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Groups were matched on age and body mass index. Primary outcome measures included intramyocardial triglyceride content (cardiac MRS) and diastolic function (cardiac MRI). Relationships between intramyocardial triglyceride content and clinical parameters were also assessed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among WHIV (vs non-HIV-infected women), intramyocardial triglyceride content was threefold higher [1.2 (0.4, 3.1) vs 0.4 (0.1, 0.5)%, P = 0.01], and diastolic function was reduced (left atrial passive ejection fraction: 27.2 \u00b1 9.6 vs 35.9 \u00b1 6.4%, P = 0.007). There was a strong inverse relationship between intramyocardial triglyceride content and diastolic function (\u03c1 = \u22120.62, P = 0.004). Among the whole group, intramyocardial triglyceride content did not relate to chronologic age but did increase across the reproductive aging spectrum (P = 0.02). HIV status and reproductive aging status remained independent predictors of intramyocardial triglyceride content after adjusting for relevant cardiometabolic parameters (overall model R2 = 0.56, P = 0.003; HIV status P = 0.01, reproductive aging status P = 0.02).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>For asymptomatic WHIV, increased intramyocardial triglyceride content is associated with diastolic dysfunction. Moreover, relationships between intramyocardial triglyceride accumulation and women\u2019s reproductive aging are noted.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jc.2019-01096","type":"journal-article","created":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T09:04:53Z","timestamp":1565255093000},"page":"6090-6100","source":"Crossref","is-referenced-by-count":27,"title":["Intramyocardial Triglycerides Among Women With vs Without HIV: Hormonal Correlates and Functional Consequences"],"prefix":"10.1210","volume":"104","author":[{"given":"Mabel","family":"Toribio","sequence":"first","affiliation":[{"name":"Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas G","family":"Neilan","sequence":"additional","affiliation":[{"name":"Cardiac MR PET, CT Program, Division of Cardiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical 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