{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:03:07Z","timestamp":1785855787253,"version":"3.56.0"},"reference-count":23,"publisher":"The Endocrine Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,8,1]]},"DOI":"10.1210\/jcem.85.8.6752","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T17:05:46Z","timestamp":1389200746000},"page":"2854-2859","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence of Primary Aldosteronism among Asian Hypertensive Patients in Singapore1"],"prefix":"10.1210","volume":"85","author":[{"given":"Keh-Chuan","family":"Loh","sequence":"first","affiliation":[{"name":"Endocrine Unit, Department of Medicine, Tan Tock Seng Hospital (K.-C.L.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn S.","family":"Koay","sequence":"additional","affiliation":[{"name":"Department of Pathology, National University of Singapore (E.S.K., M.-C.K.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Cheh","family":"Khaw","sequence":"additional","affiliation":[{"name":"Department of Pathology, National University of Singapore (E.S.K., M.-C.K.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanta C.","family":"Emmanuel","sequence":"additional","affiliation":[{"name":"Family Health Service, Ministry of Health (S.C.E.), Republic of Singapore, Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"William F.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mayo Clinic (W.F.Y.), Rochester, Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"2019041117341874700_R1","first-page":"6","article-title":"Primary aldosteronism, a new clinical syndrome.","volume":"45","year":"1955","journal-title":"J Lab Clin Med"},{"key":"2019041117341874700_R2","first-page":"213","article-title":"Suppression of plasma renin activity in primary aldosteronism.","volume":"190","author":"Conn","year":"1964","journal-title":"J Am Med Assoc"},{"key":"2019041117341874700_R3","first-page":"257","article-title":"The evolution of primary aldosteronism: 1954\u20131967.","volume":"62","year":"1968","journal-title":"Harvey Lect"},{"key":"2019041117341874700_R4","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1001\/archinte.1971.00310210056004","article-title":"Saline suppression of plasma aldosterone in hypertension.","volume":"128","author":"Kem","year":"1971","journal-title":"Arch Intern Med"},{"key":"2019041117341874700_R5","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1001\/jama.1977.03270400035014","article-title":"Diagnosis of secondary forms of hypertension.","volume":"237","author":"Grim","year":"1977","journal-title":"J Am Med Assoc"},{"key":"2019041117341874700_R6","doi-asserted-by":"crossref","first-page":"386","DOI":"10.7326\/0003-4819-90-3-386","article-title":"Primary aldosteronism: diagnosis, localization, and treatment.","volume":"90","author":"Weinberger","year":"1979","journal-title":"Ann Intern Med"},{"key":"2019041117341874700_R7","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0039-6060(96)80033-X","article-title":"Primary aldosteronism: adrenal venous sampling.","volume":"120","author":"Young","year":"1996","journal-title":"Surgery"},{"key":"2019041117341874700_R8","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1001\/archinte.1981.00340130033011","article-title":"A screening test to identify aldosterone-producing adenoma by measuring plasma renin activity.","volume":"141","author":"Hiramatsu","year":"1981","journal-title":"Arch Intern Med"},{"key":"2019041117341874700_R9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1440-1681.1985.tb02641.x","article-title":"Is aldosterone\/renin ratio useful to screen a hypertensive population for primary aldosteronism?","volume":"12","author":"Hamlet","year":"1985","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"2019041117341874700_R10","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1530\/acta.0.1130564","article-title":"Plasma aldosterone-plasma renin activity ratio: a simple test to identify patients with primary aldosteronism.","volume":"113","author":"Lins","year":"1986","journal-title":"Acta Endocrinol (Copenh)"},{"key":"2019041117341874700_R11","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1001\/archinte.1993.00410180075008","article-title":"The diagnosis of primary aldosteronism and separation of two major subtypes.","volume":"153","author":"Weinberger","year":"1993","journal-title":"Arch Intern Med"},{"key":"2019041117341874700_R12","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/sj.jhh.1000444","article-title":"Evaluation of plasma aldosterone to plasma renin activity ratio in patients with primary aldosteronism.","volume":"11","author":"Ignatowska-Switalska","year":"1997","journal-title":"J Hum Hypertens"},{"key":"2019041117341874700_R13","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1210\/jcem-57-5-892","article-title":"Single dose captopril as a diagnostic test for primary aldosteronism.","volume":"57","author":"Lyons","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"key":"2019041117341874700_R14","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1210\/jcem-73-5-952","article-title":"Diagnosis under random conditions of all disorders of the renin-angiotensin-aldosterone axis, including primary aldosteronism.","volume":"73","author":"McKenna","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"2019041117341874700_R15","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1440-1681.1994.tb02519.x","article-title":"High incidence of primary aldosteronism in 199 patients referred with hypertension.","volume":"21","author":"Gordon","year":"1994","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"2019041117341874700_R16","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/j.1445-5994.1996.tb00600.x","article-title":"Primary aldos-teronism: a missed diagnosis in \u201cessential hypertensives?\u201d","volume":"26","author":"Brown","year":"1996","journal-title":"Aust NZ J Med"},{"key":"2019041117341874700_R17","article-title":"Unexpectedly high prevalence of primary aldosteronism in a hypertensive population in Dundee","author":"Lim","year":"1998"},{"key":"2019041117341874700_R18","first-page":"731","article-title":"Screening of a population of young hypertensives for primary hyperaldosteronism (correspondence).","volume":"8","author":"Kumar","year":"1994","journal-title":"J Hum Hypertens"},{"key":"2019041117341874700_R19","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0140-6736(05)74868-6","article-title":"Potentially high prevalence of primary aldosteronism in a primary-care population.","volume":"353","author":"Lim","year":"1999","journal-title":"Lancet"},{"key":"2019041117341874700_R20","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0002-9343(83)91022-7","article-title":"The changing clinical spectrum of primary aldosteronism.","volume":"74","author":"Bravo","year":"1983","journal-title":"Am J Med"},{"key":"2019041117341874700_R21","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0022-4731(89)90164-7","article-title":"Identification and implications of new types of mineralocorticoid hypertension.","volume":"32","author":"Biglieri","year":"1989","journal-title":"J Steroid Biochem"},{"key":"2019041117341874700_R22","article-title":"Primary aldosteronism and other forms of mineralocorticoid hypertension. In: Swales JD, ed","author":"Gordon","year":"1994"},{"key":"2019041117341874700_R23","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1046\/j.1365-2265.1998.00608.x","article-title":"Screening for primary aldosteronism with a logistic multivariate discriminate analysis.","volume":"49","author":"Rossi","year":"1998","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/85\/8\/2854\/9180679\/jcem2854.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T05:54:33Z","timestamp":1555048473000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/85\/8\/2854\/2853470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8,1]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2000,8,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jcem.85.8.6752","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,8,1]]}}}