{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:14:37Z","timestamp":1792192477690,"version":"4.4.0"},"reference-count":10,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Amiodarone-induced thyrotoxicosis (AIT) can be difficult to treat since amiodarone's long half-life leads to a persistent effect on thyroid function. We present a case of a 74-year-old male with severe AIT who presented with altered mentation and ultimately required intubation and intensive care for management of thyroid storm. Standard medical therapy for treatment of thyroid storm was initiated immediately, but the patient remained unresponsive with worsening biochemical parameters with increasing total T3 levels and sustained elevated levels of free T4 after 5 days of medical management. Due to the lack of a clinical and biochemical response to conventional medical therapy, the patient was started on plasmapheresis and underwent a total of 7 cycles of plasmapheresis over a period of 10 days. He significantly improved with plasmapheresis and was successfully bridged to a total thyroidectomy, which was completed without complications.<\/jats:p>","DOI":"10.1210\/jcemcr\/luad123","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T23:21:12Z","timestamp":1699399272000},"source":"Crossref","is-referenced-by-count":7,"title":["The Use of Plasmapheresis in a Severe Case of Amiodarone-Induced Thyrotoxicosis"],"prefix":"10.1210","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5431-2057","authenticated-orcid":false,"given":"Tina","family":"Moazezi","sequence":"first","affiliation":[{"name":"Departments of Internal Medicine and Endocrinology, Advocate Lutheran General Hospital , Park Ridge, IL 60068, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9115-9938","authenticated-orcid":false,"given":"Chung-Kay","family":"Koh","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Endocrinology, Advocate Lutheran General Hospital , Park Ridge, IL 60068, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2023,11,3]]},"reference":[{"issue":"3","key":"2023121603012418200_luad123-B1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/0885066613498053","article-title":"Thyroid storm: an updated review","volume":"30","author":"Chiha","year":"2015","journal-title":"J Intensive Care Med"},{"key":"2023121603012418200_luad123-B2","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2012-006696","article-title":"Surviving the storm: two cases of thyroid storm successfully treated with plasmapheresis","volume":"2012","author":"Carhill","year":"2012","journal-title":"BMJ Case Rep"},{"issue":"5","key":"2023121603012418200_luad123-B3","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/jca.21927","article-title":"Therapeutic plasmapheresis for the treatment of thyrotoxicosis: A retrospective multi-center study","volume":"36","author":"Builes-Monta\u00f1o","year":"2021","journal-title":"J Clin Apher"},{"issue":"7","key":"2023121603012418200_luad123-B4","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1001\/jama.1970.03180070041007","article-title":"Thyroid storm treatment with blood exchange and plasmapheresis","volume":"214","author":"Ashkar","year":"1970","journal-title":"JAMA"},{"issue":"3","key":"2023121603012418200_luad123-B5","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/jca.21705","article-title":"Guidelines on the use of therapeutic apheresis in clinical practice\u2014evidence-based approach from the writing committee of the American society for apheresis: the eighth special issue","volume":"34","author":"Padmanabhan","year":"2019","journal-title":"J Clin Apher"},{"issue":"1","key":"2023121603012418200_luad123-B6","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s12020-018-1661-x","article-title":"Therapeutic 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