormones","volume":"361","author":"Asarian","year":"2006","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"6","key":"2020071622420605800_B42","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/0031-9384(95)02003-9","article-title":"Food intake and the menstrual cycle: a retrospective analysis, with implications for appetite research","volume":"58","author":"Buffenstein","year":"1995","journal-title":"Physiol Behav"},{"issue":"10","key":"2020071622420605800_B43","doi-asserted-by":"crossref","first-page":"E1898","DOI":"10.1210\/jc.2012-1702","article-title":"Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa","volume":"97","author":"Lawson","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"2020071622420605800_B44","doi-asserted-by":"crossref","first-page":"e451","DOI":"10.4088\/JCP.12m08154","article-title":"Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa","volume":"74","author":"Lawson","year":"2013","journal-title":"J Clin Psychiatry"},{"issue":"10","key":"2020071622420605800_B45","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.2337\/dc15-2721","article-title":"Differences in regional brain responses to food ingestion after Roux-en-Y gastric bypass and the role of gut peptides: a neuroimaging study","volume":"39","author":"Hunt","year":"2016","journal-title":"Diabetes Care"},{"issue":"1","key":"2020071622420605800_B46","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/sj.ijo.0801083","article-title":"Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies","volume":"24","author":"Flint","year":"2000","journal-title":"Int J Obes Relat Metab Disord"},{"issue":"3","key":"2020071622420605800_B47","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1530\/EJE-12-0869","article-title":"Nocturnal oxytocin secretion is lower in amenorrheic athletes than nonathletes and associated with bone microarchitecture and finite element analysis parameters","volume":"168","author":"Lawson","year":"2013","journal-title":"Eur J Endocrinol"},{"issue":"7","key":"2020071622420605800_B48","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/S0306-4530(02)00108-7","article-title":"Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change","volume":"28","author":"Pruessner","year":"2003","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"2020071622420605800_B49","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1748-1716.1985.tb07674.x","article-title":"Plasma levels of oxytocin increase in response to suckling and feeding in dogs and sows","volume":"124","author":"Uvn\u00e4s-Moberg","year":"1985","journal-title":"Acta Physiol Scand"},{"issue":"4 Pt 2","key":"2020071622420605800_B50","first-page":"R661","article-title":"Cholecystokinin and gastric distension activate oxytocinergic cells in rat hypothalamus","volume":"253","author":"Renaud","year":"1987","journal-title":"Am J Physiol"},{"issue":"32","key":"2020071622420605800_B51","doi-asserted-by":"crossref","first-page":"10351","DOI":"10.1523\/JNEUROSCI.23-32-10351.2003","article-title":"Alpha-melanocyte-stimulating hormone stimulates oxytocin release from the dendrites of hypothalamic neurons while inhibiting oxytocin release from their terminals in the neurohypophysis","volume":"23","author":"Sabatier","year":"2003","journal-title":"J Neurosci"},{"issue":"6","key":"2020071622420605800_B52","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1210\/jcem-71-6-1531","article-title":"Pattern of oxytocin concentrations in the plasma and cerebrospinal fluid of lactating rhesus monkeys (Macaca mulatta): evidence for functionally independent oxytocinergic pathways in primates","volume":"71","author":"Amico","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"2020071622420605800_B53","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1046\/j.1365-2826.1998.00279.x","article-title":"Dendritic release of vasopressin and oxytocin","volume":"10","author":"Ludwig","year":"1998","journal-title":"J Neuroendocrinol"},{"issue":"2","key":"2020071622420605800_B54","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1210\/jcem-68-2-455","article-title":"Circulating immunoreactive oxytocin during the human menstrual cycle comes from the pituitary and is estradiol dependent","volume":"68","author":"Shukovski","year":"1989","journal-title":"J Clin Endocrinol Metab"},{"issue":"5 Pt 1","key":"2020071622420605800_B55","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/0002-9378(91)90399-C","article-title":"Oxytocin secretion and human parturition: pulse frequency and duration increase during spontaneous labor in women","volume":"165","author":"Fuchs","year":"1991","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"2020071622420605800_B56","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3109\/00016348909009906","article-title":"Plasma levels of gastrin, somatostatin, VIP, insulin and oxytocin during the menstrual cycle in women (with and without oral contraceptives)","volume":"68","author":"Uvn\u00e4s-Moberg","year":"1989","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"3","key":"2020071622420605800_B57","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1037\/a0019576","article-title":"Effects of age on cerebrospinal fluid oxytocin levels in free-ranging adult female and infant rhesus macaques","volume":"124","author":"Parker","year":"2010","journal-title":"Behav Neurosci"},{"issue":"4","key":"2020071622420605800_B58","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1046\/j.1460-9568.2000.00030.x","article-title":"Ageing alters intrahypothalamic release patterns of vasopressin and oxytocin in rats","volume":"12","author":"Keck","year":"2000","journal-title":"Eur J Neurosci"},{"issue":"1","key":"2020071622420605800_B59","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1159\/000341333","article-title":"Ageing and oxytocin: a call for extending human oxytocin research to ageing populations\u2014a mini-review","volume":"59","author":"Huffmeijer","year":"2013","journal-title":"Gerontology"},{"issue":"10","key":"2020071622420605800_B60","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1007\/BF01273321","article-title":"Hormonal influences on brain ageing quality: focus on corticotropin releasing hormone-, vasopressin- and oxytocin-immunoreactive neurones in the human brain","volume":"104","author":"Calz\u00e0","year":"1997","journal-title":"J Neural Transm (Vienna)"},{"issue":"5","key":"2020071622420605800_B61","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0197-4580(91)90081-T","article-title":"Oxytocin cell number in the human paraventricular nucleus remains constant with aging and in Alzheimer\u2019s disease","volume":"12","author":"Wierda","year":"1991","journal-title":"Neurobiol Aging"},{"issue":"4","key":"2020071622420605800_B62","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nrendo.2013.29","article-title":"Oxidative stress and the ageing endocrine system","volume":"9","author":"Vitale","year":"2013","journal-title":"Nat Rev Endocrinol"}],"container-title":["The Journal of Clinical Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/104\/4\/1348\/28030587\/jc.2018-02036.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/104\/4\/1348\/28030587\/jc.2018-02036.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T11:11:08Z","timestamp":1594984268000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/104\/4\/1348\/5184191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,16]]},"references-count":62,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2018-02036","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,4]]},"published":{"date-parts":[[2018,11,16]]}}}