{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:52:34Z","timestamp":1753883554139,"version":"3.41.2"},"reference-count":8,"publisher":"The Endocrine Society","issue":"1","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":52,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We present a patient case referred for evaluation of male hypogonadism with gynecomastia. On examination, he was noted to have microtestis, shorter than expected height, and bilateral gynecomastia. Further investigation revealed XX genotype and on fluorescence in situ hybridization analysis confirmed the SRY gene was present on the short arm of 1 X chromosome. This case highlights the importance of detailed history and examination and the indication for genetic counseling in selected cases.<\/jats:p>","DOI":"10.1210\/jcemcr\/luac033","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T17:02:57Z","timestamp":1674234177000},"source":"Crossref","is-referenced-by-count":0,"title":["An Interesting Case of Hypogonadism: Workup in a Phenotypic Male Reveals XX Genotype"],"prefix":"10.1210","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8428-6303","authenticated-orcid":false,"given":"Tulsi","family":"Sharma","sequence":"first","affiliation":[{"name":"Cedar Falls High School, Division of Endocrinology and Metabolism, Mercy One , Waterloo, IA 50702 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshat","family":"Mehta","sequence":"additional","affiliation":[{"name":"Cedar Falls High School, Division of Endocrinology and Metabolism, Mercy One , Waterloo, IA 50702 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"issue":"1","key":"2023100215470354200_luac033-B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00283573","article-title":"Male pseudohermaphroditism: genetics and clinical delineation","volume":"44","author":"Simpson","year":"1978","journal-title":"Hum Genet"},{"issue":"3","key":"2023100215470354200_luac033-B2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.beem.2007.06.003","article-title":"Consequences of the ESPE\/LWPES guidelines for diagnosis and treatment of disorders of sex development","volume":"21","author":"Hughes","year":"2007","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"6","key":"2023100215470354200_luac033-B3","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1080\/15513815.2017.1379039","article-title":"Coexistence of trisomy 13 and SRY (-) XX ovotesticular disorder of sex development","volume":"36","author":"\u00dcrel Demir","year":"2017","journal-title":"Fetal Pediatr Pathol"},{"issue":"6","key":"2023100215470354200_luac033-B4","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1399-0004.2011.01832.x","article-title":"46, XY gonadal dysgenesis: new SRY point mutation in two siblings with paternal germline mosaicism","volume":"82","author":"Stoppa-Vaucher","year":"2012","journal-title":"Clin Genet"},{"volume-title":"GeneReviews\u00ae","year":"1993-2022","author":"D\u00e9lot","key":"2023100215470354200_luac033-B5"},{"issue":"5","key":"2023100215470354200_luac033-B6","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1210\/er.2006-0005","article-title":"Germ cell tumors in the intersex gonad: old paths, new directions, moving frontiers","volume":"27","author":"Cools","year":"2006","journal-title":"Endocr Rev"},{"issue":"2","key":"2023100215470354200_luac033-B7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0165-4608(87)90180-4","article-title":"Abnormal sexual differentiation and neoplasia","volume":"25","author":"Verp","year":"1987","journal-title":"Cancer Genet Cytogenet"},{"issue":"5","key":"2023100215470354200_luac033-B8","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1210\/jc.2018-00229","article-title":"Testosterone therapy in men with hypogonadism: an endocrine society clinical practice guideline","volume":"103","author":"Bhasin","year":"2018","journal-title":"J Clin Endocrinol Metab"}],"container-title":["JCEM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcemcr\/article-pdf\/1\/1\/luac033\/51824933\/luac033.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcemcr\/article-pdf\/1\/1\/luac033\/51824933\/luac033.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:47:23Z","timestamp":1696261643000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcemcr\/article\/doi\/10.1210\/jcemcr\/luac033\/6994176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,29]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,11,29]]}},"URL":"https:\/\/doi.org\/10.1210\/jcemcr\/luac033","relation":{},"ISSN":["2755-1520"],"issn-type":[{"type":"electronic","value":"2755-1520"}],"subject":[],"published-other":{"date-parts":[[2023,1,1]]},"published":{"date-parts":[[2022,11,29]]},"article-number":"luac033"}}