{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T10:43:42Z","timestamp":1759229022937,"version":"3.43.0"},"reference-count":19,"publisher":"The Endocrine Society","issue":"9","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Adrenal myelolipomas are rare, benign lesions containing mature adipose tissue and hematopoietic elements, typically identified incidentally on radiographic imaging. Management of small masses less than 5\u2005cm usually requires no intervention, whereas those exceeding 6\u2005cm in size are classified as \u201cgiant\u201d and can cause mass effect and potentially fatal hemorrhage. Surgery must be considered for masses deemed at risk to cause complications. A 44-year-old man with a history of congenital adrenal hyperplasia presented with giant bilateral adrenal myelolipomas, which on computed tomography (CT) imaging showed significant displacement of the kidneys and compression of the inferior vena cava. Open adrenalectomy was performed, resulting in the resection of a 30.0-cm left adrenal myelolipoma and a 27.5-cm right adrenal myelolipoma. The postoperative course was uneventful. Bilateral adrenal myelolipomas of this size have rarely been reported. Management of such giant adrenal masses requires an individualized treatment approach. Bilateral adrenalectomy proved to be a safe and effective option for this patient after performing shared decision-making regarding quality of life. Highlighted here is the importance of patient-centered care in management of similar benign lesions.<\/jats:p>","DOI":"10.1210\/jcemcr\/luaf169","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T14:01:49Z","timestamp":1752501709000},"source":"Crossref","is-referenced-by-count":1,"title":["Management of Giant Bilateral Adrenal Myelolipomas in Congenital Adrenal Hyperplasia"],"prefix":"10.1210","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5954-3294","authenticated-orcid":false,"given":"Aayush","family":"Purohit","sequence":"first","affiliation":[{"name":"University of South Carolina School of Medicine Greenville , Greenville, SC 29605 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilien","family":"Rappaport","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Prisma Health Upstate Department of Medicine , Greenville, SC 29605 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"2025081304271497600_luaf169-B1","first-page":"311","article-title":"\u00dcber Knochenmarksgewebe in der Nebenniere","volume":"7","author":"Gierke","year":"1905","journal-title":"Zeiglers Beitr Pathol Anat"},{"issue":"1","key":"2025081304271497600_luaf169-B2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/cen.14188","article-title":"Clinical course of adrenal myelolipoma: a long-term longitudinal follow-up study","volume":"93","author":"Hamidi","year":"2020","journal-title":"Clin Endocrinol"},{"key":"2025081304271497600_luaf169-B3","first-page":"665","article-title":"Adrenal myelolipoma","volume":"73","author":"Olsson","year":"1973","journal-title":"Surgery"},{"key":"2025081304271497600_luaf169-B4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1530\/ERC-16-0564","article-title":"Lipomatous tumours in adrenal gland: WHO updates and clinical implications","volume":"24","author":"Lam","year":"2017","journal-title":"Endocr Relat Cancer"},{"issue":"1","key":"2025081304271497600_luaf169-B5","first-page":"728198","article-title":"Giant bilateral adrenal myelolipoma with congenital adrenal hyperplasia","volume":"2014","author":"Al-Bahri","year":"2014","journal-title":"Case Rep Surg"},{"issue":"2","key":"2025081304271497600_luaf169-B6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1210\/jc.2011-2373","article-title":"Giant bilateral myelolipomas in a man with congenital adrenal hyperplasia","volume":"97","author":"McGeoch","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2025081304271497600_luaf169-B7","first-page":"150079","article-title":"Giant myelolipomas and inadvertent bilateral adrenalectomy in classic congenital adrenal hyperplasia","volume":"2015","author":"Kale","year":"2015","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"2025081304271497600_luaf169-B8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1752-1947-5-298","article-title":"Giant secreting adrenal myelolipoma in a man: a case report","volume":"5","author":"Brogna","year":"2011","journal-title":"J Med Case Rep"},{"issue":"6","key":"2025081304271497600_luaf169-B9","doi-asserted-by":"crossref","first-page":"551","DOI":"10.4103\/ijem.IJEM_737_20","article-title":"Giant bilateral adrenal myelolipoma: case report","volume":"24","author":"Roger","year":"2020","journal-title":"Indian J Endocrinol Metab"},{"issue":"8","key":"2025081304271497600_luaf169-B10","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.ijscr.2014.04.001","article-title":"Adrenal myelolipoma: to operate or not? 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