{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T20:12:07Z","timestamp":1780085527398,"version":"3.54.0"},"reference-count":10,"publisher":"The Endocrine Society","issue":"3","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":58,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hypoparathyroidism is a rare metabolic disease. In addition to symptoms of hypocalcemia, chronic hypoparathyroidism can result in brain calcifications leading to Fahr syndrome. Hypoparathyroidism most commonly results as a postsurgical complication, with autoimmune disease the second most common etiology. Here we report a 48-year-old man with symptoms of chronic hypocalcemia who presented with status epilepticus following severe coronavirus disease 2019 (COVID-19) infection. In addition to severe hypocalcemia, he was found to have an inappropriately low serum parathyroid hormone level and basal ganglia calcifications visualized on head computed tomography scan. He was treated with intravenous calcium infusion prior to transition to orally administered calcium, calcitriol, and high-dose cholecalciferol (vitamin D3).<\/jats:p>","DOI":"10.1210\/jcemcr\/luad072","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T10:34:45Z","timestamp":1687948485000},"source":"Crossref","is-referenced-by-count":3,"title":["Fahr Syndrome Presenting With Status Epilepticus After COVID-19 Infection"],"prefix":"10.1210","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9241-7628","authenticated-orcid":false,"given":"Helen Yifter","family":"Bitew","sequence":"first","affiliation":[{"name":"College of Medicine and Health Sciences, University of Rwanda , Kigali , Rwanda"},{"name":"Department of Internal Medicine, King Faisal Hospital , Kigali , Rwanda"},{"name":"College of Health Sciences, Addis Ababa University , Addis Ababa , Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Immaculate","family":"Kambutse","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences, University of Rwanda , Kigali , Rwanda"},{"name":"Department of Internal Medicine, King Faisal Hospital , Kigali , Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aloys","family":"Tuyizere","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences, University of Rwanda , Kigali , Rwanda"},{"name":"Department of Internal Medicine, King Faisal Hospital , Kigali , Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gakumba","family":"Claude","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences, University of Rwanda , Kigali , Rwanda"},{"name":"Department of Perioperative and Critical Care Services, King Faisal Hospital , Kigali , Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"issue":"1","key":"2023062810344204000_luad072-B1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/1750-1172-8-156","article-title":"Fahr's syndrome: literature review of current evidence","volume":"8","author":"Shafaq","year":"2013","journal-title":"Orphanet J Rare Dis"},{"issue":"3","key":"2023062810344204000_luad072-B2","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s12020-020-02383-5","article-title":"Hypocalcemia is highly prevalent and predicts hospitalization in patients with COVID-19","volume":"68","author":"Di Filippo","year":"2020","journal-title":"Endocrine"},{"issue":"9","key":"2023062810344204000_luad072-B3","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1016\/j.jiph.2020.05.029","article-title":"Prevalence and predictive value of hypocalcemia in severe COVID-19 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Endocrinol Metab"},{"issue":"6","key":"2023062810344204000_luad072-B7","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1210\/jc.2015-3909","article-title":"Presentation of hypoparathyroidism","volume":"101","author":"Shoback","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"2023062810344204000_luad072-B8","doi-asserted-by":"crossref","first-page":"e115832","DOI":"10.5812\/semj.115832","article-title":"Hypoparathyroidism after COVID-19 pneumonia","volume":"22","author":"Dianatfar","year":"2021","journal-title":"Shiraz E-Med J"},{"issue":"2","key":"2023062810344204000_luad072-B9","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s12020-020-02326-0","article-title":"Severe hypocalcemia in a thyroidectomized woman with COVID-19 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