{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:53:20Z","timestamp":1753883600472,"version":"3.41.2"},"reference-count":10,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In this report we present a case of a 14-year-old girl with type 1 diabetes mellitus (T1DM) who experienced glycemic instability and multiple hormonal deficits, including diabetes insipidus, central hypothyroidism, and central adrenal insufficiency. Brain and sellar magnetic resonance imaging revealed a mass in the suprasellar region, which was confirmed to be a pituitary abscess through transsphenoidal biopsy.<\/jats:p>\n               <jats:p>T1DM is a chronic systemic disease that can lead to suboptimal glycemic control and increased susceptibility to infections. Pituitary abscess is a rare and serious infection that can manifest with nonspecific signs and symptoms, as well as pituitary hormonal deficiencies.<\/jats:p>\n               <jats:p>Currently, after a 6-year follow-up the pituitary hormone deficiencies have resolved apart from persistent partial diabetes insipidus. Through a review of the current literature, we discuss the clinical characteristics of pituitary abscess, the challenges in diagnosing it, and speculate on the potential clinical and pathophysiological relationship between this uncommon infection and T1DM in our patient.<\/jats:p>","DOI":"10.1210\/jcemcr\/luae057","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T20:42:59Z","timestamp":1717447379000},"source":"Crossref","is-referenced-by-count":0,"title":["Diabetes Insipidus Complicating Diabetes Mellitus Type 1: A Pituitary Abscess Diagnosis"],"prefix":"10.1210","volume":"2","author":[{"given":"Barbara","family":"Lionetti","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa , 16132, Genoa , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Minuto","sequence":"additional","affiliation":[{"name":"Pediatric Clinic and Endocrinology Unit, IRCCS Istituto Giannina Gaslini , 16147, Genoa , Italy"},{"name":"Pediatric Clinic and Endocrinology Unit, Regional Center for Pediatric Diabetes, IRCCS Istituto Giannina Gaslini , 16147, Genoa , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9166-1079","authenticated-orcid":false,"given":"Marta","family":"Bassi","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa , 16132, Genoa , Italy"},{"name":"Pediatric Clinic and Endocrinology Unit, IRCCS Istituto Giannina Gaslini , 16147, Genoa , Italy"},{"name":"Pediatric Clinic and Endocrinology Unit, Regional Center for Pediatric Diabetes, IRCCS Istituto Giannina Gaslini , 16147, Genoa , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3567-6118","authenticated-orcid":false,"given":"Flavia","family":"Napoli","sequence":"additional","affiliation":[{"name":"Pediatric Clinic and Endocrinology Unit, IRCCS Istituto Giannina Gaslini , 16147, Genoa , Italy"},{"name":"Pediatric Clinic and Endocrinology Unit, Regional Center for Pediatric Diabetes, IRCCS Istituto Giannina Gaslini , 16147, Genoa , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"issue":"2","key":"2024062702123274500_luae057-B1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1210\/jc.2015-1700","article-title":"ACTH stimulation tests for the diagnosis of adrenal insufficiency: systematic review and meta-analysis","volume":"101","author":"Ospina","year":"2016","journal-title":"J Clin Endocrinol 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