{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:53:33Z","timestamp":1753883613213,"version":"3.41.2"},"reference-count":14,"publisher":"The Endocrine Society","issue":"8","license":[{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ovotesticular difference of sex development (OT-DSD) is a rare condition encompassing a broad spectrum of phenotypic variations. We describe a 67-year-old man who presented with complaints of poor urinary stream and hesitancy for the past 6 months. He had normal pubertal development, libido, and erection, but has been experiencing sexual dysfunction and reduced energy over the last 2 years. Physical examination revealed bilateral cryptorchidism with no other genital ambiguities. Laboratory evaluation showed a 46, XY karyotype with hypergonadotropic hypogonadism, and imaging revealed m\u00fcllerian structures with abdominal gonads and a large pelvic mass arising from the right gonad, abutting the bladder. He underwent laparoscopic right gonadectomy and biopsy of the left gonad, which revealed bilateral ovotestes and a serous cystadenofibroma arising from the right ovotestis. Given the low risk of malignancy in OT-DSD, early distinction from other differences of sex development could facilitate the preservation of the gonads, allowing for spontaneous puberty and sustained sexual function.<\/jats:p>","DOI":"10.1210\/jcemcr\/luaf115","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T17:03:54Z","timestamp":1749834234000},"source":"Crossref","is-referenced-by-count":0,"title":["An Unusual and Late Presentation of 46, XY Ovotesticular Difference of Sex Development"],"prefix":"10.1210","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2486-1281","authenticated-orcid":false,"given":"Uthara","family":"Elsa Mathew","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism, Lisie Hospital , Kochi 682017 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chankramath S","family":"Arun","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Lisie Hospital , Kochi 682017 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viju","family":"George","sequence":"additional","affiliation":[{"name":"Department of Urology, Lisie Hospital , Kochi 682017 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinnu","family":"Kurian","sequence":"additional","affiliation":[{"name":"Department of Pathology, Lisie Hospital , Kochi 682017 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Kadungapuram","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Lisie Hospital , Kochi 682017 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