{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T22:42:23Z","timestamp":1775947343327,"version":"3.50.1"},"reference-count":22,"publisher":"The Endocrine Society","issue":"10","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The differential diagnosis between malignant and benign adrenal cortical tumors is challenging, and concurrent androgen and cortisol production should raise\u202f suspicion of a malignant tumor. We present the case of a 36-year-old woman who exhibited pronounced hirsutism, clitoromegaly, and secondary amenorrhea. A contrast-enhanced computed tomography (CT) scan revealed a 35 \u00d7 27\u2005mm right adrenal mass with unenhanced CT attenuation of 40 Hounsfield units (HUs). The mass exhibited absolute and relative washout rates of 50% and 28%, respectively, and was accompanied by a 25 \u00d7 20\u2005mm adenopathy located in the hepatogastric space. Total testosterone was elevated by 247\u2005ng\/dL (8.56\u2005nmol\/L) (normal reference range, 10-75\u2005ng\/dL; 0.34-2.6\u2005nmol\/L). A 1-mg dexamethasone suppression test revealed an elevated serum morning cortisol concentration of 10.57\u2005\u03bcg\/dL (291.58\u2005nmol\/L) (reference range, &amp;lt;1.8\u2005\u03bcg\/dL; &amp;lt;\u202f49.66\u2005nmol\/L). A fluorine-18 fluorodeoxyglucose positron emission tomography\/computed tomography (18F-FDG PET\/CT) scan revealed increased uptake in both the adrenal mass and the adenopathy. Subsequently, the patient underwent an open right adrenalectomy and lymphadenectomy. Histological examination revealed the presence of an adrenal adenoma with myelolipomatous metaplasia, as well as a positive polymerase chain reaction (PCR) for Mycobacterium tuberculosis in the adenopathy.<\/jats:p>","DOI":"10.1210\/jcemcr\/luae171","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T14:52:47Z","timestamp":1727275967000},"source":"Crossref","is-referenced-by-count":2,"title":["Androgen and Cortisol Cosecreting Adrenal Adenoma and Tuberculous Lymphadenitis"],"prefix":"10.1210","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9413-5833","authenticated-orcid":false,"given":"Gabriela","family":"Garza-Garc\u00eda","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n , 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Diego","family":"S\u00e1nchez-Villa","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n , 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavio Enrique","family":"D\u00edaz-Trueba","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n , 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Angel","family":"Lara-Salazar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n , 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"G\u00f3mez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n , 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo Adolfo","family":"Reza-Albarr\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n , 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"issue":"1","key":"2024101805224177700_luae171-B1","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1093\/ejendo\/lvad066","article-title":"European Society of Endocrinology clinical practice guidelines on the management of adrenal incidentalomas, in collaboration with the European Network for the Study 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