{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T18:04:24Z","timestamp":1779905064527,"version":"3.53.1"},"reference-count":10,"publisher":"The Endocrine Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 54-year-old man with hypertension, type 2 diabetes mellitus, and a history of Merkel cell carcinoma (MCC) of the right thigh presented to the emergency department with a 4-day history of right lower-quadrant abdominal pain associated with constipation and decreased appetite. Workup showed a heterogenous 6-cm right adrenal mass with macroscopic fat. Imaging was suggestive of benign pathology. Hormonal workup for the adrenal nodule led to the diagnosis of Cushing syndrome. The patient underwent a right adrenalectomy for Cushing syndrome with pathology revealing a 6.5-cm adrenocortical adenoma harboring a 2-cm, well-circumscribed neuroendocrine tumor consistent with metastatic MCC. Adrenal collision tumors are exceedingly rare. This case describes a collision tumor that has not previously been identified\u2014a cortisol-producing adrenal adenoma and metastatic MCC.<\/jats:p>","DOI":"10.1210\/jcemcr\/luad100","type":"journal-article","created":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T16:37:17Z","timestamp":1695400637000},"source":"Crossref","is-referenced-by-count":1,"title":["Metastatic Merkel Cell Carcinoma Within a Cortisol-producing Adrenal Adenoma"],"prefix":"10.1210","volume":"1","author":[{"given":"Lauren","family":"Cutrone","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Mississippi Medical Center , Jackson, MS 39216 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Subauste","sequence":"additional","affiliation":[{"name":"Department of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center , Jackson, MS 39216 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celso","family":"Gomez-Sanchez","sequence":"additional","affiliation":[{"name":"Department of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center , Jackson, MS 39216 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1467-9961","authenticated-orcid":false,"given":"Sarah","family":"Joiner","sequence":"additional","affiliation":[{"name":"Department of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center , Jackson, MS 39216 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"issue":"4","key":"2023102813290252100_luad100-B1","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1102\/1470-7330.2013.0053","article-title":"Adrenal collision tumors and their mimics: multimodality imaging findings","volume":"13","author":"Katabathina","year":"2013","journal-title":"Cancer Imaging"},{"issue":"1","key":"2023102813290252100_luad100-B2","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1245\/s10434-020-08587-3","article-title":"Patterns of metastasis in Merkel cell carcinoma","volume":"28","author":"Song","year":"2021","journal-title":"Ann Surg Oncol"},{"issue":"5","key":"2023102813290252100_luad100-B3","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1210\/jc.2008-0125","article-title":"The diagnosis of Cushing's syndrome: an Endocrine Society clinical practice guideline","volume":"93","author":"Nieman","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"2023102813290252100_luad100-B4","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S2213-8587(21)00178-9","article-title":"Adrenal myelolipomas","volume":"9","author":"Calissendorff","year":"2021","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"4","key":"2023102813290252100_luad100-B5","doi-asserted-by":"crossref","first-page":"271","DOI":"10.4103\/1450-1147.215499","article-title":"Appearance of adrenal myelolipomas on 2-deoxy-2-(18F) fluoro-D-glucose positron emission tomography-computed tomography","volume":"16","author":"Rowe","year":"2017","journal-title":"World J Nucl Med"},{"issue":"3","key":"2023102813290252100_luad100-B6","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1148\/radiol.2383042164","article-title":"Adrenal lesions: characterization with fused PET\/CT image in patients with proved or suspected malignancy\u2014initial experience","volume":"238","author":"Blake","year":"2006","journal-title":"Radiology"},{"issue":"1","key":"2023102813290252100_luad100-B7","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1016\/j.endonu.2013.04.002","article-title":"Myelolipoma associated with adrenocortical adenoma: an unusual cause of Cushing's syndrome","volume":"61","author":"Corpas Jim\u00e9nez","year":"2014","journal-title":"Endocrinol Nutr"},{"issue":"1","key":"2023102813290252100_luad100-B8","doi-asserted-by":"crossref","first-page":"7965","DOI":"10.4076\/1757-1626-2-7965","article-title":"Metastatic adenocarcinoma within a functioning adrenal adenoma: a case report","volume":"2","author":"Martin","year":"2009","journal-title":"Cases J"},{"issue":"4","key":"2023102813290252100_luad100-B9","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/20009666.2017.1362315","article-title":"An exceedingly rare adrenal collision tumor: adrenal adenoma-metastatic breast cancer-myelolipoma","volume":"7","author":"Liu","year":"2017","journal-title":"J Community Hosp Intern Med Perspect"},{"issue":"3","key":"2023102813290252100_luad100-B10","first-page":"286","article-title":"Lung cancer metastasis to adrenocortical adenomas. A chance occurrence or a predilected phenomenon?","volume":"112","author":"Moriya","year":"1988","journal-title":"Arch Pathol Lab Med"}],"container-title":["JCEM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcemcr\/article-pdf\/1\/5\/luad100\/51825571\/luad100.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcemcr\/article-pdf\/1\/5\/luad100\/51825571\/luad100.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T13:29:31Z","timestamp":1698499771000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcemcr\/article\/doi\/10.1210\/jcemcr\/luad100\/7278875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,1]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,9,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jcemcr\/luad100","relation":{},"ISSN":["2755-1520"],"issn-type":[{"value":"2755-1520","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,9]]},"published":{"date-parts":[[2023,9,1]]},"article-number":"luad100"}}